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Current Immune System News and Events, Immune System News Articles.
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Severe COVID-19 infection linked to overactive immune cells
Samples from the lungs of patients show a runaway immune system reaction could be one mechanism behind severe COVID-19 cases. (2020-10-08)
Blocking immune system pathway may stop COVID-19 infection, prevent severe organ damage
While the world waits eagerly for a safe and effective vaccine to prevent infections from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus behind the COVID-19 pandemic, researchers also are focusing on better understanding how SARS-CoV-2 attacks the body in the search for other means of stopping its devastating impact. (2020-10-08)
Study shows similar antibody response to key SARS-CoV-2 'spike' protein in COVID-19
New research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) shows that antibody responses to related to the key 'spike' protein of the SARS-CoV-2 virus are similar in COVID-19 patients with and without diabetes, boosting hopes that vaccines involving this same protein will have a high chance of being as effective in vulnerable patients with diabetes as they will be in the general population. (2020-10-08)
A step toward a universal flu vaccine
Researchers at MIT and the Ragon Institute of MIT, MGH, and Harvard are now working on strategies for designing a universal flu vaccine that could work against any flu strain. (2020-10-07)
Boosting chickens' own immune response could curb disease
Broiler chicken producers the world over are all too familiar with coccidiosis, a parasite-borne intestinal disease that stalls growth and winnows flocks. (2020-10-07)
Hearts harvested from pigs may soon help solve chronic shortages of these donor organs
An analysis discusses scientific breakthroughs that have overcome obstacles to cardiac xenotransplantation. (2020-10-07)
COVID-19 outcomes in patients with rare inborn immune disorders
Garvan's Prof Stuart Tangye and KU Leuven's Prof Isabelle Meyts have co-led a multi-centre international consortium to assess the severity of COVID-19 in individuals with inborn errors of immunity. (2020-10-06)
Every COVID-19 case seems different; these scientists want to know why
As scientists around the world develop life-saving COVID-19 vaccines and therapies, many are still wondering exactly why the disease proves deadly in some people and mild in others.A new international study led by scientists at La Jolla Institute for Immunology (LJI), The University of Liverpool and the University of Southampton is the first to give a detailed snapshot of how the body's CD4+ T cells respond to the SARS-CoV-2 virus. (2020-10-06)
A small switch with a big impact
Minor changes in immune cells can significantly affect the immune response, scientists of the University of Würzburg have now discovered. (2020-10-05)
Preliminary results of two large immune therapy studies show promise in advanced cervical cancer
COLUMBUS, Ohio - Preliminary results from two independent, phase II clinical trials investigating a new PD-1 (programmed cell death protein 1)-based immune therapy for metastatic cervical cancer suggest potential new treatment options for a disease that currently has limited effective options and disproportionately impacts younger women. (2020-10-05)
IL-21 protein a key part of immune response to central nervous system infections
esearchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system. (2020-10-05)
Researchers zero in on genetic connection to postpartum hemorrhage
Researchers have identified genetic mutations that appear to protect women from severe bleeding after childbirth, a leading cause of maternal death. (2020-10-03)
Vaccine ingredients could be hiding in small molecule libraries
Many vaccines include ingredients called adjuvants that help make them more effective by eliciting a stronger immune response. (2020-10-02)
Cancer immunotherapy 'uniquely suppressed' by liver tumors
Though cancer immunotherapy has become a promising standard-of-care treatment--and in some cases, perhaps a cure--for a wide variety of different cancers, it doesn't work for everyone, and researchers have increasingly turned their attention to understanding why. (2020-10-02)
Scientists map genes controlling immune system 'brakes'
Researchers at Gladstone Institutes, in collaboration with scientists at UC San Francisco (UCSF) and the Technical University of Munich (TUM), have mapped out the networks of genes that help differentiate regulatory T cells from other T cells. (2020-10-01)
Feeding C-section newborns their mother's poop may help build healthy microbiota
A paper published October 1, 2020 in the journal Cell suggests that newborns delivered by cesarean may benefit from drinking a small amount of their mother's feces dissolved in breast milk, because it provides them with beneficial bacteria they would otherwise be exposed to in vaginal birth. (2020-10-01)
Hackensack Meridian CDI scientists find one-two punch for preclinical cancer models
Research findings published Aug. 14, 2020 in the journal Cancer Research suggest that since some cancer treatments can be undermined by epigenetic changes (altered DNA methylation affecting gene expression) in cancer cells before the treatments are even administered, a worthwhile strategy is to administer an epigenetically-acting drug - which can pave the way for more effective subsequent use of immune-acting cancer treatments. (2020-09-30)
Innate lymphoid cells regenerate within lung
Max Planck researcher Dominic Grün teamed up with colleagues from Würzburg headed by Georg Gasteiger and generated a comprehensive atlas of Innate lymphoid cells (ILCs) of the lung. (2020-09-30)
Scientists propose immune cocktail therapy to boost cancer-immunity cycle in multiple aspects
A research team led by Prof. TIAN Huayu from the Changchun Institute of Applied Chemistry (CIAC) of the Chinese Academy of Sciences proposed an innovative immune cocktail therapy that combined ICT along with other therapeutic approaches. (2020-09-30)
Cells sacrifice themselves to boost immune response to viruses
Whether flu or coronavirus, it can take several days for the body to ramp up an effective response to a viral infection. (2020-09-30)
Common antioxidant enzyme may provide potential treatment for COVID-19
Catalase, a naturally occurring enzyme, holds potential as a low-cost therapeutic drug to treat COVID-19 symptoms and suppress the replication of coronavirus inside the body. (2020-09-29)
Mussels connect antibodies to treat cancer
POSTECH research team develops innovative local anticancer immunotherapy technology using mussel protein. (2020-09-29)
Inflammatory gene provides clue to obesity risk
A gene that helps to control inflammation increases the risk of obesity and could be turned off in mice to stop weight gain, a study from The University of Queensland has found. (2020-09-29)
Prostate cancer: immunotherapy offers hope
An antibody for treating advanced prostate cancer improves progression-free survival in patients with metastasised, castration-resistant prostate cancer. (2020-09-29)
New genetic knowledge on the causes of severe COVID-19
A proportion of the most severe COVID-19 cases can be explained by genetic defects in the patients' immune system. (2020-09-29)
Blocking enzyme's self-destruction process may mitigate age-related diseases
Stopping the cannibalistic behavior of a well-studied enzyme could be the key to new drugs to fight age-related diseases, according to a new study published online in Nature Cell Biology. (2020-09-29)
Memory training for the immune system
The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. (2020-09-28)
Strong activation of anti-bacterial T cells linked to severe COVID-19
A type of anti-bacterial T cells, so-called MAIT cells, are strongly activated in people with moderate to severe COVID-19 disease, according to a study by researchers at Karolinska Institutet in Sweden that is published in the journal Science Immunology. (2020-09-28)
Insect Armageddon: low doses of the insecticide, Imidacloprid, cause blindness in insects
Joint research provides important evidence on the role of insecticides on the longevity of insect population. (2020-09-28)
Uncovering a 'suPAR' culprit behind kidney injury in COVID-19
A new observational study finds patients in the hospital for COVID-19 have high levels of soluble urokinase receptor (suPAR), an immune-derived pathogenic protein that is strongly predictive of kidney injury. (2020-09-24)
Scientists trace severe COVID-19 to faulty genes and an autoimmune condition
An international team led by Jean-Laurent Casanova has led to a breakthrough in understanding why only some people develop severe COVID-19: due to faulty genes or misguided antibodies, they lack type I interferons, proteins vital in protecting against viruses. (2020-09-24)
Study reveals higher COVID-19 mortality in men could be explained by differences in circulating proteins and immune system cells
New research presented at the ESCMID Conference on Coronavirus Diseases (ECCVID, online 23-25 September) suggests that the higher risk of poor COVID-19 outcomes in men could be explained by differences in circulating proteins and immune system cells compared with women. (2020-09-24)
Scientists identify dozens of genes allowing cancer cells to evade the immune system
Cancer immunotherapy can be extremely successful but so far has only worked in a fraction of patients and tumour types. (2020-09-23)
Berry good news -- new compound from blueberries could treat inflammatory disorders
Inflammatory bowel disease (IBD), caused by chronic inflammation in the digestive tract linings, can be debilitating and life threatening. (2020-09-23)
Children's immune response more effective against COVID-19
Children and adults exhibit distinct immune system responses to infection by the virus that causes COVID-19, a finding that helps explain why COVID-19 outcomes tend to be much worse in adults, researchers from Yale and Albert Einstein College of Medicine report Sept. (2020-09-22)
Targeting the treatment of autoimmune diseases
A team of researchers from Charité - Universitätsmedizin Berlin and the Deutsches Rheuma-Forschungszentrum (DRFZ) Berlin, a Leibniz Institute, have successfully treated two patients with the autoimmune disease systemic lupus erythematosus. (2020-09-22)
COVID-19 mortality rates higher among men than women
A new review article from Beth Israel Deaconess Medical Center (BIDMC) shows people who are biologically male are dying from COVID-19 at a higher rate than people who are biologically female. (2020-09-22)
Modeling future COVID-19 cases under a variety of immune responses, and with or without vaccines
Researchers who adapted standard epidemiological models to explore how the COVID-19 pandemic trajectory might unfold in the next five years report diverse scenarios ranging from recurring severe epidemics to elimination. (2020-09-21)
Children with COVID-19 show different immune responses, but better outcomes than adults
A comparison of children and adults hospitalized with COVID-19 reveals pediatric patients, who had better outcomes and shorter hospital stays, displayed altered immune responses and more limited production of antibodies against infection. (2020-09-21)
Researchers find diminished response by 'killer' T cells in elderly COVID-19 patients
Although people of any age can become infected with SARS-CoV-2, the virus that causes COVID-19, elderly patients face a higher risk of severity and death than younger patients. (2020-09-21)
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