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Current Neurosurgery News and Events, Neurosurgery News Articles.
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Artificial intelligence-based algorithm for intensive care of traumatic brain injury
A recent Finnish study, published in Scientific Reports, presents the first artificial intelligence (AI) based algorithm that may be utilized in the intensive care unit for treating patients with severe traumatic brain injury. The project is a collaborative project between three Finnish university hospitals: Helsinki University Hospital, Kuopio University Hospital and Turku University Hospital. (2019-11-27)

Changes in pupils after asymptomatic high-acceleration head impacts indicate changes in brain function
Researchers used quantitative pupillometry to detect pupillary changes in high-school athletes after they sustained a high-acceleration head impact. These pupillary changes, indicative of changes in brain function, were evident even when the athletes had no discernible symptoms. (2019-11-26)

Neurosurgery in Brazilian Amazon is possible
Low- and middle-income countries in remote locations with little access to care can create sustainable neurosurgical programs by recruiting and training young, local doctors, according to a Rutgers study. Published in the journal World Neurosurgery, the study analyzed the effectiveness over the past 20 years of a successful neurosurgical department, its residency program, an international residency rotation and a medical student exchange program, all in Santarém, a poor, remote region of Brazil in the Amazon rainforest. (2019-11-10)

Study reveals how brain injury can lead to post-traumatic stress disorder
Post-traumatic stress disorder in U.S. military members frequently follows a concussion-like brain injury. Until now, it has been unclear why. A UCLA team of psychologists and neurologists reports that a traumatic brain injury causes changes in a brain region called the amygdala; and the brain processes fear differently after such an injury. (2019-11-04)

Can aspirin decrease the rate of intracranial aneurysm growth?
Researchers investigated whether aspirin can aid in the prevention of intracranial aneurysm rupture by hindering aneurysm growth. The researchers identified 146 patients harboring multiple intracranial aneurysms, five millimeters or less in diameter, that had been observed for at least five years. In this set of patients, the researchers found an association between aspirin use and a decreased rate of aneurysm growth. Growth is important in intracranial aneurysms because it increases the risk of aneurysm rupture. (2019-10-29)

Electrical stimulation aids in spinal fusion
Spine surgeons in the U.S. perform more than 400,000 spinal fusions each year as a way to ease back pain and prevent vertebrae in the spine from wiggling around and doing more damage. However, reports estimate that on average some 30% of these surgeries fail to weld these vertebrae into a single bone, causing continued back pain. (2019-10-23)

Protein in blood protects against neuronal damage after brain hemorrhage
Patients who survive a cerebral hemorrhage may suffer delayed severe brain damage caused by free hemoglobin, which comes from red blood cells and damages neurons. Researchers at the University of Zurich and the UniversityHospital Zurich have now discovered a protective protein in the body called haptoglobin, which prevents this effect. (2019-10-21)

Glowing particles in the blood may help diagnose and monitor brain cancer
A chemical that has improved surgeries for brain cancer by making tumor cells fluorescent may also help doctors safely diagnose the disease and monitor its response to treatment. (2019-10-15)

The effectiveness of electrical stimulation in producing spinal fusion
Researchers from The Johns Hopkins University School of Medicine performed a systematic review and meta-analysis of published data on the effect of electrical stimulation therapies on spinal fusion. They found significant improvement overall in the rates of bone fusion following a course of electrical stimulation in both preclinical (animal) and clinical (human) studies. (2019-10-08)

The 'Goldilocks' principle for curing brain cancer
University of Minnesota Medical School researchers found that a stable body temperature holds the key to awakening the body's immune response to fight off brain cancer. (2019-10-04)

Golden ratio observed in human skulls
The Golden Ratio, described by Leonardo da Vinci and Luca Pacioli as the Divine Proportion, is an infinite number often found in nature, art and mathematics. It's a pattern in pinecones, seashells, galaxies and hurricanes. (2019-10-03)

Stem cell studies offer hope for childhood neurological condition
Two new studies by an international team of researchers report progress in using stem cells to develop new therapies for Pelizaeus-Merzbacher disease (PMD), a rare genetic condition affecting boys that can be fatal before 10 years of age (2019-10-03)

Exploring the brain in a new way: WVU researcher records neurons to understand cognition
Whether we're searching for Waldo or our keys in a room of clutter, we tap into a part of the frontal region of the brain when performing visual, goal-related tasks. Some of us do it well, whereas for others it's a bit challenging. One West Virginia University researcher set out to investigate why, and what specifically this part of the brain, called the pre-supplementary motor area, does during searching. (2019-10-01)

Deep brain stimulation for refractory severe tinnitus
Researchers investigated the safety and efficacy of deep brain stimulation in the treatment of refractory severe tinnitus in a small group of patients. They found the procedure to be safe and the results to be encouraging. (2019-09-24)

New twist on old surgical technique helps repair patient's skull base
A Rutgers-led team of surgeons developed a groundbreaking procedure based on a paramedian forehead flap, a century-old plastic surgery technique, to save the life of a patient who suffered complications following the removal of a cancerous tumor inside his skull. This method can help other patients with similar complications, for whom all other solutions have failed. (2019-07-31)

Immune therapy takes a 'BiTE' out of brain cancer
Massachusetts General Hospital investigators have created a new method that could make immune therapy more effective again brain tumors and expand its use against other types of solid tumors. (2019-07-24)

Artificial nose identifies malignant tissue in brain tumours during surgery
An artificial nose developed at Tampere University, Finland, helps neurosurgeons to identify cancerous tissue during surgery and enables the more precise excision of tumours. (2019-06-14)

Which brain hemorrhage patients have treatable underlying conditions
A new study identifies patients more likely to have underlying lesions from brain-bleeds, a finding that could help doctors treat the condition more rapidly. (2019-06-03)

Microbes on explanted pedicle screws: Possible cause of spinal implant failure
In this paper, the authors demonstrate a significant association between pedicle screw loosening and the presence of low-virulent pathogens on spinal implants. (2019-05-28)

New evidence supports surgery for rare type of brain lymphoma
Through a systematic review of published studies going back 50 years, Johns Hopkins Medicine researchers say they have identified a distinct subtype of primary central nervous system (PCNS) lymphoma that should be considered for surgical removal, suggesting a major shift in how this type of tumor is evaluated and managed. (2019-05-28)

New brain tumor imaging technique uses protein found in scorpion venom
A novel imaging technique that uses a synthesized form of scorpion venom to light up brain tumors has shown promise in a clinical trial. The imaging system enables neurosurgeons to better see malignant growths that often are difficult to fully eliminate. The new imaging technique that was studied uses a special high-sensitivity near-infrared camera developed at Cedars-Sinai, along with the imaging agent tozuleristide, or BLZ-100, developed by Blaze Bioscience, Inc. (2019-05-09)

Simple test can indicate prolonged symptoms following pediatric sports-related concussion
Researchers from Children's Hospital Colorado and the University of Colorado School of Medicine in Aurora, Colorado, have found that abnormal performance on the Romberg balance test can indicate that children and adolescents will experience prolonged symptoms following sports-related concussion. (2019-04-16)

Awake lumbar interbody fusion
This article provides the reader with a glimpse of how effective lumbar surgery in select patients can be when performed without general anesthesia, open surgery, or a long convalescence in the hospital. (2019-04-01)

Enhanced recovery after spine surgery: 15 new articles in the April Neurosurgical Focus
The April issue of Neurosurgical Focus contains 15 new articles on the principles of enhanced recovery after surgery and how these principles relate to spine surgery. (2019-04-01)

Deep brain stimulation provides sustained relief for severe depression
Patients suffering from severe, treatment-resistant depression can benefit not only acutely but also the long-term from deep brain stimulation, as researchers from the Medical Center -- University of Freiburg and their colleagues from the University Hospital Bonn demonstrate in a current study. (2019-03-19)

Less-invasive procedure helps surgeons pinpoint epilepsy surgical candidates
A minimally invasive procedure to determine whether patients with drug-resistant epilepsy are candidates for brain surgery is safer, more efficient, and leads to better outcomes than the traditional method, according to new research by The University of Texas Health Science Center at Houston (UTHealth). (2019-03-07)

When it comes to hearing words, it's a division of labor between our brain's two hemispheres
Scientists have uncovered a new 'division of labor' between our brain's two hemispheres in how we comprehend the words and other sounds we hear -- a finding that offers new insights into the processing of speech and points to ways to address auditory disorders. (2019-03-04)

Traumatic brain injury and kids: New treatment guidelines issued
To help promote the highest standards of care, and improve the overall rates of survival and recovery following TBI, a panel of pediatric critical care, neurosurgery and other pediatric experts today issued the third edition of the Brain Trauma Foundation Guidelines for the Management of Pediatric Severe TBI. (2019-03-01)

Recent advances in spina bifida care extend life and improve quality of life
Spina bifida (myelomeningocele) is the most common, permanently disabling birth defect compatible with life. In a collection of articles, published in the Journal of Pediatric Rehabilitation Medicine, experts describe important advances made in the care of spina bifida patients that extend life and improve quality of life. (2019-02-28)

Muscle gene mutations implicated in human nasal/sinus cancer
By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic change -- one in a gene involved in muscle formation -- in five of the tumors. (2019-02-27)

Food allergies and multiple sclerosis: study reveals a new link
Investigating the correlation between allergy and inflammatory disease activity, a team of investigators from Brigham and Women's Hospital has found new evidence connecting food allergies and relapses of multiple sclerosis. (2019-02-19)

New research findings could be key to improving outcomes for some brain cancers
Researchers from the University of Michigan Rogel Cancer Center have found that a genetic mutation seen in about half of all brain tumors produces a response that prevents radiation treatment from working. Altering that response using FDA-approved drugs restores tumors' sensitivity to radiation therapy, extending survival in mice. (2019-02-13)

Training the prescriber
The authors assess the effect of a mandatory educational program and new institutional prescriber guidelines on the behavior of physicians who prescribe opioid medications following lumbar surgery. (2019-02-05)

Golf as a contact sport?
The authors describe how the modern golfer repeatedly experiences minor traumatic injuries to the spine, which over time can result in a pathogenic process termed 'repetitive traumatic discopathy.' (2019-02-05)

Medical experts restore movement and autonomic function in patients with complete paralysis
There are more than 290,000 people estimated to be living in the United States with a spinal cord injury. Previously, it has been shown that it is possible to restore some function to young and healthy patients within a few years of injury. Now, researchers show spinal cord stimulation can immediately restore some voluntary movement and autonomic functions such as cardiovascular, bowel, and bladder years after a paralyzing injury without any significant rehabilitation. (2019-01-31)

Penn's 'enhanced recovery' protocol reduces opioid use in spinal surgery patients
A novel 'Enhanced Recovery After Surgery' (ERAS) protocol developed by Penn Medicine for patients undergoing spinal and peripheral nerve surgery significantly reduced opioid use. The new study published in the Journal of Neurosurgery: Spine showed that when an ERAS protocol was employed, fewer patients needed pain medications one month after surgery. (2019-01-25)

The hitchhiker's guide to defeating glioblastoma
A team of investigators at Brigham and Women's Hospital and Harvard Medical School has begun looking at microRNAs in an entirely new way. Their approach has shown promising results in preclinical models, increasing survival in a murine model of glioblastoma by five-fold when combined with chemotherapy. The team's results are published in Nature Communications. (2019-01-25)

MD Anderson study shows FGL2 protein may be an effective target for glioblastoma
Glioblastoma (GBM) does not attract robust T cell immune responses. FGL2 is highly expressed in GBM and when present in tumor cells, controls a specialized group of dendritic cells which activates T cells. (2019-01-25)

Quality of life in adolescents recovering from sports-related concussion or fracture
Researchers studied health-related quality of life in adolescents with sports-related concussion or extremity fracture during their recovery periods. (2019-01-15)

Helping make brain surgery safer
A biopsy needle that can help surgeons identify and avoid blood vessels in the brain during surgery has undergone initial tests in humans. (2018-12-19)

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