Current Molecular News and Events

Current Molecular News and Events, Molecular News Articles.
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New microscopy analysis allows discovery of central adhesion complex
Researchers at University of Münster and the Max Planck Institute of Biochemistry have developed a method for determining the arrangement and density of individual proteins in cells. In this way, they were able to prove the existence of an adhesion complex consisting of three proteins. (2021-02-15)

New mechanism of force transduction in muscle cells discovered
Researchers at the University of Münster (Germany) have now discovered how the muscle-specific adhesion molecule metavinculin modulates mechanical force transduction on the molecular level. The research results have just been published in the journal Nature Communications. (2020-12-18)

NUS researchers solve decades-old problem of how to uniformly switch memristors
An international team, led by the scientists from the National University of Singapore, has developed a solution to uniformly switch memristors. This innovation addresses a long-standing problem in the field of organic and molecular electronics. (2020-09-29)

Organic chemistry -- a brilliant tool
An international team led by the chemist Heinz Langhals of LMU Munich succeeded in molecular deflection of light radiation by means of Diamantane. Novel applications such as efficient light collectors or broadband light absorbers are promising. (2020-08-14)

Synthetic drug ebselen could be repurposed to treat SARS-CoV-2 by targeting main protease at distant
The synthetic drug ebselen can bind to both the catalytic region and a previously unknown distant site on the SARS-CoV-2 virus' main protease, according to a molecular simulation analysis of the drug's interactions with this enzyme. (2020-08-14)

Recipe for success -- interaction proteomics become a household item
A research team from University of Helsinki introduces a new optimised and integrated interaction proteomics protocol that combines two state-of-the art methods to allow rapid identification of protein-protein interactions and more. (2020-08-11)

Researchers create a photographic film of a molecular switch
Molecular switches are the molecular counterparts of electrical switches and play an important role in many processes in nature. Nanotechnologist now produced a photographic film at the atomic level and thus tracked the motion of a molecular building block. The result was a light-controlled 'pedalo-type motion', going forward and backward. The study has been published in the ''The Journal of Physical Chemistry Letters''. (2020-06-18)

IASLC survey: Molecular testing rates in most countries less than 50 percent
Access to targeted therapies for lung cancer depends on accurate identification of patients' biomarkers through molecular testing, but survey results published today in the Journal of Thoracic Oncology suggest that many international clinicians are unaware of evidence-based guidelines that support the use of molecular testing. (2020-05-20)

Breakthrough in molecular machines
Molecular machines have the potential to revolutionize the future -- if we can find a way to control them. SDU researchers now report that they have found a way to control the small machines so that they move in a certain direction -- for example, into the bloodstream (2020-05-04)

Tiny, erratic protein motor movements revealed
The smallest proteins travel in our cells, completing deeply important tasks to keep our molecular mechanisms moving. They are responsible for transporting cargo, duplicating cells and more. Now, a research team based in Japan has uncovered more about how these proteins move. (2020-02-14)

Nanotechnology: Putting a nanomachine to work
A team of chemists at Ludwig-Maximilians-Universitaet (LMU) in Munich has successfully coupled the directed motion of a light-activated molecular motor to a different chemical unit -- thus taking an important step toward the realization of synthetic nanomachines. (2020-01-30)

Molecular factories: The combination between nature and chemistry is functional
Researchers at the University of Basel have succeeded in developing molecular factories that mimic nature. To achieve this they loaded artificial organelles inside micrometer-sized natural blisters (vesicles) produced by cells. These molecular factories remain intact even after injection into an animal model and demonstrate no toxicity, as the team report in the scientific journal Advanced Science. (2020-01-09)

New MPMI focus issue seeks to improve management of virus-induced disease in crops
The January focus issue of the Molecular Plant-Microbe Interactions journal includes four reviews and several research articles covering a variety of current topics examining the cell biology of virus-plant and virus-vector interactions, including cellular RNA hubs, plasmodesmal functioning, tripartite interactions, mechanisms of host defense suppression, and biotechnological approaches to induce host resistance. (2020-01-08)

Chitin-binding proteins override host plant's resistance to fungal infection
A recent Molecular Plant-Microbe Interactions article studies chitin-binding proteins from a soilborne fungus (Verticillium nonalfalfae) that causes vascular wilt in plants. This fungus binds a particular protein (VnaChtBP) to chitin in order to abolish the host plant's chitin-triggered burst of reactive oxygen species and shield the fungus from being digested by the plant. (2019-11-13)

Molecular motors -- Rotation on an eight-shaped path
Chemical engineers at Ludwig-Maximilians-Universitaet (LMU) in Munich, Germany, have developed the first molecular motor that enables an eight-shaped movement. (2019-10-01)

A dual imaging approach may improve diagnosis and monitoring of prostate cancer
A new platform that combines two established imaging methods can peer into both the structure and molecular makeup of the prostate in men with prostate cancer. (2019-08-28)

OHIO professor Hla develops robust molecular propeller for unidirectional rotations
A team of scientists from Ohio University, Argonne National Laboratory, Universitié de Toulouse in France and Nara Institute of Science and Technology in Japan led by OHIO Professor of Physics Saw-Wai Hla and Prof. Gwenael Rapenne from Toulouse developed a molecular propeller that enables unidirectional rotations on a material surface when energized. (2019-08-20)

Researchers first to map structure of protein aggregate that leads to Alzheimer's
A research team including faculty at Binghamton University and University of Colorado Denver are the first to map the molecular structure of an aggressive protein aggregate that causes acceleration of Alzheimer's disease. (2019-08-12)

Galaxies as 'cosmic cauldrons'
Star formation within interstellar clouds of gas and dust, so-called molecular clouds, proceeds very rapidly yet highly 'inefficiently'. Most of the gas is dispersed by stellar radiation, revealing galaxies to be highly dynamic systems, like 'cosmic cauldrons', consisting of components that constantly change their appearance. A team of scientists led by astrophysicist Dr. Diederik Kruijssen from Heidelberg University has reached these conclusions based on new observations of the NGC 300 spiral galaxy. (2019-05-22)

Searching for the surface of water through a single molecule
By observing the spectroscopic behavior of single water molecules embedded in a super-cold, cage-like molecular structure, researchers have revealed key features that underlie the diffuse vibrational spectra of hydrogen-oxygen bonds that make studying the two-dimensional surface structure of water a challenge. (2019-04-18)

Protocells use DNA logic to communicate and compute
Researchers at the University of Bristol, Eindhoven University of Technology and Microsoft Research have successfully assembled communities of artificial cells that can chemically communicate and perform molecular computations using entrapped DNA logic gates. (2019-03-04)

Hachimoji -- Expanding the genetic alphabet from four to eight
A new form of synthetic DNA expands the information density of the genetic code, that likely preserves its capability for supporting life, according to a new study. (2019-02-21)

Molecular machinery that makes potent antibiotic revealed after decades of research
Scientists at Rutgers and universities in Russia, Poland and England have solved a nearly 30-year mystery -- how the molecular machinery works in an enzyme that makes a potent antibiotic. The findings, which appear in the journal Molecular Cell, provide the tools to design new antibiotics, anticancer drugs and other therapeutics. (2019-01-17)

Prospect. & struct. insight, binding plant-deriv. molecule of leea indica; inhibitor bace-1
Unveiled the lupeol as a potent BACE1 inhibitor from a manually curated dataset of Leea indica molecules, which may provide a new dimension of designing novel BACE1 inhibitors for AD therapy. (2018-12-19)

The feature size and functional range of molecular electronic devices
The tunneling leakage is a major quantum obstacle which hinders further miniaturization of electronic devices. To explore the miniaturization limits of molecular electronics, the oligo(aryleneethynylene) (OAE) molecules were employed to investigate the transition between through-space tunneling and molecular tunneling. For the shortest OAE molecule, the intrinsic single-molecule charge transport can be outstripped from tunneling leakage at 0.66 nm, suggesting the potential to push the miniaturization limit of molecular electronic devices to the angstrom scale. (2018-12-14)

A mechanistic approach to neuroblastoma prognosis and risk
A new study reveals key molecular indicators that could help doctors select the best form of treatment for patients with neuroblastoma -- the most common type of cancer in infants. (2018-12-06)

All wired up: New molecular wires for single-molecule electronic devices
Scientists at Tokyo Tech designed a new type of molecular wire doped with organometallic ruthenium to achieve unprecedentedly higher conductance than earlier molecular wires. The origin of high conductance in these wires suggests a potential strategy for developing of novel molecular components, which could be the building blocks of future minuscule electronic devices. (2018-08-28)

Hybrid catalyst with high enantiomer selectivity
A group of Japanese researchers has developed a technology to create a hybrid catalyst from simple-structured, commercially available rhodium and organic catalysts, which reduces chemical waste and produces molecules with high selectivity of an enantiomer, a pair of molecular structures that are non-superimposable mirror images of each other. This technology is expected to assist in rapid and low-cost drug synthesis. (2018-08-09)

A periodic table of molecular knots
Using computational predictive models, the scientists identified a shortlist, a kind of 'periodic table', of the most designable knot types, i.e. those knots that could easily self-assemble under appropriate physical and chemical conditions. This study, and the increasingly predictive capability of molecular modelling techniques, can create novel possible perspectives for future advanced applications, like the construction of sophisticated molecular machines for loading and delivering a nanocargo. (2018-08-03)

Molecular oxygen in comet's atmosphere not created on its surface
Scientists have found that molecular oxygen around comet 67P is not produced on its surface, as some suggested, but may be from its body. (2018-07-03)

Towards personalised medicine: One type of data is not enough
To understand the biology of diseased organs researchers can use different types of molecular data. One of the biggest computational challenges at the moment is integrating these multiple data types. A new computational method jointly analyses different types of molecular data and disentangles the sources of disease variability to guide personalised treatment. (2018-06-20)

Molecular scaffolding aids construction at the nanoscale
Researchers at OIST have made a nanoscale construction kit comprised of molecular 'bricks' and 'scaffolding,' inspired by the way the extracellular matrix is built around living cells. (2018-04-18)

Understanding charge transfers in molecular electronics
An international research team, which includes University of Central Florida Professor Enrique del Barco and Christian A. Nijhuis of the National University of Singapore, has found a way to understand and manipulate the transition of charges in molecular junctions. (2018-03-26)

An integrated workflow for interaction proteomics -- as versatile as the Swiss Army Knife
Researchers of the University of Helsinki, Finland, developed an integrated workflow for interaction proteomics, which -- as they describe it -- proves almost as versatile as the Swiss Army Knife. (2018-03-22)

Building molecular wires, one atom at a time
Researchers at OIST have found a simple way to construct and deconstruct molecular metal chains, atom-by-atom. (2018-01-17)

Bright and stable: New acid-tolerant green fluorescent protein for bioimaging
Fluorescent proteins (FPs) are powerful tools for visualization of molecular and cellular processes; however, most FPs lose fluorescence at a pH lower than their neutral pKa (~6). A team of Osaka University researchers developed the acid-tolerant green FP -- termed Gamillus -- cloned from flower hat jellyfish. Gamillus exhibits excellent brightness, maturation speed, and photostablity, even in low pH environments, making it a feasible molecular tag for imaging in acidic organelles. (2018-01-04)

Researchers find mechanism involved in novel drug design with potential to treat tuberculosis
Portuguese researchers successfully used a pioneer method to chemically modify a protein's components with potential medical applications and an impact in the fight against tuberculosis. (2017-10-12)

Scientists create world's first 'molecular robot' capable of building molecules
Scientists at the University of Manchester have created the world's first 'molecular robot' that is capable of performing basic tasks including building other molecules. (2017-09-20)

Techniques used in forensic science help discover new molecular fossils
Researchers in Japan and China believe they have found new molecular fossils of archaea using a method of analysis commonly used in forensic science. (2017-08-30)

A uranium-based compound improves manufacturing of nitrogen products
EPFL scientists have developed a uranium-based complex that can allow nitrogen fixation reactions to take place in ambient conditions. The work overcomes one of the biggest difficulties to building more efficient industrial-scale nitrogen products like ammonia. (2017-07-19)

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