Current Lifespan News and Events

Current Lifespan News and Events, Lifespan News Articles.
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Expanded spina bifida guidelines cover care from newborn to adult
Globally, nearly 300,000 babies are born with neural tube defects including spina bifida (SB) each year. This openly available special issue of the Journal of Pediatric Rehabilitation Medicine (JPRM) provides 20 important evidence- and consensus-based updates to key sections of the 2018 'Guidelines for the Care of People with Spina Bifida' issued by the Spina Bifida Association (SBA). (2021-02-09)

Aging-US: Sulforaphane promotes C. elegans longevity and healthspan
'The results in this Aging-US research output, indicate that sulforaphane prolongs the lifespan and healthspan of C. elegans through insulin/IGF-1 signaling.' (2021-02-03)

Oncotarget: The goal of geroscience is life extension
Dr. Mikhail V. Blagosklonny from The Roswell Park Cancer Institute said, ''Although we do not know everything about aging, we now know enough to start its pharmacologic suppression using clinically approved drugs.'' (2021-02-02)

Healthy lifespan analysis using nematodes
Researchers have developed an automated measurement system to assess healthy lifespan using nematodes. This system performs a mini-population analysis to classify specific populations of nematodes based on qualitative differences in lifespan. Since there are many similarities between the mechanisms that determine the lifespan of nematodes and humans, this system could make it easier to develop drugs and find foods that extend the healthy lifespan of humans. (2021-01-27)

Scientists develop perovskite solar modules with greater size, power and stability
Researchers from the Okinawa Institute of Science and Technology Graduate University (OIST) have created perovskite solar modules with improved stability and efficiency by using a new fabrication technique that reduced defects. Their findings were published on the 25th January in Advanced Energy Materials. (2021-01-27)

A compound that slows bone loss, and a resource for developing treatments to slow aging
A compound that extends lifespan in a tiny nematode worm slows bone loss in aging mice. That surprising result comes from a longitudinal and functional study of 700 aging mice at the Buck Institute, a project that provides a treasure trove of data for researchers aiming to develop therapeutics to slow aging and age-related diseases. The study is currently online in the Journal of Bone and Mineral Research Plus. (2021-01-26)

How dietary choice influences lifespan in fruit flies
Having a choice of foods may accelerate aging and shorten the lifespan of fruit flies, according to a study published today in the open-access eLife journal. (2021-01-19)

DNA-editing method shows promise to treat mouse model of progeria
Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the genetic variation associated with progeria, a rare genetic disease that causes extreme premature aging in children and can significantly shorten their life expectancy. (2021-01-06)

Blood pressure drug may be key to increasing lifespan, new study shows
A stress response of mitochondria, the part of our cells that produce energy to power bodily functions, is important to a longer life. A team of scientists from Osaka City University, Japan, searched through a chemical ''library'' of existing drugs to find one that can activate this stress response in the worm Caenorhabditis elegans. They found that an anti-hypertension drug called metolazone prolongs C. elegans lifespan, marking the first step in developing anti-aging pharmaceuticals. (2020-12-18)

Still paying for broken smartphone display? Now, It is automatically fixed
Smartphone display repair cost that caused so many people to cry about, it may no longer be an issue to worry about. Research team in South Korea has developed a smartphone display material that can self-heal from damages. (2020-12-17)

Optogenetic method can reveal how gut microbes affect longevity
Optogenetics offers a direct way to manipulate gut bacterial metabolism in a temporally, quantitatively and spatially controlled manner and enhance host fitness. (2020-12-17)

Promising treatment for premenstrual dysphoric disorder, PMDD
The mental symptoms of premenstrual dysphoric disorder improve following treatment with a progesterone receptor modulator, as demonstrated by SciLifeLab researcher Erika Comasco and Professor Inger Sundström-Poromaa, Uppsala University. The mechanism of action of the study drug provides insights into the potential molecular mechanisms underlying this psychiatric disorder and its treatment. (2020-12-10)

Listen to the birds: illegal diet pill DNP might kill you on the long run
DNP, a weight loss agent withdrawn from the market in the late 1930s due to acute toxicity, has become increasingly popular in recent years through online illegal sales. A new study using a lifelong DNP treatment in an avian model found that while no obvious toxic effects were detected on the short to medium-term, DNP reduces lifespan by 20% on the long run. (2020-12-09)

Shuttering fossil fuel power plants may cost less than expected
Decarbonizing US electricity production will require both construction of renewable energy sources and retirement of power plants now operated by fossil fuels. A generator-level model described in the December 4, 2020 issue of the journal Science suggests that most fossil fuel power plants could complete normal lifespans and still close by 2035 because so many facilities are nearing the end of their operational lives. (2020-12-03)

Sestrin makes fruit flies live longer
Researchers identify positive effector behind reduced food intake. (2020-11-24)

New therapeutic approach against leukemia
Using an RNA molecule complex, researchers can prevent retention of cancer stem cell in their tumor supporting niche (2020-10-23)

The unexpected repair function of neutrophils
Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered that neutrophils, the most abundant cells of the innate immune system, have many more functions in the body than previously thought. (2020-10-23)

Ancient tiny teeth reveal first mammals lived more like reptiles
Pioneering analysis of 200 million-year-old teeth belonging to the earliest mammals suggests they functioned like their cold-blooded counterparts - reptiles, leading less active but much longer lives. (2020-10-12)

High throughput screening identifies molecules that reduce cellular stress
A new paper in the journal Science Advances describes the discovery of several promising small molecules that appear to reduce cellular stress in mouse skin cells and could lengthen life. (2020-10-03)

Irregular and long menstrual cycles linked to greater risk of early death
Irregular and long menstrual cycles in adolescence and adulthood are associated with a greater risk of early death (before age 70), finds a study published by The BMJ today. (2020-09-30)

New method allows precise gene control by light
A novel optical switch makes it possible to precisely control the lifespan of genetic ''copies''. These are used by the cell as building instructions for the production of proteins. The method was developed by researchers from the universities of Bonn and Bayreuth. It may significantly advance the investigation of dynamic processes in living cells. The study is published in the journal Nature Communications. (2020-09-25)

Sugar promotes sperm longevity in pig reproductive tract
For many livestock species, artificial insemination (AI) is standard. But it can be tricky to achieve success the first time, thanks to variability in ovulation timing across the herd. A new University of Illinois study identifies a naturally occurring sugar that slows the maturation of sperm in pigs, opening up the possibility of extending sperm storage time within the female reproductive tract and increasing the chances of successful fertilization through AI. (2020-09-17)

Climate crisis ages fish, amphibians and reptiles
Climatic conditions are changing at an unprecedented rate, affecting mainly fish, amphibians and reptiles, ectothermic animals that are unable to generate their own internal heat. With heat waves and rising temperatures, these organisms experience not only increased growth rates and heat stress, but also further ageing. (2020-09-16)

Trees living fast die young
A global analysis reveals for the first time that across almost all tree species, fast growing trees have shorter lifespans. This international study further calls into question predictions that greater tree growth means greater carbon storage in forests in the long term. (2020-09-08)

Linking calorie restriction, body temperature and healthspan
Cutting calories significantly may not be an easy task for most, but it's tied to a host of health benefits ranging from longer lifespan to a much lower chance of developing cancer, heart disease, diabetes and neurodegenerative conditions such as Alzheimer's. A new study from teams led by Scripps Research Professors Bruno Conti, PhD , and Gary Siuzdak, PhD , illuminates the critical role that body temperature plays in realizing these diet-induced health benefits. (2020-09-08)

A naturally-occurring metabolite ups lifespan and compresses late-life morbidity in mice
Middle-aged mice that had the naturally-occurring metabolite alpha-ketaglutarate (AKG) added to their chow had a better 'old age.' They were healthier as they aged and experienced a dramatically shorter time of disease and disability before they died, a first for research involving mammals. Results from the double-blinded study, done at the Buck Institute and published in Cell Metabolism, were based on clinically-relevant markers of healthspan. (2020-09-01)

Small fish populations accumulate harmful mutations that shorten lifespan
Population bottlenecks contribute to the accumulation of several harmful mutations that cause age-related illnesses in killifish - a finding that may help answer a key question about aging. (2020-09-01)

UC Berkeley demographers put COVID-19 death toll into perspective
With over 170,000 COVID-19 deaths to date, and 1,000 more each day, America's life expectancy may appear to be plummeting. But in estimating the magnitude of the pandemic, UC Berkeley demographers have found that COVID-19 is likely to shorten the average US lifespan in 2020 by only about a year. (2020-08-25)

Tinkering with roundworm proteins offers hope for anti-aging drugs
KAIST researchers have been able to dial up and down creatures' lifespans by altering the activity of proteins found in roundworm cells that tell them to convert sugar into energy when their cellular energy is running low. Humans also have these proteins, offering up the intriguing possibilities for developing longevity-promoting drugs. These new findings were published on July 1 in Science Advances. (2020-07-31)

Study reveals intricate details about Huntington's disease protein
The research focuses on axonal transport -- the way in which vital materials travel along pathways called axons inside nerve cells, or neurons. Scientists found that HTT sometimes journeys along these roadways in cellular vehicles (called vesicles) that also carry freight including a protein called Rab4. The research also identified other materials that may be present in these shipments. (2020-07-17)

Blood iron levels could be key to slowing ageing, gene study shows
Genes linked to ageing that could help explain why some people age at different rates to others have been identified by scientists. (2020-07-16)

Researchers discover 2 paths of aging and new insights on promoting healthspan
Scientists have unraveled key mechanisms behind the mysteries of aging. They isolated two distinct paths that cells travel during aging and engineered a new way to genetically program these processes to extend lifespan. Cells embark upon either a nucleolar or mitochondrial path early in life, and follow this ''aging route'' throughout their entire lifespan through decline and death. At the heart of the controls the researchers found a master circuit that guides these aging processes. (2020-07-16)

NREL research points to strategies for recycling of solar panels
Researchers at the National Renewable Energy Laboratory (NREL) have conducted the first global assessment into the most promising approaches to end-of-life management for solar photovoltaic (PV) modules. (2020-07-14)

Scientists may have found one path to a longer life
Mifepristone appears to extend lifespan in evolutionarily divergent species Drosophila and C. elegans in ways that suggest it may do so in humans, as well. (2020-07-10)

Dissecting fruit flies' varying responses to life-extension diet
Changes in a few small molecules in a cell's metabolism might indicate whether a calorie-restricted diet will extend, shorten, or not effect lifespan, a fruit fly study shows. Metabolomics may reveal how calorie-restricted diets affect aging, and how genes and environment influence these responses. (2020-07-09)

Circular RNA makes fruit flies live longer
The molecule influences the insulin signalling pathway and thus prolongs life (2020-07-07)

Research finds new approach to treating certain neurological diseases
A team led by Case Western Reserve University medical researchers has developed a potential treatment method for Pelizaeus-Merzbacher disease (PMD), a fatal neurological disorder that produces severe movement, motor and cognitive dysfunction in children. It results from genetic mutations that prevent the body from properly making myelin, the protective insulation around nerve cells. (2020-07-01)

USC-led study: Protein in mitochondria appears to regulate health and longevity
A new study led by researchers at the USC Leonard Davis School of Gerontology is the first to demonstrate that a tiny protein, humanin, has a big impact on health and longevity in both animals and humans (2020-06-24)

UBC study identifies social and behavioral factors most closely associated with dying
Smoking, divorce and alcohol abuse have the closest connection to death out of 57 social and behavioural factors analyzed in this study. The researchers analyzed data collected from 13,611 adults in the U.S. between 1992 and 2008, and identified which factors applied to those who died between 2008 and 2014. They intentionally excluded biological and medical factors. (2020-06-22)

Otago research reveals how mating influences females' life history and ageing
New University of Otago research provides insight into how males influence their mates' health, growth and fertility. (2020-06-22)

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