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Current Mitochondria News and Events, Mitochondria News Articles.
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Autophagy and mitochondria: Targets in neurodegenerative disorders
Cellular homeostasis depends on the timely clearance of damaged cellular organelles and proteins via pathways including autophagy. (2018-12-26)
Pitt-led research describes how neurons could disconnect from each other in Huntington's disease
Newly described mechanism called 'neuritosis' could play an important role in normal brain development, aging and neurodegenerative disease. (2018-12-24)
Parkinson's disease protein buys time for cell repair
Loss of the protein Parkin causes certain forms of Parkinson's disease, a neurodegenerative condition involving death of neurons. (2018-12-20)
Scientists uncover how protein clumps damage cells in Parkinson's
Research into the root cause of Parkinson's aims to advance work on a disease-modifying treatment. (2018-12-20)
Temple-led research team traces pathway to cardioprotection in post-ischemic heart failure
During an ischemic attack, the heart is temporarily robbed of its blood supply. (2018-12-11)
Elevated hormone flags liver problems in mice with methylmalonic acidemia
NHGRI researchers have discovered a hormone in a mouse study that can be used immediately to can help doctors predict how severely patients with the rare disease methylmalonic acidemia are affected and when to refer them for liver transplants. (2018-12-06)
Nanoscale tweezers can perform single-molecule 'biopsies' on individual cells
Using electrical impulses, the 'tweezers' can extract single DNA, proteins and organelles from living cells without destroying them. (2018-12-03)
Newfound mechanism may yield ways to counter mistaken immune attack on body
A newfound genetic regulatory mechanism may shape the immune system's ability to fight viral infections, and play a key role in autoimmune diseases. (2018-11-27)
Why small size matters: Tiny mitochondria stimulate brain cell connections
This research, published online today in Nature Communications, suggests that these unusually small, squat mitochondria help neurons grow and make proper connections in the developing brain. (2018-11-27)
Fine-tuning cell death: New component of death machinery revealed
An important component of the microscopic machinery that drives cell death has been identified by Australian scientists. (2018-11-26)
'Longevity Protein' rejuvenates muscle healing in old mice
A protein found in healing muscles of younger mice helps older animals bounce back from injury. (2018-11-21)
Helping to transport proteins inside the cell
Researchers from the University of Freiburg have discovered how proteins are transported to the cell's power stations. (2018-11-21)
Proteins cooperate to break up energy structures in oxygen starved heart cells
Researchers at the National Institute for Physiological Sciences found that the filamin A-Drp1 complex mediates mitochondrial fission in a mouse model of hypoxic heart cells. (2018-11-16)
Channels for the supply of energy
Freiburg scientists elucidate the mechanism for the transport of water-insoluble protein molecules in mitochondria (2018-11-16)
New way to look at cell membranes could change the way we study disease
Researchers have developed a new technique to analyse cell membrane proteins in situ which could revolutionise the way in which we study diseases, such as cancer, metabolic and heart diseases. (2018-11-16)
How mitochondria deploy a powerful punch against life-threatening bacteria
Researchers discover that mitochondria play an important role in supporting the immune system's response against MRSA infection. (2018-11-12)
Big change from small player -- Mitochondria alter body metabolism and gene expression
Mitochondria have their own DNA, but the 13 genes in human mitochondria -- along with DNA sequences for tRNAs, rRNAs and some small peptides -- are massively overshadowed by the 20,000 genes in the human nucleus. (2018-11-09)
RNA-protein network may explain why melanoma grows more
A collaboration led by scientists from KU Leuven, Belgium, with Tokyo University of Agriculture and Technology (TUAT), Japan, revealed a new way to fight melanoma. (2018-10-29)
Synthetic microorganisms allow scientists to study ancient evolutionary mysteries
Scientists at Scripps Research and their collaborators have created microorganisms that may recapitulate key features of organisms thought to have lived billions of years ago. (2018-10-29)
Tampering with cellular fats holds great promise
Researchers have found a way to engineer the lipid composition of cell membranes. (2018-10-26)
Study opens new therapeutic avenue for mitochondria malfunction
Jefferson scientists identify key interaction controlling calcium's access to the cell's powerhouse. (2018-10-25)
Advanced sequencing technology provides new insights into human mitochondrial diseases
Researchers have for the first time been able to investigate the abundance and methyl modifications of all mitochondrial tRNAs in patients suffering from one of the most common inherited mitochondrial tRNA mutations. (2018-10-18)
How a common drug causes liver failure
A study of liver cells exposed to the common painkiller acetaminophen found a novel mechanism for the drug's toxicity at high doses. (2018-10-11)
Cells in 'little brain' have distinctive metabolic needs
'Knocking out' an enzyme that regulates the flow of fuel into mitochondria specifically blocks the development of the mouse cerebellum more than the rest of the brain. (2018-10-10)
New discovery restores insulin cell function in type 2 diabetes
By blocking a protein, VDAC1, in the insulin-producing beta cells, it is possible to restore their normal function in case of type 2 diabetes. (2018-10-08)
Chemotherapy may lead to mitochondrial dysfunction in skeletal muscle
Chemotherapy drugs to treat breast cancer may promote muscle mitochondrial dysfunction, according to new research. (2018-10-04)
CU Anschutz scientists identify genetic causes of mitochondrial diseases
An international team of scientists led by researchers from the University of Colorado School of Medicine have identified previously unknown genetic causes of mitochondrial diseases. (2018-10-03)
Ciprofloxacin has dramatic effects on the mitochondrial genome
A study carried out at the University of Eastern Finland and published in Nucleic Acids Research investigated the effect of ciprofloxacin on mitochondria, the important cell organelles in our body that produce the energy for cellular function. (2018-10-01)
New insights into the structure of a killer protein
Researchers at Ruhr-Universität Bochum and the University of Tübingen have gained new insights into the structure of the killer protein Bax. (2018-09-28)
Mitochondrial diseases could be treated with gene therapy, study suggests
Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases: serious and often fatal conditions which affect 1 in 5,000 people. (2018-09-24)
New research reveals a mitochondrial gene that protects against Alzheimer's disease
New research from USC has uncovered a previously unknown genetic risk factor for Alzheimer's disease and related dementias. (2018-09-21)
Crunched for time? High-intensity exercise = same cell benefits in fewer minutes
A few minutes of high-intensity interval or sprinting exercise may be as effective as much longer exercise sessions in spurring beneficial improvements in mitochondrial function, according to new research. (2018-09-20)
Distance helps re-fuel the heart
Separated entry and exit doors for calcium keep energy production smooth in the powerhouses of heart cells. (2018-09-18)
Big data studies scrutinize links between fatty liver disease and how cells make energy
Three recent studies investigate changes in mitochondria, the cell's energy producers, as fatty liver disease (NAFLD) progresses to steatohepatosis (NASH). (2018-09-14)
A very special protein synthesis machinery
Sleeping sickness-causing parasites contain an unusual protein synthesis machinery. A team of researchers from ETH Zurich and the University of Berne resolved its very special structure for the first time. (2018-09-13)
Mitochondria come together to kill cancer cells
Uncovered details of a molecular pathway in cancer cells could lead to improved treatment. (2018-09-12)
Sarcolipin tricks muscle cells into using more energy, burning fat
Ever wonder why you burn fat and heat up when you exercise or shiver? (2018-09-11)
Changes in mitochondrial DNA control how nuclear DNA mutations are expressed in cardiomyopathy
Differences in the DNA within the mitochondria, the energy-producing structures within cells, can determine the severity and progression of heart disease caused by a nuclear DNA mutation. (2018-09-11)
New discovery on T cell behavior has major implications for cancer immunotherapy
Scientists at the University of Colorado Anschutz Medical Campus have discovered that disease-fighting T cells, elicited from vaccines, do not require glucose for their rapid reproduction, a finding with major implications for the development of immunotherapies for cancer patients. (2018-09-07)
Unearthing the secrets of cellular energy
In a new study published in PLOS Biology, a team of scientists at the Gladstone Institutes and UC San Francisco (UCSF) led by Ken Nakamura, MD, PhD, used innovative technologies to generate the first large-scale list of genes that control the production of cellular energy. (2018-08-27)
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