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Current Metabolism News and Events, Metabolism News Articles.
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Yale researchers help restore hormonal balance disrupted in metabolic diseases
Many health problems in the developed world stem from the disruption of a delicate metabolic balance between glucose production and energy utilization in the liver. (2020-03-04)
Artificial sweeteners combined with carbs may be more harmful than those sweeteners alone
The influence of artificial sweeteners on the brain and ultimately metabolism has been hotly debated in recent years. (2020-03-03)
Yale study may help resolve bitter debate over low-cal sweeteners
A new Yale study showed that people who periodically drank beverages with the low-calorie sweetener sucralose, which is found in low-cal soft drinks, candy, breakfast bars, and other products, did experience problematic metabolic and neural responses -- but only when a carbohydrate in the form of a tasteless sugar was added to the drink. (2020-03-03)
Alzheimer's: Can an amino acid help to restore memories?
Scientists at the Laboratoire des Maladies Neurodégénératives (CNRS/CEA/Université Paris-Saclay) and the Neurocentre Magendie (INSERM/Université de Bordeaux) have just shown that a metabolic pathway plays a determining role in Alzheimer's disease's memory problems. (2020-03-03)
IU scientists study link between energy levels, spinal cord injury
A team of researchers from Indiana University School of Medicine, in collaboration with the National Institute of Neurological Disorders and Stroke, have investigated how boosting energy levels within damaged nerve fibers or axons may represent a novel therapeutic direction for axonal regeneration and functional recovery. (2020-03-03)
Hydrogen energy at the root of life
A team of international researchers in Germany, France and Japan is making progress on answering the question of the origin of life. (2020-03-02)
Oncotarget | SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism
Oncotarget Volume 11 Issue 8 reported that while it is known that cancer cells require one-carbon and FAD-dependent mitochondrial metabolism to sustain cell proliferation, the role of SLC25A32 in cancer cell growth remains unexplored. (2020-02-28)
Cells carrying Parkinson's mutation could lead to new model for studying disease
Parkinson's disease researchers have used gene-editing tools to introduce the disorder's most common genetic mutation into marmoset monkey stem cells and to successfully tamp down cellular chemistry that often goes awry in Parkinson's patients. (2020-02-27)
Sex-specific traits of the immune system explain men's susceptibility to obesity
Melbourne researchers have uncovered important differences between the male and female immune system which may explain why men are more susceptible to obesity and metabolism-related associated diseases, such as heart disease, stroke and diabetes. (2020-02-26)
Antioxidant precursor molecule could improve brain function in patients with MS
The naturally occurring molecule N-acetylcysteine (NAC) shows benefit in a clinical trial for multiple sclerosis. (2020-02-26)
Reduced stress changes profile of various lipid compounds
Reduced stress is linked to changes in the profile of plasma metabolites, a new study from the University of Eastern Finland shows. (2020-02-25)
Cellular metabolism regulates the fate decision between pathogenic and regulatory T cells
Preclinical research shows a pivotal role for cellular metabolism to regulate the fate decision of naïve CD4 T cells as they differentiate into either destructive Th17 cells that mediate chronic inflammation or regulatory Treg T cells, a decision that occurs very early in the activation of CD4 T cells. (2020-02-25)
People who eat a big breakfast may burn twice as many calories
Eating a big breakfast rather than a large dinner may prevent obesity and high blood sugar, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2020-02-19)
Vitamin C may shorten ventilation in critically ill patients
Vitamin C administration shortened the duration of mechanical ventilation in critical care patients, but the effect depended on the severity of illness. (2020-02-14)
Heart muscle cells change their energy source during heart regeneration
Researchers from the Hubrecht Institute (KNAW) have found that the muscle cells in the heart of zebrafish change their metabolism during heart regeneration. (2020-02-04)
Aerobic exercise training linked to enhanced brain function
Amsterdam, NL, February 3, 2020 - Individuals at risk for Alzheimer's disease (AD) because of family history or genetic predisposition who engaged in six months of aerobic exercise training improved their brain glucose metabolism and higher-order thinking abilities (e.g., planning and mental flexibility) called executive function; these improvements occurred in conjunction with increased cardiorespiratory fitness. (2020-02-03)
HKUST researchers find that regulating lipid metabolism in neurons helps axon regeneration
Regenerative medicine is the study of repairing tissue and organ function that is lost due to injury, aging, or disease. (2020-01-30)
Disease-aggravating mutation found in a mouse model of neonatal mitochondrial disease
The new mitochondrial DNA (mtDNA) variant drastically speeds up the disease progression in a mouse model of GRACILE syndrome. (2020-01-29)
Key to beating colorectal cancer hiding in plain sight?
Colorectal cancer, one of the most common cancers in the developed world, is intrinsically resistant to many drug therapies. (2020-01-28)
Keto diet works best in small doses, Yale researchers find
A ketogenic diet -- which provides 99% of calories from fat and only 1% from carbohydrates -- produces health benefits in the short term, but negative effects after about a week, Yale researchers found in a study of mice. (2020-01-27)
'Ancient' cellular discovery key to new cancer therapies
Australian researchers have uncovered a metabolic system which could lead to new strategies for therapeutic cancer treatment. (2020-01-21)
Dresden biologists make living sperm glow
By applying a novel method, biologists at TU Dresden have successfully analysed the metabolism of intact tissues of the fruit fly using a label-free microscopy technique. (2020-01-15)
A new model of metabolism draws from thermodynamics and 'omics'
Scientists at EPFL have developed an algorithm that can model biochemical reactions from metabolism down to RNA synthesis with unprecedented accuracy. (2020-01-13)
New mechanism may safely prevent and reverse obesity
Researchers at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center have discovered that a receptor found in almost all cells plays a big role in the body's metabolism. (2020-01-13)
Study reveals long-term benefits of weight loss surgery in adults with obesity and diabetes
Researchers recently conducted the largest study to date, which is published in Diabetes/Metabolism Research and Reviews, to evaluate the effectiveness of weight loss surgery in a Chinese population of individuals with obesity and type 2 diabetes. (2020-01-08)
Targeting cholesterol metabolism in macrophages to eliminate viral infection
A new study published in Immunity now provides important new information. (2019-12-27)
New insights into the earliest events of seed germination
Plant seeds can store their energy in a dry state for years, only to suddenly release it and germinate. (2019-12-27)
Evolution: Revelatory relationship
A new study of the ecology of an enigmatic group of novel unicellular organisms by scientists from Ludwig-Maximilians-Universitaet (LMU) in Munich supports the idea hydrogen played an important role in the evolution of Eukaryota, the first nucleated cells. (2019-12-27)
Newly developed mathematical model could be used to predict cancer drug side effects
A research team at Kobe University Hospital have further illuminated the likelihood of cancer drug side effects that can occur due to genetic mutations in the drug-metabolizing enzyme. (2019-12-20)
Overspill of fat shown to cause Type 2 Diabetes
For the first time, scientists have been able to observe people developing Type 2 diabetes - and confirmed that fat over-spills from the liver into the pancreas, triggering the chronic condition. (2019-12-20)
Longevity protein SIRT6 also protects against fatty liver and fatty liver disease
SIRT6 regulates fat metabolism by activating another protein called peroxisome proliferator-activated receptor alpha (PPAR-alpha). (2019-12-20)
Glutamine may decrease obesity-linked inflammation
Glutamine could help people with obesity reduce inflammation of fat tissue and reduce fat mass, according to a new study at Karolinska Institutet in Sweden and the University of Oxford in the U.K. (2019-12-19)
A new role for a triple-negative breast cancer target
A team led by Rumela Chakrabarti of the University of Pennsylvania has made new discoveries into how a key protein involved in triple-negative breast cancer functions in puberty. (2019-12-19)
How immune cells switch to attack mode
Macrophages have 2 faces: In healthy tissue, they perform important tasks and support their environment. (2019-12-17)
Perinatal exposure to flame retardant alters epigenome, predisposing metabolic disease
A UMass Amherst study showed that environmentally relevant exposure to polybrominated diphenyl ether (PBDE), a brominated flame retardant, through the umbilical cord and breast milk permanently changed liver metabolism in rats. (2019-12-13)
Russian scientists studied the effect of selenium on the properties of basil
Today many agricultural plants are grown using hydroponics, i.e. in artificial soilless environments. (2019-12-12)
Study finds differences in energy use by immune cells in ME/CFS
New findings published in the Journal of Clinical Investigation suggest that specific immune T cells from people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) show disruptions in the way they produce energy. (2019-12-12)
Increasing food intake by swapping mitochondrial genomes
To uncover the relationship between variation in genes and phenotypic diversity, geneticists use a set of fully sequenced fruit-fly genomes. (2019-12-09)
Secret behind diabetes drug's benefits revealed
Researchers went into this study with the idea that metformin might communicate with other tissues in the body by causing the secretion of a protein from the liver. (2019-12-09)
Pilot study finds time-restricted eating has benefits for people at risk for diabetes
In a study publishing Dec. 5 in the journal Cell Metabolism, researchers for the first time looked at the effects of TRE in people who had been diagnosed with metabolic syndrome and therefore were at a higher risk of diabetes, heart disease, and stroke. (2019-12-05)
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