Current Knee Replacement News and Events

Current Knee Replacement News and Events, Knee Replacement News Articles.
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ECMO/CRRT in the treatment of critically ill SARS-CoV-2 pneumonia patients
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.1267, Hai Zou and Shengqing Li from the Institute of Pulmonary and Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai, China consider ECMO/CRRT combined support in the treatment of critically ill SARS-CoV-2 pneumonia patients. (2021-01-22)

Do antidepressants help chronic back pain and osteoarthritis?
Antidepressants are commonly used worldwide to treat pain, however new research from the University of Sydney shows they offer little to no help for people suffering chronic back pain and osteoarthritis and may even cause harm. (2021-01-20)

Antidepressants largely ineffective for back pain and osteoarthritis
Antidepressant drugs are largely ineffective for back and osteoarthritis pain, despite being widely used for these conditions, suggests a review of the evidence published by The BMJ today. (2021-01-20)

Target discovered that halts osteoarthritis-type knee cartilage degeneration
In a mouse study, researchers used nanotechnology and previous knowledge of a protein pathway to significantly reduce knee cartilage degeneration and pain (2021-01-15)

Neither 'meniscal' nor 'mechanical' symptoms predict findings on knee arthroscopy
Orthopaedic surgeons have traditionally been taught that certain types of knee symptoms indicate damage to specialized structures called the menisci. But these ''meniscal'' and ''mechanical'' symptoms do not reflect what surgeons will find at knee arthroscopy, reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer. (2021-01-14)

Researchers identify nanoparticles that could deliver therapeutic mRNA before birth
Researchers at Children's Hospital of Philadelphia and the School of Engineering and Applied Science at the University of Pennsylvania have identified ionizable lipid nanoparticles that could be used to deliver mRNA as part of fetal therapy. The proof-of-concept study, published today in Science Advances, engineered and screened a number of lipid nanoparticle formulations for targeting mouse fetal organs and has laid the groundwork for testing potential therapies to treat genetic diseases before birth. (2021-01-13)

Rice model offers help for new hips
Rice University engineers design a computational model that will ultimately serve as the engine to predict how long a hip implant could last for a specific patient. The unique model incorporates fluid dynamics and the physics of implant wear and aims to streamline trial-and-error in the design of future implants. (2021-01-11)

Perceiving prosthesis as lighter thanks to neurofeedback
Transmitting sensory signals from prostheses to the nervous system helps leg amputees to perceive prosthesis as part of their body. While amputees generally perceive their prostheses as heavy, this feedback helps them to perceive the prostheses as significantly lighter, ETH researchers have shown. (2021-01-08)

Shriners Hospitals for Children study reveals new link to arthritis
A new study by investigators at the Shriners Hospital for Children -- St. Louis suggests the damaging effects of obesity are not due to body weight but rather come from something much smaller - biochemical signals released by fat cells. (2021-01-08)

Stopping RAS inhibitors tied to worse outcomes in patients with chronic kidney disease
Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such patients. Researchers at Karolinska Institutet now show that although stopping the treatment is linked to a lower risk of requiring dialysis, it is also linked to a higher risk of cardiovascular events and death. The results are published in The Journal of the American Society of Nephrology. (2020-12-29)

Despite recommendations, patients with treatment-resistant hypertension rarely tested for primary al
A retrospective cohort study found that testing for primary aldosteronism in patients with treatment-resistent hypertension was rare and also associated with higher rates of evidence-based treatment and better longitudinal blood pressure control. The findings are published in Annals of Internal Medicine. (2020-12-28)

Remote monitoring leads to 4x decline in returns to hospital after joint surgery
The rate of hospital readmissions for hip and knee replacement patients declined from roughly 12 percent to 3 percent when they were enrolled in a ''hovering'' program (2020-12-21)

Female athletes in WNBA don't return to elite performance for at least 2 years after ACL surgery
Study findings of ACL injuries in WNBA athletes sets return to sport expectations for all female athletes (2020-12-21)

Robots could replace real therapy dogs
Robotic animals could be the 'pawfect' replacement for our real-life furry friends, a new study published today by the University of Portsmouth has found. (2020-12-10)

Risk of serious complications during knee replacement 73% higher when a tourniquet is used
The risk of developing serious complications following a knee replacement could be up to 73% higher when a tourniquet is used, compared to surgery without a tourniquet. Serious complications during knee replacement surgery are rare. However, researchers at the University of Warwick found that 5.9% of patients whose operations involved a tourniquet had serious complications needing additional health care, compared to 2.9% in those operated on without a tourniquet. (2020-12-08)

Replacing red meat with plant foods may reduce the risk of heart disease
Replacing red meat with high quality plant foods such as beans, nuts, or soy may be associated with a modestly reduced risk of coronary heart disease (CHD), suggests a study published by The BMJ today. (2020-12-02)

Scoring system improves screening for "dual" heart disease
Aortic stenosis is one of the most common heart valve defects. As well as conventional valve replacement involving open-heart surgery, a less invasive procedure has now been available for some time in the form of transcatheter aortic valve replacement (TAVR). (2020-11-24)

RASi associated with reduced risk of KRT compared with CCB in CKD patients
In a population-based Swedish database, researchers studied the clinical outcomes of starting renin-angiotensin system inhibitor (RASi) or calcium channel blockers (CCB) in 2,458 patients with CKD G4-5. Compared with CCB, RASi initiation was associated with a lower risk of KRT, but similar risks of mortality and major adverse cardiovascular events. These findings suggest that RASi initiation might slow the progression of kidney disease compared with CCB in patients with advanced CKD, and offer similar cardiovascular protection. (2020-11-24)

Are high-protein total diet replacements the key to maintaining healthy weight?
The results of a study published in The American Journal of Clinical Nutrition suggest that high-protein total diet replacements are a promising nutritional strategy to combat rising rates of obesity. In particular, the study provides further evidence that diets with a higher proportion of protein might offer a metabolic advantage compared to a diet consisting of the same number of calories, but with a lower proportion of protein. (2020-11-18)

Racket sports may worsen knee arthritis
Racket sports like tennis and racquetball appear to accelerate knee joint degeneration in overweight people with osteoarthritis, according to a study being presented at the annual meeting of the Radiological Society of North America (RSNA). (2020-11-17)

Novel technique 'stuns' arthritis pain in shoulder and hip
A novel outpatient procedure offers lasting pain relief for patients suffering from moderate to severe arthritis in their hip and shoulder joints, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA). Researchers said the procedure could help reduce reliance on addictive opiates. (2020-11-16)

New research reveals potential treatment to delay and manage osteoarthritis
Osteoarthritis (OA), a widely acknowledged cause of disability that affects patients' quality of life and has significant economic impact through healthcare costs and loss of earnings. In a novel study researchers have identified cytoplasmic localized histone deacetalyse 6 (HDAC6) as a promising therapeutic target to postpone development of and possibly treat OA using the HDAC6 inhibitor Tubastatin A. They report their results in The American Journal of Pathology, published by Elsevier. (2020-11-12)

Researchers 3D print biomedical parts with supersonic speed
Forget glue, screws, heat or other traditional bonding methods. A Cornell University-led collaboration has developed a 3D printing technique that creates cellular metallic materials by smashing together powder particles at supersonic speed. (2020-11-10)

WFIRM scientists create hybrid tissue construct for cartilage regeneration
Wake Forest Institute for Regenerative Medicine scientists have developed a method to bioprint a type of cartilage that could someday help restore knee function damaged by arthritis or injury. (2020-11-09)

Study compares racial disparities in unilateral versus bilateral knee replacement
Analyzing data from the NIS - Healthcare Cost and Utilization Project database, researchers at Hospital for Special Surgery (HSS) found that African Americans were much less likely to undergo bilateral knee replacement compared to white patients. Regarding in-hospital complication rates, investigators found no significant difference. (2020-11-09)

HSS presents innovative research at 2020 ACR Annual Meeting
At this year's American College of Rheumatology virtual meeting, Hospital for Special Surgery (HSS) presented exciting research related to rheumatology and orthopedic surgery. The research focuses on the diagnosis of renal disorders, the risk of venous thromboembolism after total knee replacement (TKR), and the care of pediatric and young adult patients with rheumatologic diseases. There are also studies related to the care of rheumatology patients during the COVID-19 pandemic. (2020-11-09)

Rapid test shows 'solid performance' for diagnosing infection around joint implants
The recently FDA-authorized alpha-defensin lateral flow test is a highly accurate, ten-minute test for diagnosis of periprosthetic joint infection (PJI) - a serious and costly complication of total joint replacement, reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer. (2020-11-09)

Investigators discover unique immune cells in patients with checkpoint inhibitor-induced arthritis
A study from investigators at Hospital for Special Surgery (HSS) and Brigham and Women's Hospital in Boston has found that the synovial fluid and blood of people experiencing checkpoint inhibitor-induced arthritis is populated by a type of T cells rarely seen in people with other types of inflammatory arthritis. The findings are being presented at the virtual American College of Rheumatology annual meeting. (2020-11-08)

Tough, strong and heat-endure: Bioinspired material to oust plastics
Being tougher, stronger and more adaptive to heat, a new bioinspired material is here to overtake petroleum-based plastics, thanks to researchers' work on an easy and scalable manufacture method. (2020-11-08)

Warfarin use significantly increases risk of knee and hip replacement in people with OA
New research shows that use of warfarin is associated with a significantly greater risk of knee and hip replacements in patients with OA. (2020-11-06)

Steroid injections do not hasten the need for knee replacement
New research shows that corticosteroid injections for knee OA treatment do not hasten a patient's progression to a total knee replacement when compared with hyaluronic acid injections. Details of this study was presented at ACR Convergence, the American College of Rheumatology's annual meeting. (2020-11-06)

Methotrexate improves function in people with knee OA after 3 months
A new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of treatment with oral methotrexate, adults with primary knee osteoarthritis (OA) with inflammation had significant improvements in physical function and inflammation, a sign that this inexpensive, generic pill may be an important intervention for knee OA. (2020-11-06)

Policy, not tech, spurred Danish dominance in wind energy
In a new study focused on Denmark, a global leader in wind energy - a relatively mature and low-cost renewable technology - researchers found that government policies have been the primary driver of that industry's growth and development. (2020-11-06)

Reducing dementia in patients with rheumatoid arthritis
The incidence of dementia in patients with rheumatoid arthritis is lower in patients receiving biologic or targeted synthetic disease modifying antirheumatic drugs (DMARDs) than in patients who receive conventional synthetic DMARDs, according to a new study. The study was presented at the virtual annual meeting of the American College of Rheumatology. (2020-11-06)

Biomarker combination predicts kidney injury in critically ill children
Researchers at the University of Liverpool have identified a unique method of identifying the early signs of a potentially serious condition known as Acute Kidney Injury (AKI). (2020-11-02)

Compression garments reduce strength loss after training
Regular training enhances your strength, but recovery is equally important. Elastic bandages and compression garments are widely used in sports to facilitate recovery and prevent injuries. Now, a research team from Tohoku University has determined that compression garments also reduce strength loss after strenuous exercise. (2020-10-30)

Knee OA guidance for clinicians simplified and streamlined
Researchers review the similarities and differences between OARSI and ESCEO 2019 guidelines for the management of knee OA and provide a narrative to help steer health-care providers through the complexities of non-surgical management of the disease. (2020-10-29)

Younger knee replacement patients more likely to require reoperation
Knee replacement surgery, also known as total knee arthroplasty (TKA), is increasing among patients 65 and younger. One study projects a potential 183% increase in the number of TKA and revision TKA surgeries by the year 2030 in that age group, raising concerns about poorer clinical outcomes, lower patient satisfaction and diminished joint survival compared to an older patient population. (2020-10-28)

Serum creatinine-to- cystatin C ratio predicts mortality
In patients initiating continuous renal replacement therapy for acute kidney injury, higher serum creatinine-to-cystatin C ratios were associated with lower mortality. (2020-10-21)

More research needed to determine safety of hip and knee steroid injections
Although frequently used to treat painful osteoarthritis of the hip and knee, intra-articular corticosteroid (IACS) injections remain controversial. Questions about whether damage to joints occurs as a result of these injections, which are performed thousands a time each day, persist. (2020-10-20)

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