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Physicians don't adequately monitor patients' medication adherence
Physicians don't do as much as they could to ensure that patients adhere to their medication regimens, highlighting the need to develop better methods for doctors to identify non-adherence and to change that behavior. (2012-07-16)

Annals of Internal Medicine tip sheet for July 3, 2012, issue
This release contains information about articles being published in the July 3 issue of Annals of Internal Medicine. (2012-07-02)

Provinces could save millions in prescription drug costs, new research finds
Taxpayers could save millions of dollars if hospitals and provincial governments harmonized their prescription drug plans, new research suggests. (2012-06-26)

Experimental drug helps diabetes patients lose weight
An experimental drug helped significantly more overweight patients with diabetes shed pounds, compared with placebo, a new study finds. The results will be presented Saturday at the Endocrine Society's 94th Annual Meeting in Houston. (2012-06-25)

Modified bariatric surgery provides remission of Type 2 diabetes
Type 2 diabetes often reverses after modified weight loss surgery, especially when the duration of diabetes is less than 10 years, a new study finds. The results will be presented Tuesday at the Endocrine Society's 94th Annual Meeting in Houston. (2012-06-25)

Common diabetes drugs associated with increased risk of death
Compared to another popular drug, three widely used diabetes medications are associated with a greater risk of death, a large new analysis finds. The results will be presented Sunday at the Endocrine Society's 94th Annual Meeting in Houston. (2012-06-24)

Physical fitness may improve survival among diabetes patients with heart dysfunction
Being physically fit may improve survival rates among diabetes patients with a particular type of heart abnormality, a new study determines. The results will be presented Sunday at the Endocrine Society's 94th Annual Meeting in Houston. (2012-06-24)

Experimental insulin drug prevents low blood sugar
An experimental insulin drug prevented low blood sugar among diabetic patients more often than a popular drug on the market, a new study finds. The results will be presented Sunday at the Endocrine Society's 94th Annual Meeting in Houston. (2012-06-24)

Changes needed for oft-ignored prescription warning labels
Each year, an estimated four million Americans experience adverse reactions to prescription medications. Many of these reactions, ranging from mild rashes and drowsiness to hospitalization and death, could be avoided if warning labels were more effective, according to a Michigan State University study. (2012-06-15)

Nanomedicines promise fewer side effects in treating cancer
A new generation of cancer treatments based on nanotechnology is making its way out of the laboratory and into the clinic with the promise of targeting cancer cells while steering clear of healthy tissue, according to the current edition of Chemical & Engineering News (C&EN). C&EN is the weekly newsmagazine of the American Chemical Society, the world's largest scientific society. (2012-06-06)

Acetaminophen overdoses in children can be life-threatening but are avoidable
Acetaminophen, a widely available over-the-counter medication, can cause liver toxicity in children if doses are exceeded, and more public education is needed to warn of potential adverse effects, states an article published in CMAJ. (2012-06-04)

Minnesota, Mayo Clinic join to advise primary care doctors on pediatric mental health
The Minnesota Department of Human Services has entered into a two-year contract with Mayo Clinic to provide expert guidance to pediatricians and other primary care providers who prescribe psychotropic medications for children. The new service is referred to as (2012-06-04)

Dementia care model that reduces hospitalizations successfully translated into practice
Translating research into practice, a model of dementia care developed by Regenstrief Institute and Indiana University researcher-clinicians that significantly reduces emergency department visits and hospitalizations, and encourages use of medications that are not harmful to older brains has now been used to treat over 1,000 patients. (2012-05-31)

Commonly used painkillers may protect against skin cancer
A new study suggests that aspirin and other similar painkillers may help protect against skin cancer. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the findings indicate that skin cancer prevention may be added to the benefits of these commonly used medications. (2012-05-29)

Common acne medication doubles risk of eye infection
Dr. Gabriel Chodick of Tel Aviv University says that acne patients who take oral medications like Accutane double their risk of developing an eye infection compared to those who do not. He says that the use of inexpensive artificial tears or eyedrops, which are available over-the-counter at the local pharmacy, can minimize this eye damage. (2012-05-23)

Asthma medication linked with arrhythmias in children, young adults
Use of inhaled anticholinergics (IACs) has been associated with an increased risk of potentially dangerous heart arrhythmias among young asthma patients, according to a study conducted by researchers at the University of Illinois at Chicago. The medications are commonly used to help control asthma flare-ups, and recent studies have shown that they may be an effective treatment option for routine asthma management. (2012-05-22)

Good Samaritan Hospital, the first and only Dayton hospital, to offer bronchial thermoplasty
Good Samaritan Hospital announced today that it is now offering an innovative procedure called bronchial thermoplasty for the treatment of severe asthma. Good Samaritan Hospital is the first and only hospital in the Dayton region to offer this non-drug procedure. (2012-05-17)

Reducing off-label use of antipsychotic medications may save money
Reducing the non-FDA-approved use of antipsychotic drugs may be a way to save money while having little effect on patient care, according to a Penn State College of Medicine study. (2012-05-15)

Blood pressure drugs don't protect against colorectal cancer
A new study has found that, contrary to current thinking, taking beta blockers that treat high blood pressure does not decrease a person's risk of developing colorectal cancer. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study also revealed that even long-term use or subtypes of beta blockers showed no reduction of colorectal cancer risk. (2012-05-14)

Study: No difference in results by race with standard heart failure treatment
A traditional treatment for heart failure appears to be equally protective in preventing death or hospitalization among African-American patients, as compared to white patients, according to a study at Henry Ford Hospital in Detroit. (2012-05-09)

Blood pressure drugs linked with lower PTSD symptoms
Traumatized people who take a class of common blood pressure medications tend to have less severe post-traumatic stress symptoms, researchers have found. The finding suggests that ACE (angiotensin converting enzyme) inhibitors or ARBs (angiotensin receptor blockers) could be valuable tools for treating or preventing post-traumatic stress disorder. (2012-05-01)

New research expands understanding of psychoactive medication use among children in foster care
New research looked at 686,000 foster-care children enrolled in Medicaid annually in 48 states from 2002-2007. The percentage of children in foster care taking antipsychotics -- a class of psychoactive drugs associated with serious side effects for children -- continued to climb in the last decade. At the same time, a slight decline was seen in the use of other psychoactive medications, including the percentage of children receiving three or more classes of these medications at once. (2012-04-30)

Progress against HIV thwarted by patients' unmet needs
In a groundbreaking study published last year, scientists reported that effective treatment with HIV medications not only restores health and prolongs life in many HIV-infected patients, but also curtails transmission to sexual partners up to ninety-seven percent. However, a new study by UCSF scientists shows that lack of basic living needs severely undercuts these advances in impoverished men. (2012-04-26)

Canadian study suggests off-label prescribing of medications is common
A study evaluating off-label prescribing of medications in a primary care network in Canada suggests the practice is common, although it varies by medication, patient and physician characteristics, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication. The report is part of the journal's Health Care Reform series. (2012-04-16)

Meds ease depression in Parkinson's patients without worsening other symptoms
Today's anti-depressant medications can ease depression in Parkinson's patients without worsening other symptoms of the disease, according to a study published online in Neurology. About half of Parkinson's patients struggle with depression, which doctors say is the top factor negatively affecting the quality of life for people with the disease. (2012-04-11)

Researchers identify successful strategies for weight loss in the obese
In a new study published in the American Journal of Preventive Medicine, researchers from Harvard Medical School and Beth Israel Deaconess Medical Center in Boston have found in a nationally representative sample that obese dieters who said they ate less fat, exercised more, and used prescription weight loss medications were more likely to lose weight. Diet foods and products, nonprescription diet pills, and popular diets were less successful, according to the researchers. (2012-04-10)

Pulse pressure elevation could presage cerebrovascular disease in Alzheimer's patients
Researchers at the University of California, San Diego and Veterans Affairs San Diego Healthcare System have shown that elevated pulse pressure may increase the risk of cerebrovascular disease in older adults with Alzheimer's disease. (2012-04-06)

Warfarin related to low rate of residual stroke in patients with atrial fibrillation
A review of clinical trials comparing warfarin with other medications for stroke prevention suggests that warfarin was associated with a low risk of stroke or non-central nervous system embolism in patients with nonvalvular atrial fibrillation (rapid, irregular heart beat), according to a study published online first by Archives of Internal Medicine, one of the JAMA/Archives journals. (2012-03-26)

Cleveland Clinic study shows bariatric surgery improves, reverses diabetes
Overweight, diabetic patients who underwent bariatric surgery achieved significant improvement or remission of their diabetes, according to new research from Cleveland Clinic. In a randomized, controlled trial, some weight loss surgery patients achieved normal blood sugar levels without use of any diabetes medications. In others, the need for insulin to control blood sugar was eliminated. (2012-03-26)

Telemedicine improves medication management, patient care
Internet-based telemedicine systems appear to lead to more appropriate and effective pharmacotherapy, better blood pressure control and an overall reduction in cardiovascular risk compared to conventional, periodic office visits, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session. The Scientific Session, the premier cardiovascular medical meeting, brings cardiovascular professionals together to further advances in the field. (2012-03-24)

Antidepressant use during pregnancy and high blood pressure
Use of selective serotonin re-uptake inhibitor antidepressants during pregnancy appears to be linked with increased risk of pregnancy induced high blood pressure (hypertension), but a causal link has not been established. (2012-03-21)

Study: Low bone density medications may have protective effect on endometrial cancer
Medications like Fosamax may protect some women from the most common type of uterine cancer, according to a study at Henry Ford Hospital. (2012-03-21)

Pain relievers could be spiking your blood pressure
Both doctors and patients should be aware that many common over-the-counter and prescription medications can be the underlying cause of hypertension, says Prof. Ehud Grossman of Tel Aviv University. He warns that while many of the chemicals in these drugs can raise blood pressure, both patients and doctors remain dangerously uninformed. (2012-03-20)

Diagnosis of ADHD on the rise
The number of American children leaving doctors' offices with an attention deficit hyperactivity disorder diagnosis has risen 66 percent in 10 years, according to a new Northwestern Medicine study. (2012-03-19)

Combined therapy of acne medications offers new treatment option for patients
A combined therapy of common acne medications was shown to be a potent regimen for treating patients with severe facial acne, according to two published studies involving Henry Ford Hospital. The companion studies found that a therapy of the topical Epiduo Gel containing adapalene and benzoyl peroxide and the antibiotic doxycycline proved more effective at reducing acne lesions compared to other treatment regimens. (2012-03-14)

Drug coverage of Medicare beneficiaries with kidney failure -- some surprising findings
The majority of Medicare beneficiaries with kidney failure participate in Medicare's Part D prescription drug coverage program, and most of these receive a low-income subsidy from the program, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology. (2012-03-08)

Canadian researchers identify a new way to image bleeding in arteries of the brain
New research from the University of Calgary's Hotchkiss Brain Institute shows that by using a CT scan, doctors can predict which patients are at risk of continued bleeding in the brain after a stroke. This vital information will allow doctors to utilize the most powerful blood clotting medications for those with the highest risk. (2012-03-07)

New research characterizes glaucoma as neurologic disorder rather than eye disease
A new paradigm to explain glaucoma is generating brain-based treatment advances. A review article in Ophthalmology, the journal of the American Academy of Ophthalmology, says that some top researchers no longer consider glaucoma solely an eye disease, but rather a neurologic disorder with some similarities to Parkinson disease and Alzheimer's. The review, supported by Bascom Palmer Eye Institute and Interdisciplinary Stem Cell Institute, describes treatment advances now in human trials or scheduled to begin trials soon. (2012-03-06)

Hyperactivity: Increased prevalence of children with ADHD and the use of stimulants
A new study from the University of Montreal shows an increase in prevalence of Canadian children diagnosed with attention-deficit hyperactivity disorder and in the use of medications associated with ADHD in school-age children. (2012-03-05)

Stress making your blood pressure rise? Blame your immune system
If stress is giving you high blood pressure, blame the immune system. T cells, helpful for fighting infections, are also necessary for mice to show an increase in blood pressure after a period of psychological stress, scientists have found. The findings suggest the effects of chronic stress on cardiovascular health may be a side effect of having an immune system that can defend us from infection. There also are potential implications for treating both high blood pressure and anxiety disorders. (2012-03-02)

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