Current Immunization News and Events

Current Immunization News and Events, Immunization News Articles.
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Global poliovirus risk management and modeling
Launched in 1988, the Global Polio Eradication Initiative (GPEI) stands out as one of the largest, internationally coordinated global public health major projects conducted to date, with cumulative spending of over $16.5 billion for 1988-2018, according to the World Health Organization (WHO). More than 30 years later, stubborn outbreaks of wild poliovirus still occur in Afghanistan and Pakistan, where cases have been increasing since 2018. The global eradication of polio continues to be an elusive goal. (2021-02-16)

New ACIP Adult Immunization Schedule recommends changes to several vaccines, includes interim recomm
The Advisory Committee on Immunization Practices (ACIP) has released its 2021 Recommended Adult Immunization Schedule that includes changes to several vaccines including influenza, hepatitis A, human papillomavirus (HPV); and the measles, mumps and rubella (MMR) vaccine. The schedule also includes interim recommendations for COVID-19 vaccination. The complete schedule, including changes in the vaccine notes section, is being simultaneously published in Annals of Internal Medicine and on the Centers for Disease Control and Prevention (CDC) web site. (2021-02-11)

COVID-19 vaccine from new vaccine platform effective in mice
It is necessary to develop additional COVID-19 vaccines, as different vaccine approaches have their advantages and disadvantages and may work synergistically. Researchers at Karolinska Institutet in Sweden now report that they have developed a prototype vaccine against SARS-CoV-2 using a DNA vaccine platform that is inexpensive, stable, easy to produce, and shows a good safety profile. A study published in Scientific Reports shows that the vaccine induces potent immune responses in mice. (2021-02-04)

Amazon spreads vaccine misinformation, iSchool researchers find
Amazon's search algorithm gives preferential treatment to books that promote false claims about vaccines, according to research by UW Information School Ph.D. student Prerna Juneja and Assistant Professor Tanu Mitra. (2021-02-02)

Vaccine delivered via skin could help in fight against respiratory diseases
Brigham's Thomas Kupper, MD, and co-authors present results from preclinical studies suggesting skin scarification may help generate lung T cells and provide protection against infectious diseases, with implications for prevention of COVID-19. (2021-01-27)

Study: Many summer camps don't require childhood immunizations
Nearly half of summer camps surveyed by researchers didn't have official policies requiring campers be vaccinated, and just 39% mandated staffers be vaccinated. (2021-01-13)

Strategy tested in mice protects against SARS-CoV-2 & coronaviruses that represent human threats
An immunization strategy tested in mice protects against infection from SARS-CoV-2, as well as from potentially emerging animal coronaviruses, researchers say. (2021-01-12)

Single-dose COVID-19 vaccine triggers antibody response in mice
Across the world, health care workers and high-risk groups are beginning to receive COVID-19 vaccines, offering hope for a return to normalcy amidst the pandemic. However, the vaccines authorized for emergency use in the U.S. require two doses to be effective, which can create problems with logistics and compliance. Now, researchers reporting in ACS Central Science have developed a nanoparticle vaccine that elicits a virus-neutralizing antibody response in mice after only a single dose. (2021-01-08)

Global disparities in vaccination persist and leave many children at risk
Even before the COVID-19 pandemic, tens of millions of children worldwide were not receiving basic doses of vaccines. New research finds there continue to be significant disparities in childhood vaccination, and poorer children from under-represented and minority groups in most countries are more likely to be less fully vaccinated with all the recommended immunizations. A special supplement to the American Journal of Preventive Medicine looks at the barriers and challenges that limit or prevent access to vaccines in vulnerable children. (2020-12-22)

US needs clear vaccine distribution strategy to defeat coronavirus
An opinion piece published today online calls for a national vaccine strategy now that COVID-19 vaccines are available. The author writes that a lack of clarity on a distribution plan sets unrealistic expectations among the public and could undermine public trust. But even with a clearly defined strategy in place, vaccinating hundreds of millions of Americans will not be easy. (2020-12-17)

Number of childhood, adolescent vaccinations administered before, after COVID-19 outbreak in Colorado
Using data from the Colorado Immunization Information System, this study suggests vaccination uptake in children and adolescents has decreased in Colorado since the start of the COVID-19 outbreak in that state. (2020-12-07)

Researchers urge priority vaccination for individuals with diabetes
Vanderbilt University Medical Center researchers have discovered individuals with type 1 and type 2 diabetes infected with COVID-19 are three times more likely to have a severe illness or require hospitalization compared with people without diabetes. (2020-12-04)

Immune strategy based on limited information in the network
For cases of global pandemics such as e.g., the current COVID-19, it is impossible to know the full interactions of all individuals and immunize the most centrals. The authors develop a framework for understanding and carrying out efficient immunization (or efficient attack) with limited knowledge. Their findings highlight that an effective way to limit spreading is obtaining information on a few (n approximately 10) individuals and targeting (testing or quarantine) the most central of these. (2020-11-24)

Experts issue recommendations for equitable distribution of COVID-19 vaccine
A group of vaccine experts led by Children's Hospital of Philadelphia (CHOP) has published recommendations to ensure equitable distribution of a COVID-19 vaccine when it becomes available. The framework, published today in Heath Affairs, focuses on five principles the authors believe would strengthen the current immunization delivery system to ensure equitable access to everyone for whom vaccination is recommended. (2020-11-19)

Safety of HPV vaccines in males
A new analysis published in the British Journal of Clinical Pharmacology shows that HPV vaccines are safe and well tolerated in the male population, and the side effects that may occur after immunization are similar in both sexes. (2020-11-04)

Key populations for early COVID-19 immunization in Canada
Canada's National Advisory Committee on Immunization (NACI) recommends vaccinating key populations, such as people at risk of severe illness or death, those at risk of transmitting the virus and essential workers, during the initial rollout of a COVID-19 vaccine in Canada. The preliminary guidance, developed for the Public Health Agency of Canada (PHAC), is published in CMAJ (Canadian Medical Association Journal). (2020-11-03)

Ontario should vaccinate newborns for hepatitis B, study suggests
Not all pregnant women are universally screened for hepatitis B virus (HBV) in Ontario, even though this screening is recommended, and the majority of those who test positive do not receive follow-up testing or interventions, leading to infections of newborns, found new research in CMAJ (Canadian Medical Association Journal). (2020-10-26)

SHEA endorses requiring recommended vaccinations for healthcare personnel, educators and students
All healthcare personnel should be immunized against vaccine preventable diseases recommended by U.S. Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (CDC/ACIP) as a condition of employment, according to a new policy statement by the Society for Healthcare Epidemiology of America. The broad statement of support of the vaccination recommendations, published in the journal Infection Control and Hospital Epidemiology, suggests medical contraindications as the only exception to receiving recommended immunizations. (2020-09-17)

Vaccine that harnesses antifungal immunity protects mice from staph infection
Immunization of mice with a new vaccine consisting of fungal particles loaded with Staphylococcus aureus (S. aureus) proteins protects mice against S. aureus infection, according to a study published August 20 2020 in the open-access journal PLOS Pathogens by David Underhill of Cedars-Sinai Medical Center, and colleague. (2020-08-20)

Flu vaccine induces short-lived bone marrow plasma cells, limiting vaccination longevity
Influenza-specific bone marrow plasma cells - responsible for maintaining the level of protective antibodies following a flu shot - are short-lived, and decline to their pre-vaccination levels within a year, researchers report. (2020-08-13)

Single-shot COVID-19 vaccine protects non-human primates
A leading COVID-19 vaccine candidate, developed at Beth Israel Deaconess Medical Center, creates the groundwork for a newly launched COVID-19 vaccine clinical trial. (2020-07-30)

Parents of 1 in 2 unvaccinated US adolescents have no intention to initiate HPV vaccine
Study results documenting parental hesitancy to begin and complete their child's HPV vaccine series were published in The Lancet Public Health by researchers at The University of Texas Health Science Center at Houston (UTHealth). (2020-07-21)

COVID-19 replicating RNA vaccine has robust response in nonhuman primates
A replicating RNA vaccine, formulated with a lipid-based nanoparticle emulsion, produces antibodies against the COVID-19 coronavirus in mice and primates with a single immunization. These antibodies potently neutralize the virus in young and old animals. The antibody levels induced are comparable to those in recovered COVID-19 patients. This formulation is shelf-stable, with mass-production and distribution advantages. (2020-07-20)

Census of viral spike protein antigens reveals candidates for use in a COVID-19 vaccine
A group of researchers has determined how different proteins associated with SARS-CoV-2 -- the virus that causes COVID-19 -- generate immune responses when given to rabbits as immunizations. (2020-06-08)

With faster cell modeling towards the vaccine and cure for COVID-19
Researchers from the Department of Chemistry, Materials and Chemical Engineering 'Giulio Natta' of the Politecnico di Milano and the Pediatric Research Center, Department of Biomedical and Clinical Sciences 'L. Sacco ', University of Milan have recently published an article in the scientific journal Theranostics, which will help the international scientific community to understand the mechanisms of SARS-CoV-2 infection and to develop vaccines and therapeutic agents against COVID-19. (2020-06-04)

Better patient identification could help fight the coronavirus
In a peer-reviewed commentary published in npj Digital Medicine, experts from Regenstrief Institute, Mayo Clinic and The Pew Charitable Trusts write that matching patient records from disparate sources is not only achievable, but fundamental to stem the tide of the current pandemic and allow for fast action for future highly contagious viruses. (2020-06-02)

Researchers develop high-performance cancer vaccine using novel microcapsules
Scientists from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed a new therapeutic tumor vaccine based on self-healing polylactic acid microcapsules, which can efficiently activate the immune system and inhibit tumor development. (2020-05-22)

Malaria vaccines based on engineered parasites show safety, signs of efficacy
Two vaccines for malaria based on genetically engineered malaria parasites have been found to be safe in humans and show preliminary signs of protection, according to a pair of new phase 1/2a clinical trials. (2020-05-20)

Viral infection: Early indicators of vaccine efficacy
Ludwig-Maximilians-Universität (LMU) in Munich researchers have shown that a specific class of immune cells in the blood induced by vaccination is an earlier indicator of vaccine efficacy than conventional tests for neutralizing antibodies. (2020-05-15)

Molecular signatures can predict the efficacy of malaria vaccines
Molecular signatures before and after immunization can predict vaccine-induced protection, according to a study by ISGlobal, an institution supported by 'la Caixa.' The study analysed the gene expression in peripheral blood cells from individuals immunized with the first malaria vaccine (Mosquirix or RTS,S) and another experimental malaria vaccine. The results, published in Science Translational Medicine suggest that boosting the immune system before vaccination could potentially improve vaccine efficacy. (2020-05-13)

Malaria vaccine trial samples reveal immune benchmarks for achieving protection
By studying samples from two independent clinical trials of malaria vaccines, Gemma Moncunill and colleagues have linked signatures in the immune system to better vaccine protection from the disease in children and adults. (2020-05-13)

The most promising strategies for defeating coronavirus: A review study
Experts from UNC Chapel Hill review possible clinical approaches from antivirals to gene therapy against the virus responsible for COVID-19 and related diseases. (2020-04-24)

Routine childhood vaccination linked to improved schooling among adults in India
In this study, researchers analyzed levels of schooling attainment in years among adults born during or after the implementation of India's Universal Immunization Programme (UIP) (intervention) compared to adults born before the implementation (control). District-level data from the rollout of India's UIP between 1985 and 1990 was matched to schooling data from the National Family Health Survey of India, 2015-2016, a cross-sectional survey that collects information on health and family welfare indicators. (2020-03-10)

Adults don't need tetanus, diphtheria boosters if fully vaccinated as children
Adults do not need tetanus or diphtheria booster shots if they've already completed their childhood vaccination series against these rare, but debilitating diseases, research published in the journal Clinical Infectious Diseases indicates. The study found no significant difference in disease rates between countries that require adults to receive tetanus and diphtheria booster shots and those that don't. (2020-02-25)

Highly active HIV antibody restricts development of viral resistance
A research team led by Univ.-Prof. Dr. Florian Klein of the Institute of Virology of the University Hospital Cologne and the German Center for Infection Research (DZIF) has identified a new highly active antibody targeting HIV. Whereas the development of viral resistance limits the efficacy of previously described HIV antibodies, the newly identified antibody 1-18 can continuously suppress viral replication. 1-18 there-fore has high potential for successful application in the prevention and treatment of HIV infection. (2020-01-31)

Infectious disease experts warn of outbreak risks in US border detention centers
Over the past year, at least seven children have died from diseases including influenza while being detained by the US Department of Homeland Security's Customs and Border Protection (CBP) agency. Infectious disease experts at the University of Maryland School of Medicine (UMSOM) called for protections like influenza vaccinations to prevent serious outbreaks. (2020-01-29)

Integral molecular announces preclinical P2X7 antibody assets for autoimmune disorders
Integral molecular announces preclinical P2X7 antibody assets for autoimmune disorders. (2020-01-09)

From the mouths of babes: Lessons in humility
A poem written by Alexandra M. Sims, M.D., FAAP, will be published Jan. 7, 2020, in JAMA, as part of its series of works by artists and physicians that explore the meaning of healing and illness. (2020-01-07)

Child care centers rarely require flu vaccination for children or their caregivers
Influenza can be especially dangerous for children, who are at greater risk for serious complications from the illness, including hospitalization and even death. Yet child care centers in the US rarely require children or the adults who care for them to be vaccinated against flu, according to a new study published in the Journal of the Pediatric Infectious Diseases Society. (2019-12-12)

Researchers develop approach to alter intestinal microbiota, vaccinate against inflammatory diseases
Targeted immunization against bacterial flagellin, a protein that forms the appendage that enables bacterial mobility, can beneficially alter the intestinal microbiota, decreasing the bacteria's ability to cause inflammation and thus protecting against an array of chronic inflammatory diseases, according to a new study by the Institute for Biomedical Sciences and the Neuroscience Institute at Georgia State University. (2019-12-11)

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