Current Kidney Cancer News and Events | Page 2

Current Kidney Cancer News and Events, Kidney Cancer News Articles.
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Scoring system to redefine how U.S. patients prioritized for liver transplant
Researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are collaborating with faculty at the University of Pennsylvania to develop a risk score that more comprehensively prioritizes liver cancer patients for transplantation. (2021-01-13)

Mechanisms in the kidney that control magnesium and calcium levels discovered
The gene KCTD1 directs production of a protein that functions in the kidney to maintain a normal balance of magnesium and calcium in blood. Loss of KCTD1 impairs the ability of the kidney to properly absorb magnesium and calcium from urine in the kidney, leading to abnormally low magnesium and calcium blood levels, thereby triggering the parathyroid glands to secrete excess parathyroid hormone that in turn leads to metabolic bone disease. (2021-01-12)

First-degree relative with kidney disease increases disease risk by three-fold
In a large population-based family study, family history of kidney disease was strongly associated with increased risk of chronic kidney disease. (2021-01-12)

Fetal-maternal discordance in APOL1 genotype contributes to preeclampsia risk
Fetal APOL1 kidney risk alleles are associated with increased risk for preeclampsia in African Americans and maternal fetal genotype discordance is also associated with this risk. (2021-01-12)

Prevalence of patients receiving dialysis in China may exceed 800,000 by 2025
Study projects that prevalence of patients receiving dialysis in China will increase from 384.4 patients per million (PPM) in 2017 to 629.7 PMP in 2025 with a predicted 874,373 patients receiving dialysis in 2025. (2021-01-12)

Ferroptosis resistance in cancer: An emerging crisis of new hope
Announcing a new publication for BIO Integration journal. In this opinion article the authors Daiyun Xu, Yonghui Lü, Yongxiao Li, Shengbin Li, Zhe Wang and Junqing Wang from Sun Yat-Sen University, Guangzhou, China discuss ferroptosis resistance in cancer. (2021-01-08)

Deep learning helps predicting occult peritoneal metastasis in stomach cancer
A new study led by the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences shows that deep learning can help predicting the occult peritoneal metastasis in stomach cancer. It provides a novel and noninvasive approach for stomach cancer patients and may inform individualized surgical management of stomach cancer. (2021-01-07)

Shiga toxin's not supposed to kill you
E. coli food poisoning is one of the worst food poisonings, causing bloody diarrhea and kidney damage. But all the carnage might be just an unintended side effect, report researchers from UConn Health. Their findings might lead to more effective treatments for this potentially deadly disease. (2021-01-06)

Dental experts discover biological imbalance is the link between gum and kidney disease
An imbalance of the body's oxygen producing free radicals and its antioxidant cells could be the reason why gum disease and chronic kidney disease affect each other, a new study led by the University of Birmingham has found. (2021-01-05)

In-utero exposures associated with increased risk of thyroid cancer
A recent study shows that thyroid cancer is related to in-utero exposures. (2021-01-05)

COVID-19's impact on cancer prevention and control in Africa
When the COVID-19 pandemic reached Africa, the continent was already struggling to deal with another public health crisis - a growing cancer epidemic characterized by more than one million new cancer cases and nearly 700,000 deaths per year. (2020-12-31)

Stopping RAS inhibitors tied to worse outcomes in patients with chronic kidney disease
Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such patients. Researchers at Karolinska Institutet now show that although stopping the treatment is linked to a lower risk of requiring dialysis, it is also linked to a higher risk of cardiovascular events and death. The results are published in The Journal of the American Society of Nephrology. (2020-12-29)

Study finds patients with kidney failure are ready and willing to use mobile health
* In a survey of adults with kidney failure who were receiving dialysis, most owned mobile devices and had intermediate or advanced mobile health proficiency. * The main reasons for using mobile health were for making appointments, communicating with healthcare personnel, and obtaining laboratory results. (2020-12-22)

Virtual kidney transplant evaluation allows patients to be evaluated from home
A virtual telehealth platform is allowing the surgery program at the Medical University of South Carolina to evaluate and wait-list patients for kidney transplantation despite reductions in direct, in-person health care visits brought about by the COVID-19 pandemic. (2020-12-21)

Oral contraceptive pills protect against ovarian and endometrial cancer
A comprehensive study from Uppsala University, involving more than 250,000 women, shows that oral contraceptive use protects against ovarian and endometrial cancer. The protective effect remains for several decades after discontinuing the use. The study is published in the journal Cancer Research. (2020-12-17)

Impaired blood vessel and kidney function underlie heart disease risk in people with HIV
People living with human immunodeficiency virus (HIV) have impaired blood vessel function, which increases risk of heart and blood vessel-disease. The increased heart disease risk is especially pronounced in people with HIV who also have kidney disease. The increased heart disease risk remains regardless of HIV severity or use of antiretroviral therapy. (2020-12-17)

Proenkephalin (penKid®) included in the ADQI consensus statements publication as functional kidney biomarker for the management of AKI patients
The Acute Disease Quality Initiative (ADQI) recommends the use of novel biomarkers for AKI management, including functional biomarkers as penKid®. (2020-12-16)

Too many donor kidneys are discarded in U.S. before transplantation
a large portion of the discarded kidneys would function acceptably if transplanted, according to a new study from a team led by researchers in the Perelman School of Medicine at the University of Pennsylvania and the Paris Translational Research Center for Organ Transplantation. (2020-12-15)

COVID-19 patients at higher risk of death, health problems than those with flu
A deep dive into federal data by researchers at Washington University School of Medicine in St. Louis reveals a clearer distinction between COVID-19 and the flu: Among hospitalized patients, COVID-19 was associated with an increased need for ventilators, more admissions into intensive care units, longer hospital stays and nearly five times the risk of death than faced by those with the flu. (2020-12-15)

Study finds paediatric cancer patients at no greater risk of severe COVID-19 infection
Children with cancer who test positive for COVID-19 do not appear to be at an increased risk of severe COVID-19 infection compared to healthy children, according a new UK study. (2020-12-14)

One-year kidney allograft outcomes do not differ by hepatitis C status of donor
Study published in AJKD shows that kidney allograft outcomes one year post-transplantation in hepatitis C virus (HCV)-negative recipients do not differ by the HCV status of the donor. (2020-12-14)

Low blood pressure during hemodialysis may indicate peripheral vascular disease
Using a large nationwide registry of patients receiving maintenance hemodialysis, this study published in the American Journal of Kidney Diseases found that higher frequency of low blood pressure episodes during hemodialysis was associated with a higher incidence of diagnosed peripheral arterial disease. (2020-12-11)

Calibrating kidney function for cancer patients
A new model to evaluate kidney function can help clinicians find the right balance between treating cancer and avoiding chemotherapy's dangerous side effects. (2020-12-10)

Nearly 72% of Black patients with gynecologic cancer and COVID-19 were hospitalized for the virus compared with 46 percent of non-Blacks
COVID-19 deaths among Black patients with gynecologic cancer disproportionately higher compared to non-Black patients. (2020-12-09)

UL, Ireland, research finds promising treatment to protect kidney function in diabetes
A clinical trial involving researchers at University of Limerick, Ireland has demonstrated the potential benefits of new drugs in protecting kidney function in diabetes. (2020-12-09)

Ability to predict C-diff mortality nearly doubled with new guidelines
Updated national guidelines for treating infections caused by the deadly superbug Clostridioides difficile (C. diff) have been examined and approved by a nationally renowned C. diff researcher at University of Houston and his team of students. (2020-12-09)

Glyphosate can create biomarkers predicting disease in future generations
Exposure to the widely used weed-killer glyphosate makes genetic changes to rats that can be linked to increased disease in their grandchildren and great-grandchildren. These glyphosate-induced changes to sperm from exposed rats could be used as biomarkers for determining propensity in subsequent generations for prostate and kidney diseases as well as obesity and incurring multiple diseases at once. (2020-12-09)

Large US study confirms COVID-19 complications: lung, kidney and cardiovascular issues
A large study of patients in the United States who contracted coronavirus disease 2019 (COVID-19) confirms many complications of the disease, according to new research in CMAJ (Canadian Medical Association Journal). (2020-12-08)

Researchers create framework to help determine timing of cancer mutations
UCLA researchers studying cancer evolution have created a framework to help determine which tool combinations are best for pinpointing the exact timing of DNA mutations in cancer genomes. (2020-12-07)

Kidney injury in diabetic ketoacidosis linked to brain injury
Researchers have identified factors that make children with diabetic ketoacidosis more likely to experience acute kidney injury. Analyzing data from a large, multicenter clinical trial, the researchers also found that children who experience acute kidney injury are more likely to also experience subtle cognitive impairment and demonstrate lower IQ scores, suggesting a pattern of multiple organ injury. (2020-12-04)

Patients with kidney disease may delay AVF creation
Many patients start hemodialysis with temporary vascular access despite regular kidney care and pre-dialysis education. Delay is often related to patient choice but research on patients' perspectives is limited. In this study, researchers surveyed pre-dialysis patients and their family members about their perceptions of chronic kidney disease (CKD) and their intentions to undergo access creation. They also report on a new survey instrument to measure attitudes towards hemodialysis preparation. (2020-12-03)

Rethinking race and kidney function
Removing race from clinical tools that calculate kidney function could have both advantages and disadvantages for Black patients. (2020-12-02)

Kidney disease leading risk factor for COVID-related hospitalization
An analysis of Geisinger's electronic health records has revealed chronic kidney disease to be the leading risk factor for hospitalization from COVID-19. (2020-12-02)

AI predicts which drug combinations kill cancer cells
A machine learning model developed in Finland can help us treat cancer more effectively. (2020-12-01)

Cancer cases are rising in adolescents and young adults
Cancer cases in adolescents and young adults have risen by 30% during the last four decades, with kidney cancer rising at the greatest rate, according to researchers at Penn State College of Medicine. The team said further research into screening, diagnosis and treatment are needed to address the growing trend in this age group. (2020-12-01)

Oncotarget launches special collection on breast cancer
Breast Cancer Collection published in honor of breast cancer awareness. (2020-12-01)

A tricky kidney puzzle
By analyzing the gene expression of single cells, algorithms are able to not only reconstruct their original location in the tissue, but also to determine details about their function. Teams led by Kai Schmidt-Ott and Nikolaus Rajewsky have published their findings in JASN, using the kidney as an example. (2020-11-27)

Survival protein may prevent collateral damage during cancer therapy
Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies. The 'cell survival protein', called BCL-XL, was required in laboratory models to keep kidney cells alive and functioning during exposure to chemotherapy or radiotherapy. Kidney damage is a common side effect of these widely used cancer therapies, and the discovery has shed light on how this damage occurs at the molecular level. (2020-11-25)

RASi associated with reduced risk of KRT compared with CCB in CKD patients
In a population-based Swedish database, researchers studied the clinical outcomes of starting renin-angiotensin system inhibitor (RASi) or calcium channel blockers (CCB) in 2,458 patients with CKD G4-5. Compared with CCB, RASi initiation was associated with a lower risk of KRT, but similar risks of mortality and major adverse cardiovascular events. These findings suggest that RASi initiation might slow the progression of kidney disease compared with CCB in patients with advanced CKD, and offer similar cardiovascular protection. (2020-11-24)

Non-invasive electrolyte levels' measuring method can prevent sudden cardiac death
Researchers from Kaunas University of Technology (KTU), Lithuania came up with the idea on how to measure fluctuating blood potassium levels non-invasively, through electrocardiogram. The researchers claim that their method may become a digital biomarker in the future for managing electrolyte levels. This would be a huge step towards preventing potentially life-threatening conditions among people who suffer from chronic kidney disease. (2020-11-23)

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