Current Kidney Cancer News and Events | Page 25

Current Kidney Cancer News and Events, Kidney Cancer News Articles.
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Using hepatitis C-infected donor kidneys could reduce time on dialysis for transplant patients with HCV
Transplanting hepatitis C-infected dialysis patients with HCV-positive donor organs and then treating the infection later is more effective, cheaper and shortens organ wait time. (2018-07-09)

Extended tamoxifen therapy may increase risk of endometrial cancer
There is clear evidence that extended adjuvant tamoxifen therapy for 10 years reduces local recurrence and improves breast cancer-free survival in women with oestrogen receptor-positive breast cancer. (2018-07-05)

Gene therapy method developed to target damaged kidney cells
Research led by Washington University School of Medicine in St. Louis has shown, in mice, that genetic material can be delivered to damaged cells in the kidneys, a key step toward developing gene therapy to treat chronic kidney disease. The potentially fatal condition affects 30 million Americans, most of whom don't realize they have chronic kidney disease. (2018-07-05)

Availability of family and friends key factor in deciding organ transplant suitability
The availability of a supportive network of family and friends is a key factor in deciding on a person's suitability for an organ transplant, reveals research published online in the Journal of Medical Ethics. (2018-06-28)

For dialysis patients with AFib, a newer blood thinner may provide a safer option
A new study finds a newer blood thinner may be a safer choice for reducing stroke risk in those who have both end-stage kidney disease and atrial fibrillation. (2018-06-28)

Fluorescent molecules reveal how cancer cells are inhibited
A team of researchers at Lund University in Sweden has developed a fluorescent variant of a molecule that inhibits cancer stem cells. Capturing images of when the molecule enters a cell has enabled the researchers, using cell-biological methods, to successfully describe how and where the molecule counteracts the cancer stem cells. (2018-06-25)

Researchers find prostate cancer drug byproduct can fuel cancer cells
A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with an alternate therapy. In a newly published study, researchers found that abiraterone, a common prostate cancer drug, yields high-levels of a testosterone-like byproduct in men with advanced disease who have a specific genetic variant. (2018-06-25)

Inhaled nitric oxide may reduce kidney complications from heart surgery
Administration of nitric oxide gas during and for 24 hours following heart surgery decreased the risk of patients developing acute and chronic kidney problems, a randomized, controlled trial conducted in China found. (2018-06-22)

Human immune 'trigger' map paves way for better treatments
A discovery about how human cells are 'triggered' to undergo an inflammatory type of cell death could have implications for treating cancer, stroke and tissue injury, and immune disorders. A research team from the Walter and Eliza Hall Institute in Melbourne identified the molecular trigger in human cells that drives necroptosis, and implicated defects in this molecular trigger as potentially playing a role in cancer development. (2018-06-21)

Medicaid expansion helps low-income patients get on transplant waitlist before dialysis
In states that expanded Medicaid under the Affordable Care Act to cover more low-income individuals, there was an increase in the number of Medicaid beneficiaries who were preemptively waitlisted to receive a kidney transplant. Medicaid expansion was associated with greater gains racial and ethnic minorities in being listed pre-emptively on the transplant waitlist compared with whites. (2018-06-21)

Reduction in protein in the urine is a treatment goal in children with kidney disease
The blood pressure-lowering medication ramipril reduced protein excretion -- or proteinuria -- in children with chronic kidney disease. Greater reductions in proteinuria during the first months of treatment were linked with a lower risk of kidney disease progression. (2018-06-21)

Medicaid Expansion increased low-income patient access to kidney transplants
States that fully implemented Medicaid expansion under the Affordable Care Act saw significant increases for preemptive kidney transplant listings among black and Hispanic patients. (2018-06-21)

First major study comparing robotic to open surgery published in The Lancet
The first comprehensive study comparing the outcomes of robotic surgery to those of traditional open surgery in any organ has found that the surgeries are equally effective in treating bladder cancer. (2018-06-21)

An emerging drug discovery approach to combat cancer
This review paper will cover recent advances in the development of chemotherapeutic agents against several metabolic targets for cancer therapy, including glucose transporters, hexokinase, pyruvate kinase M2, glutaminase, and isocitrate dehydrogenase. (2018-06-21)

Can older adults safely donate kidneys?
With increasing organ demand, living kidney donation from older donors has become more common. (2018-06-20)

Putting the brakes on metastatic cancer
A groundbreaking discovery by University of Alberta researchers has identified previously-unknown therapeutic targets that could be key to preventing the spread of cancer. In a study published in Nature Communications, the team found that by inhibiting several newly identified gene targets they could block more than 99.5 per cent of cancer metastasis in living cells. (2018-06-20)

Potential to replace race as a risk factor for kidney-transplant failure
Marva Moxey-Mims, M.D., FASN, says APOLLO study researchers hope that clarifying the role of the APOL1 gene in kidney-transplant failure could lead to fewer discarded kidneys, which could boost the number of available kidneys for patients awaiting transplants. (2018-06-20)

Cell-free DNA profiling informative way to monitor urinary tract infections
Using shotgun DNA sequencing, Cornell University researchers have demonstrated a new method for monitoring urinary tract infections (UTIs) that surpasses traditional methods in providing valuable information about the dynamics of the infection as well as the patient's biological response. (2018-06-20)

Researchers identify method to diagnose cancer in patients with early onset diabetes
Patients diagnosed with pancreatic cancer can develop elevated blood sugar levels up to three years before their cancer diagnosis, according to the results of a study by Mayo Clinic researchers published the journal Gastroenterology. (2018-06-20)

Mayo Clinic discovers gene mutations linked to pancreatic cancer
Six genes contain mutations that may be passed down in families, substantially increasing a person's risk for pancreatic cancer. That's according to Mayo Clinic research published in the June 19 edition of the JAMA. However, because researchers found these genetic mutations in patients with no family history of pancreatic cancer, they are recommending genetic testing for all pancreatic cancer patients as the new standard of care. (2018-06-19)

Genomics offers new treatment options for infants with range of soft tissue tumors
The genetic causes of a group of related infant cancers have been discovered by scientists at the Wellcome Sanger Institute, the University of Wuerzburg and their collaborators. Whole genome sequencing of tumours revealed mutations which are targetable by existing drugs used to treat lung cancer and melanoma. The results have implications for clinical practice and the diagnosis of rare cancers in infants, and could lead to new, targeted treatment options for these children. (2018-06-18)

Recent clinical trial finds tamsulosin not effective in kidney stone passage
Research published in JAMA Internal Medicine found that tamsulosin does not significantly effect patient-reported passage or capture of kidney stones. (2018-06-18)

Diabetes diagnosis may signal early pancreatic cancer in older African-Americans, Latinos
A new study from the Keck School of Medicine of USC shows that African-Americans and Latinos who are diagnosed with diabetes after age 50 have a more than threefold risk of developing pancreatic cancer. (2018-06-17)

Protein analysis may reveal new cancer treatment targets
Researchers have used lab technology called mass spectrometry to study the proteins expressed by human cancer cells. (2018-06-15)

Greater levels of vitamin D associated with decreasing risk of breast cancer
Researchers at University of California San Diego School of Medicine suggest higher levels of vitamin D are associated with decreasing risk of breast cancer. Their epidemiological study is published in the June 15 online issue of PLOS ONE, in collaboration with Creighton University, Medical University of South Carolina and GrassrootsHealth, an Encinitas-based nonprofit organization that promotes vitamin D research and its therapeutic benefits. (2018-06-15)

Fish 'umbrella' protects stem cells from sun
Stem cells that make blood cells in fish flourish in the shade provided by a newly discovered cellular 'umbrella' that keeps them safe from UV damage. (2018-06-13)

Why we make blood cells in our bones
In humans and other mammals, the stem cells that give rise to all blood cells are located in the bone. But in fish, blood stem cells are found in the kidney. Since the late 1970s, when biologists first realized that blood develops in a specific location in the body -- the 'blood stem cell niche' -- they have wondered why different creatures have evolved to carry out this function in different locations. (2018-06-13)

Children with kidney disease show blood flow changes in brain
Blood flow changes in the brains of children, adolescents and young adults with chronic kidney disease may explain why many face a higher risk of cognitive impairment, according to a new study. (2018-06-12)

Does cancer increase risk of diabetes?
Developing cancer was associated with increased risk for later diabetes in a nationally representative sample of the Korean general population. (2018-06-07)

In kidney disease patients, illicit drug use linked with disease progression and death
Among individuals with chronic kidney disease, hard illicit drug use was associated with higher risks of kidney disease progression and early death. Tobacco smoking was associated with a higher risk of early death. Alcohol drinking was associated with a lower risk of early death. (2018-06-07)

'Lipofilling' technique found safe for reconstruction after breast cancer surgery
Autologous fat transfer, also known as 'lipofilling,' is a minimally invasive procedure in which the plastic surgeon uses the patient's own fat obtained by liposuction to perform breast reconstruction. (2018-06-06)

Avoiding catastrophe: Yeast study reveals clues to maintaining genome size
Study reveals an unexpected role for a well-known protein machinery in maintaining the correct DNA content with implications for cancer and other diseases. (2018-06-06)

Older breast cancer patients in England less likely to survive
Older women diagnosed with breast cancer in England are less likely to survive their disease than those in Belgium, Poland, Ireland and the Netherlands according to research published today in the British Journal of Cancer. (2018-06-06)

Common diabetes drug found safe for most diabetics with kidney disease
Results of a large-scale study suggest that the oral diabetes drug metformin is safe for most diabetics who also have chronic kidney disease (CKD). The study of more than 150,000 adults by Johns Hopkins Medicine investigators found that metformin's association with the development of a life-threatening condition called lactic acidosis was seen only among patients with severely decreased kidney function. (2018-06-05)

Mayo Clinic researchers take a step closer to developing a DNA test for liver cancer
A group of researchers from Mayo Clinic and Exact Sciences Corporation have completed a phase II study comparing a set of DNA markers to alpha fetoprotein as a method to test for liver cancer. The researchers presented their findings today at the 2018 Digestive Disease Week conference in Washington, D.C. (2018-06-05)

A great majority of Mozambican adolescent girls are willing to be vaccinated against HPV
A study in Mozambique reveals that a majority of adolescent girls interviewed would be willing to get vaccinated against Human Papilloma Virus (HPV) if the vaccine was available in the country. These results are encouraging with regard to vaccine introduction and reducing mortality associated with cervical cancer in Mozambique. The investigation was led by the Manhiça Health Research Center (CISM) and ISGlobal, an institution supported by (2018-06-04)

Timing is everything to build kidneys from scratch
Perfectly punctual or fashionably late, it takes all kinds to build a kidney. So it is for stem cells as USC scientists building kidney tissue discovered timing is critical as the precise arrival of progenitor cells dictates their form and function in the kidney. The finding will help fabricate kidney components for use in drug tests and treatment of renal disease. (2018-06-04)

Experimental drug restores some bladder function after spinal cord injury, study finds
An experimental drug that blocks abnormal neural communication after spinal cord injury could one day be the key to improving quality of life by improving bladder function, new research suggests. (2018-06-04)

Cancer fighting effects of aspirin revealed in bowel tumor study
Researchers at the University of Edinburgh have shed light on how taking aspirin can help to stave off bowel cancer. (2018-06-04)

Is exercise associated with lower risk of death for adult survivors of childhood cancer?
Vigorous exercise is associated with reductions in the risk of death among adult survivors of childhood cancer. (2018-06-03)

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