Current Occupational Therapy News and Events

Current Occupational Therapy News and Events, Occupational Therapy News Articles.
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Gut microbiota reveals whether drug therapies work in inflammatory bowel diseases
A study recently completed at the University of Helsinki indicates that the gut microbiota of patients suffering from inflammatory gastrointestinal disorders can be used to predict whether they will benefit from expensive therapies. The study also confirms the key role of therapies that have a beneficial effect on the gut microbiota in inflammatory bowel diseases. (2021-01-26)

Genome editing to treat human retinal degeneration
Gene editing therapies, including CRISPR-Cas systems, offer the potential to correct mutations causing inherited retinal degenerations, a leading cause of blindness. Technological advances in gene editing, continuing safety concerns, and strategies to overcome these challenges (2021-01-19)

Biodistribution of AAV gene transfer vectors in nonhuman primate
The biodistribution of adeno-associated virus (AAV) gene transfer vectors can be measured in nonhuman primates using a new method. The method quantifies whole-body and organ-specific AAV capsids from 1 to 72 hours after administration (2021-01-15)

Workaholism leads to mental and physical health problems
Workaholism or work addiction risk is a growing public health concern that can lead to many negative mental and physical health outcomes such as depression, anxiety or sleep disorder. Perception of work (job demands and job control) may become a major cause of employees' work addiction. The international group of researchers including the HSE University scientist explored the link between work addiction risk and health-related outcomes using the framework of Job Demand Control Model. (2021-01-13)

Treatment for chronic pain must address both physical and social pain
Physical pain and social pain may be more closely related than previously thought. Social pain, which typically results from interpersonal rejection or abuse, has been viewed as a non-medical response to external factors. However, recent research suggests that some physical and social stress responses may arise because of shared processing in the brain. (2021-01-12)

Ibrutinib with rituximab in previously untreated CLL: indication of added benefit over FCR
Ibrutinib with rituximab in previously untreated CLL: indication of added benefit over FCR. The new drug combination prolongs overall survival in patients in good general health. No study data are available for other patient groups. (2021-01-05)

Study published on the well-being of small business workers during COVID-19
This study, published in the Journal of Occupational and Environmental Medicine, examined whether safety and health climates were related to employee well-being during the COVID-19 pandemic in a sample of small businesses. (2020-12-21)

Oral hormone therapy shown to significantly alter metabolome of menopausal women
Groundbreaking research led by a team of scientists including a University of Massachusetts Amherst biostatistician shows that oral hormone therapy (HT) significantly alters the metabolome of postmenopausal women. This finding, which examined blood specimens from the landmark Women's Health Initiative (WHI) study, may help explain the disease risks and protective effects associated with different regimens of hormone therapy. (2020-12-16)

Gene therapy for placental insufficiency moves toward the clinic
A new study identified an adenovirus gene therapy vector carrying a VEGF isoform. It can improve uterine blood flow in placental insufficiency. (2020-12-15)

Robots could replace real therapy dogs
Robotic animals could be the 'pawfect' replacement for our real-life furry friends, a new study published today by the University of Portsmouth has found. (2020-12-10)

Phase 1 trial assesses whether fecal microbiota transplant impacts cancer patients resistant to immu
In one of the first in-human studies to investigate whether modifying the gut microbiome by a fecal microbiota transplant could make cancer immunotherapy more effective, researchers analyzing this in ten cancer patients with refractory melanoma suggest the treatment can improve patient outcomes. (2020-12-10)

AAV capsid-promoter interactions in the non-human primate brain
The phenomenon of AAV capsid-promoter interaction recently seen in the rat central nervous system has now been shown to occur in the non-human primate brain. This interaction can directly determine cell-specific transgene expression (2020-12-10)

Omitting radiation therapy after breast-conserving surgery may not impact 10-year survival rates for older patients with HR-positive breast cancer
Older patients with hormone receptor-positive breast cancer who did not receive radiation therapy after breast-conserving surgery had higher rates of local recurrence but similar 10-year survival rates when compared to patients who received postoperative radiation therapy, according to updated 10-year data from the PRIME II study, presented at the 2020 San Antonio Breast Cancer Symposium. (2020-12-09)

Single-eye gene therapy improves vision in both eyes of patients with inherited eye disorder
A gene therapy for an inherited eye disorder can ameliorate vision loss in both eyes despite only being injected into one, according to a phase 3 clinical trial involving 37 patients. (2020-12-09)

Recommendations for coping with working and learning remotely and returning to the workplace
WORK: A Journal of Prevention, Assessment & Rehabilitation, published by IOS Press, is committed to helping organizations manage the challenges they face during the COVID-19 pandemic by publishing robust, evidence-based research and commentary. All articles featured here and in the WORK COVID-19 Collection are freely available. (2020-12-09)

Human systems management critical for businesses during COVID-19
Amsterdam, NL, December 8, 2020 - The COVID-19 pandemic has disrupted all types of organizations, leading human resources managers to reconsider their roles to support the implementation of social distancing practices, safety measures, and new ways of working. A special issue of Human Systems Management looks at the behavioral challenges posed by new ways of working and presents new models and tools to help organizations manage the transition. (2020-12-08)

CAR T cell therapy effective as first-line treatment for high-risk large B-cell lymphoma
A study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy, is a safe and effective first-line therapy for patients with high-risk large B-cell lymphoma (LBCL), a group with an urgent need for new and effective treatments. (2020-12-06)

New CCNY-developed resource measures severity of work-related depression
First came their pioneering research a few years ago linking burnout and depression. Now CCNY psychologist Irvin Schonfeld and his University of Neuchâtel collaborator Renzo Bianchi present the Occupational Depression Inventory [ODI], a measure designed to quantify the severity of work-attributed depressive symptoms and establish provisional diagnoses of job-ascribed depression. (2020-12-04)

Secukinumab in children with plaque psoriasis: Study unsuitable for benefit assessment
Secukinumab in children with plaque psoriasis: study unsuitable for benefit assessment The comparator group was not treated appropriately. Firstly, therapy in this group remained unchanged despite non-response, and secondly, it was continued for longer than approved. (2020-12-04)

Anorexia patients tolerate rapid weight gain with meal-based behavioral support
A new study by Johns Hopkins Medicine researchers of adults hospitalized for the eating disorder anorexia nervosa has strengthened the case for promoting rapid weight gain as part of overall efforts. (2020-12-03)

Role of birth order on career choice might have been overestimated in previous research
In a new study that could turn what we know about birth order upside down, a University of Houston researcher has found that the role of birth order on career types, occupational creativity and status attainment might have been overestimated in previous research. (2020-12-03)

Study finds over 64% of people reported new health issues during 'work from home'
In a new study, researchers have found that working from home has negatively impacted our physical health and mental health, increased work expectations and distractions, reduced our communications with co-workers and ultimately lessened our productivity. The study finds that time spent at the workstation increased by approximately 1.5 hours. It also illustrates the differential impact of working from home for women, parents, and those with higher income (2020-12-03)

People returning home from skilled nursing facilities need tailored instructions
Transitions from a skilled nursing facility to home are burdensome to already vulnerable individuals and are points in time where errors and gaps in care are more likely. COVID-19 has exacerbated transitional challenges, which can affect quality of life and cause the patient to lose progress made during their stay at a care facility. (2020-12-02)

Unmet job expectations linked to a rise in suicide, deaths of despair
The study, published in JAMA Network Open, is the first to link the rise in suicide and drug-poisoning deaths among men without a college degree to declines in working-class jobs. (2020-12-02)

In-stent thrombosis after antiplatelet therapy conversion while awaiting coronary bypass
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0589, Nathan Burke, Tawanna Charlton, Hussam Hawamdeh, and Ki Park from the University of Florida College of Medicine, Gainesville, Florida, USA consider a case study of in-stent thrombosis after antiplatelet therapy conversion while awaiting coronary bypass. (2020-11-19)

NIH gene therapy startup to increase AAV gene therapy efficiency
Maximizing the efficiency of the adeno-associated virus (AAV) platform for gene therapy is the aim of a new pilot project of the National Institutes of Health (NIH). (2020-11-17)

Risk of AAV mobilization in gene therapy
New data highlight safety concerns for the replication of recombinant adeno-associated viral (rAAV) vectors commonly used in gene therapy. These findings, which emphasize the need for mobilization resistant AAV vectors (2020-11-13)

Is proton therapy the silver bullet for children with brain cancer?
How safe is proton therapy for children with brain cancer compared to the conventional x-ray radiation delivered post-surgery? (2020-11-11)

3D printed stents that treat inflammation
POSTECH Professor Dong-Woo Cho's research team develops bioink-loaded esophageal stents for treating radiation esophagitis. (2020-11-10)

Induced liver regeneration enhances CRISPR/Cas9-mediated gene repair
Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver. This dietary induction of hepatocyte regeneration may be a viable clinical strategy to enhance gene repair in the liver. (2020-11-10)

Brain effects of repetitive low-level occupational blast exposure
Military and law enforcement personnel with extensive occupational blast exposure had statistically significant differences in brain imaging measures compared to nonexposed control personnel (2020-11-03)

ASTRO: Proton therapy for lung cancer may help reduce risk of heart diseases
Treating lung cancer patients with proton therapy may help reduce the risk of radiation-induced heart diseases. (2020-10-23)

Antiretroviral therapy can't completely stop accelerated cell aging seen in HIV
Untreated HIV infection is linked with epigenetic changes that suggest rapid aging. A new study by UCLA researchers shows that antiretroviral therapy given over two years was unable to completely restore age-appropriate epigenetic patterns, leaving patients more susceptible to aging-related illnesses. (2020-10-22)

Serum creatinine-to- cystatin C ratio predicts mortality
In patients initiating continuous renal replacement therapy for acute kidney injury, higher serum creatinine-to-cystatin C ratios were associated with lower mortality. (2020-10-21)

Therapy plus medication better than medication alone in bipolar disorder
A review of 39 randomized clinical trials by scientists from UCLA and their colleagues from other institutions has found that combining the use medication with psychoeducational therapy is more effective at preventing a recurrence of illness in people with bipolar disorder than medication alone. (2020-10-14)

Treating cystic fibrosis with mRNA therapy or CRISPR
The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible (2020-10-08)

Fostamatinib in chronic immune thrombocytopenia: No comparison -- added benefit not proven
Fostamatinib in chronic immune thrombocytopenia: no comparison -- added benefit not proven The manufacturer conducted no direct or indirect comparison of its drug with an appropriate comparator therapy (eltrombopag or romiplostim). (2020-10-06)

Scientists propose immune cocktail therapy to boost cancer-immunity cycle in multiple aspects
A research team led by Prof. TIAN Huayu from the Changchun Institute of Applied Chemistry (CIAC) of the Chinese Academy of Sciences proposed an innovative immune cocktail therapy that combined ICT along with other therapeutic approaches. The cocktail therapy achieved multiple boosting of the cancer-immunity cycle by utilizing a nano-delivery system. (2020-09-30)

"There's no place like home" for rehab after stroke
Stroke patients who get professional rehabilitation training in their homes through live video consultations may recover their motor skills better than those who do their rehab in person with a therapist at an outpatient rehabilitation facility, according to a study published in the September 30, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology. Remote rehabilitation may also promote greater brain connectivity, the study said. (2020-09-30)

Putting virtual rehab for stroke patients to the test
Researchers have created a new gaming platform which uses low cost videogame technology to improve the lives of stroke patients suffering from complex neurological syndromes caused by their stroke. It is hoped that the new technology, which can be used in patients' own homes, could prove particularly beneficial for rehabilitation during periods of lockdown, social distancing and shielding - caused by the Covid-19 pandemic. (2020-09-24)

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