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Current Mitral Valve News and Events, Mitral Valve News Articles.
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Ten-year results display strong safety and efficacy profile for TPV device
Ten-year follow-up results of the US Investigational Device Exemption (IDE) Trial of the Melody transcatheter pulmonary valve (TPV) were presented today during the SCAI 2020 Scientific Sessions Virtual Conference. Findings showed favorable outcomes for long-term function, safety, and efficacy for congenital patients who underwent Melody valve implantation within an existing dysfunctional right ventricular outflow tract (RVOT) conduit or bioprosthetic pulmonary valve. (2020-05-15)

With a heavy heart: How men and women develop heart disease differently
A new study by researchers from McGill University has uncovered that minerals causing aortic heart valve blockage in men and women are different, a discovery that could change how heart disease is diagnosed and treated. (2020-04-24)

A new strategy to create 2D magnetic order
Scientists based in China discover the spin-valve magnetoresistance at the ferromagnetic SrRuO3 grain boundary owing to the nature of non-magnetic metallic grain boundary revealed by electron microscopy and first principles calculations, providing a new strategy to create the low-dimensional magnetic order via defect engineering. (2020-04-10)

Medicare changes may increase access to TAVR
The number of hospitals providing TAVR could double with changes to Medicare requirements. Researchers see reason for both excitement and concern. (2020-04-06)

Repair instead of renew: Damaged powerhouses of cells have their own 'workshop mode'
CECAD-researchers find a molecular repair pathway for cellular energy production, publication in 'Nature Communications' (2020-04-02)

TAVR found non-inferior to surgery in broad patient population
Patients who underwent transcatheter aortic valve replacement (TAVR) did not have a higher rate of death at one year compared with those who had their heart valve replaced via open-heart surgery, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)

Study finds room for improvement in TAVR outcomes across US
Thirty-four medical centers, representing 11% of facilities that perform transcatheter aortic valve replacement (TAVR) in the U.S., saw worse than expected outcomes in terms of survival and quality of life among patients undergoing the procedure in an analysis presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)

Antiplatelet drugs increase risk for TAVR patients with atrial fibrillation
Patients with atrial fibrillation who took oral anticoagulants alone after undergoing transcatheter aortic valve replacement (TAVR) had a lower rate of bleeding complications without an increased risk of clotting-related complications compared to patients who took antiplatelet medication in addition to oral anticoagulants, in a trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)

TAVR equivalent to surgery at 2 years among low-risk patients
Patients undergoing transcatheter aortic valve replacement (TAVR) fared equally well compared with those undergoing open heart valve replacement surgery in terms of the combined risk of death, stroke or rehospitalization at two years, the primary endpoint of the PARTNER 3 trial being presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)

Frailty may be highly predictive of complications, death in patients with mitral valve disease
Frailty measurements have become increasingly important in assessing surgical risk in patients with mitral valve disease, and research published online today in The Annals of Thoracic Surgery shows that frailty plays a significant role in outcomes following mitral valve procedures. (2020-03-19)

World's first minimally invasive tricuspid valve replacement performed in Toronto
The world's first minimally invasive tricuspid valve replacement was performed at St. Michael's Hospital of Unity Health Toronto by Drs. Neil Fam, Mark Peterson and Geraldine Ong. (2020-03-11)

New type of heart valve may be the only replacement a child needs
Current prosthetic heart valves for children with congenital heart disease are fixed in size, requiring repeated open-heart surgeries during childhood to replace the valve with a larger version. But a surprising new design created at Boston Children's Hospital could allow children to keep the same prosthetic valve until adulthood, and could also benefit adults with heart valve defects. The new device is described in Science Translational Medicine, published online Feb. 19. (2020-02-19)

Size-adjustable prosthetic heart valve accommodates heart growth in sheep
Taking a step towards a major goal in heart valve prosthetics, scientists have created an adaptable heart valve replacement that can be expanded over time as the heart grows. (2020-02-19)

Research reveals link between high cholesterol levels and risk of aortic valve disease
Researchers from The George Institute for Global Health at the University of Oxford have found that while having high cholesterol levels does not influence your risk of aortic or mitral valve regurgitation, it does increase your risk of developing another major heart valve disease -- aortic stenosis. (2020-02-19)

Self-learning heat­ing control system saves energy
Can buildings learn to save all by themselves? Empa researchers think so. In their experiments, they fed a new self-learning heat­ing control system with temperature data from the previous year and the current weather forecast. The 'smart' control system was then able to assess the building's behavior and act with good anticipation. The result: greater comfort, lower energy costs. (2020-01-30)

NEJM: transcatheter aortic valve replacement shows similar safety outcomes as open-heart surgery
A new study from the Smidt Heart Institute at Cedars-Sinai and other centers nationwide shows that patients who underwent a minimally invasive transcatheter aortic-valve replacement (TAVR), had similar key 5-year clinical outcomes of death and stroke as patients who had traditional open-heart surgery to replace the valve. (2020-01-29)

Young age does not equal low risk for patients needing aortic valve replacement
While transcatheter aortic valve replacement (TAVR) continues to expand its pool of eligible patients, open heart surgery -- resulting in excellent patient survival and fewer strokes when compared to TAVR--is the best option for young and middle-aged adults with aortic valve disease -- at least for now. (2020-01-27)

Reducing the risk of blood clots in artificial heart valves
People with mechanical heart valves need blood thinners on a daily basis, because they have a higher risk of blood clots and stroke. Researchers at the ARTORG Center of the University of Bern, Switzerland, now identified the root cause of blood turbulence leading to clotting. Design optimization could greatly reduce the risk of clotting and enable these patients to live without life-long medication. (2020-01-13)

High lipoprotein(a) levels in type 1 diabetes linked to cardiovascular disease
High blood levels of the lipid lipoprotein(a) in people with type 1 diabetes add to the already elevated risk of developing cardiovascular disease, researchers from Karolinska Institutet in Sweden report in a paper published in the prestigious journal Diabetes Care. Lipoprotein(a) levels should therefore be measured in patients with type 1 diabetes and form part of the total risk assessment, say the researchers. (2019-12-18)

The Lancet: Drug could help reduce frequency of seizures for children with Dravet Syndrome, a severe treatment-resistant epilepsy, compared with placebo
Children with Dravet Syndrome given fenfluramine experienced a greater reduction in convulsive seizures, compared to patients given a placebo for a 14-week treatment period, according to a randomised controlled trial published in The Lancet. (2019-12-17)

Old drug offers new hope for children with devastating disorder
A drug that once helped obese adults lose weight, withdrawn from the market due to heart risks, may be safe and effective for children with a seizure disorder called Dravet syndrome, say researchers from UCSF Benioff Children's treatment centers. The drug fenfluramine was developed for pediatric use and found to decrease the number of seizures by more than half for many Dravet syndrome patients. (2019-12-17)

Turning to genetics to treat little hearts
Researchers makes a breakthrough in understanding the mechanisms of a common congenital heart disease. (2019-12-16)

Toward more efficient computing, with magnetic waves
MIT researchers have devised a novel circuit design that enables precise control of computing with magnetic waves -- with no electricity needed. The advance takes a step toward practical magnetic-based devices, which have the potential to compute far more efficiently than electronics. (2019-11-28)

Women with preeclampsia may be at greater risk for cardiac conditions later in life
Women who have gestational hypertension or preeclampsia in at least one pregnancy will have higher cardiovascular risk than women without such a history, and that this elevated risk persists at least into their 60s. (2019-11-11)

Study identifies challenges to neonatal resuscitation outside of hospitals
With about 62,000 babies born outside of hospitals each year, and 1 in 10 newborns needing help to start breathing, emergency medical services (EMS) responders must be ready to give expert newborn resuscitation care. However, new research being presented at the American Academy of Pediatrics (AAP) 2019 National Conference & Exhibition found many responders lack recent training in resuscitation techniques for infants and experience in caring for newborns. (2019-10-25)

Public reporting on aortic valve surgeries has decreased access, study finds
Public reporting on aortic valve replacement outcomes has resulted in fewer valve surgeries for people with endocarditis, a new study has found. The researchers looked at national data from people with injection drug use and non-injection drug use-associated endocarditis and found that these patients were 30 percent less likely to receive valve surgery two years after outcomes data become public than before. (2019-10-11)

Risk of heart valve infections rising in hospitals
People with heart disease or defective or artificial heart valves are at increased risk of developing a potentially deadly valve infection. Rutgers researchers reported that new risk factors for this condition have emerged and that an increasing number of patients admitted to hospitals for other diseases are at risk of contracting this potentially lethal cardiac infection. (2019-09-29)

Antibody 'road block' enables fine-tuning for cardiac recovery
A new study published by Vanderbilt mechanobiology researchers details a possible solution for fine-tuning inflammation and cellular activity in cardiac recovery -- thanks to an antibody initially developed for rheumatoid arthritis.  (2019-09-19)

Defective cilia linked to heart valve birth defects
Bicuspid aortic valve (BAV), the most common heart valve birth defect, is associated with genetic variation in human primary cilia during heart valve development, report Medical University of South Carolina researchers in Circulation. Crucial to cilia development is the exocyst, which shuttles cilia cargo to the cell membrane. Disrupting the exocyst impaired ciliogenesis and caused a spectrum of cardiac defects in zebrafish and BAV in mice. The findings could inspire new therapeutic strategies. (2019-09-16)

Bioengineers explore cardiac tissue remodeling after aortic valve replacement procedures
Researchers have developed biomaterial-based 'mimics' of heart tissues to measure patients' responses to an aortic valve replacement procedure, offering new insight into the ways that cardiac tissue re-shapes itself post-surgery. (2019-09-11)

Commonly used antibiotics may lead to heart problems
Scientists have shown for the first time a link between two types of heart problems and one of the most commonly prescribed classes of antibiotics. (2019-09-10)

Study finds cellular processes controlling the formation of lymphatic valves
A mouse model study led by the University of South Florida Health (USF Health) Morsani College of Medicine has identified new cellular processes controlling development of the small valves inside lymphatic vessels, which prevent lymph fluid from flowing the wrong way back into tissues. The new findings suggest that targeting signaling pathways involved in creating and maintaining lymphatic valves may be a viable therapy for patients coping with lymphedema. (2019-08-27)

Bioprinting complex living tissue in just a few seconds
Researchers from EPFL and the University Medical Center Utrecht in the Netherlands have developed an extremely fast optical method for sculpting complex shapes in stem-cell-laden hydrogels and then vascularizing the resulting tissue. Their groundbreaking technique stands to change the field of tissue engineering. (2019-08-23)

Listening to the 'patient voice' can drive improvements in hospital care for patients undergoing heart surgery
Patient-reported experiences have potential for driving improvements in the quality of hospital care, according to a new study in the Canadian Journal of Cardiology, published by Elsevier. Investigators report on an analysis of the Canadian Patient Experience Survey responses obtained from cardiac patients in Alberta, which revealed areas that are highly rated by patients, but also reported findings around areas that could be the subject of future patient-centered quality improvements. (2019-08-22)

Innovative valve train saves 20% fuel
Empa has developed an innovative, electrohydraulically actuated valve train for internal combustion engines, that enables completely free adjustment of stroke and timing, while at the same time being robust and cost effective. This valve train was mounted on a serial production engine and has been running successfully for several months. The new technology saves up to 20% fuel. (2019-08-19)

Paper trail leads to heart valve discoveries
Rice University bioengineers are studying heart disease with paper-based structures that mimic the layered nature of aortic valves, the tough, flexible tissues that keep blood flowing in one direction only. The devices allow them to see in detail how calcifying diseases slow or stop hearts from functioning. (2019-08-05)

Study debunks 'July Effect' for heart surgery
The notion that more medical errors occur in July compared to other months due to an influx of new medical school graduates starting their in-hospital training does not apply to heart surgery, according to research in The Annals of Thoracic Surgery, published by Elsevier. (2019-07-31)

New insights into how the brain works
This study provides new insights into the functional relationships between inhibitory and excitatory neurons in the brain. (2019-07-29)

Cyborg-like microchip valve driven by earthworm muscle
Scientists at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan have developed the first microchip valve powered by living cells. Earthworm muscle tissue allowed for a high contractile force that could be sustained for minutes, and unlike electrically controlled valves, did not require any external power source such as batteries. (2019-07-09)

Scientists find potential way to defuse 'time bomb' of cardiology
In a new study published in EBioMedicine, researchers at Western University and Lawson Health Research Institute use principles from cancer biology to demonstrate what might be causing aortic aneurysms and potentially how to treat them. (2019-06-25)

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