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Current Molecular Imaging News and Events, Molecular Imaging News Articles.
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Computational method provides faster high-resolution mass spectrometry imaging
Researchers at the Beckman Institute have developed a computational strategy that enables faster chemical and spatial characterization of tissues. (2020-12-10)

Genetic differences important in Alzheimer's diagnosis
The two used methods for detecting amyloid pathology in Alzheimer's disease do not give unambiguous results, with the risk of incorrect or delayed care interventions. Now, researchers at Karolinska Institutet in Sweden have found genetic explanations for the differences. The study is published in Molecular Psychiatry and may be important for more individual diagnostics and the development of future drugs. (2020-12-10)

Filming roaming molecular fragments in real time
An international research team has captured roaming molecular fragments for the first time. (2020-12-09)

One for all
AI-based evaluation of medical imaging data usually requires a specially developed algorithm for each task. Scientists from the German Cancer Research Center (DKFZ) have now presented a new method for configuring self-learning algorithms for a large number of different imaging datasets - without the need for specialist knowledge or very significant computing power. (2020-12-07)

New method uses artificial intelligence to study live cells
A new study combines label-free imaging with artificial intelligence to study unlabeled live cells. This method has promising applications for samples that need to be observed over long periods without the use of labels. (2020-12-07)

Adaptive Image Receive (AIR) coil from GE shows promise for whole-brain imaging
According to an article in ARRS' American Journal of Roentgenology (AJR), a prototype 16-channel head Adaptive Image Receive (AIR) radiofrequency coil from GE Healthcare outperformed a conventional 8-channel head coil for in vivo whole-brain imaging, though it did not perform as well as a conventional 32-channel head coil. (2020-12-03)

Scientists invent a new type of microscope that can see through an intact skull
Researchers at IBS invented a new type of microscope called reflective matrix microscope, which uses adaptive optics techniques (2020-12-02)

Reconstruction of eye tissue gives new insight into outer retina
Researchers used a newly developed imaging technique called serial block face scanning electron microscopy, to produce a digital reconstruction of eye tissues from the outer retina, at very high resolution. This is the first time this technology has been used to fully reconstruct cells from the retina and could provide new insights into the causes of irreversible blinding diseases. (2020-12-02)

Post-COVID pain or weakness? Request an ultrasound or MRI
A new Northwestern Medicine study shows how advanced imaging technology can pinpoint what may have caused patients' nerve damage and help determine the best course of treatment. (2020-12-01)

Multi-center, multi-tracer PET studies harmonized to detect neuroinflammation in ALS
A novel ALS (amyotrophic lateral sclerosis) study has pooled data from multiple sites to effectively visualize neuroinflammation, which is key to developing drugs to treat the disease. Pooling data acquired from different scanners, different neuroinflammation positron emission tomography (PET) markers and different sites enhanced researchers' ability to detect neuroinflammation in ALS patients. This research was published in the November issue of The Journal of Nuclear Medicine. (2020-12-01)

Molecular 'barcode' helps decide which sperm will reach an egg
A protein called CatSper1 may act as a molecular 'barcode' that helps determine which sperm cells will make it to an egg and which are eliminated along the way. (2020-12-01)

How to spot winning sperm: examine their racing stripes
Millions of sperm enter the race to fertilize, but only one wins the sprint to the egg. Now Yale researchers have discovered that these winning sperm possess a few key molecular characteristics that differentiate them from those left behind, they report Dec. 1 in the journal eLife. (2020-12-01)

Holographic fluorescence imaging
A study in Science Advances by ICFO researchers, in collaboration with Massachusetts General Hospital, reports on a novel fluorescence holographic technique for the fast tracking of the 3D motion in cells. (2020-11-30)

Raman holography
Scientists from ICFO and University Rovira i Virgili report on a novel Raman holographic technique capable of tracking individual particles in 3D volumes from one single image. (2020-11-30)

Researchers develop low-cost, portable brain imaging scanner
Investigators have developed and tested a low-cost, compact, portable and low-power ''head only'' MRI scanner for brain tests. The scanner could allow for bedside brain imaging for patients or scanning in remote locations. (2020-11-24)

Team uses copper to image Alzheimer's aggregates in the brain
A proof-of-concept study conducted in a mouse model of Alzheimer's disease offers new evidence that copper isotopes can be used to detect the amyloid-beta protein deposits that form in the brains of people living with -- or at risk of developing -- Alzheimer's. (2020-11-24)

Replication cycle of SARS-CoV-2 in 3D
Researchers have studied SARS-CoV-2 replication in cells and obtained detailed insights into the alterations induced in infected cells. This information is essential to guide the development of urgently needed therapeutic strategies for suppressing viral replication and induced pathology. (2020-11-23)

Imaging method reveals a 'symphony of cellular activities'
MIT researchers have developed a way to simultaneously image up to five different molecules within a cell, by targeting glowing reporters to distinct locations inside the cell. This approach could allow scientists to learn much more about the complex signaling networks that control most cell functions. (2020-11-23)

Recording the symphony of cellular signals that drive biology
Like a computer, cells must process information from the outside world before they respond. Scientists have now developed a powerful new way to observe the internal discussions responsible for cellular decisions. (2020-11-23)

Food, housing insecurities may delay breast cancer diagnosis
Women who experience food or housing insecurity may be at risk for undiagnosed breast cancer due to lapses in follow-up appointments, according to research being presented at the annual meeting of the Radiological Society of North America (RSNA). (2020-11-19)

RIT students discover hidden 15th-century text on medieval manuscripts
Rochester Institute of Technology students discovered lost text on 15th-century manuscript leaves using an imaging system they developed as freshmen. By using ultraviolet-fluorescence imaging, the students revealed that a manuscript leaf held in RIT's Cary Graphic Arts Collection was actually a palimpsest, a manuscript on parchment with multiple layers of writing. (2020-11-19)

Mediastinal tuberculoma mimicking malignant cardiac tumor
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0587, Yiqian Ding, Wei Li, Yanqiu Liu, Min Ye, Liangping Cheng, Donghong Liu, Hong Lin and Fengjuan Yao from The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China consider mediastinal tuberculoma mimicking malignant cardiac tumors. (2020-11-19)

New technology allows more precise view of the smallest nanoparticles
Scientists have reported a new optical imaging technology, using a glass side covered with gold nanodiscs that allows them to monitor changes in the transmission of light and determine the characteristics of nanoparticles as small as 25 nanometers in diameter. (2020-11-16)

Are diagnostic imaging studies with positive conclusions or titles published faster?
According to the American Journal of Roentgenology, positive conclusions--but not titles--were associated with a shorter time from study completion to publication, which may contribute to an overrepresentation of positive results in the imaging diagnostic test accuracy (DTA) literature. Because an inflated perception of test performance could adversely influence clinical decision making and patient care, bias reduction strategies should undergo trials by both journal editors and researchers in the imaging DTA community. (2020-11-13)

Ultracompact metalens microscopy breaks FOV constraints
As reported in Advanced Photonics, their metalens-integrated imaging device (MIID) exhibits an ultracompact architecture with a working imaging distance in the hundreds of micrometers. Using a simple image-stitching process, they are able to obtain wide-field microscope imaging with large FOV and high resolution. (2020-11-13)

Illuminating tiny proteins in living cells using single-residue labeling tags
SciLifeLab Fellow Simon Elsässer laboratory at Karolinska Institutet reports a method, which allows fluorescent tagging of proteins with the small perturbation -- a single amino acid -- added genetically on either end of a (micro)protein of interest. The method is termed Single-residue Terminal Labeling, STELLA. (2020-11-12)

A survey on artificial intelligence in chest imaging of COVID-19
Announcing a new article publication for BIO Integration journal. In this review article the authors consider the application of artificial intelligence imaging analysis methods for COVID-19 clinical diagnosis. (2020-11-11)

Novel therapy approach for hyperinsulinemic hypoglycemia
A new method to treat hyperinsulinemic hypoglycemia has proven highly selective in targeting lesions and effective in slowing tumor growth, according to research published in the November issue of the Journal of Nuclear Medicine. (2020-11-08)

Review finds almost 20% of COVID-19 patients only show gastrointestinal symptoms
Almost one in five patients with COVID-19 may only show gastrointestinal symptoms, according to a review of academic studies published in the journal Abdominal Radiology. The findings of the review suggest abdominal radiologists need to remain vigilant during the pandemic while imaging patients. (2020-11-03)

Brain imaging of tau protein in patients with various forms of dementia
A new imaging-based method could enable the early detection and differentiation of neurodegenerative disorders characterized by the buildup of tau protein in the brain, suggests an October 29 in the journal Neuron. The researchers demonstrate that the method enables sensitive detection of tau deposits in mice and in patients with Alzheimer's disease and various frontotemporal lobar degeneration (FTLD) disorders. The authors say the approach could also be used to evaluate disease mechanisms or anti-tau therapies. (2020-10-29)

Smart fluorescent molecular switches based on boron-based compounds
Scientists have developed extremely stable molecular switches of high luminosity that self-assemble into 1D nanostructures and form gel-like materials. These molecular switches can be used in biomedicine as fluorescent probes for imaging or sensing, in fluorescent displays, or in memories and information processing devices. (2020-10-28)

New imaging technique doubles visibility of brain tumors in scans
A new three-dimensional imaging technique has been developed that greatly improves the visibility of brain tumors in magnetic resonance imaging scans. The technique will potentially enable earlier diagnosis of tumors when they are smaller and more treatable. (2020-10-28)

Adding advanced PET scans to radiation plans for prostate cancer increases FFS rates
Adding the advanced PET radiotracer fluciclovine to conventional imaging to help guide radiation treatments for recurrent prostate cancer can improve disease-free survival rates, a new study finds. Findings from the randomized phase II/III EMPIRE-1 trial (NCT01666808) will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-26)

ASTRO highlights Winship study showing increased failure-free survival in prostate cancer
The EMPIRE-1 trial is the first randomized trial of men with prostate cancer with recurring cancer to show that treatment based on advanced molecular imaging can improve disease-free survival rates. (2020-10-23)

Researchers solve 'protein paradox' and suggest way to exploit cancer weakness
Researchers from UCPH have discovered how thus far a mysterious function of the so-called MCM proteins protect the human cells against DNA instability, which can cause devastating diseases including cancer. In addition to their known role as molecular motors of genome duplication, MCM proteins control the speed of this process. How cells manage to constrain the speed of DNA replication has puzzled researchers for decades and has even been called a ''MCM paradox''. (2020-10-22)

Tracer molecule may improve imaging tests for brain injury
Researchers have validated a new radiolabeled molecule that can be used with imaging tests to accurately detect and characterize brain injury. (2020-10-22)

Spectral CT improves detection of early-stage coronavirus disease (COVID-19)
According to an open-access article in ARRS' American Journal of Roentgenology (AJR), the use of spectral CT with electron density imaging could improve the assessment of lung lesion extent in patients with early-stage coronavirus disease (COVID-19). (2020-10-21)

More research needed to determine safety of hip and knee steroid injections
Although frequently used to treat painful osteoarthritis of the hip and knee, intra-articular corticosteroid (IACS) injections remain controversial. Questions about whether damage to joints occurs as a result of these injections, which are performed thousands a time each day, persist. (2020-10-20)

An integrated approach to ultrasound imaging in medicine and biology
Announcing a new article publication for BIO Integration journal. In this editorial, Co-Editor-in-Chief, Pingtong Huang considers an integrated approach to ultrasound imaging in medicine and biology. (2020-10-19)

With deep learning algorithms, standard CT technology produces spectral images
In research published today in Patterns, a team of engineers from Rensselaer Polytechnic Institute demonstrate how a deep learning algorithm can be applied to a conventional computerized tomography (CT) scan in order to produce images that would typically require a higher level of imaging technology known as dual-energy CT. (2020-10-19)

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