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Current Hypoglycemia News and Events, Hypoglycemia News Articles.
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Researchers examine postpartum hospital readmissions for women with psychiatric conditions
When is the best time to screen obese women for gestational diabetes? The first-ever randomized control trial to address this question is presented at the Society for Maternal-Fetal Medicine's 39th Annual Meeting. (2019-02-11)

NIH study provides answer to long-held debate on blood sugar control after stroke
Doctors all over the world have debated whether intensive glucose management, which requires the use of IV insulin to bring blood sugar levels down to 80-130 mg/dL, or standard glucose control using insulin shots, which aims to get glucose below 180 mg/dL, lead to better outcomes after stroke. Primary results from the Stroke Hyperglycemia Insulin Network Effort (SHINE) study, a large, multisite clinical study provide a clear answer to that question. (2019-02-07)

Investigators study effect of switching insulin medications
In 2015, CareMore Health, an integrated health delivery system and subsidiary of Anthem Inc., piloted an intervention to switch members from analogue to less expensive human insulin. Investigators from Brigham and Women's Hospital have analyzed the results of the program, finding that the switch was associated with only a small, population-level increase -- 0.14 percent -- in hemoglobin A1c, a value that falls within expected biological variation. (2019-01-29)

Cheering on a potential diabetes drug from bench to bedside
Scientists have developed a promising compound that targets a protein well-known to be implicated in type 2 diabetes, which -- unlike different versions of its kind currently under investigation -- proved to be safe and effective in a phase 2 clinical trial of 190 type 2 diabetes patients. (2019-01-16)

New data emphasize importance of avoiding hypoglycemic glucose levels in type 1 diabetes
Researchers have shown that measures of biochemical hypoglycemia in fingerstick blood samples are associated with an increased risk of severe hypoglycemic events. (2019-01-09)

Millions of low-risk people with diabetes may be testing their blood sugar too often
For people with Type 2 diabetes, testing blood sugar levels becomes part of everyday life. But a new study suggests that some of them test more often than they need to. Fourteen percent of people with Type 2 diabetes who don't require insulin are buying enough test strips to test their blood sugar two or more times a day -- when they don't need to test nearly that frequently according to medical guidelines. (2018-12-10)

Fasting for lab tests isn't good for patients with diabetes
Fasting before getting your blood drawn for cholesterol tests is common practice, but new research from Michigan State University shows it is a contributing factor of low blood sugar, or hypoglycemia, in patients who take diabetes medications. (2018-12-04)

Association of area deprivation and regional disparities in the treatment of T1 diabetes
How the autoimmune disease type 1 diabetes is treated also depends on where the patients live in Germany. In socio-economically weaker regions, insulin pumps and long-acting insulin analogs are used less frequently. Here the patients have higher blood glucose levels (HbA1c) and a higher prevalence of overweight. However, the rate of severe hypoglycemia events is lower. This is the result of a study carried out by a team of researchers at the German Center for Diabetes Research (DZD). (2018-11-29)

Glucose binding molecule could transform the treatment of diabetes
Scientists from the University of Bristol have designed a new synthetic glucose binding molecule platform that brings us one step closer to the development of the world's first glucose-responsive insulin which, say researchers, will transform the treatment of diabetes. (2018-11-19)

Researchers find novel mutation affecting YARS causes multisystem disease
Researchers have identified a novel missense mutation in tyrosyl-tRNA synthetase (YARS c.499C>A, p.Pro167Thr) that causes a severe recessive disorder in affected individuals. The report includes detailed clinical characterization of seven related Amish children who were homozygous for the variant. The children all exhibited poor growth, developmental delay, abnormal brain white matter, hearing loss, involuntary eye movements, progressive cholestatic liver disease, pancreatic insufficiency, hypoglycemia, anemia, intermittent excess of protein in urine, recurrent bloodstream infections, and chronic pulmonary disease. (2018-11-06)

Is there a benefit to switching from flash monitoring to RT-CGM for hypoglycemia?
In follow-up to the I HART CGM study, which showed the benefit of real-time continuous glucose monitoring (RT-CGM) compared to flash monitoring for time spent in hypoglycemia among adults with type 1 diabetes at high hypoglycemia risk, researchers conducted an extension trial that assessed the effects of continuing RT-CGM or switching from flash to RT-CGM of the subsequent 8 weeks. (2018-10-12)

Weight loss drug shows positive effect on diabetes
'Now we report that, when added to lifestyle interventions, lorcaserin significantly reduced incidence of diabetes, increased rates of diabetes remission, and reduced the risk of diabetic microvascular complications.' (2018-10-04)

Appetite-suppressant lorcaserin decreases risk of developing diabetes and induces remission of high blood sugar in obese and overweight patients
New research presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD) in Berlin, Germany, and published in The Lancet, shows that the appetite-suppressant drug lorcaserin decreases risk of developing diabetes and increases the rates of remission of high blood sugar. (2018-10-04)

Researchers reveal link between hunger and mood, new study
The study used rats to examine the impact on emotional behavior of a sudden drop in blood sugar. When the rats were given a glucose blocker, researchers found they had higher levels of cortisol. They also showed signs of stress and sluggish behavior similar to a poor mood. To prove the behavior wasn't just a lack of glucose to the muscles, researchers then gave them a common antidepressant and the behavior disappeared. (2018-09-25)

New study provides next clue to prevent dangerous episodes of low blood sugar in diabetics
A new LSU Pennington Biomedical Research Center study reveals that a novel biomarker might give us new answers necessary to creating a diagnostic tool for hypoglycemia-associated autonomic failure (HAAF). No objective diagnostic tool currently exists for this condition which, if left untreated, can lead to ever-worsening and possibly life-threatening episodes of dangerously low blood sugar. (2018-08-10)

Study provides next clue to preventing dangerous episodes of low blood sugar with diabetes
A new LSU Pennington Biomedical Research Center study reveals that a novel biomarker might give us new answers necessary to creating a diagnostic tool for hypoglycemia-associated autonomic failure, or HAAF. No objective diagnostic tool currently exists for this condition which, if left untreated, can lead to ever-worsening and possibly life-threatening episodes of dangerously low blood sugar. (2018-07-30)

Human insulin as safe and effective to treat type 2 diabetes as costlier insulin analogs
Patients with Type 2 diabetes who were treated with the newer generation of insulin analog drugs did not have substantially better outcomes than those treated with less costly human insulin, according to a study by Yale School of Medicine researchers and colleagues at Kaiser Permanente. The study is published in the June 23 issue of Journal of the American Medical Association. (2018-06-26)

Living with the stigma of diabetes
A team at the Research Institute of the McGill University Health Centre (RI-MUHC) report that teen and young adult (aged 14-24 years) type 1 diabetes sufferers often experience stigma, which leads them to neglect treatment and tread dangerously close to suffering medical emergencies. This study is the first of its kind to estimate the stigma prevalence in this age group and type 1 diabetes, which can lead to elevated HbA1c levels and severe hypoglycemia. (2018-06-12)

Thyroid dysfunction may lead to diabetes during pregnancy
Women with thyroid dysfunction in the first half of pregnancy face an increased risk for gestational diabetes, a form of diabetes that is typically diagnosed during the second trimester, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2018-06-07)

Sugars in infant formulas pose risk to babies with inherited metabolic disorder
Babies with inherited intolerance of fructose face a risk of acute liver failure if they are fed certain widely available formulas containing fructose, pediatricians and geneticists are warning. Baby formula manufacturers should remove fructose or sucrose, or explicitly label their products to allow parents to avoid those sweeteners if necessary, the doctors say. (2018-05-17)

Very-low-carb diet shows promise in type 1 diabetes
Very-low-carbohydrate diets can improve blood sugar control in type 1 diabetes, with low rates of hypoglycemia and other complications, according to an online patient survey. The researchers, led by Belinda Lennerz, MD, Ph.D., and David Ludwig, M.D., Ph.D., of Boston Children's Hospital, now call for controlled clinical trials of this approach. Findings were reported in the journal Pediatrics. (2018-05-07)

Study: Use of some antipsychotics during pregnancy may raise risk of gestational diabetes
Women who take certain antipsychotic medications and continue the use of these medications through pregnancy may be at increased risk for gestational diabetes, according to new research published online today by the American Journal of Psychiatry. (2018-05-07)

Review of nearly 500 patient cases shows surgery benefits for congenital hyperinsulinism
A review of nearly 500 cases of infants with severe congenital hyperinsulinism who underwent partial or near-total removal of their pancreas for persistent hypoglycemia at Children's Hospital of Philadelphia (CHOP) showed that surgeons can cure virtually all patients with the focal, or localized, form of the rare genetic disease. (2018-05-07)

Majority of late preterm infants suffer from morbidities resulting in hospital stay
Late preterm infants constitute 70 percent of the preterm population. Common neonatal morbidities are higher in this group compared to term infants. Although this increased risk is attributed to physiological immaturity, recent studies indicate that immaturity itself may not be the sole cause of morbidity as all premature infants experience this risk, but suffer different outcomes. (2018-05-05)

How intestinal bacteria can affect your blood sugar and lipid levels
Intestinal bacteria have attracted recent attention since they were discovered to influence various physiological functions and diseases in humans. Japanese researchers analyzing the influence of changes in intestinal bacteria on sugar and lipid metabolism have found that secondary bile acids produced by intestinal bacteria can influence blood glucose and lipid concentrations as well as parts of their molecular mechanisms. (2018-04-10)

Islet transplantation improves QoL for people with hard-to-control type 1 diabetes
Quality of life for people with type 1 diabetes who had frequent severe hypoglycemia -- a potentially fatal low blood glucose leve -- improved consistently and dramatically following transplantation of insulin-producing pancreatic islets, according to findings published online March 21 in Diabetes Care. The results come from a Phase 3 clinical trial funded by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). (2018-03-21)

Wearable heart rate monitor could signal low blood sugar in type 1 diabetes
A wearable medical patch measuring the beat-to-beat variation in heart rate is a promising device for the early detection of hypoglycemia, or low blood sugar, in type 1 diabetes, according to the researchers who tested the new monitor. Results of their preliminary study will be presented Saturday at ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago. (2018-03-19)

Insulin pump known to be effective in adolescents, adults also benefits children
The MiniMedâ„¢ 670G insulin pump system (Medtronic, Northridge, California) can improve glycemic outcomes in children with type 1 diabetes as young as 7 years of age, according to an industry-funded study. The results will be presented in a poster on Saturday, March 17 at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill. (2018-03-19)

Glucose monitoring helps prevent hypoglycemia in hospitalized heart disease patients
Hospitalized patients with stable coronary artery disease (CAD) may need frequent glucose monitoring to prevent hypoglycemia and death, new research reports. The results will be presented in a poster on Saturday, March 17, at ENDO 2018, the annual 100th meeting of the Endocrine Society in Chicago, Ill. (2018-03-17)

Low blood sugar poses unaddressed threat to people with type 2 diabetes
New research from the Endocrine Society and Avalere Health finds that clinicians lack the resources to identify, assess and manage patients who are at a high risk of developing hypoglycemia, or episodes of dangerously low blood sugar. (2018-03-05)

New glucagon delivery system reduces episodes of post-bariatric surgery hypoglycemia
The number of bariatric surgeries is increasing, as is the incidence of post-bariatric hypoglycemia (PBH). Physicians do not have adequate tools to treat this condition. A smart glucagon device developed by Joslin Diabetes Center and the Harvard School of Engineering and Applied Sciences has been shown to reduce episodes of PBH. (2018-02-08)

Many older individuals with type 2 diabetes are over-treated
In a recent Diabetes, Obesity & Metabolism analysis of individuals aged 70 years with type 2 diabetes, almost 40 percent with recommended HbA1c levels (which indicate blood glucose levels) were over-treated. (2018-01-24)

Continuous glucose monitors warn of low blood sugar threat
Continuous glucose monitors (CGM) can protect individuals who have had type 1 diabetes for years and are at risk of experiencing dangerously low blood sugar by increasing their awareness of the symptoms, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2017-11-28)

Pill for glycemic control for type 2 diabetes shows promise
Among patients with type 2 diabetes, the drug semaglutide taken by pill resulted in better glycemic control than placebo over 26 weeks, findings that support phase 3 studies to assess longer-term and clinical outcomes, as well as safety, according to a study published by JAMA. (2017-10-17)

Insulin pumps associated with lower risk of serious complications among young patients with type 1 diabetes
Compared with insulin injections, insulin pump therapy among young patients with type 1 diabetes was associated with a lower risk of diabetic ketoacidosis and severe hypoglycemia, according to a study published by JAMA. (2017-10-10)

Scientists identify a possible therapeutic target for regulating body weight
A new study published online in The FASEB Journal (http://www.fasebj.org) reveals a novel gene involved in maintaining body weight. (2017-10-04)

Examining the management of diabetes in special populations
A special issue of Current Diabetes Review examining the management of diabetes in special populations: awareness of the needs of ethnic minorities, elderly patients, bariatric surgery patients, those with mental illness, and those being discharged from the hospital. (2017-09-29)

New self-powered paper patch could help diabetics measure glucose during exercise
A new paper-based sensor patch developed by researchers at Binghamton University, State University of New York could allow diabetics to effectively measure glucose levels during exercise. (2017-09-18)

Time to dial back on diabetes treatment in older patients? Study finds 11 percent are overtreated
Almost 11 percent of Medicare participants with diabetes had very low blood sugar levels that suggested they were being over-treated, a new study finds. But only 14 percent of these patients had a reduction in blood sugar medication refills in the next six months. (2017-09-15)

Too many older diabetes patients are being overtreated
Up to 11 percent of older Americans insured through Medicare are receiving too much medication to control their diabetes, and around 7 percent are being undertreated. This is according to a study in the Journal of General Internal Medicine which is published by Springer. (2017-09-14)

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