Current Nerve Damage News and Events

Current Nerve Damage News and Events, Nerve Damage News Articles.
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BU researchers identify biochemical process responsible for producing toxic tau
Tau is a protein that helps stabilize the internal skeleton of nerve cells (neurons) in the brain. Groups of toxic tau protein, termed tau oligomers, drive disease progression and memory loss in Alzheimer's disease (AD). A new study from Boston University School of Medicine (BUSM) shows how these tau oligomers form, and, correspondingly, how they can be prevented. (2021-02-22)

Three longtime antibiotics could offer alternative to addictive opioid pain relievers
Three decades-old antibiotics administered together can block a type of pain triggered by nerve damage in an animal model, UT Southwestern researchers report. The finding, published online today in PNAS, could offer an alternative to opioid-based painkillers, addictive prescription medications that are responsible for an epidemic of abuse in the US. (2021-02-22)

Regular caffeine consumption affects brain structure
Coffee, cola or an energy drink: caffeine is the world's most widely consumed psychoactive substance. Researchers from the University of Basel have now shown in a study that regular caffeine intake can change the gray matter of the brain. However, the effect appears to be temporary. (2021-02-15)

Implant improves balance, movement and quality of life for people with inner ear disorder
Johns Hopkins Medicine researchers have shown that they can facilitate walking, relieve dizziness and improve quality of life in patients with BVH by surgically implanting a stimulator that electrically bypasses malfunctioning areas of the inner ear and partially restores the sensation of balance. (2021-02-11)

Function identified of 'mystery protein' that kills brain cells of people with Parkinson's
Scientists have made a 'vital step' towards understanding the origins of Parkinson's Disease - the fastest growing neurological condition in the world. A study published in Nature Communications today (Wednesday 10 February) presents a compelling new evidence about what a key protein called alpha-synuclein actually does in neurons in the brain. (2021-02-10)

Long-term environmental damage from transportation projects in Kenya, scientists warn
The construction of a major railway through Kenya will have long-term environmental impacts on the area, suggesting more work needs to be done to limit the damage on future infrastructure projects, a major study reveals. (2021-02-09)

Battling bugs help solve mysteries of weapon evolution
Scientists at the University of Arizona outfitted bugs with body armor and pitted them against each other in staged wrestling matches, all in the name of science. The findings shed light on how evolution has shaped the arsenal of weapons in the animal kingdom. (2021-02-04)

Zinc may help with fertility during COVID-19 pandemic, researchers report
Wayne State University School of Medicine researchers have reported that zinc supplements for men and women attempting to conceive either naturally or through assisted reproduction during the COVID-19 pandemic may prevent mitochondrial damage in young egg and sperm cells. (2021-02-04)

Remyelinating drug could improve vision in patients with multiple sclerosis
A team led by a biomedical scientist at the University of California, Riverside, reports a drug -- an estrogen receptor ligand called indazole chloride (IndCl) -- has the potential to improve vision in patients with multiple sclerosis, or MS. The study, performed on mice induced with a model of MS and the first to investigate IndCl's effect on the pathology and function of the complete afferent visual pathway, is published in Brain Pathology. (2021-02-02)

Neurons: 'String of lights' indicates excitation propagation
A type of novel molecular voltage sensor makes it possible to watch nerve cells at work. The principle of the method has been known for some time. However, researchers at the University of Bonn and the University of California in Los Angeles have now succeeded in significantly improving it. It allows the propagation of electrical signals in living nerve cells to be observed with high temporal and spatial resolution. (2021-02-02)

Controls needed to stop zebra mussels invading Great Britain
Research team call for more controls and monitoring around boat ramps to reduce the damage caused by zebra mussels. (2021-02-01)

Accurate drug dosages with proton traps
Researchers at Linköping University, Sweden, have developed a proton trap that makes organic electronic ion pumps more precise when delivering drugs. The new technique may reduce drug side effects, and in the long term, ion pumps may help patients with symptoms of neurological diseases for which effective treatments are not available. The results have been published in Science Advances. (2021-01-29)

Multiple sclerosis: Immune cells silence neurons by removing synapses
Damage to the brain gray matter plays an important role in the progression of multiple sclerosis. This study now shows that such damage can be caused by inflammatory reactions that lead to loss of synapses, which impairs neural activity. (2021-01-26)

Mouse study: gabapentin prevents harmful structural changes in spinal cord
Research led by The Ohio State University Wexner Medical Center and College of Medicine found that the widely prescribed pain-relief drug gabapentin can prevent harmful structural changes in the injured spinal cords of mice, and also block cardiovascular changes and immune suppression caused by spinal cord injury. (2021-01-26)

Epilepsy research focused on astrocytes
A significant number of epilepsy patients does not respond to currently available drugs. A collaboration between researchers in Japan and at the Heinrich Heine University Düsseldorf (HHU) now addressed a cell type in the brain that has so far not received much attention in epilepsy therapy. In the current edition of the Journal of Neuroscience, they describe that astrocytes might be a potential new target to better treat this disease. (2021-01-25)

Size of connections between nerve cells determines their signaling strength
Nerve cells communicate with one another via synapses. Neuroscientists at the University of Zurich and ETH Zurich have now found that these connections seem to be much more powerful than previously thought. The larger the synapse, the stronger the signal it transmits. These findings will enable a better understanding of how the brain functions and how neurological disorders arise. (2021-01-21)

Hair aging differs by race, ethnicity
While aging is an unavoidable biological process with many influencing factors that results in visible changes to the hair, there is limited literature examining the characteristics of hair aging across the races. Now a new study describes the unique characteristics of hair aging among different ethnicities that the authors hope will aid in a culturally sensitive approach when making recommendations to prevent hair damage during one's life-time. (2021-01-21)

Balancing brain cell activity
Electrical trigger sites in neurons surprisingly change with experience; they are either becoming smaller with increasing number of experiences and, vice versa, they grow larger when less input arrives in the brain. (2021-01-20)

Different types of neurons interact to make reaching-and-grasping tasks possible
Picking up that cup of coffee? New research from the Okinawa Institute of Science and Technology Graduate University finds that one type of neuron is necessary for the early part of the movement, another for aiming for the cup. (2021-01-19)

Parkinson's: Initial steps to show nerves their growth direction magnetically
One reason why nerve damage in the brain cannot regenerate easily is that the neurites do not know in which direction they should grow. A team of researchers from Ruhr-Universität Bochum (RUB), Sorbonne University Paris, and the Technische Universität Braunschweig is now working on showing them the direction using magnetic nanoparticles. (2021-01-18)

Designer cytokine makes paralyzed mice walk again
To date, paralysis resulting from spinal cord damage has been irreparable. With a new therapeutic approach, scientists from the Department for Cell Physiology at Ruhr-Universität Bochum (RUB) headed by Professor Dietmar Fischer have succeeded for the first time in getting paralyzed mice to walk again. The keys to this are the protein hyper-interleukin-6, which stimulates nerve cells to regenerate, and the way how it is supplied to the animals. (2021-01-15)

T cells linked to myelin implicated in MS-like disease in monkeys
Scientists have uncovered new clues implicating a type of herpes virus as the cause of a central nervous system disease in monkeys that's similar to multiple sclerosis in people. By linking two specific T cells to the loss of myelin, scientists say the new study opens the possibility of developing an antiviral therapy that could be especially useful for newly diagnosed cases of multiple sclerosis. (2021-01-15)

A rift in the retina may help repair the optic nerve
In experiments in mouse tissues and human cells, Johns Hopkins Medicine researchers say they have found that removing a membrane that lines the back of the eye may improve the success rate for regrowing nerve cells damaged by blinding diseases. (2021-01-14)

Study suggests compound protects myelin, nerve fibers
A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord. The new research in a mouse model advances earlier work to develop the compound - known as sobetirome - that has already showed promise in stimulating the repair of myelin. (2021-01-13)

Post-surgical patch releases non-opioid painkiller directly to the wound
A Duke-led team of scientists has developed a bio-compatible surgical patch that releases non-opioid painkillers directly to the site of a wound for days and then dissolves away. The polymer patch provides a controlled release of a drug that blocks the enzyme COX-2 (cyclooxygenase-2,) which drives pain and inflammation. The study appears Jan. 10, 2021 in the Journal of Controlled Release. (2021-01-11)

Engineers find antioxidants improve nanoscale visualization of polymers
Reactive molecules, such as free radicals, can be produced in the body after exposure to certain environments or substances and go on to cause cell damage. Antioxidants can minimize this damage by interacting with the radicals before they affect cells. (2021-01-08)

Tiny wireless device sheds light on combating obesity
In a new study, researchers at Texas A&M University have described a medical device that might help with weight loss and requires a simpler operative procedure for implantation. (2021-01-08)

New strategy to fight botulinum toxin - expert available
Published research shows a new ''Trojan horse'' approach that produces strong antidotal efficacy in treating lethal botulism. (2021-01-06)

Large transporter protein linked to schizophrenia
Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens. Now, Kazumitsu Ueda of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in Japan have provided evidence that mice with disrupted ABCA13 protein demonstrate a hallmark behaviour of schizophrenia. The team investigated ABCA13's functions and published their findings in the Journal of Biological Chemistry. (2020-12-29)

Brain stem cells divide over months
For the first time, scientists at the University of Zurich have been able to observe the way stem cells in the adult brains of mice divide over the course of months to create new nerve cells. Their study shows that brain stem cells are active over a long period, and thus provides new insights that will feed into stem cell research. (2020-12-21)

Machine intelligence accelerates research into mapping brains
Scientists in Japan's brain science project have used machine intelligence to improve the accuracy and reliability of a powerful brain-mapping technique, a new study reports. Their development, published on December 18th in Scientific Reports, gives researchers more confidence in using the technique to untangle the human brain's wiring and to better understand the changes in this wiring that accompany neurological or mental disorders such as Parkinson's or Alzheimer's disease. (2020-12-18)

Cataract surgery in infancy increases glaucoma risk
Children who undergo cataract surgery as infants have a 22% risk of glaucoma 10 years later, whether or not they receive an intraocular lens implant. The findings come from the National Eye Institute (NEI)-funded Infant Aphakic Treatment Study, which today published 10-year follow-up results in JAMA Ophthalmology. NEI is part of the National Institutes of Health. (2020-12-17)

Modulating cells' chloride channels
Daegu Gyeongbuk Institute of Science and Technology (DGIST) researchers gain deeper insight into a cell membrane channel, with potential implications for drug development. (2020-12-16)

Researchers develop new combined process for 3D printing
Chemists at Martin Luther University Halle-Wittenberg (MLU) have developed a way to integrate liquids directly into materials during the 3D printing process. This allows, for example, active medical agents to be incorporated into pharmaceutical products or luminous liquids to be integrated into materials, which allow monitoring of damage. The study was published in ''Advanced Materials Technologies''. (2020-12-16)

Fighting hypertension through electrical impulses
Electrical impulses applied to a particular branch of the vagus nerve could be used in the future to reduce complications of arterial hypertension. These are the results of a research conducted, on animal models, by the Department of Angiocardioneurology and Translational Medicine of the I.R.C.C.S. Neuromed, in Italy, and published in the scientific journal Cell Reports. (2020-12-15)

COVID-19 does not damage auditory system, Tel Aviv University study finds
Since the beginning of the COVID-19 pandemic, there have been reports in the professional literature on possible hearing loss caused by the disease. A new study from Tel Aviv University (TAU), in collaboration with the Galilee Medical Center, finds no evidence of damage to the auditory system as a result of COVID-19 infection. (2020-12-15)

Unexpected discovery leads to better understanding of migraine
Massive ''plumes'' of glutamate, a key neurotransmitter, surging in the brain could help explain the onset of migraine with aura--and potentially a broad swath of neurologic disease, including stroke and traumatic brain injury--according to an international study led by University of Utah Health scientists. (2020-12-14)

Researchers discover clue to how to protect neurons and encourage their growth
Researchers have identified a family of enzymes whose inhibition both protects neurons and encourages their growth, a pathway to potential new treatments for neurodegenerative diseases from Alzheimer's to glaucoma. (2020-12-14)

New biomarker candidate for amyotrophic lateral sclerosis
A research team from the Centre for Protein Diagnostics (Prodi) at Ruhr University Bochum (RUB), in collaboration with scientists from Dresden Technical University, Essen University Hospital and University Hospital Göttingen, has developed a diagnostic tool for the rare neurological disease amyotrophic lateral sclerosis (ALS). The study used the patented immuno-infrared sensor to analyse folding changes of proteins in the cerebrospinal fluid (CSF) of ALS patients after specific binding. (2020-12-09)

Five-minute EEG recordings: a key to the symptoms of Parkinson's disease
Pathological changes related to the disability of Parkinson's patients can already be detected in signals from the scalp without the need to open the skull. Researchers from Leipzig University Hospital and the Max Planck Institute for Human Cognitive and Brain Sciences recently published these new findings in the journal Brain. (2020-12-09)

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