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Current Nerve Cells News and Events, Nerve Cells News Articles.
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3-D imaging of fat reveals potential targets for new obesity treatments
With new imaging methods, scientists hope to make significant progress in the fight against obesity. A new report reveals striking images of neural projections within fat tissue, and clues for the development of new drugs. (2018-01-09)

In scientific first, IU researchers grow hairy skin in a dish
Researchers at Indiana University School of Medicine have successfully developed a method to grow hairy skin from mouse pluripotent stem cells -- a discovery that could lead to new approaches to model disease and new therapies for the treatment of skin disorders and cancers. (2018-01-05)

New brainstem changes identified in Parkinson's disease
A pioneering study has found that patients with Parkinson's disease have more errors in the mitochondrial DNA within the brainstem, leading to increased cell death in that area. (2018-01-04)

Gene therapy restores normal blood glucose levels in mice with type 1 diabetes
A study in Cell Stem Cell demonstrates that a gene therapy approach can lead to the long-term survival of functional beta cells as well as normal blood glucose levels for an extended period of time in mice with type 1 diabetes. The researchers used an adeno-associated viral (AAV) vector to deliver to the mouse pancreas two proteins, Pdx1 and MafA, which reprogrammed plentiful alpha cells into functional, insulin-producing beta cells. (2018-01-04)

How cholesterol contributes to age-related neuron impairment
A new study in mice sheds light on why neurons of older individuals are less able to repair their fatty, protective sheaths; excess cholesterol may be overburdening certain immune cells, resulting in lingering inflammation that interferes with the natural repair process. (2018-01-04)

Multiple sclerosis: Cholesterol crystals prevent regeneration in central nervous system
Multiple Sclerosis is a chronic inflammatory disease of the central nervous system, in which the immune cells attack myelin sheaths. Regeneration of myelin sheaths is necessary for patients to recover from MS relapses. Nevertheless, the ability to regenerate decreases with age. A team from Technical University Munich has published an explanation in (2018-01-04)

Advances in brain imaging settle debate over spread of key protein in Alzheimer's
Recent advances in brain imaging have enabled scientists to show for the first time that a key protein which causes nerve cell death spreads throughout the brain in Alzheimer's disease -- and hence that blocking its spread may prevent the disease from taking hold. (2018-01-04)

Diabetes drug 'significantly reverses memory loss' in mice with Alzheimer's
A drug developed for diabetes could be used to treat Alzheimer's after scientists found it 'significantly reversed memory loss' in mice through a triple method of action. This is the first time that a triple receptor drug has been used which acts in multiple ways to protect the brain from degeneration. It combines three growth factors. Problems with growth factor signalling have been shown to be impaired in the brains of Alzheimer's patients. (2017-12-31)

UCLA researchers report novel complementary effects of estrogen treatment in MS
A study reveals the cellular basis for how the hormone protects against damage to the central nervous system. (2017-12-28)

Researchers find potential path to repair MS-damaged nerves
Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases. For multiple sclerosis, specifically, increasing cholesterol synthesis gene expression in astrocytes of the spinal cord can be a pathway to repair nerves that affect walking. (2017-12-25)

Antidepressant may help combat the course of multiple sclerosis
The antidepressant clomipramine may also alleviate symptoms of multiple sclerosis, specifically in its progressive form, i.e. when it occurs without relapses or remissions. As yet, drugs for this type of MS have been virtually non-existent. Researchers screened 1,040 generic therapeutics and, based on preclinical studies, identified one that is suitable for the treatment of multiple sclerosis. They published their results in the journal Nature Communications from Dec. 19, 2017. (2017-12-20)

CRISPR treatment prevents hearing loss in mice
A single treatment of a genome editing agent partially preserved hearing in mice with genetic deafness. The work could one day help scientists treat certain forms of genetic hearing loss in humans. (2017-12-20)

'Simple, but powerful' model reveals mechanisms behind neuron development
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have now uncovered new insights into the regulatory network behind neuron growth. (2017-12-18)

Cellular self-digestion process triggers autoimmune disease
Autophagy allows cells to degrade and recycle their cellular components. Researchers at UZH have now demonstrated that the autophagy machinery in certain immune cells leads to the immune system attacking the central nervous system. The researchers are using these findings as a basis to look into new approaches to treating autoimmune diseases such as multiple sclerosis. (2017-12-13)

Researchers discover mechanism that allows rapid signal transmission between nerve cells
Researchers at Charité's NeuroCure Cluster of Excellence have successfully identified the mechanism behind rapid signal transmission. Their work, which has been published in the current issue of Nature Neuroscience*, shows that bridging by a specific protein is responsible for this high speed of transmission. (2017-12-13)

Structure of channelrhodopsin determined
Researchers discover structure and mechanism of action of molecular light switch, paving the way for new applications. (2017-12-13)

Spinal cord injury affects the heart
Spinal cord injury affects the heart, that's what research published in Experimental Physiology and carried out by researchers from University of British Columbia, Canada has found. (2017-12-12)

The direct route from A to C
We use specialized nerve cells for spatial orientation. The place cells fire whenever we stay in a particular place. The grid cells, on the other hand, measure distances and play a crucial role in path integration. So much for the theory. Scientists from the German Cancer Research Center (DKFZ) and the University Hospital Heidelberg have now, for the first time, provided experimental proof of this. (2017-12-11)

Scientists discover new way to help nerve regeneration in spinal cord injury
A new way of triggering nerve regeneration to help repair spinal cord injury and in the longer-term potentially paralysis has successfully been demonstrated by University of Bristol scientists. The work is published in PLOS ONE today. (2017-12-11)

Taurine lends hand to repair cells damaged in multiple sclerosis
New research suggests that administering taurine, a molecule naturally produced by human cells, could boost the effectiveness of current multiple sclerosis (MS) therapies. (2017-12-08)

How the cat parasite exploits immune cells to reach the brain
Scientists have previously shown that a parasite from cats can infect people's brain and affect our behaviour. Now, researchers at Stockholm University have discovered how the parasite takes control of our cells. (2017-12-07)

Experimental drug blocks toxic ion flow linked to Alzheimer's disease
A new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease. The molecule, called anle138b, works by stopping toxic ion flow in the brain that is known to trigger nerve cell death. Scientists envision that this drug could be used to treat Alzheimer's and other neurodegenerative diseases such as Parkinson's and ALS. (2017-12-05)

Restless sleep may be an early sign of Parkinson's disease
Researchers from Aarhus University have discovered that patients with the RBD sleep behavior disorder lack dopamine and have a form of inflammation of the brain. This means that they are at risk of developing Parkinson's disease or dementia when they grow older. (2017-12-05)

Lobachevsky University scientists create a neurochip for replacing damaged areas of the brain
Lobachevsky University researchers are working to create a neurochip capable of transmitting a signal to healthy brain cells. The neurochip can be used in devices intended to replace damaged parts of the brain. First experiments have been conducted to transmit signals from an artificial neuron to living cells of the brain slice, demonstrating the possibility of interfacing between them. (2017-12-05)

Visible signals from brain and heart
Key processes in the body are controlled by the concentration of calcium in and around cells. A team from the Technical University of Munich (TUM) and the Helmholtz Zentrum München have developed the first sensor molecule that is able to visualize calcium in living animals with the help of a radiation-free imaging technique known as optoacoustics. The method does not require the cells to be genetically modified and involves no radiation exposure. (2017-11-30)

Nerve cell findings may aid understanding of movement disorders
Fresh insights into the links between nerve and muscle cells could transform our understanding of the human nervous system and conditions relating to impaired movement. (2017-11-29)

Simple blood test may predict MRI disease activity in MS
A blood test to monitor a nerve protein in the blood of people with multiple sclerosis (MS) may help predict whether disease activity is flaring up, according to a study published in the Nov. 29, 2017, online issue of Neurology® Neuroimmunology and Neuroinflammation, an official journal of the American Academy of Neurology. (2017-11-29)

Quest for new medicines could be helped by cell discovery
Scientists at the University of Edinburgh have made a key discovery that could speed up the production of cells in the lab for studying diseases such as multiple sclerosis and Parkinson's disease. (2017-11-27)

New pain treatment tested in humans
Nerve growth factor signals through receptors of the tropomyosin-related kinase (Trk) family, and research in animals has shown that inhibitors of Trks A, B, and C can reduce pain. (2017-11-27)

Structure of primary optogenetic tool revealed
Attempts to solve the structure of ChR2 go right back to the time of its discovery in 2003. But despite the efforts of numerous research groups from across the world, the structure of the protein in its natural state has remained unknown. Now that researchers have the structure, meaningful mutations can be introduced into the protein to adjust its properties to the requirements of a specific experiment. (2017-11-27)

The piezoelectric effect of lysozyme was experimentally proved
A group of researchers from the University of Limerick and Ural Federal University received direct evidence of the piezoelectric effect of lysozyme in monoclinic and tetragonal aggregate films of lysozyme. The sufficiently high piezoelectric coefficient is several times higher than that of the classical quartz piezoelectricity, which makes it possible to use this material for various biomedical purposes, for example, to generate electric charges in cells. (2017-11-23)

Neurobiology: The chemistry of memory
Learning requires the chemical adaptation of individual synapses. Researchers have now revealed the impact of an RNA-binding protein that is intimately involved in this process on learning and memory formation and learning processes. (2017-11-23)

Study reveals new mechanisms of cell death in neurodegenerative disorders
Researchers at King's College London have discovered new mechanisms of cell death, which may be involved in debilitating neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. (2017-11-22)

Good cells gone bad
A new study from The Scripps Research Institute (TSRI) is the first to show precisely how a process in nerve cells, called the S-nitrosylation (SNO) reaction, may contribute to Parkinson's disease. (2017-11-21)

Controlling diabetes with your phone might be possible someday
Nerve-stimulating procedures from ancient traditional acupuncture and the more modern electroacupuncture and neuromodulation relieves chronic pain, pelvic disorders and Parkinson's disease, and can be advantageous for treating inflammatory disorders like arthritis and deadly infections like sepsis. (2017-11-21)

How rogue immune cells cross the blood-brain barrier to cause multiple sclerosis
Drug designers working on therapeutics against multiple sclerosis should focus on blocking two distinct ways rogue immune cells attack healthy neurons, according to a new study in the journal Cell Reports. (2017-11-21)

Zika-related nerve damage caused by immune response to the virus
The immune system's response to the Zika virus, rather than the virus itself, may be responsible for nerve-related complications of infection, according to a Yale study. This insight could lead to new ways of treating patients with Zika-related complications, such as Guillain-Barré syndrome, the researchers said. (2017-11-20)

Researchers describe new biology of Alzheimer's disease
In a new study, researchers from Boston University School of Medicine (BUSM) describe a unique model for the biology of Alzheimer's disease (AD) which may lead to an entirely novel approach for treating the disease. The findings appear in the journal Nature Neuroscience. (2017-11-20)

Research reveals biological mechanism of a leading cause of childhood blindness
Scientists at the Virginia Tech Carilion Research Institute (VTCRI) have revealed the pathology of cells and structures stricken by optic nerve hypoplasia, a leading cause of childhood blindness in developed nations. (2017-11-16)

How to control traffic on cellular highways
Inside cells, protein 'motors' act like trucks on tiny cellular highways to deliver life-sustaining cargoes. Now a team led by Rutgers University-New Brunswick researchers has discovered how cells deploy enzymes to place traffic control and 'roadway under construction' signs along cellular highways. (2017-11-09)

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