Current Inflammatory Bowel Disease News and Events

Current Inflammatory Bowel Disease News and Events, Inflammatory Bowel Disease News Articles.
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Research shows people with high omega-3 index less likely to die from COVID-19
Researchers with the Fatty Acid Research Institute (FARI) and collaborators at Cedars-Sinai Medical Center in Los Angeles and in Orange County, CA, have published the first direct evidence that higher omega-3 blood levels may reduce risk for death from COVID-19 infection. The report was published in the journal Prostaglandins, Leukotrienes and Essential Fatty Acids on January 20, 2021. (2021-01-26)

3-D printed Biomesh minimizes hernia repair complications
A newly-designed 3D-printed Biomesh effectively minimized postsurgical complications of hernia repair in an animal model. (2021-01-25)

Study finds shorter radiation regimen safe, effective for men with advanced prostate cancer
UCLA researchers found shortening a traditional 45-day course of radiation to a five-day course delivered in larger doses is safe and as effective as conventional radiation for men with high-risk forms of prostate cancer. (2021-01-25)

Newly discovered subset of brain cells fight inflammation with instructions from the gut
A team led by researchers from Brigham and Women's Hospital, has shown that a specific astrocyte sub-population can do the opposite, instead serving a protective, anti-inflammatory function within the brain based on signals regulated by the bacteria that reside in the gut. (2021-01-25)

Exercising muscle combats chronic inflammation on its own
Biomedical engineers at Duke University have demonstrated that human muscle has an innate ability to ward off damaging effects of chronic inflammation when exercised. The discovery was made possible through the use of lab-grown, engineered human muscle, demonstrating the potential power of the first-of-its-kind platform in such research endeavors. (2021-01-22)

NSAIDs might exacerbate or suppress COVID-19 depending on timing, mouse study suggests
New research shows that non-steroidal anti-inflammatory drugs (NSAIDs) reduced both antibody and inflammatory responses to SARS-CoV-2 infection in mice. The study appears this week in the Journal of Virology, a publication of the American Society for Microbiology. (2021-01-22)

COVID-19, influenza and suicide fuel increase in deaths among ICE detainees
Thirty-five people have died in the custody of US Immigration and Customs Enforcement (ICE) since April 2018, with a seven-fold increase in deaths even as the average daily population decreased by nearly a third between 2019 and 2020, a new USC study shows. (2021-01-21)

Important cause of preeclampsia discovered
New findings show that cholesterol crystals in the uterine wall are the villain that researchers have been looking for. These crystals cause intensified inflammation in people who become ill. (2021-01-21)

New study on the role of monocytes in sarcoidosis
The cause of the inflammatory lung disease sarcoidosis is unknown. In a new study, researchers at Karolinska Institutet in Sweden have investigated whether a type of immune cell called a monocyte could be a key player in sarcoidosis pathogenesis and explain why some patients develop more severe and chronic disease than others. The study, which is published in The European Respiratory Journal, opens new possibilities for future diagnostic and therapeutic methods. (2021-01-21)

Developmental origins of eczema and psoriasis discovered
Scientists have created a highly detailed map of skin, which reveals that cellular processes from development are re-activated in cells from patients with eczema and psoriasis inflammatory skin diseases. The study in Science offers potential new drug targets for treating these painful skin diseases and provides a new understanding of inflammatory disease. Part of the global Human Cell Atlas initiative, the research could also provide a template for regenerating healthy skin in the laboratory. (2021-01-21)

Study reveals new insights into the link between sunlight exposure and kidney damage
A new collaborative study from researchers at the Geisel School of Medicine at Dartmouth and the University of Washington and published in the Proceedings of the National Academy of Sciences (PNAS), reveals unexpected insights into how skin exposure to ultraviolet light can worsen clinical symptoms in autoimmune diseases such as lupus. (2021-01-21)

New trial finds arthritis drug no better than standard care for severe covid-19
Adding the arthritis drug tocilizumab to standard care for patients in hospital with severe or critical covid-19 is no better than standard care alone in improving clinical outcomes at 15 days, finds a new trial published by The BMJ today. (2021-01-20)

Scientists discover link between nicotine and breast cancer metastasis
Scientists at Wake Forest School of Medicine have found that nicotine promotes the spread of breast cancer cells into the lungs. (2021-01-20)

Inflammation caused by scorpion venom should be blocked immediately, study shows
In an article published in Nature Communications, Brazilian researchers show for the first time that in severe cases of scorpion envenomation it is the neuroimmune reaction triggered by the venom that leads to death. (2021-01-20)

Rush researchers demonstrate success with new therapy for COVID-19
A new therapy developed by researchers at Rush University Medical Center is showing success as a way to prevent COVID-19 symptoms in mice. (2021-01-19)

Fried food intake linked to heightened serious heart disease and stroke risk
Fried-food intake is linked to a heightened risk of major heart disease and stroke, finds a pooled analysis of the available research data, published online in the journal Heart. (2021-01-18)

Simple, cheap test can help save lives from colorectal cancer
New research has demonstrated that a simple, cheap test can help identify who is at risk of developing colorectal cancer, aiding early diagnosis and potentially saving lives. (2021-01-18)

Scientists reveal mechanism that causes irritable bowel syndrome
KU Leuven researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study, carried out in mice and humans, was published in Nature. (2021-01-13)

New insights into the control of inflammation
Wistar scientists discovered that EGR1inhibits expression of pro-inflammatory genes in macrophages. The discovery expands the understanding of how macrophages are set off and deactivated in the inflammatory process, which is critical in many normal and pathological conditions. (2021-01-13)

Low fitness linked to higher psoriasis risk later in life
In a major register-based study, scientists at University of Gothenburg, Sweden, have now demonstrated a connection between inferior physical fitness in young adults and elevated risk of the autoimmune disease psoriasis. For the male recruits to compulsory military training who were rated as the least fit, the risk of developing psoriasis later was 35 percent higher than for the fittest. (2021-01-12)

Healthcare Nutrition Council leads the way on medical food discussions
Medical foods help patients manage their nutritional needs, yet it can be very difficult for patients to have access to them. In August 2019, the Healthcare Nutrition Council (HNC), in partnership with the American Society for Nutrition (ASN), held the Medical Foods Workshop: Science, Regulation, and Practical Aspects. (2021-01-12)

High doses of saccharin don't lead to diabetes in healthy adults, study finds
For those trying to live a healthy lifestyle, the choice between sugar and artificial sweeteners such as saccharin can be confusing. A new study led by researchers at The Ohio State University Wexner Medical Center and The Ohio State University College of Medicine found the sugar substitute saccharin doesn't lead to the development of diabetes in healthy adults as previous studies have suggested. (2021-01-12)

Turbo boosters for the immune system
Immunologist Prof. Dr. Olaf Groß of the Medical Center - University of Freiburg receives a Proof of Concept Grant from the European Research Council (ERC) for his project IMMUNOSTIM. (2021-01-11)

Researchers engineer novel disease model to identify potential targets for ulcerative colitis drugs
As reported in Nature Communications, researchers from Cleveland Clinic's Lerner Research Institute have developed a novel, patient-derived model of ulcerative colitis, which will help advance studies into new treatments for the chronic inflammatory bowel disease. The team used the model to identify a promising target that could be inhibited to slow disease progression. (2021-01-11)

Birmingham research paves the way for new anti-fibrotic therapy for glaucoma
Researchers showed that novel low molecular weight dextran-sulphate, ILB®, can normalise matrix deposition inside the eye and lower IOP in a pre-clinical model of human glaucoma, paving the way for new anti-fibrotic therapies to be developed for the disease. (2021-01-07)

COVID-19 outcomes for patients on immunosuppressive drugs on par with non- immunosuppressed patients
People taking immunosuppressive drugs to prevent organ transplant rejection or to treat inflammatory or autoimmune diseases do not fare worse than others on average when they are hospitalized with COVID-19. (2021-01-07)

Treating an autoimmune disease in mice with an mRNA vaccine
Christina Krienke and colleagues have designed an mRNA vaccine that delayed the onset of and reduced the severity of multiple sclerosis-like disease in mice. (2021-01-07)

Study: e-cigarettes trigger inflammation in the gut
Chemicals used for vaping break down zipper-like junctions between cells in the gut, leading to chronic inflammation and potential for other health concerns. (2021-01-07)

New research finds ginger counters certain autoimmune diseases in mice
The main bioactive compound of ginger root lowers autoantibody production and helps halt disease progression in mice with antiphospholipid syndrome and lupus. (2021-01-06)

LSU Health New Orleans discovers potential new RX strategy for stroke
Research conducted at LSU Health New Orleans Neuroscience Center of Excellence reports that a combination of an LSU Health-patented drug and selected DHA derivatives is more effective in protecting brain cells and increasing recovery after stroke than a single drug. (2020-12-30)

New research may explain severe virus attacks on the lungs
In some cases, immune cells in the lungs can contribute to worsening a virus attack. In a new study, researchers at Karolinska Institutet in Sweden describe how different kinds of immune cells, called macrophages, develop in the lungs and which of them may be behind severe lung diseases. The study, which was published in Immunity, may contribute to future treatments for COVID-19, among other diseases. (2020-12-30)

Blood vessel cells implicated in chronic inflammation of obesity
DALLAS - Dec. XX, 2020 - When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with obesity. Now, UT Southwestern scientists have discovered a type of cell responsible, at least in mice, for triggering this inflammation in fat tissue. Their findings, published in Nature Metabolism, could eventually lead to new ways to treat obesity. (2020-12-30)

Multi-population risk scores could improve risk prediction for inflammatory bowel diseases, study finds
New study illustrates how studying diverse populations can help predict patient outcomes and reduce health disparities (2020-12-24)

Increased meat consumption associated with symptoms of childhood asthma
Substances present in cooked meats are associated with increased wheezing in children, Mount Sinai researchers report. (2020-12-22)

Researcher uses machine learning to demonstrate that DNA impacts cancer risk
University of Calgary researcher uses machine learning to demonstrate that DNA impacts cancer risk. Team identifies seven DNA fingerprints or patterns that define cancer risk. One of the seven germlines offers protection from developing cancer, and the other six germlines present a greater risk for cancer. It is the first time scientists have described these highly-specialized biological patterns applicable to cancer risk. Discovery refines the long-held views of why people get cancer. (2020-12-22)

Potential preventative treatment demonstrated for Crohn's disease
A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease. (2020-12-21)

Pacify the protein and win over a disease
Will it be enough to pacify the activity of certain proteins in order to hold back the development of many dangerous diseases including Alzheimer's disease? An article on a breaking through discovery has just been published in PNAS, a prestigious magazine of American Academy of Sciences. Its first author is Karolina Mikulska-Ruminska, Dr., a biophysicist from Nicolaus Copernicus University in Torun (Poland). The article refers to the mechanisms of the activities of the immune system under inflammatory conditions. (2020-12-21)

New study: available drugs can prevent rejection and tissue injury after transplantation
Controlling inflammation after transplantation of organs, cells, or tissues is critical for graft survival; however, it can be difficult. Continuing injuries due to chronic rejection can be particularly problematic. Now, a team of researchers from Albert Einstein College of Medicine report that neutralizing the cell signaling molecule, tumor necrosis factor (TNF), can prevent cascades of injurious molecules and signals after cell transplantation in The American Journal of Pathology, published by Elsevier. (2020-12-21)

Researchers expose power of enzyme on key immune cells
Communication, serendipity and an enzyme called DOT1L have all combined to produce some exciting findings into the immune system's B cells and T cells by two groups of Monash Biomedicine Discovery Institute (BDI) scientists. These could result in further studies into a target for asthma and allergies, and fundamental work exploring the formation of immunity itself. (2020-12-16)

Molecules derived from omega-3 can regenerate inflamed periodontal tissue
An in vitro study by a Brazilian researcher shows that maresin and resolvin synthesized from fatty acid stimulate periodontal ligament stem cells even in the presence of inflammation (2020-12-16)

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