Current Longevity News and Events

Current Longevity News and Events, Longevity News Articles.
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Gut microbiome implicated in healthy aging and longevity
The gut microbiome is an integral component of the body, but its importance in the human aging process is unclear. ISB researchers and their collaborators have identified distinct signatures in the gut microbiome that are associated with either healthy or unhealthy aging trajectories, which in turn predict survival in a population of older individuals. The work is set to be published in the journal Nature Metabolism(2021-02-18)

University of Limerick research finds new link between personality and risk of death
Ground-breaking research led by University of Limerick, Ireland has revealed for the first time that the immune system directly links personality to long-term risk of death. (2021-02-17)

Capuchin monkey genome reveals clues to its long life and large brain
An international team of scientists has sequenced the genome of a capuchin monkey for the first time, uncovering new genetic clues about the evolution of their long lifespan and large brains. Published in PNAS, the work was led by the University of Calgary in Canada and involved researchers at the University of Liverpool. (2021-02-15)

Preventing COVID-19 and aging: geroprotector to enhance resilience and vaccine response
Clinical trial to explore the potential of rapalogs to enhance resilience against SARS-CoV-2 infection and reduce the severity of COVID-19 in biologically aged individuals. (2021-02-10)

Male sex, BMI, smoking and depression all increase biological age
A 'biological age' score predicts that being male, overweight, a smoker and having depression all contribute to biological aging, a study published today in eLife reports. (2021-02-09)

Aging-US: Sulforaphane promotes C. elegans longevity and healthspan
'The results in this Aging-US research output, indicate that sulforaphane prolongs the lifespan and healthspan of C. elegans through insulin/IGF-1 signaling.' (2021-02-03)

Potential drug target found for treating rare genetic disorder in children
Scientists have identified a potential new treatment approach for Hutchinson-Gilford progeria syndrome (HGPS), a progressive genetic disorder that causes rapid and premature aging in children. (2021-02-02)

Oncotarget: The goal of geroscience is life extension
Dr. Mikhail V. Blagosklonny from The Roswell Park Cancer Institute said, ''Although we do not know everything about aging, we now know enough to start its pharmacologic suppression using clinically approved drugs.'' (2021-02-02)

Alternate type of surgery may prevent total knee replacement
An underused type of knee surgery in younger patients, called high tibial osteotomy, shows considerable success in reducing the need for total knee replacement, according to new research in CMAJ (Canadian Medical Association Journal) www.cmaj.ca/lookup/doi/10.1503/cmaj.200934. (2021-02-01)

Healthy lifespan analysis using nematodes
Researchers have developed an automated measurement system to assess healthy lifespan using nematodes. This system performs a mini-population analysis to classify specific populations of nematodes based on qualitative differences in lifespan. Since there are many similarities between the mechanisms that determine the lifespan of nematodes and humans, this system could make it easier to develop drugs and find foods that extend the healthy lifespan of humans. (2021-01-27)

Scientists publish a blueprint to apply artificial intelligence to extend human longevity
The international team of artificial intelligence experts and medical doctors propose a framework for the application of next-generation AI to extend human longevity (2021-01-27)

The longevity gene mammalian Indy (mINDY) is involved in blood pressure regulation
Reduced expression of mINDY, which is known to extend life span in lower organisms and to prevent from diet induced obesity, fatty liver and insulin resistance in mice, has now been shown to lower blood pressure and heart rate in rodents. (2021-01-26)

How dietary choice influences lifespan in fruit flies
Having a choice of foods may accelerate aging and shorten the lifespan of fruit flies, according to a study published today in the open-access eLife journal. (2021-01-19)

Youth using e-cigarettes three times as likely to become daily cigarette smokers
University of California San Diego Herbert Wertheim School of Public Health and Human Longevity Sciences researchers report that starting tobacco products, including e-cigarettes, before the age of 18 is a major risk factor for people becoming daily cigarette smokers. (2021-01-11)

Optogenetic method can reveal how gut microbes affect longevity
Optogenetics offers a direct way to manipulate gut bacterial metabolism in a temporally, quantitatively and spatially controlled manner and enhance host fitness. (2020-12-17)

Scientists publish the first human psychological aging clock using artificial intelligence
Scientists at Deep Longevity published the first set of psychomarkers of aging developed using deep learning to track the changes in human psychology and assess the effectiveness of interventions, life events, and external events. The new PsychoAge and SubjAge aging clocks were linked to mortality risk. (2020-12-16)

Critical temperature for tropical tree lifespan revealed
For the first time scientists have provided clear evidence that tropical tree lifespan decreases above a critical temperature threshold. (2020-12-14)

Signs of healthy aging found in ergothioneine telomere study
Signs of healthy aging found in ergothioneine telomere in vitro study, published in the Journal of Dietary Supplements, demonstrating Blue California ErgoActive ergothioneine helped to preserve telomere length and reduced the rate of telomere shortening under oxidative stress. The conclusion suggests ergothioneine helps to support healthy aging. (2020-12-10)

Deep Longevity publishes an epigenetic aging clock of unprecedented accuracy
Longevity startup ''Deep Longevity'' has released a new high-accuracy methylation aging clock -- DeepMAge. It is a neural network that was trained and verified in a collection of >6,000 blood samples from 32 studies. The median absolute error of this aging clock is superior to other methylation clocks: 2.77 years in healthy people. The clock shows association with multiple age-related conditions, including cancer, dementia, and obesity. The authors aim to further develop DeepMAge into a generative model to simulate subcellular aging processes. (2020-12-08)

Study of virus attack rate in Manaus, Brazil, shows outcome of mostly unmitigated epidemic
Researchers studying data from blood donors in Manaus, Brazil, who experienced high mortality from SARS-CoV-2, estimate that more than 70% of the population was infected approximately seven months after the virus first arrived in the city. (2020-12-08)

Octogenarian snapper found in WA becomes oldest tropical reef fish by two decades
An 81-year-old midnight snapper caught off the coast of Western Australia has taken the title of the oldest tropical reef fish recorded anywhere in the world. The octogenarian fish was found at the Rowley Shoals -- about 300km west of Broome -- and was part of a study that has revised what we know about the longevity of tropical fish. (2020-12-01)

Inclusion is key for all to thrive throughout life, report says
When it comes to optimizing 'longevity fitness' through attention to social, health, and wealth aspects of life, many Americans face intractable inequities based on the color of their skin, where they live, their sex, and who they love. The COVID-19 pandemic has further demonstrated the additional impacts affecting these demographics through the increased number of cases and mortality rates. (2020-11-19)

Many unresolved questions remain regarding T cell immunity to SARS-CoV-2
T cell responses are critical for providing early control and clearance of many viral infections, but there remain many unknowns concerning T cell immunity in COVID-19. Some T cell responses may even have a detrimental impact on the clinical outcome and contribute to long COVID, a phenomenon that affects roughly 10% of COVID-19 patients, causing them to experience an array of symptoms for a month or longer. (2020-11-18)

Bursts of exercise can lead to significant improvements in indicators of metabolic health
Short bursts of physical exercise induce changes in the body's levels of metabolites that correlate to, and may help gauge, an individual's cardiometabolic, cardiovascular and long-term health, a study by Massachusetts General Hospital has found. Approximately 12 minutes of acute cardiopulmonary exercise impacted more than 80% of circulating metabolites, including pathways linked to a range of favorable health outcomes, thus identifying potential mechanisms that could contribute to a better understanding of cardiometabolic benefits of exercise. (2020-11-16)

Down Syndrome-associated gene suppresses age-related corneal clouding
Down syndrome and hypercholesterolemia mouse models suggest that the DSCR-1 gene protects against abnormal cornea vascularization and associated blindness by suppressing oxidized LDL cholesterol production and downstream angiogenic signaling during chronic high cholesterol. While the neurological pathology of Down syndrome patients worsens with age, they are less susceptible to age-related vascular diseases. The responsible genes and mechanisms are not yet clear, but DSCR-1 is a strong candidate for a wide range of vascular diseases. (2020-11-05)

In study of 30,000 mild-to-moderate COVID-19 patients, antibody responses can persist for five months
Researchers who studied antibody responses in 30,000 patients with mild-to-moderate COVID-19 report that the patients' antibodies were relatively stable for at least five months. (2020-10-28)

Aged cell variations may control health and onset of age-related diseases
Researchers from Kumamoto University, Japan have proposed that cellular senescence variations during the aging process could lead to control of health and onset of age-related diseases. Based on the characteristics of the secretion of inflammatory cytokines released by aged cells, they hypothesize that there are at least four distinct states of cellular senescence, and that these four states arise from coordinated metabolic and epigenomic changes. (2020-10-26)

Women's expected longevity linked to age at birth of last child
CLEVELAND, Ohio --No one knows for sure how long they will live. A new study, however, suggests that leukocyte telomere length may offer some key insights into a woman's longevity and further demonstrates how maternal age at birth of last child affects telomere length and long-term health. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS). (2020-10-07)

High throughput screening identifies molecules that reduce cellular stress
A new paper in the journal Science Advances describes the discovery of several promising small molecules that appear to reduce cellular stress in mouse skin cells and could lengthen life. (2020-10-03)

Researchers find cardiovascular health similarities between chimpanzees, humans
Doctors like to remind patients not to monkey around with their health, suggesting that a good diet and regular exercise improve longevity. (2020-09-21)

Tracking the working dogs of 9/11
A study of search and rescue dogs led by the School of Veterinary Medicine showed little difference in longevity or cause of death between dogs at the disaster site and dogs in a control group. (2020-09-21)

Older and richer: Old grasslands show high biodiversity and conservation value
Researchers from the University of Tsukuba and Kobe University have found that the long-term, sustained existence of grasslands can increase plant diversity, and can act as an indicator for grasslands of high conservation importance. Old grasslands showed a higher plant diversity than forests and new grasslands, and acted as refuges for native and endangered grassland-dependent plant species. The plant community of old grasslands was shown to be unique, indicating that they are of high conservation priority. (2020-09-10)

Small fish populations accumulate harmful mutations that shorten lifespan
Population bottlenecks contribute to the accumulation of several harmful mutations that cause age-related illnesses in killifish - a finding that may help answer a key question about aging. (2020-09-01)

CPR choices of dialysis patients suggest many lack context
Globally some 2 million people with failed kidneys undergo hemodialysis treatment. Researchers queried 876 dialysis patients about whether, in the event of a cardiac arrest, they would want to be resuscitated. Nearly 85% said they definitely or probably would want CPR. The study's lead author said the findings raise concern that many patients are unaware that their likely outcomes of cardiac arrest, even with resuscitation, are poor, relative to the general population. (2020-08-24)

Flu vaccine induces short-lived bone marrow plasma cells, limiting vaccination longevity
Influenza-specific bone marrow plasma cells - responsible for maintaining the level of protective antibodies following a flu shot - are short-lived, and decline to their pre-vaccination levels within a year, researchers report. (2020-08-13)

Tinkering with roundworm proteins offers hope for anti-aging drugs
KAIST researchers have been able to dial up and down creatures' lifespans by altering the activity of proteins found in roundworm cells that tell them to convert sugar into energy when their cellular energy is running low. Humans also have these proteins, offering up the intriguing possibilities for developing longevity-promoting drugs. These new findings were published on July 1 in Science Advances. (2020-07-31)

Neurons are genetically programmed to have long lives
Most neurons are created during embryonic development and have no ''backup'' after birth. Researchers have generally believed that their survival is determined nearly extrinsically, or by outside forces, such as the tissues and cells that neurons supply with nerve cells. A research team led by Sika Zheng, a biomedical scientist at the University of California, Riverside, has challenged this notion and reports the continuous survival of neurons is also intrinsically programmed during development. (2020-07-24)

Blood iron levels could be key to slowing ageing, gene study shows
Genes linked to ageing that could help explain why some people age at different rates to others have been identified by scientists. (2020-07-16)

A balancing act between immunity and longevity
Changes in the immune system can promote healthy ageing (2020-07-10)

Bats offer clues to treating COVID-19
Bats carry many viruses, including COVID-19, without becoming ill. Biologists at the University of Rochester are studying the immune system of bats to find potential ways to ''mimic'' that system in humans. (2020-07-09)

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