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Genetic factors contributing to 'strabismus' -- or misaligned eyes
Researchers at the National Institute of Genetics in Japan discovered a key gene for generating eye movements. (2018-08-07)
UCLA bioengineers use magnetic force to manage pain
UCLA bioengineers have demonstrated that a gel-like material containing tiny magnetic particles could be used to manage chronic pain from disease or injury. (2018-08-07)
Research Brief: UMN Medical School researchers study how cues drive our behavior
Recent research published in Nature Neuroscience by University of Minnesota Medical School neuroscientist Benjamin Saunders, PhD, uses a Pavlovian model of conditioning to see if turning on a light -- a simple cue -- just before dopamine neurons were activated could motivate action. (2018-08-07)
Mice individuality is influenced by their relations
Individuality exists in all animals, and a number of factors shape it over time. (2018-08-06)
Enzyme helps build motor that drives neuron death
The process, discovered in the axons of neurons, is implicated in Alzheimer's, amyotrophic lateral sclerosis, traumatic brain injury and other diseases or injuries to the nervous system. (2018-08-06)
VIP neurons shift daily rhythms
Neurons in the brain's master clock that adjust their activity in response to light have a key role in the resetting of an animal's daily cycle, finds a study of male and female mice published in JNeurosci. (2018-08-06)
Locusts help uncover the mysteries of smell
By looking into the brains of locusts, researchers in the School of Engineering & Applied Science at Washington University in St. (2018-08-03)
UMN Medical School researchers study how cues drive our behavior
Recent research published in Nature Neuroscience by University of Minnesota Medical School neuroscientist Benjamin Saunders, PhD, uses a Pavlovian model of conditioning to see if turning on a light -- a simple cue -- just before dopamine neurons were activated could motivate action. (2018-08-02)
Fecal deposits reveal the fruit fly's pheromone flag
Fruit flies have a rich language of smell messages that they exchange, but now their secret is out. (2018-08-02)
Common evolutionary origins between vertebrates and invertebrates revealed
Tsukuba-centered researchers elucidated the evolutionary origins of placodes and neural crests, which are defining features of vertebrates, through lineage tracing and genetic analysis in Ciona intestinalis, a marine invertebrate animal. (2018-08-01)
Study: Alzheimer's drug may stop disease if used before symptoms develop
Biologists have gained new understanding of how Alzheimer's disease begins, and how it might be halted using a current medication. (2018-08-01)
Gene therapy restores sense of smell in mice
Re-expressing a protein critical for the detection and perception of odors restores function of the olfactory system in a genetic mouse model of lost hair-like cellular structures known as cilia, according to research published in JNeurosci. (2018-07-30)
What keeps the brain awake
A study of fruit flies has identified a pathway in the brain that keeps the animals from falling asleep during the day. (2018-07-30)
Alzheimer's risk gene impairs development of new neurons in mice
Scientists have taken a step closer to understanding how the strongest known genetic risk factor for Alzheimer's disease (AD) contributes to memory impairment. (2018-07-30)
Microfluidic system incorporates neuroinflammation into 'Alzheimer's in a dish' model
Building on their development of the first culture system to replicate fully the pathology behind Alzheimer's disease, a Massachusetts General Hospital research team has now produced a system that includes neuroinflammation, the key biological response that leads to the death of brain cells. (2018-07-30)
Luxembourgish researchers predict cell conversion factors
Thanks to a newly developed computational method, Luxembourg researchers can accurately predict how one subpopulation of cells can be converted into another. (2018-07-27)
Traumatic brain injury: Discovery of two molecules could lead to new drug treatments
After 10 years of research, a Rutgers-led team of scientists has identified two molecules that protect nerve cells after a traumatic brain injury and could lead to new drug treatments. (2018-07-26)
Researchers discover system that could reduce neurodegeneration in Huntington's disease
The neuroscientist Dr David Vilchez and his team at CECAD, the University of Cologne's Cluster of Excellence for Aging Research, have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease. (2018-07-26)
Electricity sparks neuronal diversity during brain development
To understand how neuronal circuits emerge during development, researchers from UNIGE investigated what enables neuronal stem cells to generate successive subtypes of neurons as the embryo grows. (2018-07-26)
NIST chip lights up optical neural network demo
Researchers at the National Institute of Standards and Technology (NIST) have made a silicon chip that distributes optical signals precisely across a miniature brain-like grid, showcasing a potential new design for neural networks. (2018-07-26)
Unconventional connections: How inhibition hones cortical selectivity
Understanding how neural circuits build response selectivity poses an enormous challenge since a single neuron receives thousands of synaptic inputs derived from other neurons and these inputs can differ in their response properties. (2018-07-25)
Widespread connections among neurons help the brain distinguish smells
Organization--or lack of it--in brain's piriform cortex allows us to differentiate one smell from another. (2018-07-24)
Study provides insight into how dying neurons control eating behaviors of the brain microglia
Aberrant clearance activity of microglia in particular brain regions leads to changes associated with neurodegenerative diseases. (2018-07-23)
A promising approach to translational research on stem cells for Parkinson's disease
A major factor underlying Parkinson's Disease (PD) pathology is the loss of dopamine neurons in the substantia nigra, and thus current therapies often aim to restore dopamine signaling. (2018-07-23)
How experience changes basics of memory formation
We know instinctively that our experiences shape the way we learn. (2018-07-23)
Giant neurons in the brain may play similarly giant role in awareness and cognition
Scientists find that certain neurons release nitric oxide onto nearby blood vessels, and potentially use this mechanism to control awareness in the brain. (2018-07-23)
A peek into the interplay between sleep and wakefulness
The ventrolateral preoptic nucleus (VLPO) in the brain plays a critical role in the initiation and maintenance of sleep, while the lateral posterior part of the hypothalamus contains neuronal populations implicated in maintenance of arousal. (2018-07-20)
Complete fly brain imaged at nanoscale resolution
Scientists at HHMI's Janelia Research Campus have taken detailed pictures of the entire brain of an adult female fruit fly using transmission electron microscopy. (2018-07-19)
Neurons can carry more than one signal at a time
New research from Duke University shows that neurons in the brain can carry two signals at once, using a strategy similar to multiplexing in telecommunications. (2018-07-18)
Novel botulinum toxin compound relieves chronic pain
A modified form of botulinum toxin gives long-lasting pain relief in mice without adverse effects and, in time, could replace opioid drugs as a safe and effective way of treating chronic pain, according to research by UCL, the University of Sheffield and the Hospital for Sick Children, Toronto. (2018-07-18)
In rats, perinatal exposure to phthalates impairs brain structure and function
Rats exposed in the womb and during lactation to plasticizing chemicals known as phthalates had fewer neurons and synapses than those that were not exposed, researchers report in a new study. (2018-07-18)
Researchers identify brain area linked to motivational disruptions in binge eating
Scientists at Rutgers Brain Health Institute have discovered that a small group of brain cells in the hypothalamus called 'orexin' neurons could be a promising target for medications for controlling binge eating episodes in individuals with obesity. (2018-07-17)
Study: Protein found to be key component in irregularly excited brain cells
In a new study in mice, researchers have identified a key protein involved in the irregular brain cell activity seen in autism spectrum disorders and epilepsy. (2018-07-17)
Fruit fly mating driven by a tweak in specific brain circuit
According to a new National Institutes of Health-funded study, it is not destiny that brings two fruit flies together, but an evolutionary matchmaker of sorts that made tiny adjustments to their brains' mating circuits, so they would be attracted to one another while rejecting advances from other, even closely-related, species. (2018-07-16)
Plastic chemical linked to smaller prefrontal cortex, reduced cognitive ability in rats
Adult rats that had been exposed before birth and during nursing to a mixture of chemicals found in a wide range of consumer products have a smaller medial prefrontal cortex (mPFC) and perform worse on an attention-switching task than rats not exposed to the chemicals early in life. (2018-07-16)
Synapse-specific plasticity governs the identity of overlapping memory traces
Each memory is stored in a specific population of neurons called engram cells. (2018-07-13)
The VIPs of the nervous system
Biologists at Washington University in St Louis unlocked a cure for jet lag in mice by activating a small subset of the neurons involved in setting daily rhythms. (2018-07-12)
Deep in the fly brain, a clue to how evolution changes minds
A new study sheds light on the mystery of how evolution tweaks the brain to shape behavior. (2018-07-11)
Why are neuron axons long and spindly? Study shows they're optimizing signaling efficiency
A team of bioengineers at UC San Diego has answered a question that has long puzzled neuroscientists, and may hold a key to better understanding the complexities of neurological disorders: Why are neuron axons designed the way they are? (2018-07-11)
Scientists trigger hot flashes in female and male mice
By activating a single type of neuron, scientists triggered hot-flash-like symptoms in mice. (2018-07-10)
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