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Current Mitochondria News and Events, Mitochondria News Articles.
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Discovery of proteins that regulate interorganelle communication
This groundbreaking discovery of the key factor in the formation of MAM is expected to contribute to research on Neurodegenerative Diseases. (2020-06-02)
Temple researchers track new path to therapeutic prevention of abdominal aortic aneurysm
New research by scientists at the Lewis Katz School of Medicine at Temple University suggests that abdominal aortic aneurysm (AAA) can be prevented therapeutically. (2020-05-28)
Subcellular chatter regulates longevity
As people get older, they often feel less energetic, mobile or active. (2020-05-19)
General descriptor sparks advancements in dye chemistry
SUTD collaborates with international researchers to move away from inefficient trial-and-error developments in dye chemistry and quantitatively design luminescent materials. (2020-05-14)
High calcium levels in mitochondria linked to neuronal death in Alzheimer's disease
For the first time, using a mouse model of Alzheimer's disease, scientists at Massachusetts General Hospital have documented a link between raised levels of calcium in mitochondria and neuronal death in the living brain. (2020-05-12)
Temple finds link between blood vessel inflammation, malfunctioning cellular powerhouses
In new research, scientists at the Lewis Katz School of Medicine at Temple University have uncovered a novel mechanism by which abnormalities in mitochondrial fission in endothelial cells contribute to inflammation and oxidative stress in the cardiovascular system. (2020-05-11)
First simulation of a full-sized mitochondrial membrane
Scientists from the University of Groningen have developed a method that combines different resolution levels in a computer simulation of biological membranes. (2020-05-08)
New molecular auto-control system to avoid an excessive brown adipose tissue activity
A scientific team found a new metabolism regulation system for the brown adipose tissue using the kallikrein-kinin hormonal system, so far related to the physiology of the renal and cardiovascular system and inflammation and pain processes. (2020-05-07)
For ME/CFS patients, viral immunities come at a devastating, lifelong cost
Researchers at UC San Diego School of Medicine and three German universities describe an underlying biological basis for myalgic encephalomyelitis/chronic fatigue syndrome, illustrating how efforts by the body to boost immune system protections can come at physiological cost elsewhere. (2020-04-27)
Study reveals importance of mitochondrial small proteins in energy production
A small mitochondrial protein is necessary for energy production and its malfunction could be behind a range of degenerative diseases, according to study by Duke-NUS Medical School and their collaborators. (2020-04-16)
Study finds evidence for existence of elusive 'metabolon'
For more than 40 years, scientists have hypothesized the existence of enzyme clusters, or 'metabolons,' in facilitating various processes within cells. (2020-04-16)
Crohn's disease: Preserving inflammation-free phases
Crohn's disease is a chronic inflammatory disorder of the intestine that, in most cases, relapses episodically. (2020-04-15)
New research insights into how a group of novel organelle-based disorders affects cells
A pioneering study has shed new light on how a group of novel organelle-based disorders affect cells. (2020-04-09)
Repair instead of renew: Damaged powerhouses of cells have their own 'workshop mode'
CECAD-researchers find a molecular repair pathway for cellular energy production, publication in 'Nature Communications' (2020-04-02)
Exeter researchers discover a novel chemistry to protect our crops from fungal disease
Exeter researchers have discovered a novel chemistry to protect our crops from fungal disease. (2020-03-30)
New mechanism underlying organelle communication revealed in brown fat cells
A new study reveals an underappreciated interplay between the endoplasmic reticulum and the mitochondria with implications for weight loss and disease. (2020-03-30)
How trans fats assist cell death
Tohoku University researchers in Japan have uncovered a molecular link between some trans fats and a variety of disorders, including cardiovascular and neurodegenerative diseases. (2020-03-25)
UCI team demonstrates ability to supercharge cells with mitochondrial transplantation
UCI researchers have shown that they can give cells a short-term boost of energy through mitochondrial transplantation. (2020-03-23)
New research may help older adults stay physically capable for longer
Drug therapies that help older adults maintain their skeletal muscle mass and physical function for longer could be a step closer after researchers at the University of Birmingham identify a key mechanism that drives the clearance of damaged mitochondria. (2020-03-22)
Antioxidant treatment in acute ischemic stroke may delay the onset of Alzheimer's dementia
There is a considerable overlap between vascular risk factors and risk factors of Alzheimer's disease (AD). (2020-03-17)
Cell biology -- maintaining mitochondrial resilience
Mitochondria cannot autonomously cope with stress and must instead call on the cell for help. (2020-03-09)
Yale researchers help restore hormonal balance disrupted in metabolic diseases
Many health problems in the developed world stem from the disruption of a delicate metabolic balance between glucose production and energy utilization in the liver. (2020-03-04)
Boosting energy levels within damaged nerves may help them heal
When the spinal cord is injured, the damaged nerve fibers -- called axons -- are normally incapable of regrowth, leading to permanent loss of function. (2020-03-03)
Blocking energy production in immune cells helps tumours escape treatment
A small molecule that inhibits energy production in immune T-cells allows some tumours to escape treatment with an immunotherapy called PD-1 blockade therapy, says a study in mice published today in eLife. (2020-03-03)
IU scientists study link between energy levels, spinal cord injury
A team of researchers from Indiana University School of Medicine, in collaboration with the National Institute of Neurological Disorders and Stroke, have investigated how boosting energy levels within damaged nerve fibers or axons may represent a novel therapeutic direction for axonal regeneration and functional recovery. (2020-03-03)
Mayo Clinic researchers clarify how cells defend themselves from viruses
A protein known to help cells defend against infection also regulates the form and function of mitochondria, according to a new paper in Nature Communications. (2020-03-03)
Oncotarget | SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism
Oncotarget Volume 11 Issue 8 reported that while it is known that cancer cells require one-carbon and FAD-dependent mitochondrial metabolism to sustain cell proliferation, the role of SLC25A32 in cancer cell growth remains unexplored. (2020-02-28)
Scientists find link between genes and ability to exercise
A team of researchers have discovered a genetic mutation that reduces a patient's ability to exercise efficiently. (2020-02-26)
Study detects abnormally low levels of a key protein in brains of young men with autism
Brains of young men with autism spectrum disorder (ASD) have low levels of a protein that appears to play a role in inflammation and metabolism. (2020-02-21)
Changing what heart cells eat could help them regenerate
Switching what the powerhouses of heart cells consume for energy could help the heart regenerate when cells die. (2020-02-21)
A deep dive into cellular aging
Scientists at Sanford Burnham Prebys and Harvard University have discovered that mitochondria trigger senescence, the sleep-like state of aged cells, through communication with the cell's nucleus--and identified an FDA-approved drug that helped suppress the damaging effects of the condition in cells and mice. (2020-02-20)
This study shows how a lack of oxygen during pregnancy can cause schizophrenia
Experiments with rats indicate that brain cells submitted to several forms of hypoxia underwent alterations to their energy production mechanism. (2020-02-20)
A new model of the worm C. elegans to progress in the study of a rare disease
he IDIBELL Neurometabolic Diseases group, with international collaboration, has identified a model of chromosome X-linked adrenoleukodystrophy (x-ALD) in the earthworm C. elegans, this is a rare disorder of the nervous system with no treatment available. (2020-02-19)
Unexpected insights into the dynamic structure of mitochondria
As power plants and energy stores, mitochondria are essential components of almost all cells in plants, fungi and animals. (2020-02-18)
Targeting turncoat immune cells to treat cancer
A Ludwig Cancer Research study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh microenvironment of the tumor. (2020-02-18)
SR-FACT microscopy reveals the landscape of the cellular organelle interactome
We developed super-resolution fluorescence-assisted diffraction computational tomography(SR-FACT), which combines three-dimensional optical diffraction tomography with two-dimensional fluorescence Hessian structured illumination microscopy. (2020-02-17)
X-ray microscopy at BESSY II: Nanoparticles can change cells
Nanoparticles easily enter into cells. New insights about how they are distributed and what they do there are shown for the first time by high-resolution 3D microscopy images from BESSY II. (2020-02-12)
Parkinson's and the immune system
Mutations in the Parkin gene are a common cause of hereditary forms of Parkinson's disease. (2020-02-05)
Study provides new understanding of mitochondria genome with potential for new avenues of treatment for multiple cancers
A study led by The University of Texas MD Anderson Cancer Center furthered understanding about mitochondria, the cell components known as the 'powerhouse of the cell.' Knowing more about the genome is crucial given that mitochondria play important roles in tumorigenesis. (2020-02-05)
Structural biology: Special delivery
Bulky globular proteins require specialized transport systems for insertion into membranes. (2020-02-03)
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