Current Muscle Tissue News and Events

Current Muscle Tissue News and Events, Muscle Tissue News Articles.
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High energy radiotherapy could 'paint' tumours to avoid harming healthy tissue
A radiotherapy technique which 'paints' tumours by targeting them precisely, and avoiding healthy tissue, has been devised in research led by the University of Strathclyde. (2021-02-23)

New drug molecules hold promise for treating fatal child disease
Scientists have identified a way to ''rescue'' muscle cells that have genetically mutated, paving the way to a possible new treatment for rare childhood illness such as Duchenne Muscular Dystrophy (DMD). (2021-02-22)

Hormone helps prevent muscle loss in mice on high fat diets, USC study finds
A new study suggests that a hormone known to prevent weight gain and normalize metabolism can also help maintain healthy muscles in mice. The findings present new possibilities for treating muscle-wasting conditions associated with age, obesity or cancer, according to scientists from the University of Southern California Leonard Davis School of Gerontology. (2021-02-22)

Bioengineered hybrid muscle fiber for regenerative medicine
Scientists regenerate damaged muscle tissue using cell reprogramming technology and natural-synthetic hybrid scaffold. (2021-02-21)

Study reveals a new potential mechanism underlying loss of muscle mass during menopause
A new study conducted in collaboration between the universities of Minnesota (USA) and Jyväskylä (Finland) reveals that estrogen deficiency alters the microRNA signalling in skeletal muscle, which may activate signalling cascades leading to loss of muscle mass. (2021-02-18)

Radiological images confirm 'COVID-19 can cause the body to attack itself'
Muscle soreness and achy joints are common symptoms among COVID-19 patients. But for some people, symptoms are more severe, long lasting and even bizarre, including rheumatoid arthritis flares, autoimmune myositis or 'COVID toes.' A new Northwestern Medicine study has, for the first time, confirmed and illustrated the causes of these symptoms through radiological imaging. (2021-02-17)

People with this muscle protein gene variant tolerate the cold better
A gene variant that affects muscle function may have protected humans against cold during migrations from Africa to Europe more than 50,000 years ago, suggests a study appearing February 17 in the American Journal of Human Genetics. Researchers show that deficiency of a protein called α-actinin-3 caused by a gene variant improves cold tolerance in humans by increasing muscle tone. (2021-02-17)

One in five has a mutation that provides superior resilience to cold
Almost one in five people lacks the protein α-actinin-3 in their muscle fibre. Researchers at Karolinska Institutet in Sweden now show that more of the skeletal muscle of these individuals comprises slow-twitch muscle fibres, which are more durable and energy-efficient and provide better tolerance to low temperatures than fast-twitch muscle fibres. The results are published in the scientific journal The American Journal of Human Genetics. (2021-02-17)

Advances in x-ray imaging can help patients with breast cancer
A new approach to X-ray imaging can help surgeons performing breast cancer tumour removal surgery, giving 2.5 times better detection of diseased tissue around the edge of the tumour than with standard imaging. (2021-02-17)

3D microscopy clarifies understanding of body's immune response to obesity
Researchers who focus on fat know that some adipose tissue is more prone to inflammation-related comorbidities than others, but the reasons why are not well understood. Thanks to a new analytical technique, scientists are getting a clearer view of the microenvironments found within adipose tissue associated with obesity. This advance may illuminate why some adipose tissues are more prone to inflammation - leading to diseases like type 2 diabetes, cancer and cardiovascular disorders - and help direct future drug therapies to treat obesity. (2021-02-17)

FSU College of Medicine researcher develops new possibilities to prevent sudden cardiac death
Stephen Chelko, an assistant professor of biomedical sciences at the Florida State University College of Medicine, has developed a better understanding of the pathological characteristics behind arrhythmogenic cardiomyopathy, as well as promising avenues for prevention. (2021-02-17)

FRESH 3D-printing platform paves way for tissues, organs
Research into 3D bioprinting has grown rapidly in recent years as scientists seek to re-create the structure and function of complex biological systems from human tissues to entire organs. In APL Bioengineering, researchers from Carnegie Mellon University provide perspective on the Freefrom Reversible Embedding of Suspended Hydrogels 3D bioprinting approach, which solves the issue of gravity and distortion by printing within a yield-stress support bath that holds the bioinks in place until they are cured. (2021-02-16)

Ultrabright dots see beyond skin deep
Tiny light-emitting probes give researchers a better option for noninvasive imaging of living tissue. (2021-02-16)

IU researchers find disease-related gene changes in kidney tissue
Researchers from Indiana University have identified key genetic changes in the interstitial kidney tissue of people with diabetes, a discovery that signifies the potential for a revolutionary new genetic approach to the treatment of kidney disease. They will contribute their findings to the Kidney Precision Medicine Project's (KPMP) ''cell atlas,'' a set of maps used to classify and locate different cell types and structures within the kidney. (2021-02-16)

New surgery may enable better control of prosthetic limbs
MIT researchers in collaboration with surgeons at Harvard Medical School have devised a new type of amputation surgery that can help amputees better control their residual muscles and receive sensory feedback. This restored sense of proprioception should translate to better control of prosthetic limbs, as well as reduction of limb pain, the researchers say. (2021-02-15)

Researchers identify muscle factor that controls fat metabolism
In a recent study, published in The Journal of Clinical Investigation, University Hospitals (UH) Cleveland Medical Center and Case Western Reserve University School of Medicine researchers have found that skeletal muscle significantly affects how the body stores and metabolizes fat. (2021-02-15)

Research highlights ways to protect astronaut cardiovascular health from space radiation
In the inky blackness of space an invisible threat is ever present - radiation. It can have a huge array of negative effects on astronaut health, including cardiovascular disease. However, if we are ever to journey to the red planet, we will need to understand and reduce this risk. A new review charts a course through what we know about the cardiovascular risks of space radiation, and the best ways to protect space travelers. (2021-02-12)

Lifestyle changes in pregnant women affected babies' genes
A study led by researchers at Lund University in Sweden showed a connection between lifestyle intervention in pregnant women with obesity and epigenetic alterations in the baby. The study is published in the journal Diabetes. (2021-02-11)

New research identifies biological causes of muscle weakness in later life
A new largescale genetic analysis has found biological mechanisms that contribute to making people more susceptible to muscle weakness in later life, finding that diseases such as osteoarthritis and diabetes may play a large role in susceptibility. (2021-02-11)

How research on chronic illnesses will improve COVID-19 treatment
A new paper in Oxford Open Immunology, published by Oxford University Press, examines prior findings in the field of neuroimmunology that suggest potential treatment strategies for patients suffering long-term symptoms from COVID-19. (2021-02-10)

Novel protein could reverse severe muscle wasting in disease, aging and trauma
Muscle stem cells drive the tissue's growth and repair after such injuries. But growing these cells in the lab and using them to therapeutically replace damaged muscle has been frustratingly difficult. Australian researchers have discovered a factor that triggers these muscle stem cells to proliferate and heal. In a mouse model of severe muscle damage, injections of this naturally occurring protein led to the complete regeneration of muscle and the return of normal movement after severe muscle trauma. (2021-02-10)

Scientists switch on tissue repair in inflammatory bowel disease
Researchers have developed a method that instructs immune system cells to help repair damaged tissue in the intestine. The finding opens the way for more effective treatment of inflammatory bowel disease. (2021-02-08)

Higher blood pressure over life span increases congestive heart failure risk in Black people
Starting with early childhood, otherwise healthy Black people show signs of slightly diminished heart muscle strength and a slightly higher blood pressure than their white counterparts, factors which may put them on a course for early development of congestive heart failure, Medical College of Georgia researchers report. (2021-02-08)

Identification of three genes that determine the stemness of gastric tissue stem cells
Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages. However, detailed analysis in vivo is difficult, so the molecular mechanisms underlying the stemness of gastric tissue stem cells have remained a mystery. Here, by using organoids that mimic tissue structure and function in vivo and GeCKO screening to inactivate arbitrary genes, Alk, Bclaf3 and Prkra have been identified as genes regulating stemness. (2021-02-08)

Tiny sensor technique reveals cellular forces involved in tissue generation
A team of Brown University researchers developed a technique that uses tiny polymer spheres to sense the forces at play as body tissue forms and grows. (2021-02-05)

Uncovering a link between inflammation and heart disease
Patients with cardiac disease often have chronic inflammation that damages their hearts, even with no infection present. A new study published in Circulation reveals a mechanism that is activating T cells, a type of immune cell, and causing inflammation in the heart. (2021-02-04)

New clues to how muscle wasting occurs in people with cancer
Muscle wasting, or the loss of muscle tissue, is a common problem for people with cancer, but the precise mechanisms have long eluded doctors and scientists. Now, a new study led by Penn State researchers gives new clues to how muscle wasting happens on a cellular level. (2021-02-03)

Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders
A collaborative research group led by Professor Makoto Nakanishi of the Institute of Medical Science, The University of Tokyo (IMSUT) has identified an inhibitor of the glutamate metabolic enzyme GLS1 so that its administration selectively eliminates senescent cells in vivo. They confirmed that the GLS1 inhibitor eliminated senescent cells from various organs and tissues in aged mice, ameliorating age-associated tissue dysfunction and the symptoms of obese diabetes, arteriosclerosis, and NASH. The results of this research were published in 'Science' on January 15, 2021. (2021-02-03)

Generation of conjunctivae in a dish
Researchers from Osaka University generated functional conjunctival tissue in a dish. By identifying the protein epidermal growth factor and keratinocyte growth factor for the development and maturation of conjunctival cells, respectively, they showed functional, mucin-producing conjunctival tissues can be formed from human induced pluripotent stem cells. This study could help with identifying novel drugs for dry eye syndrome and could further open new avenues for regenerative therapies. (2021-02-02)

Toward safer steroids: Scientists devise method for improving safety of drug used to treat COVID-19, autoimmune disorders and more
Scripps Research scientists bring together multiple technologies to engineer potentially safer glucocorticoids, drugs used to treat COVID-19 and other conditions. (2021-02-02)

Stem cell study illuminates the cause of a devastating inherited heart disorder
Penn Medicine scientists have uncovered the molecular causes of a congenital form of dilated cardiomyopathy (DCM)-- one of multiple congenital disorders caused by inherited mutations in a gene called LMNA. The scientists used stem cell techniques to grow human heart muscle cells containing DCM-causing mutations in LMNA. They found that these mutations severely disrupt the structural organization of DNA in the nucleus of heart muscle cells. (2021-02-01)

Researchers map heart recovery after heart attack with great detail
Researchers from the Hubrecht Institute mapped the recovery of the heart after a heart attack with great detail. They found that cardiomyocytes play an important role in the intracellular communication after a heart attack. The researchers documented their findings in a database that is accessible for scientists around the world. This brings the research field a step closer to the development of therapies for improved recovery after heart injury. (2021-01-29)

Scientists use a novel ink to 3D print 'bone' with living cells
3D printers may one day become a permanent fixture of the operating theatre after UNSW scientists showed they could print bone-like structures containing living cells. (2021-01-25)

Identification of Oligo-DNA that promotes skeletal muscle differentiation
Skeletal muscle is the largest tissue in the human body and is responsible not only for locomotion but for energy metabolism and heat production. Myoblasts play an important role in maintaining muscle homeostasis, but it has been reported that the differentiation ability of myoblasts decreases with age and disease and this will be one of the causes of muscle atrophy. To prevent muscle atrophy, researchers of Shinshu University studied molecules that promote myoblast differentiation. (2021-01-25)

New variety of paintbrush lily developed by a novel plant tissue culture technique
Scientists at Hokkaido University and Chiba University have developed simultaneous triploid and hexaploid varieties of Haemanthus albiflos by the application of endosperm culture, thus extending the use of this technique. (2021-01-22)

Exercising muscle combats chronic inflammation on its own
Biomedical engineers at Duke University have demonstrated that human muscle has an innate ability to ward off damaging effects of chronic inflammation when exercised. The discovery was made possible through the use of lab-grown, engineered human muscle, demonstrating the potential power of the first-of-its-kind platform in such research endeavors. (2021-01-22)

Mechanism that produces rapid acceleration in clicking beetles identified
Snap-through unbending movement of the body is the main reason for the clicking beetle's fast acceleration. (2021-01-21)

New insights into wound healing process
Biomedical engineers developed a technique to observe wound healing in real time, discovering a central role for cells known as fibroblasts. The work, reported in APL Bioengineering, is the first demonstration of a wound closure model within human vascularized tissue in a petri dish. (2021-01-19)

NAD+ can restore age-related muscle deterioration
Scientists at EPFL have discovered that Alzheimer's-like protein aggregates underly the muscle deterioration seen in aging. But the aggregates can be reversed by boosting the levels of nicotinamide adenine dinucleotide (NAD+), which turns on the defense systems of mitochondria in cells and restores muscle function. (2021-01-19)

Canadian researchers create new form of cultivated meat
Researchers at Canada's McMaster University have developed a new form of cultivated meat using a method that promises more natural flavour and texture than other alternatives to traditional meat from animals. (2021-01-19)

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