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Current Melanoma News and Events, Melanoma News Articles.
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Genomic testing of a single patient reveals a gene commonly mutated in pediatric melanoma
Comprehensive clinical genomic testing of an adolescent patient, including whole genome sequencing, helped researchers identify mutations in a single gene that drive the most common childhood melanoma. (2019-03-04)
Artificial intelligence could predict spread of melanoma
The BGU/ UTSW group demonstrated that their representation of the functional state of individual cells can predict the likelihood that a stage III melanoma, with malignancies limited to the lymphatic system, will progress to stage IV, in which the cancer has spread from the principal area to the rest of the patient's body. (2019-02-26)
A single dose of a PD-1 inhibitor before surgery predicts outcomes in melanoma patients
A single dose of a PD-1 inhibitor before surgery for melanoma can put patients in remission. (2019-02-25)
Study finds melanoma brain metastases are immunosuppressive with treatment-resistant metabolism
Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites. (2019-02-20)
Researchers develop new one-two punch against melanoma in mouse model
Study shows new forms of an older anti-cancer agent appear to enhance the immune system's ability to fight melanoma in mice. (2019-02-19)
Smoking may limit body's ability to fight dangerous form of skin cancer
Melanoma patients with a history of smoking cigarettes are 40 percent less likely to survive their skin cancer than people who have never smoked, according to a new report funded by Cancer Research UK. (2019-02-17)
Combo T cell and targeted therapy strategy for resistant melanoma with BRAF mutation
Collaborative research by The Wistar Institute and Moffitt Cancer Center has demonstrated that BRAF targeted therapies render resistant melanoma more sensitive to the attack of killer T cells. (2019-02-14)
Cancer comparison across species highlights new drug targets
Cancer genes in mucosal melanoma, a rare and poorly understood subtype of melanoma, have been compared in humans, dogs and horses for the first time by scientists at the Wellcome Sanger Institute and their collaborators. (2019-02-12)
Cross-species cancer comparison uncovers new drug targets, study reveals
Mucosal melanoma arises in non-skin locations such as sinuses, nasal passages and mouth. (2019-02-12)
Nullifying protein YTHDF1 enhances anti-tumor response
Identifying molecular pathways that boost the immune response to tumor neoantigens opens up new ways to develop and amplify cancer immunotherapy. (2019-02-06)
No overall increased risk of cancer in children born after fertility treatment
Children born after assisted reproductive technology (ART) do not appear to be at greater risk of developing cancer than other children, according to the first study to look at the long-term cancer risk in ART children compared to those in the general population or who were naturally conceived by subfertile women. (2019-02-03)
Researchers discover method to 'turn off' mutated melanoma
Melanoma is the deadliest form of skin cancer and notorious for its resistance to conventional chemotherapy. (2019-01-31)
Skin cancer can spread in mice by hijacking the immune system
Scientists have uncovered molecules released by invasive skin cancer that reprogram healthy immune cells to help the cancer to spread. (2019-01-31)
Genetically modified virus injection into tumor can treat metastatic melanoma
Results published in the Journal of the American College of Surgeons show sustained effectiveness of disease response and favorable side effect profile. (2019-01-25)
Heating up cold tumors
A Ludwig Cancer Research study has uncovered a cellular mechanism by which melanomas that fail to respond to checkpoint blockade may be made susceptible to such immunotherapies. (2019-01-22)
New nanoparticle targets tumor-infiltrating immune cells, flips switch
A team of Vanderbilt University bioengineers today announced a major breakthrough in penetrating the cells inside tumors and flipping on a switch that tells them to start fighting. (2019-01-21)
New PET probe could improve detection of primary and metastatic melanoma
A new nuclear medicine method for detecting malignant melanoma, one of the most aggressive skin cancers, has been successfully tested for the first time in humans and could improve detection of both primary and metastatic melanoma. (2019-01-16)
States with fewer melanoma diagnoses have higher death rates
Researchers at University of Utah Health conducted a state-by-state analysis to understand the geographic disparities for patients diagnosed with melanoma. (2019-01-15)
Hindering melanoma metastasis with an FDA-approved drug
A drug approved by the FDA 65 years ago for blood pressure control may aid in preventing cancer from spreading to distant organs. (2019-01-14)
VISTA checkpoint implicated in pancreatic cancer immunotherapy resistance
Researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety of other cancers. (2019-01-11)
Melanoma: dabrafenib and trametinib have added benefit
This combination showed advantages in survival and recurrence. An added benefit was not proven for another combination used in advanced disease. (2019-01-08)
Researchers reveal new mechanism to 'activate' the immune system against cancer
A new mechanism for activating the immune system against cancer cells allows immune cells to detect and destroy cancer cells better than before, and most effectively in lung cancer and melanoma. (2019-01-04)
'Christmas berry' plant compound could fight Uveal melanoma
A molecule derived from a type of primrose could prove to be a potent inhibitor of metastatic growth for a rare and aggressive cancer. (2019-01-03)
Researchers from the CNIO and the Hospital 12 de Octubre make sense out of the chaos of melanoma
The study has discovered that numerous processes involved in the metastasis of melanoma, which were thought to be independent from each other, have a global coordinator: the p62 protein. (2018-12-20)
Two ways cancer resists treatment are actually connected, with one activating the other
Researcher shows the two most common means of resistance to BRAF and MEK inhibitors are actually connected processes and can be targeted by other therapies. (2018-12-18)
Combining three treatment strategies may significantly improve melanoma treatment
A study by a team led by a Massachusetts General Hospital investigator finds evidence that combining three advanced treatment strategies for malignant melanoma -- molecular targeted therapy, immune checkpoint blockade and the use of tumor-targeting viruses -- may markedly improve outcomes. (2018-12-12)
The naked eye alone is not enough to ensure the accurate diagnosis of skin cancer, say experts
The visual inspection of a suspicious skin lesion using the naked eye alone is not enough to ensure the accurate diagnosis of skin cancer, a group of experts have concluded. (2018-12-06)
Wireless, battery-free sensors monitor skin exposure to solar radiation
Researchers have created wireless, battery-free sensors that can monitor exposure to solar radiation in real time. (2018-12-05)
New drug combination could be more effective against melanoma
A new study from MIT suggests that combining kinase inhibitors with experimental drugs known as ribonucleases could lead to better results. (2018-12-03)
Researchers advance role of circulating tumor DNA to detect early melanoma growth
Researchers at the Johns Hopkins Kimmel Cancer Center say they have added to evidence that measuring and monitoring tumor DNA that naturally circulates in the blood of melanoma patients can not only reliably help reveal the early stages of cancer growth and spread but also uncover new treatment options that tumor genetic analysis alone may not. (2018-11-26)
Targeting MC1R in metastatic melanoma
University of Colorado Cancer Center study describes a molecule that seeks out melanoma cells, for imaging and potentially for therapy. (2018-11-26)
Cutting the legs off cancer
Melanoma skin cancer tumors grow larger and are more likely to metastasize due to interactions between a pair of molecules, according to experiments in mice and human cells. (2018-11-20)
Genomics provide hope for those with 'one in a million' cancer diagnosis
New research has shown that many people with rare cancers can benefit from genomic profiling. (2018-11-13)
How melanoma evades targeted therapies
New research shows how metastatic melanoma becomes resistant to a common class of targeted therapy. (2018-11-06)
Team studying rare disorder discovers novel way to target melanoma
While studying a rare genetic disorder called NGLY1 deficiency, UNT Health Science Center researchers discovered a new targeted treatment for combating melanoma, a skin cancer that kills about 9,000 people in the United States each year. (2018-11-05)
Melanoma death rates are rising in men but static or falling in women
The rate of men dying from malignant melanoma has risen in populations around the world, while in some countries the rates are steady or falling for women, according to research presented at the 2018 NCRI Cancer Conference. (2018-11-04)
Specific CD8 T cell states may indicate response to immune checkpoint therapy for melanoma
A multi-institutional research team, led by investigators at Massachusetts General Hospital and the Broad Institute of MIT and Harvard, has identified specific states of cytotoxic CD8 T cells associated with patient response to checkpoint immunotherapy for melanoma. (2018-11-01)
Fishing for new leads in a rare melanoma
Many cancers arise from a double hit: activation of a tumor-promoting gene plus loss of a tumor suppressor gene. (2018-11-01)
Cytokine levels could predict immunotherapy problems
Researchers at UT Southwestern have identified blood-based biomarkers that may help identify those patients at greatest risk of developing autoimmune side effects from the treatment. (2018-10-31)
Droplet Digital PCR enables precise detection and quantification of a promoter mutation prevalent in many cancer types
Research from NYU Langone Medical Center and its Perlmutter Cancer Center along with Bio-Rad's Digital Biology Group demonstrates how two new ddPCR-based assays can specifically detect and quantify mutations linked to many cancer types. (2018-10-30)
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