Current Lipids News and Events

Current Lipids News and Events, Lipids News Articles.
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Déjà brew? Another shot for lovers of coffee
In a world first genetic study, researchers from the Australian Centre for Precision Health at the University of South Australia found that that long-term, heavy coffee consumption - six or more cups a day - can increase the amount of lipids (fats) in your blood to significantly heighten your risk of cardiovascular disease (CVD). (2021-02-18)

Membrane building blocks play decisive role in controlling cell growth
Lipids are the building blocks of a cell's envelope - the cell membrane. In addition to their structural function, some lipids also play a regulatory role and decisively influence cell growth. This has been investigated in a new study by scientists at Martin Luther University Halle-Wittenberg (MLU). The impact of the lipids depends on how they are distributed over the plasma membrane. The study was published in 'The Plant Cell'. (2021-02-15)

Lipid epoxides target pain, inflammatory pathways in neurons
When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, researchers report. These modified compounds, called epo-NA5HT and epo-NADA, have much more powerful effects than the molecules from which they are derived, which also regulate pain and inflammation. (2021-02-10)

Lipid composition of microalgae of the Kaliningrad Region was determined
Scientists from the Immanuel Kant Baltic Federal University and Kemerovo State University determined the qualitative and quantitative composition of fatty acids that the lipids of microalgae comprise. The results are expected to benefit medical science, cosmetology, energy production and the production of feed additives and functional food. (2021-02-09)

Uncovering how some corals resist bleaching
Colorful coral reefs have suffered from ''bleaching'' due to climate change, but researchers from University of Hawaii and Michigan State University joined forces to uncover why some were resistant to this effect in the hopes to preserve these oceanic wonders. (2021-02-08)

Synthesized very-long-chain polyunsaturated fatty acids improved retinal function in mice
A University of Utah ophthalmologist is investigating how lipids known as VLC-PUFAs could be used to prevent eye disease thanks to a new way to synthesize them for research. (2021-02-04)

Standard water treatment technique removes and inactivates an enveloped virus
Enveloped viruses have been detected in raw sewage and sludge, but scientists still don't fully understand the fate and infectivity of these viruses during water purification at treatment plants. Now, researchers reporting in ACS' Environmental Science & Technology have discovered that a standard water treatment technique, called iron (III) coagulation, and its electrically driven counterpart, iron (0) electrocoagulation, can efficiently remove and inactivate a model enveloped virus. (2021-02-03)

How lipids distribute proteins within cells
Researchers have observed how lipids distribute proteins within cells, a discovery that could open the door to understanding the causes of protein transport related diseases, such as cancer or neurodegenerative diseases (2021-01-29)

Anti-freeze for cell membranes
Mosses and flowering plants took different genetic routes to evolve a similar defense mechanism. (2021-01-25)

Inflammation caused by scorpion venom should be blocked immediately, study shows
In an article published in Nature Communications, Brazilian researchers show for the first time that in severe cases of scorpion envenomation it is the neuroimmune reaction triggered by the venom that leads to death. (2021-01-20)

Temple researchers identify cardiac protein that causes different types of heart failure
Heart damage typically progresses, owing to oxidative stress and toxic lipids that alter heart cell energetics and the heart's ability to function normally. Oxidative stress occurs when harmful oxygen-containing molecules outnumber helpful antioxidants, leading to damaging reactions with proteins, DNA, and other cell components. Temple researchers show that in the heart, Kruppel-like factor-5, fuels both the generation of oxidizing molecules and the accumulation of toxic lipids known as ceramides in the heart, exacerbating heart dysfunction. (2021-01-13)

Scientists reveal how gut microbes can influence bone strength in mice
Gut microbes passed from female mice to their offspring, or shared between mice that live together, may influence the animals' bone mass, says a new study published today in eLife. (2021-01-12)

Want to diagnose brain diseases? A mass spectrometry imaging may one day help you
Researchers from Osaka University used mass spectrometry imaging to quantitate the distribution of fat molecules in mouse brain sections. With further development, this will help medical practitioners reliably diagnose diseases without damaging the tissue. (2021-01-07)

Research shows a few beneficial organisms could play key role in treating type 2 diabetes
Researchers have found that a few organisms in the gut microbiome play a key role in type 2 diabetes, opening the door to possible probiotic treatments for a serious metabolic disease affecting roughly one in 10 Americans. (2021-01-04)

New discovery opens novel pathway for high-titer production of drop-in biofuels
Using an unusual, light-dependent enzyme and a newly discovered enzymatic mechanism, researchers from Aarhus University and Massachusetts Institute of Technology have enabled the biological synthesis of high-yield industry relevant production of climate neutral drop-in fuels from biowaste. The study along with the new discovery has been published in Nature Communications. (2020-12-17)

New study debunks blood type diet
A study published in the Journal of the Academy of Nutrition and Dietetics by researchers with the Physicians Committee for Responsible Medicine -- a nonprofit of 12,000 doctors -- debunks the 'blood type diet' by finding that blood type was not associated with the effects of a plant-based diet on body weight, body fat, plasma lipid concentrations, or glycemic control. (2020-12-04)

Cell membranes in super resolution
For the first time ever, expansion microscopy allows the imaging of even the finest details of cell membranes. This offers new insights into bacterial and viral infection processes. (2020-12-02)

Understanding ion channel inhibition to open doors in drug discovery
Scientists have discovered how drug-like small molecules can regulate the activity of therapeutically relevant ion channels - and their findings could transform ongoing drug development efforts. The study reveals how a drug-like small molecule, called Pico145, binds to the TRPC5 channel, thereby preventing the channel from opening.  (2020-11-23)

Future lake food webs in subarctic have more biomass and contain more omega-3 fatty acids
Subarctic regions are facing rapid changes in climate and land-use intensity. An international research team recently completed an investigation to see how these changes are affecting the food webs and fish communities of lakes in northern Finland. Biomasses and omega-3 fatty acids, EPA and DHA, were determined from the algal producers at the base of food web to large carnivorous fish from 20 lakes along a pronounced climatic and productivity gradient. (2020-10-30)

New study may reveal link to lipids playing a key role in Parkinson's disease
New Parkinson's disease model breaks conventional thinking about the roots of Parkinson's disease and may lead to development of new therapies. (2020-10-16)

Mammalian lipid droplets organize and support innate host immunity
Mammalian lipid droplets -- tiny lipid-filled pockets floating amidst a cell's cytoplasm -- represent an intracellular first line of defense against microbial pathogens, researchers report. (2020-10-15)

Cartilage-Inspired, Lipid-Based and Super Slippery Synthetic Hydrogels
Drawing inspiration from the mechanisms that lubricate the cartilage in our joints over a lifetime of wear, researchers designed extremely slippery hydrogels with self-renewing, lipid-based boundary layers, which result in a near 100-fold reduction in friction and wear over other hydrogels. (2020-10-15)

Unraveling the network of molecules that influence COVID-19 severity
Researchers from the Morgridge Institute for Research, the University of Wisconsin-Madison, and Albany Medical College have identified more than 200 molecular features that strongly correlate with COVID-19 severity, offering insight into potential treatment options for those with advanced disease. (2020-10-12)

Targeting our second brain to fight diabetes
Patrice Cani (UCLouvain) and Claude Knauf (INSERM) have discovered a 'jammer' that blocks communication between the gut and the brain, thus preventing proper regulation of sugar and causing insulin resistance in people with diabetes. They also discovered that a lipid produced by our body helps prevent this dysfunction and regulate sugar level, thus mitigating diabetes and intestinal inflammation. These discoveries, published in the scientific journal GUT, are major, because today one in two Europeans is overweight and one in ten has diabetes. (2020-10-06)

Novel cell membrane model could be key to uncovering new protein properties
Researchers have recently shed light on how cell membrane proteins could be influenced by the lipids around them. By developing a novel type of membrane model, they were able to show that the shape and behavior of a protein can be altered by exposure to different lipid compositions. The research team confirmed the artificial membrane's structure through neutron and x-ray scattering at the Department of Energy's (DOE's) Brookhaven (BNL) and Oak Ridge National Laboratories (ORNL). (2020-09-23)

Researchers find cardiovascular health similarities between chimpanzees, humans
Doctors like to remind patients not to monkey around with their health, suggesting that a good diet and regular exercise improve longevity. (2020-09-21)

Discovery of microbes with mixed membranes sheds new light on early evolution of life
Current research suggests that more complex life-forms, including humans, evolved from a symbiosis event of Bacteria and another single-celled organism known as Archaea. However, evidence of a transition period in which the two organisms mixed where nowhere to be found. That is, until now. In the deep waters of the Black Sea, a team of scientists from NIOZ and Utrecht University found microbes that can make membrane lipids of unexpected origin. (2020-09-17)

How vitamin E acetate might injure vapers' lungs
E-cigarette, or vaping, associated lung injury (EVALI) has sickened thousands of people, most under the age of 35. Studies have linked vitamin E acetate, an oily substance in some vaping liquids, to the disorder. Now, researchers reporting in ACS' Chemical Research in Toxicology have uncovered a possible mechanism: Vitamin E acetate could increase the fluidity of lung surfactant, causing the surfactant layer to collapse, contributing to symptoms such as shortness of breath and lung inflammation. (2020-09-16)

Did our early ancestors boil their food in hot springs?
Scientists have found evidence of hot springs near sites where ancient hominids settled, long before the control of fire. (2020-09-15)

Probiotic skin therapy improves eczema in children, NIH study suggests
An experimental treatment for eczema that aims to modify the skin microbiome safely reduced disease severity and increased quality of life for children as young as 3 years of age, a National Institutes of Health study has found. These improvements persisted for up to eight months after treatment stopped, researchers report in Science Translational Medicine. (2020-09-09)

Pro-inflammatory lipids precede Type 1 diabetes onset in mouse model and children
Type 1 diabetes is an autoimmune disease where immune cells -- led by inflammatory macrophages -- attack and destroy the pancreatic beta cells. It now appears that inflammatory lipid signaling may help provoke this attack. Researchers have identified a proinflammatory lipid profile that precedes development of T1D in a mouse model and in children under age 15 who are at high risk for T1D. This finding may identify candidate lipid therapeutic targets to prevent T1D. (2020-09-09)

Cholesterol's effects on cellular membranes
The findings have far-reaching implications in the general understanding of disease, the design of drug delivery methods, and many other biological applications that require specific assumptions about the role of cholesterol in cell membranes.    (2020-09-08)

Researchers find molecular link between liver disease, insulin resistance
Yale researchers have zeroed in on a molecular link between nonalcoholic fatty liver disease and liver insulin resistance in type 2 diabetes. The findings, reported Sept. 2, 2020 in the journal Cell Metabolism, will help pave the way for new drugs to combat type 2 diabetes and other related metabolic disorders, the authors said. (2020-09-02)

Are all vegetarian diets healthy?
Vegetarian foods are not equally healthy, according to research presented today at ESC Congress 2020. (2020-08-27)

Gut microbes could unlock the secret to healthy ageing
Bacteria and other microorganisms in the digestive tract are linked with dozens of health conditions including high blood pressure, high blood lipids, and body mass index (BMI) according to research presented today at ESC Congress 2020. (2020-08-27)

Archaeology: Ceramic cooking pots record history of ancient food practices
Analysing three components of ceramic cooking pots -- charred remains, inner surface residues and lipids absorbed within the ceramic walls -- may help archaeologists uncover detailed timelines of culinary cooking practices used by ancient civilizations. The findings, from a year-long cooking experiment, are published this week in Scientific Reports. (2020-08-27)

Lipid-Oligonucleotides (LONs) --- Promising materials for bioapplications
Lipid-oligonucleotides (LONs) are promising biological materials with special amphiphilic structures and unique functionalities of two moieties, contributing to different bioapplications (from biosensors to biomedicines). LONs have been employed in cellular microenvironment monitoring and mechanical forces measurements, and have shown potential in developing targeted theranostics as well as controllable nanoreactors. This review will discuss the recent progress of using LONs in various bioapplications and the remaining challenges, while leaving some suggestions for future improvement. (2020-08-20)

Building the batteries of cells
A new study, led by Dr. Ruchika Anand and Prof. Andreas Reichert, Heinrich-Heine-University Duesseldorf, Institute of Biochemistry and Molecular Biology I, Germany, now found that two lipid-binding proteins located inside of mitochondria control the overall stability of these batteries. This study provides the first link between mitochondrial structure, lipids and assembly of large respiratory protein units of mitochondria and their importance in diabetes and heart diseases. (2020-08-11)

Newly discovered mutation could point to heart disease therapeutic target
New work identifies a potential therapeutic target for clogged arteries and other health risks that stem from an excess of harmful fats in the bloodstream. The study opens the door for the design of more specific MTP inhibitors that could reduce circulating triglyceride levels without the risk of unpleasant and serious side effects in the intestines and liver. (2020-08-07)

This fruit attracts birds with an unusual way of making itself metallic blue
Instead of relying solely on pigments, the metallic blue fruits of Viburnum tinus use structural color to reflect blue light, a mechanism rarely seen in plants. Researchers reporting August 6 in the journal Current Biology show that the fruits use lipid nanostructures in their cell walls, a previously unknown mechanism of structural color, to get their striking blue--which may also double as a signal to birds that the fruits are full of nutritious fats. (2020-08-06)

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