Current Nervous System News and Events

Current Nervous System News and Events, Nervous System News Articles.
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New study: Malaria tricks the brain's defence system
Malaria is one of the most common causes of death in children in Africa. When the parasite builds up in the blood vessels of the brain, it develops into one of the most dangerous forms of the disease, cerebral malaria. Though it wasn't certain if the parasite was able to penetrate the brain tissue, now researchers from the University of Copenhagen have found parasites can do that and have mapped the mechanism they utilise. (2021-01-26)

Nonsurgical treatment for cerebral infarction using wearable wireless ultrasound devices
Korea Institute of Science and Technology(KIST) announced that the research team at the Center for Bionics, led by Dr. Kim Hyungmin, developed a wireless rehabilitation treatment technology for brain nervous system damaged by a stroke by fabricating a wearable, wireless low-intensity focused ultrasound brain stimulator. Additionally, to verify its effectiveness, this brain stimulator was applied to animal models of stroke. (2021-01-19)

Fatty acid may help combat multiple sclerosis
The abnormal immune system response that causes multiple sclerosis (MS) by attacking and damaging the central nervous system can be triggered by the lack of a specific fatty acid in fat tissue, according to a new Yale study. The finding suggests that dietary change might help treat some people with the autoimmune disease. (2021-01-19)

Study suggests compound protects myelin, nerve fibers
A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord. The new research in a mouse model advances earlier work to develop the compound - known as sobetirome - that has already showed promise in stimulating the repair of myelin. (2021-01-13)

SARS-CoV-2 can infect neurons and damage brain tissue, study indicates
Using both mouse and human brain tissue, researchers at Yale School of Medicine have discovered that SARS-CoV-2 can directly infect the central nervous system and have begun to unravel some of the virus's effects on brain cells. The study, published today in the Journal of Experimental Medicine (JEM), may help researchers develop treatments for the various neurological symptoms associated with COVID-19. (2021-01-12)

Oncotarget: HIV +/- patients with lymphoma as a predictor of outcome & tumor proliferation
The Oncotarget author's hypothesis is that ADC values will inversely correlate with Ki-67 expression and that tumors with higher ADC values above the median will have improved OS and PFS (2021-01-11)

Perceiving prosthesis as lighter thanks to neurofeedback
Transmitting sensory signals from prostheses to the nervous system helps leg amputees to perceive prosthesis as part of their body. While amputees generally perceive their prostheses as heavy, this feedback helps them to perceive the prostheses as significantly lighter, ETH researchers have shown. (2021-01-08)

Which came first, sleep or the brain?
In work that could help unravel the origin of sleep, an international team of researchers led by Kyushu University has shown that tiny, water-dwelling hydras not only show signs of a sleep-like state despite lacking central nervous systems but also respond to molecules associated with sleep in more evolved animals. The new results suggest that many sleep-related mechanisms developed before the brain and may have been conserved during the evolution of central nervous systems. (2021-01-08)

Scientists paint multi-color atlas of the brain
Columbia scientists have engineered a coloring technique, known as NeuroPAL (a Neuronal Polychromatic Atlas of Landmarks), which makes it possible to identify every single neuron in the mind of a worm. (2021-01-08)

Drug combination increases susceptibility to chemotherapy in cases of severe neuroblastoma
Researchers at the University of Gothenburg now suggest a possible cure for children with hard-to-treat forms of neuroblastoma using a new combination of drugs. In a new study in the journal Cancer Research, they describe how a two small molecule-based drug combination likely inhibit the tumor's growth. (2021-01-07)

Identifying strategies to advance research on traumatic brain injury's effect on women
Analysis from a workshop convened by the National Institute of Neurological Disorders and Stroke (NINDS) in 2017 reveals gaps in and opportunities for research to improve understanding of the effects of traumatic brain injury (TBI) in women. A new paper in the Journal of Head Trauma Rehabilitation summarizes and updates the findings presented during the 'Understanding Traumatic Brain Injury in Women' workshop and provides strategies for advancing research efforts in this area. NINDS is part of the National Institutes of Health. (2021-01-06)

Researchers illuminate neurotransmitter transport using X-ray crystallography and molecular simulations
Scientists from the MIPT Research Center for Molecular Mechanisms of Aging and Age-Related Diseases have joined forces with their colleagues from Jülich Research Center, Germany, and uncovered how sodium ions drive glutamate transport in the central nervous system. Glutamate is the most important excitatory neurotransmitter and is actively removed from the synaptic cleft between neurons by specialized transport proteins called excitatory amino acid transporters (EAATs). (2020-12-21)

Researchers explore why some MS patients experience seizures
A research team at the UC Riverside School of Medicine has identified a pathway involving astrocytes, a class of central nervous system support cells, that could shed light on why seizures happen in a subset of multiple sclerosis, or MS, patients. The finding improves scientific understanding of how seizures arise in MS and could provide the foundation for better therapies to manage treatment-resistant seizures in MS and other brain diseases. (2020-12-21)

Obstructive sleep apnoea puts a strain on the heart, too
Longer nocturnal respiratory events in patients with obstructive sleep apnoea (OSA) cause higher immediate heart rate variability, and greater changes in beat-to-beat intervals are associated with reduced daytime alertness, according to new research from the University of Eastern Finland. (2020-12-10)

COVID-19 may also invade the central nervous system, cause neurological illnesses
COVID-19 is known primarily as a respiratory disease, with symptoms that include cough, shortness of breath, and, in severe cases, acute respiratory distress syndrome and pneumonia. Now, Cleveland Clinic researchers note in a recent review that infection with the coronavirus may also affect the central nervous system and cause corresponding neurological disorders, including ischemic stroke, encephalitis, encephalopathy and epileptic seizures. According to the review published in Cells, the symptoms of COVID-19-related neurological manifestations include dizziness, headache, a loss of consciousness and ataxia. (2020-12-10)

Damage to brain cells reverberates to 'bystander' cells, study finds
Injury or disease that afflicts a relatively small number of brain cells causes a chain reaction that stops activity across a vast network of neural circuits, according to new research. The study may help to explain why people can suffer from temporary but severe loss of cognitive function in cases of traumatic brain injury or disease. (2020-12-08)

New fundamental knowledge of the 'abdominal brain'
Researchers at Karolinska Institutet have succeeded in mapping the neuron types comprising the enteric nervous system in the intestine of mice. The study, which is published today in the scientific journal Nature Neuroscience, also describes how the different neurons form during fetal development, a process that follows different principles to brain neurons. (2020-12-07)

Birth defects linked to greater risk of cancer in later life
People born with major birth defects face a higher risk of cancer throughout life, although the relative risk is greatest in childhood and then declines, finds a study published by The BMJ today. (2020-12-02)

Scientists identify new genetic MND risk factor in junk DNA
Researchers from the University of Sheffield have identified a new genetic risk factor for Motor Neurone Disease (MND). (2020-12-01)

How SARS-CoV-2 reaches the brain
Using post-mortem tissue samples, researchers from Charité - Universitätsmedizin Berlin have studied the mechanisms by which the novel coronavirus can reach the brains of patients with COVID-19. The results show that SARS-CoV-2 enters the brain via nerve cells in the olfactory mucosa. For the first time, researchers have been able to produce electron microscope images of intact coronavirus particles inside the olfactory mucosa. (2020-11-30)

New mechanism of pain control revealed
Researchers have identified a unique population of astrocytes in the dorsal horn of the spinal cord of mice that produces pain hypersensitivity when activated by neurons carrying signals down from the brain. The findings indicate that the role of descending neurons in controlling spinal pain transmission is not limited to suppression and point to this group of astrocytes as a new target for enhancing the effect of chronic pain treatments. (2020-11-25)

Breaking the skill limit, pianists attain more delicate touch
Japanese scientists discovered a training method to further improve the delicate touch of pianists by optimizing the method rather than increase the amount of training. They developed a system that freely controls the weight of piano keys using a haptic device, which enables to control the strength and direction of the force. The results of experiments showed that enhancing the somatosensory function of fingertips with AHT could improve the accuracy of keystrokes. (2020-11-25)

Gut-brain axis influences multiple sclerosis
A Basel-led international research team has discovered a connection between the intestinal flora and sites of inflammation in the central nervous system in multiple sclerosis. A specific class of immune cell plays a central role in this newly identified gut-brain axis. The discovery could pave the way for new treatments for MS that target the intestinal flora. (2020-11-20)

Lovestruck by oxytocin! Novel roles of the hormone in controlling male sexual function
Hormones are the master regulators of sexual functions in mammals. The hormone oxytocin has a well-established role in social bonding, sexual function, maternal instinct, nursing, and lactation. Researchers from Okayama University have now explored the roles of oxytocin in male sexual function for the first time. Findings from the study suggest that oxytocin-mediated control of male sexual function via the spinal cord may in fact be instrumental in treating erectile dysfunction. (2020-11-18)

Learning a new language changes the brain's division of labor
Learning a language later in life changes how the two halves of the brain contribute. As skills improve, language comprehension changes hemisphere specialization, but production does not, according to new research published in JNeurosci. (2020-11-17)

Parasite infection discovery could assist mental health treatments
New research into how a common parasite infection alters human behaviour could help development of treatments for schizophrenia and other neurological disorders. T. gondii currently infects 2.5 billion people worldwide and causes the disease Toxoplasmosis. (2020-11-16)

Mediterranean diet helps reduce effects of stress in animal model, study shows
Even before the pandemic and the presidential election, Americans reported some of the highest perceived levels of stress in the world, according to the American Psychological Association. Not only does stress have negative effects on work and personal relationships, it also increases the risk of many chronic conditions, such as heart disease and Alzheimer's disease, and is associated with higher mortality rates. (2020-11-16)

Changes to the brain's reward system may drive overeating in mice
A combination of innate differences and diet-induced changes to the reward system may predispose some mice to overeat, according to research recently published in JNeurosci. (2020-11-16)

Link between Alzheimer's disease and gut microbiota is confirmed
In recent years, the scientific community has suspected that the gut microbiota plays a role in the development of the disease. A team from the University and the Hospital of Geneva the National Research and, University and IRCCS SDN Research Center of Naples, confirm the correlation, in humans, between an imbalance in the gut microbiota and the development of amyloid plaques in the brain, which are at the origin of Alzheimer's disease. (2020-11-13)

Brain metastases cause severe brain damage that can be inhibited by treatment
By using a specific treatment to override this activation, the researchers were able to return cerebrovascular flow to healthy levels. This improvement in blood flow around the metastases can limit the neurological deterioration associated with the progression of this disease and improve the otherwise poor life expectancy of these patients. (2020-11-12)

Yale scientists identify protein that protects against Lyme
Yale researchers have discovered a protein that helps protect hosts from infection with the tick-borne spirochete that causes Lyme Disease, a finding that may help diagnose and treat this infection, they report Nov. 11 in the journal PLOS Pathogens. (2020-11-11)

Potential brain damage marker could guide assessment and treatment of strokes
A team of researchers has discovered that a protein found in the nervous system can predict the severity of brain damage and long-term outcomes in patients who have suffered a stroke. (2020-11-11)

Vaccine shows promise against herpes virus
A genetically edited form of a herpes simplex virus has outperformed a leading vaccine candidate in a new study published in Nature Vaccines. When challenged with a virulent strain of the sexually transmitted HSV-2, vaccinated guinea pigs displayed fewer genital lesions, less viral replication and less of the viral shedding that most readily spreads infection. (2020-11-06)

Technique to regenerate optic nerve offers hope for future glaucoma treatment
Scientists have used gene therapy to regenerate damaged nerve fibres in the eye, in a discovery that could aid the development of new treatments for glaucoma, one of the leading causes of blindness worldwide. (2020-11-05)

Surprising insights into the role of autophagy in neuron
Autophagy protects our neurons in the brain, but for entirely different reasons than previously assumed, as researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and Charité in Berlin have shown. When the scientists used a genetic trick to switch off autophagy-mediated ''cellular waste disposal'', they found elevated levels of the endoplasmic reticulum, which acts, among other functions, as a calcium store. This leads to elevated neurotransmitter release and, ultimately, to fatal neuronal hyperexcitability. (2020-11-05)

Nervous systems of insects inspire efficient future AI systems
Study explores functions of fruit fly's nervous system in food seeking / results valuable for the development and control of artificial intelligence. (2020-11-05)

Delirium could be an early marker of COVID-19
Delirium accompanied by fever could be an early symptom of COVID-19. This is the main conclusion drawn by a scientific research review carried out by researchers from the Universitat Oberta de Catalunya (UOC) and published in the open access Journal of Clinical Immunology and Immunotherapy, which highlights the fact that, together with the loss of the senses of taste and smell and headaches that occur in the days prior to the manifestation of coughing and breathing difficulties, some patients also develop delirium. (2020-11-04)

The gut trains the immune system to protect the brain
The membranes surrounding our brains are in a never-ending battle against deadly infections, as germs constantly try to elude watchful immune cells and sneak past a special protective barrier called the meninges. In a study involving mice and human autopsy tissue, researchers at the National Institutes of Health and Cambridge University have shown that some of these immune cells are trained to fight these infections by first spending time in the gut. (2020-11-04)

Chikungunya may affect central nervous system as well as joints and lungs
Investigation conducted by international group of researchers showed that chikungunya virus can cause neurological infections. Risk of death in subacute phase is higher for patients with diabetes and significant for young adults. (2020-11-04)

Hormone differences
During birth, hormones in the body surge in both mother and baby, sent along by the nervous system. These stress hormones are there to spur delivery and to help a baby adapt to living outside the womb. A new study finds how one is born can have an effect on the amount of stress hormones released at the time of delivery. For example, vaginal delivery had the highest presence of birth signaling hormones. (2020-11-04)

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