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Current Microtubule News and Events, Microtubule News Articles.
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Visualizing 'unfurling' microtubule growth
Living cells depend absolutely on microtubules that form a scaffolding for moving materials inside the cell. (2018-11-13)
Keeping our cells stable: A closer look at microtubules
Microtubules help to regulate cell structure throughout our bodies. A group of Japanese researchers have used cryo-electron microscopy to shed light on how a certain protein keeps microtubules stable, and regulates microtubule-based transport within cells. (2018-10-01)
Regulation of cell orientation and shape for tissue morphogenesis
A collaborative research group led by Kumamoto University has developed a new control system for regulating the morphology and orientation of cells that constitute animal tissues. (2018-07-24)
Solved protein puzzle opens door to new design for cancer drugs
Researchers at have solved a longstanding puzzle concerning the design of molecular motors, paving the way toward new cancer therapies. (2018-07-12)
Parental chromosomes kept apart during embryo's first division
It was long thought that during an embryo's first cell division, one spindle is responsible for segregating the embryo's chromosomes into two cells. (2018-07-12)
Study: Tau does not stabilize microtubules, challenges approach to treating Alzheimer's
Though it is widely believed that tau protein stabilizes microtubules in neurons of the brain, new research suggests just the opposite: tau lengthens microtubules and keeps them dynamic. (2018-06-28)
New regulator of neuron formation identified
The protein NEK7 regulates neuron formation, as it is required for dendrite growth and branching, as well as the formation and shaping of dendritic spines. (2018-06-27)
New insights into pruning
When an organism develops, non-specific connections between nerve cells degenerate. (2018-06-26)
UEA research could help fine-tune cancer treatment
Cancer therapies that cut off blood supply to a tumour could be more effective in combination with existing chemotherapeutic drugs -- according to new research from the University of East Anglia. (2018-05-25)
Tau mutations may increase cancer risk
Mutations to the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer, according to results published in Cancer Research, a journal of the American Association for Cancer Research. (2018-05-24)
Petry finds missing ingredient to spark the fireworks of life
Using a novel imaging technique, the Petry Lab demonstrates that XMAP215, a protein known to help microtubules grow faster and longer, is necessary to nucleating microtubules. (2018-05-16)
Scientists develop method to tweak tiny 'antenna' on cells
Scientists at Johns Hopkins Medicine and the National Tsing Hua University in Taiwan say they have found a fast way to manipulate a cell's cilia, the tiny, fingerlike protrusions that 'feel' and sense their microscopic environment. (2018-05-15)
Key protein in sperm tail assembly identified
A study, published in the Journal of Cell Biology, focuses on the development of the sperm tail, the structure that enables sperm cells to swim and is therefore critical for male fertility. (2018-05-11)
Tau-tolly microtubular!
Researchers at Lawrence Berkeley National Lab (Berkeley Lab) and the University of California, Berkeley have combined cutting-edge cryo-electron microscopy (cryo-EM) with computational molecular modeling to produce a near atomic-resolution model of the interaction between microtubules--crucial components of eukaryotic cell ultrastructure--and microtubule-associated proteins called tau. (2018-05-10)
Cell biology: Dynamics of microtubules
Filamentous polymers called microtubules play vital roles in chromosome segregation and molecular transport. (2018-04-06)
How to build a better railway -- in (almost) every cell in your body
New work from the University of Warwick shows how a microscopic 'railway' system in our cells can optimise its structure to better suit bodies' needs. (2018-03-12)
Evaluation of tau phosphorylation related targets for Alzheimer's disease treatment
InSysBio continues to investigate the mechanisms underlying Alzheimer's disease (AD) using the quantitative systems pharmacology (QSP) modeling approach. (2018-02-27)
New structure discovered in human sperm tails
A highly effective tail is needed in order for a sperm to be able to swim, and for a baby to be conceived. (2018-02-20)
Letting molecular robots swarm like birds
A team of researchers from Hokkaido University and Kansai University has developed DNA-assisted molecular robots that autonomously swarm in response to chemical and physical signals, paving the way for developing future nano-machines. (2018-01-31)
'Simple, but powerful' model reveals mechanisms behind neuron development
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have now uncovered new insights into the regulatory network behind neuron growth. (2017-12-18)
Shedding light on a shadowy organizational hub in cells
Researchers have shed light on the role that a large, enigmatic protein plays in assembling microtubules, paving the way for better cancer treatments. (2017-12-18)
Autism-linked gene stunts developing dendrites
Increased expression of a gene linked to autism spectrum disorders (ASDs) leads to a remodeling of dendrites during brain development, according to a new study conducted in cultured neurons and an ASD mouse model published in JNeurosci. (2017-12-04)
Study suggests a way to stop HIV in its tracks
When HIV-1 infects an immune cell, the virus travels to the nucleus so quickly there's not enough time to set off the cell's alarm system. (2017-11-30)
HKUST researchers reveal new insights into the control of cellular scaffold
HKUST researchers made a breakthrough in understanding how the organization of microtubule cytoskeleton is controlled, revealing an aspect of γTuRC's regulation and demonstrated a previously unknown function of PolD1, a conserved protein that is widely recognized for its role in DNA replication and repair. (2017-11-29)
Women may be more vulnerable to concussions because of 'leaner' nerve fibers, Penn study
Women have smaller, more breakable nerve fibers in the brain compared to men that may make them more susceptible to concussions, suggests a new study from Penn Medicine neuroscientists published online today in the journal Experimental Neurology. (2017-11-27)
Not an illusion: Clever use of mirrors boosts performance of light-sheet microscope
Using a simple 'mirror trick' and not-so-simple computational analysis, scientists affiliated with the Marine Biological Laboratory (MBL) have considerably improved the speed, efficiency, and resolution of a light-sheet microscope, with broad applications for enhanced imaging of live cells and embryos. (2017-11-17)
How to control traffic on cellular highways
Inside cells, protein 'motors' act like trucks on tiny cellular highways to deliver life-sustaining cargoes. (2017-11-09)
Colon cancer: APC protein affects immunity by preventing pre-cancerous inflammation
Adenomatous polyposis coli is a gene whose mutations are associated with a rare, hereditary form of colorectal cancer known as familial adenomatous polyposis. (2017-10-24)
Art advancing science at the nanoscale
Could studying molecular biology ever be as fun as watching a Star Wars movie? (2017-10-18)
How whip-like cell appendages promote bodily fluid flow
Researchers at Nagoya University revealed that a molecule called Daple is essential for the correct orientation and coordinated beating of cilia on the surface of cells lining ventricles in the brain. (2017-08-18)
Molecular microscopy illuminates molecular motor motion
A toddler running sometimes loses footing because both feet come off the ground at the same time. (2017-07-25)
A patent study on the great new hope emerging from marine derived anticancer drugs
Anticancer agents targeting microtubule from marine sources hold great potential in the field of cancer therapeutics and are gradually advancing in the clinical setup. (2017-06-21)
How blows to the head cause numerous small swellings along the length of neuronal axons
Researchers from The Ohio State University have discovered how blows to the head cause numerous small swellings along the length of neuronal axons. (2017-06-12)
Study identifies an enzyme inhibitor to treat Gulf War illness symptoms
Scientists shed light on the neurological consequences of exposure to low-levels of nerve agents and suggest a drug that could treat some of the toxins' effects. (2017-06-06)
New mechanism behind Parkinson's disease revealed
OIST researchers have identified the precise toxic mechanism at work during an overabundance of the protein alpha-synuclein in neurons -- the protein is a key causative agent in the development of Parkinson's disease. (2017-06-02)
Excess transcription factor Heat Shock Factor 1 can delay embryonic neural migration
Transcription factor Heat Shock Factor 1, which the developing brain releases to shield the vital organ from the ravages of environmental stress, actually can contribute to impairing the embryonic brain when too much Hsf1 is produced, research led by Children's National Health System scientists indicates. (2017-05-02)
New insight into brain development disorder
Two years ago, the Zika virus drew attention to microcephaly, a developmental disorder in which the brain and skull display inhibited growth. (2017-04-24)
Natural experiment, dogged investigation, yield clue to devastating neurological disease
After a 29-year quest, Ian Duncan, a professor of veterinary medicine at the University of Wisconsin-Madison, has finally pinpointed the cause of a serious neurologic disease in a colony of rats. (2017-04-19)
Ladies, this is why fertility declines with age
Researchers at the University of Montreal Hospital Research Center (CRCHUM) have discovered a possible new explanation for female infertility. (2017-04-03)
Researchers identify protein essential for healthy gut cell development
Scientists have uncovered key processes in the healthy development of cells which line the human gut, furthering their understanding about the development of cancer. (2017-02-07)
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