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Current Lung Function News and Events, Lung Function News Articles.
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Markey researchers discover role of nuclear glycogen in non-small cell lung cancers
Researchers at the University of Kentucky Markey Cancer Center have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat non-small cell lung cancers. (2019-09-12)
UK improves cancer survival, but is still behind other high-income countries
Cancer survival in the UK has improved since 1995, although it still lags behind other high-income countries, according to new analysis by the International Cancer Benchmarking Partnership (ICBP), which is managed by Cancer Research UK. (2019-09-11)
IMpower131
Patients with Stage IV squamous non-small cell lung cancer enrolled in clinical trial to test the immunotherapy atezolizumab and chemotherapy against chemotherapy alone experienced a longer survival rate, among a subgroup of patients with high PD-LI. (2019-09-10)
Europeans face significant challenges to participate in lung cancer clinical trials
A survey of patients with lung cancer in several European countries revealed that half did not know what a cancer clinical trial is, and 22% had never heard of a cancer clinical trial. (2019-09-10)
KEYNOTE-024 three-year survival update
First line pembrolizumab monotherapy provides durable long-term overall survival benefit compared to chemotherapy, according to data presented today by Dr. (2019-09-10)
Nurse led follow-up service aids patients with respected early stage lung cancer, improves clinic efficiency
The presence of the specialist nurse within thoracic surgical centers in the United Kingdom increased clinic capacity and efficiency, reduced waiting time for appointments, promoted junior medical training and ensured continuity of care for the patients, according to an analysis reported today by Jenny Mitchell from Oxford University Hospitals NHS Foundation Trust, in Oxford, United Kingdom. (2019-09-10)
Patients taking nivolumab experience five-fold increase in overall survival compared to chemotherapy
Pooled data on two clinical trials demonstrate patients taking nivolumab realized a greater than five-fold increase in five-year overall survival rate compared with the chemotherapy docetaxel. (2019-09-10)
Reconfigurable electronics show promise for wearable, implantable devices
Medical implants of the future may feature reconfigurable electronic platforms that can morph in shape and size dynamically as bodies change or transform to relocate from one area to monitor another within our bodies. (2019-09-10)
Gene coding error found in rare, inherited gene cof lung-scarring disorder linked to short telomeres
By combing through the entire genetic sequences of a person with a lung scarring disease and 13 of the person's relatives, Johns Hopkins Medicine researchers say they have found a coding error in a single gene that is likely responsible for a rare form of the disease and the abnormally short protective DNA caps on chromosomes long associated with it. (2019-09-10)
Researchers pinpoint animal model proteins important in study of human disease
Little is known about the proteins and cellular pathways that lead to the formation of the human heart or the roles various proteins and pathways might play in cardiac disease. (2019-09-10)
Registrational data from LIBRETTO-001 trial
Selpercatinib was granted Breakthrough Therapy Designation by the US Food & Drug Administration in 2018 after initial data from the clinical trial LOXO-292 Investigated to Block RET-altered Tumors (LIBRETTO-001) showed the therapy demonstrated robust anti-tumor activity in a group of RET fusion-positive non small cell lung cancer patients, as well as strong evidence of durability. (2019-09-09)
National lung matrix trial (NLMT)
The largest stratified medicine dataset of non-small cell lung cancer patients indicates further molecular stratifications could benefit from targeted therapies, according to research presented today at the IASLC 2019 World Conference on Lung Cancer, hosted by the International Association for the Study of Lung Cancer. (2019-09-09)
Scottish study shows that autoantibody test followed by CT imaging may reduce lung cancer mortality
A combination of the EarlyCDT-Lung Test followed by CT imaging in Scottish patients at risk for lung cancer resulted in a significant decrease in late stage diagnosis of lung cancer and may decrease lung cancer specific mortality, according to research presented at IASLC 2019 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer (IASLC). (2019-09-09)
Video assisted lung surgery reduces complications and hospital stays compared to open surgery
Video-assisted thoracic surgery is associated with lower in-hospital complications and shorter length of stay compared with open surgery among British patients who were diagnosed at an early stage of lung cancer, according to research presented today the IASLC 2019 World Conference on Lung Cancer, hosted by the International Association for the Study of Lung Cancer. (2019-09-09)
Durvalumab combined with chemotherapy improves overall survival in patients with lung cancer
Adding immunotherapy in the form of durvalumab to chemotherapy improves overall survival in patients with extensive-stage small cell lung cancer, according to research presented today at the IASLC 2019 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer (IASLC). (2019-09-09)
Major gaps exist in patient understanding of genomic test results, Lung-MAP study shows
A majority of cancer patients don't understand key aspects of the genomic test results they receive as participants in biomarker-driven clinical trials, according to a first-of-its-kind pilot study conducted under the Lung Cancer Master Protocol (Lung-MAP). (2019-09-09)
Blood test shows promise to aid better detection of lung cancer
Lung cancer can be spotted earlier and diagnosed more precisely with the help of a blood test. (2019-09-09)
Lung cancer screening model favored in Europe detects more cancers than 1 preferred in the US
Researchers reported today that a prospective trial comparing 2 screening methods for at-risk lung cancer patients found that a model used by Canadian, Australian and European public health organizations detected more cancers than the screening model used by the United States Preventive Services Task Force (USPSTF). (2019-09-09)
BioMILD trial demonstrates lung cancer screening using MicroRNA blood test enhances prevention
Lung cancer screening efforts have accelerated in the last decade, with researchers showing that low dose CT screening is effective in reducing lung cancer mortality. (2019-09-09)
New KEYNOTE 021 data shows no association with tumor mutational burden
Researchers had previously reported data from the KEYNOTE 021 trial that showed antitumor activity for pembrolizumab plus platinum-based chemotherapy in untreated advanced nonsquamous non-small cell lung cancer patients. (2019-09-08)
Nivolumab combined with ipilimumab safe as first-line therapy for lung cancer patients
Combining the PD-1 immune check point inhibitor nivolumab with the monoclonal antibody ipilimumab showed a consistent safety profile in special populations with advanced non-small cell lung cancer (NSCLC), according to research presented today by at the IASLC 2019 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer. (2019-09-08)
Phase 1 study shows novel KRAS inhibitor well tolerated by patients with adenocarcinoma and non-small cell lung cancer
A clinical trial testing the toxicity of a KRAS inhibitor demonstrated early promising antitumor activity and few adverse side effects in patients with advanced non-small cell lung cancer harboring KRAS G12C mutation, according to research presented today at the IASLC 2019 World Conference on Lung Cancer, hosted by the International Association for the Study of Lung Cancer. (2019-09-08)
Keynote 189: Tumor mutational burden not significantly associated with efficacy of pembrolizumab
Tumor mutational burden was not significantly associated with efficacy of pembrolizumab plus chemotherapy or placebo plus chemotherapy as first-line therapy for metastatic nonsquamous non-small cell lung cancer, according to research reported today by Dr. (2019-09-08)
BioMILD trial demonstrates lung cancer screening using microrna blood test enhance prevention effort
Lung cancer screening efforts have accelerated in the last decade, with researchers showing that low dose CT screening is effective in reducing lung cancer mortality. (2019-09-08)
Mutations associated with sensitivity or resistance to immunotherapy in mNSCLC
The relationship between gene alterations and response to anti-PD-L1 with and without anti-CTLA-4 are not well characterized. (2019-09-08)
Analysis from the MYSTIC Trial
The relationship between gene alterations and response to An update from the Phase III MYSTIC study showed poorer outcomes across treatment arms in patients with metastatic non-small cell lung cancer and mutations in STK11 or KEAP1 genes compared with those without the corresponding mutations. (2019-09-08)
Tobacco cessation after cancer diagnosis: Declaration from the IASLC
The International Association for the Study of Lung Cancer today used the platform of its largest international meeting to call attention to the importance of tobacco cessation after cancer diagnosis, and urged all physicians to screen cancer patients for tobacco use and recommend tobacco cessation. (2019-09-07)
Natural 'breakdown' of chemicals may guard against lung damage in 9/11 first responders
The presence of chemicals made as the body breaks down fats, proteins, and carbohydrates can predict whether Sept. (2019-09-03)
Self-monitoring solution in mobile app can help uncontrolled asthma
A study by researchers at Karolinska Institutet shows that a treatment adjustment algorithm based on lung function and symptoms in a mobile phone can be an efficient tool in managing uncontrolled asthma. (2019-09-03)
Identification of new populations of immune cells in the lungs
In an article published in Nature Communications, the Immunophysiology Laboratory of the GIGA Institute, headed by Prof. (2019-09-03)
Cancer cells 'corrupt' their healthy neighbors
The healthy cells immediately surrounding a tumor become more stem cell-like and support cancer growth, reveals a new study published in Nature. (2019-08-28)
Little-used drug combination may extend the lives of lung transplant patients
Median survival after lung transplant is less than six years. (2019-08-28)
Gene mutations coordinate to drive malignancy in lung cancer
Scientists have shown exactly how mutations in two different genes coordinate to drive the development of malignant lung tumors, according to a new report in the open-access journal eLife. (2019-08-27)
New drug combination shows promising activity in non-small cell lung cancer patients
Patients with non-small cell lung cancer (NSCLC) now have more improved treatment options compared to standard of care with the addition of several new agents called immune-checkpoint inhibitors (ICI). (2019-08-27)
Heavy drinking and HIV don't mix
Heavy alcohol consumption (3 drinks or more/day for women and 4 drinks or more/day for men) is linked to alterations in immune function among people with HIV. (2019-08-22)
E-cigs can trigger same lung changes seen in smokers, emphysema
In a study published in the American Journal of Respiratory and Critical Care Medicine, the UNC scientists found that the lungs of vapers -- like the lungs of smokers -- have elevated levels of protease enzymes, a condition known to cause emphysema in smokers. (2019-08-22)
How our genes and environment influence BMI and height
Environmental conditions influence our body mass index (BMI) by increasing or decreasing the effect of inherited genetic variations, University of Queensland researchers have discovered. (2019-08-22)
Researchers discover cause of asthmatic lung spasms
Researchers at Rutgers and other institutions have discovered how muscle contraction (bronchospasm) in the airway, which cause breathing difficulty in people with asthma, occur by creating a microdevice that mimics the behavior of the human airways. (2019-08-22)
Lung cell transplant boosts healing after the flu in mice
A serious case of the flu can cause lasting damage to the lungs. (2019-08-20)
Vaping impairs vascular function
Inhaling a vaporized liquid solution through an e-cigarette, otherwise known as vaping, immediately impacts vascular function even when the solution does not include nicotine, according to the results of a new study. (2019-08-20)
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