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Current Leukemia News and Events, Leukemia News Articles.
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'PARP' drug sabotages DNA repair in pre-leukemic cells
Looking for ways to halt the uncontrolled growth of cancer cells, scientists at Johns Hopkins have found that a new class of drugs, called PARP inhibitors, may block the ability of pre-leukemic cells to repair broken bits of their own DNA, causing these cells to self-destruct. (2011-12-12)
B cell receptor inhibitor causes chronic lymphocytic leukemia remission
A new, targeted approach to treating chronic lymphocytic leukemia has produced durable remissions in a Phase I/II clinical trial for patients with relapsed or resistant disease, investigators report at the 53rd Annual Meeting of the American Society of Hematology. (2011-12-11)
Novel experimental agent is highly active in CLL patients, interim study shows
An interim analysis of a phase Ib/II clinical trial indicates that a novel experimental agent for chronic lymphocytic leukemia is highly active and well tolerated in patients who have relapsed and are resistant to other therapy. (2011-12-11)
UH Seidman Cancer Center researchers present at American Society of Hematology Annual Meeting
Researchers from Seidman Cancer Center at University Hospitals Case Medical Center and Case Western Reserve University School of Medicine presented new research findings in 25 presentations this weekend at the 53rd Annual Meeting of the American Society of Hematology at the San Diego Convention Center. (2011-12-10)
Cancer-related pathway reveals potential treatment target for rare pediatric disease
Cancer researchers studying genetic mutations that cause leukemia have discovered a connection to the rare disease cherubism, an inherited facial bone disorder in children. (2011-12-08)
Lessons learned from yeast about human leukemia: The power of basic model organisms in human health
The trifecta of biological proof is to take a discovery made in a simple model organism like baker's yeast and track down its analogs or homologs in (2011-12-05)
Moffitt researchers will be strong participants in American Society of Hematology meeting
When the American Society of Hematology convenes its 53rd Annual Meeting and Exposition on Dec. (2011-12-05)
2011 ASH Annual Meeting to highlight latest hematology research, clinical care breakthroughs
The American Society of Hematology will host more than 20,000 attendees from around the globe at its 53rd annual meeting December 10-13 at the San Diego Convention Center in San Diego, CA. (2011-12-01)
New hope for young leukemia patients?
The development of simple tests to predict a leukemic relapse in young patients is a step closer thanks to researchers from the Sainte-Justine University Hospital Research Center and the University of Montreal. (2011-11-17)
Tamoxifen causes significant side effects in male breast cancer patients
About half of male breast cancer patients who take the drug tamoxifen to prevent their disease from returning report side effects such as weight gain and sexual dysfunction, which prompts more than 20 percent of them to discontinue treatment, according to researchers at the University of Texas MD Anderson Cancer Center. (2011-11-16)
Canadian researchers find potential new leukemia treatment with old antibiotic drug
Clinician-scientists in the Princess Margaret Cancer Program have found a promising approach to treating leukemia, using an old drug in a new way. (2011-11-14)
Regimen may improve cell transplantation outcomes for older adults with blood, bone marrow cancers
Older patients with advanced hematologic malignancies, such as leukemia and lymphoma, who received a conditioning regimen that included minimal-intensity radiation therapy prior to allogeneic (genetically different) hematopoietic cell transplantation (HCT; receipt of bone marrow or stem cells transplant) had survival and progression-free survival outcomes suggesting that this treatment approach may be a viable option for older patients with these malignancies, according to a study in the Nov. (2011-11-01)
Age no longer a barrier to stem cell transplantation for older patients
Age alone no longer should be considered a defining factor when determining whether an older patient with blood cancer is a candidate for stem cell transplantation. (2011-11-01)
Bedside assessment may provide better outcomes for older cancer patients
New research from Wake Forest Baptist Medical Center uses a simple assessment tool to determine how well older adults diagnosed with acute myelogenous leukemia can handle treatment. (2011-10-26)
Compound found in common wart treatment shows promise as leukemia therapy
A new potential leukemia therapy targets only cancer cells, while leaving healthy cells alone. (2011-10-26)
Gene responsible for relapses in young leukemia patients
One of the causes of resistance to cancer treatment in children is now beginning to be elucidated. (2011-10-26)
Researchers do precise gene therapy without a needle
For the first time, researchers have found a way to inject a precise dose of a gene therapy agent directly into a single living cell without a needle. (2011-10-16)
Delayed pediatric appendicitis treatment linked to complications, and even death
An in-hospital delay of appendicitis treatment beyond two days was linked to an increased likelihood of complications, including perforation and abscess formation; longer hospitalization; increased costs; and more rarely, death, according an abstract presented Saturday, Oct. (2011-10-15)
Newly identified DNA repair defect linked to increased risk of leukemia relapse
A newly identified defect in a DNA repair system might leave some young leukemia patients less likely to benefit from a key chemotherapy drug, possibly putting them at greater risk of relapse. (2011-09-26)
Death rate higher in minorities with acute leukemia
Blacks and Hispanics have fewer cases of acute leukemia compared to whites but they die at a substantially higher rate, according to study results presented at the Fourth AACR Conference on The Science of Cancer Health Disparities, held here Sept. (2011-09-19)
Cardiovascular drug may offer new treatment for some difficult types of leukemia
A drug now prescribed for cardiovascular problems could become a new tool in physicians' arsenals to attack certain types of leukemia that so far have evaded effective treatments, researchers say. (2011-09-12)
New mutations in leukemia: Researchers found mechanism that can help design future therapies
An international team of researchers has found a group of mutations involved in T-cell acute lymphoblastic leukemia (T-ALL), and showed that certain drugs, already in clinical use to treat other diseases, can eliminate the cells carrying these mutations. (2011-09-04)
Gene defect that predisposes people to leukemia discovered
Mutations on a gene that regulates the transition of primitive blood-forming cells to white blood cells have been implicated in acute myeloid leukemia and in myelodysplasia, a difficulty in producing white blood cells. (2011-09-04)
UT MD Anderson scientists discover secret life of chromatin
Chromatin -- the intertwined histone proteins and DNA that make up chromosomes -- constantly receives messages that pour in from a cell's intricate signaling networks: Turn that gene on. (2011-09-01)
New research validates clinical importance of leukemia stem cells
Research published today focuses on patients and shows that acute myeloid leukemia (AML) contains rare cells with stem cell properties, called leukemia stem cells (LSC), that are better at predicting clinical outcome than the majority of AML cells, showing for the first time that LSCs are significant not just in experimental models but also in patients. (2011-08-28)
Stop signal for leukemia stem cells
An international team comprising researchers the German Cancer Research Center has discovered that hyperactive signaling of a particular growth factor called IGF1 promotes T-cell acute lymphoblastic lymphoma (T-ALL). (2011-08-23)
Researchers find new hope for treatment of chronic leukemia
While testing a new drug designed to treat chronic leukemia, researchers at Cleveland Clinic discovered new markers that could identify which patients would receive maximum benefit from the treatment. (2011-08-17)
Zinc lozenges may shorten common cold duration
Depending on the total dosage of zinc and the composition of lozenges, zinc lozenges may shorten the duration of common cold episodes by up to 40%, according to a recent Finnish study published in the Open Respiratory Medicine Journal. (2011-08-16)
Stem cells central to pathogenesis of mature lymphoid tumors
New research suggests that blood stem cells can be involved in the generation of leukemia, even when the leukemia is caused by the abnormal proliferation of mature cells. (2011-08-15)
AACR hosts Fourth Annual Science of Cancer Health Disparities Conference
The Fourth AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved will bring together scientists to share the latest findings in genetics, epidemiology and treatment methods to better meet the needs of underserved populations. (2011-08-15)
Genetically modified 'serial killer' T cells obliterate tumors in leukemia patients
In a cancer treatment breakthrough 20 years in the making, researchers from the University of Pennsylvania's Abramson Cancer Center and Perelman School of Medicine have shown sustained remissions of up to a year among a small group of advanced chronic lymphocytic leukemia patients treated with genetically engineered versions of their own T cells. (2011-08-10)
Unconventional hunt for new cancer targets leads to a powerful drug candidate for leukemia
Scientists at Cold Spring Harbor Laboratory have used an unconventional approach to cancer drug discovery to identify a new potential treatment for acute myeloid leukemia (AML), an aggressive blood cancer that is currently incurable in 70 percent of patients. (2011-08-03)
Leukemia drug reverses tamoxifen-resistance in breast cancer cells
Taking a leukemia chemotherapy drug may help breast cancer patients who don't respond to tamoxifen overcome resistance to the widely-used drug, new research from the Kimmel Cancer Center at Jefferson suggests. (2011-08-01)
Key growth factor identified in T cell leukemia
Blocking a growth factor receptor cripples cancer growth in a form of T cell leukemia, according to a study published online on August 1 in the Journal of Experimental Medicine. (2011-08-01)
CSHL scientists reveal mechanism behind 'oncogene addiction' in acute leukemia
Scientists at CSHL have laid bare the mechanism behind oncogene addiction, in mice suffering from a form of leukemia that mimics acute myelogenous leukemia (AML) in humans. (2011-07-31)
UT Southwestern support group's book reaches out to husbands, partners of women battling cancer
A UT Southwestern Medical Center men's support group is intent on filling that gap through its recently published book, Stages, which shares stories of members whose wives battled cancer. (2011-07-28)
Research identifies genes vital to preventing childhood leukemia
Researchers at The University of Western Ontario have identified genes that may be important for preventing childhood leukemia. (2011-07-18)
Ready, go!
Stowers researchers pinpoint the Super Elongation Complex as a major regulator in the coordinated expression of early developmental genes. (2011-07-14)
Bone marrow transplant survival more than doubles for young high-risk leukemia patients
Bone marrow transplant survival more than doubled in recent years for young, high-risk leukemia patients treated at St. (2011-07-14)
Epigenetic pathway and new drug show promise in reversing a hard-to-treat childhood cancer
A difficult-to-treat form of childhood leukemia relies on changes in the structure of DNA -- so-called epigenetic changes -- to wreak genomic havoc within white blood cells, according to one of two studies conducted by a research team at Children's Hospital Boston and Dana-Farber Cancer Institute. (2011-07-11)
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