Current Neutrophils News and Events

Current Neutrophils News and Events, Neutrophils News Articles.
Sort By: Most Relevant | Most Viewed
Page 1 of 14 | 526 Results
Antibody response may drive COVID-19 outcomes
Researchers at the Ragon Institute of MGH, MIT and Harvard and Massachusetts General Hospital show that levels of specific antibodies developed in the immune response may influence COVID-19 outcomes in both children and adults. (2021-02-18)

Mast cells: Sentinels and high-speed messengers of the immune defense
A team of scientists at the Institute for Molecular and Clinical Immunology at the Otto-von-Guericke University Magdeburg unravels a crucial mechanism of cell-cell-communication during the defense against pathogens. (2021-02-04)

Aging-US: Anserine protected against cognitive decline
The Aging-US results suggest that anserine protects elderly persons with MCI from cognitive declines by suppressing MPO-mediated neuroinflammatory responses. (2021-02-02)

Study reveals new insights into the link between sunlight exposure and kidney damage
A new collaborative study from researchers at the Geisel School of Medicine at Dartmouth and the University of Washington and published in the Proceedings of the National Academy of Sciences (PNAS), reveals unexpected insights into how skin exposure to ultraviolet light can worsen clinical symptoms in autoimmune diseases such as lupus. (2021-01-21)

Scientists discover link between nicotine and breast cancer metastasis
Scientists at Wake Forest School of Medicine have found that nicotine promotes the spread of breast cancer cells into the lungs. (2021-01-20)

New research finds ginger counters certain autoimmune diseases in mice
The main bioactive compound of ginger root lowers autoantibody production and helps halt disease progression in mice with antiphospholipid syndrome and lupus. (2021-01-06)

White blood cells may cause tumor cell death -- but that's not good news
White blood cells are part of many immune system responses in the human body. New research shows that a specific type of those cells may cause brain cancer tissues to die -- but that's not good news, according to researchers at Penn State College of Medicine. They said that higher amounts of this tissue death have been associated with poor survival in patients with aggressive glioblastomas, a deadly type of brain cancer that is common in adults. (2020-12-07)

Researchers discover new particle in the blood of septic patients
Researchers at La Jolla Institute for Immunology (LJI) have found that people with sepsis have never-before-seen particles in their blood. The scientists are the first to show that these particles, called elongated neutrophil-derived structures (ENDS), break off of immune cells and change their shape as they course through the body. (2020-12-04)

Medicine-carriers made from human cells can cure lung infections
Scientists used human white blood cell membranes to carry two drugs, an antibiotic and an anti-inflammatory, directly to infected lungs in mice. The nano-sized drug delivery method successfully treated both the bacterial growth and inflammation in the mice's lungs. The study shows a potential new strategy for treating infectious diseases, including COVID-19. (2020-12-03)

What makes psoriasis sore: Novel role of immune system in the disease
More than 130 million people around the globe suffer from psoriasis vulgaris, a chronic condition characterized by skin inflammation, scales, and dry patches. However, its pathology is not fully clear. In a recent study, dermatology researchers from Japan have uncovered a complex cellular mechanism responsible for the onset of psoriasis and highlighted potential therapeutic targets for future treatment. (2020-12-03)

Stress hormones can reawaken sleeping tumor cells, raising risk of cancer recurrence
Stress hormones and immune cells called neutrophils may contribute to the recurrence of tumors years after treatment by awakening dormant cancer cells, suggests a study of mice and data from 80 patients with lung cancer. (2020-12-02)

RUDN University biologist found sex differences in inflammatory reactions in rat pups
A biologist from RUDN University studied the development of the immune response in prepubertal male and female animals. According to her, the severity and mortality of infectious and inflammatory diseases at this age depend not on the sex hormones, but mainly on the chromosome set or karyotype. (2020-11-09)

Cancer researchers train white blood cells to attacks tumor cells
Scientists at the National Center for Tumor Diseases Dresden (NCT/UCC) and Dresden University Medicine, together with an international team of researchers, were able to demonstrate that certain white blood cells, so-called neutrophil granulocytes, can potentially - after completing a special training program -- be utilized for the treatment of tumors. The scientists published their results in the renowned specialist journal Cell. (2020-11-06)

Unraveling the genetic determinants of small vessel vasculitis
Researchers from the University of Tsukuba have shown that the single-nucleotide variants of TERT and DSP, which promote risk for idiopathic pulmonary fibrosis (IPF), are significantly associated with susceptibility to microscopic polyangiitis and myeloperoxidase-ANCA associated vasculitis. Interestingly, there was no clear link to the severe complication interstitial lung disease (ILD). These findings suggest a shared genetic susceptibility between IPF and ANCA-associated vasculitides that may be independent of ILD risk. (2020-11-03)

New cause of COVID-19 blood clots identified
A new study reveals that COVID-19 triggers production of antibodies circulating through the blood, causing clots in people hospitalized with the disease. (2020-11-02)

Priming the immune system to attack cancer
Research by an international team, co-led by the University of Pennsylvania's George Hajishengallis, showed how immune ''training'' transforms innate immune cells to target tumors. The findings could inform new approaches to cancer immunotherapy or even strategies for preventing tumor growth. (2020-10-29)

The unexpected repair function of neutrophils
Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered that neutrophils, the most abundant cells of the innate immune system, have many more functions in the body than previously thought. (2020-10-23)

Medical minds meet to develop novel treatment for one patient's immune system defect
A young woman who had been hospitalized for three months straight due to debilitating, recurrent infections with no apparent underlying cause was finally able to go home thanks to a Massachusetts General Hospital (MGH) team who put their heads together, discovered a root of the problem, and developed a novel treatment strategy just for her. (2020-10-22)

Mechanism linking gum disease to heart disease, other inflammatory conditions discovered
The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind that association has, until now, remained a mystery. This month, a team of scientists and clinicians led by the University of Toronto's Faculty of Dentistry say they've found the reason why -- and it's related to the body's own hyperactive immune response. The findings were published in October in the Journal of Dental Research. (2020-10-20)

Metoprolol: an old drug with unique cardioprotective properties
A a study carried out by scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) shows that the cardioprotective effect of metoprolol during a heart attack is not shared by other beta-blockers commonly administered by intravenous injection, such as atenolol and propranolol. (2020-10-09)

Cells sacrifice themselves to boost immune response to viruses
Whether flu or coronavirus, it can take several days for the body to ramp up an effective response to a viral infection. New research appearing in the journal Nature Immunology describes how different cells in the immune system work together, communicate, and - in the case of cells called neutrophils - bring about their own death to help fight off infections. The findings could have important implications for the development of vaccines and anti-viral therapies. (2020-09-30)

Biomarker predicts who will have severe COVID-19
KAIST researchers have identified key markers that could help pinpoint patients who are bound to get a severe reaction to COVID-19 infection. This would help doctors provide the right treatments at the right time, potentially saving lives. The findings were published in the journal Frontiers in Immunology on August 28. (2020-09-17)

Researchers identify key role of immune cells in brain infection
Researchers at the University of Liverpool have identified the specific type of immune cell that induces brain inflammation in herpes simplex virus (HSV) encephalitis. Crucially, they have also determined the signalling protein that calls this immune cell into the brain from the bloodstream. The findings, published in Cell Reports, could aid the development of targeted treatments for the brain infection, which is the most common cause of viral encephalitis worldwide. (2020-09-15)

A new approach to understanding the biology of wound healing
Researchers use discarded wound dressings as a novel and non-invasive way to study the mechanisms that promote healing. (2020-09-15)

DNA webs may drive lung pathology in severe COVID-19
Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental Medicine (JEM). The research, conducted by independent groups in Belgium and Brazil, suggests that blocking the release of these DNA webs could be a new therapeutic target for the management of severe forms of COVID-19. (2020-09-14)

Excessive lung release of neutrophil DNA traps may explain severe complications in Covid-19 patients
Researchers from the University of Liège (Belgium) has detected significant amounts of DNA traps in distinct compartments of the lungs of patients who died from Covid-19. These traps, called NETs, are released massively into the airways, the lung tissue and the blood vessels. Such excessive release could be a major contributor to severe disease complications leading to in-hospital death. These results are published this week in the Journal of Experimental Medicine. (2020-09-14)

New blood, new hope: Transfusions protect the brain from stroke damage
In a study led by Xuefang ''Sophie'' Ren, a research assistant professor in the Department of Neuroscience, a team of West Virginia University neuroscientists found that blood substitution therapy rescues the brains of mice from ischemic damage, a potential breakthrough in stroke therapy. (2020-08-25)

Promising discovery for patients with diabetic retinopathy
A study published in the journal Science has shed light on a cellular process that occurs in the retinas of people with diabetic retinopathy. This discovery could lead to the development of a treatment for this serious complication of diabetes. (2020-08-20)

LJI team gets first-ever look at a rare but vital stem cell in humans
Scientists at La Jolla Institute for Immunology (LJI) have tracked down the rare stem cells that generate neutrophils in human bone marrow. This research, published August 18, 2020, in Immunity, gives researchers a potential path for intervening in diseases where neutrophil development goes awry. (2020-08-18)

COVID-19 - The virus and the vasculature
In severe cases of COVID-19, the infection can lead to obstruction of the blood vessels in the lung, heart and kidneys. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have now shown that activated immune cells and blood platelets play a major role in these pathologies. (2020-08-07)

COVID-19: Immune system derails
Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition. Experts from Charité - Universitätsmedizin Berlin, the University of Bonn, the German Center for Neurodegenerative Diseases (DZNE), the Helmholtz Centre for Infection Research (HZI) and the German Center for Infection Research (DZIF), along with colleagues from a nationwide research network, present these findings in Cell. (2020-08-06)

Gut microbiome translates stress into sickle cell crises
A new study shows how chronic psychological stress leads to painful vessel-clogging episodes--the most common complication of sickle-cell disease (SCD) and a frequent cause of hospitalizations. The findings, made in mice, show that the gut microbiome plays a key role in triggering those episodes and reveals possible ways to prevent them. The research was conducted by scientists at Albert Einstein College of Medicine and published online today in Immunity. (2020-07-30)

Dual role discovered for molecule involved in autoimmune eye disease
The inflammatory molecule interleukin-17A (IL-17A) triggers immune cells that in turn reduce IL-17A's pro-inflammatory activity, according to a study by National Eye Institute (NEI) researchers. (2020-07-23)

Type 1 interferon deficiency: Biomarker of patients at risk of severe COVID
Which patients are more likely to develop a severe form of Covid-19? This is a key question that needs to be answered to improve the individual management and prognosis of patients. In a study published in Science on July 13, teams from AP-HP, Inserm, Université of Paris, Institut Pasteur and Institut Imagine describe a unique and unexpected immunological phenotype in severe and critical patients. (2020-07-17)

Penn researchers find three distinct immune responses for sicker COVID-19 patients
Researchers from the Penn Institute of Immunology discovered three distinct immune responses to the SARS-CoV2 infection that could help predict the trajectory of disease in severe COVID-19 patients and may ultimately inform how to best treat them. A second study from researchers at Penn uncovered new details about the innate, or initial, response to SARS-CoV2. (2020-07-15)

Analysis of immune responses in COVID-19 patients identifies defining features of severe disease
An analysis of immune responses in 42 COVID-19 patients, both infected and recovered, identified immune signatures that distinguish severe COVID-19 cases. Notably, the analysis features insights not only into adaptive immune cell responses, but also those of innate immune cells responding to the virus. (2020-07-15)

New evidence for how blood clots may form in very ill COVID-19 patients
Neutrophil Extracellular Traps (NETs) have been implicated in causing excessive clotting in cancer patients. In this study, researchers show that the amount of NETs correlates with the severity of disease in COVID-19 patients. They also found that lungs of some deceased COVID-19 patients were dotted with micro-clots of NET-producing cells and platelets. (2020-06-29)

Scientists propose strategy for site-selective chiral drug synthesis in living systems
Prof. QU Xiaogang from the Changchun Institute of Applied Chemistry (CIAC) of the Chinese Academy of Sciences and his colleagues recently presented a novel strategy using a neutrophil-directed ATH reaction to achieve site-selective chiral drug synthesis in living systems. (2020-06-26)

Hormone involved in obesity is a risk factor for sepsis
A group of scientists from Instituto Gulbenkian de Ciência (IGC), led by Luís Moita, discovered that a hormone that has been pointed out as a treatment for obesity reduces the resistance to infection caused by bacteria and is a risk factor for sepsis. (2020-06-22)

How rod-shaped particles might distract an out-of-control COVID immune response
A long-ignored white blood cell may be central to the immune system overreaction that is the most common cause of death for COVID-19 patients--and University of Michigan researchers found that rod-shaped particles can take them out of circulation. (2020-06-10)

Page 1 of 14 | 526 Results
   First   Previous   Next      Last   
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.