Current Oncology News and Events

Current Oncology News and Events, Oncology News Articles.
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Surface testing for SARS-CoV2 in hematology/oncology settings reveals negligible detection
Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, evaluated the frequency of SARS-CoV-2, the virus that causes COVID-19, on various environmental surfaces in outpatient and inpatient hematology/oncology settings located within Rutgers Cancer Institute and Robert Wood Johnson University Hospital, an RWJBarnabas Health facility. The study revealed extremely low detection of SARS-CoV-2 on environmental surfaces across multiple outpatient and inpatient oncology areas, including an active COVID-19 floor. (2021-02-18)

Unexpected findings on weight loss and breast cancer from international study in JNCCN
New research in the February 2021 issue of JNCCN--Journal of the National Comprehensive Cancer Network examined body mass index (BMI) data for people with HER2-positive early breast cancer, and found a 5% weight loss in patients over two years in was associated with worse outcomes. Weight gain over the same time period did not affect survival rates. (2021-02-16)

Model helps predict which patients will benefit most from PSMA PET scan
A new study led by researchers at the UCLA Jonsson Comprehensive Cancer Center helps identify which patients with prostate cancer will benefit most from the use of prostate-specific membrane antigen PET imaging, PSMA PET, a novel imaging technique that recently was approved by the U.S. Food and Drug Administration. (2021-02-16)

Liquid biopsy for colorectal cancer could guide therapy for tumors
A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer that has just begun to spread beyond the original tumor. Such a biopsy can detect lingering disease and could serve as a guide for deciding whether a patient should undergo further treatments due to some tumor cells evading an initial attempt to eradicate the cancer. (2021-02-12)

Patients with lung cancer reduce smoking rate after enrollment in phase III clinical trial
The first comprehensive, prospective study of smoking habits in patients with non-small cell lung cancer (NSCLC) who were enrolled in a phase III early-stage trial revealed that there was a high rate of smoking reduction and cessation following study entry, according to research published today in the Journal of Thoracic Oncology. (2021-02-01)

Reduced-dose RT with Cisplatin improves outcomes for HPV-associated oropharyngeal carcinoma
A combination of reduced-dose radiotherapy using intensity-modulated radiotherapy (IMRT) combined with concurrent cisplatin met the threshold for disease control and quality of life compared to the standard of care for good-risk patients with HPV-associated oropharyngeal squamous cell carcinoma on the NRG Oncology clinical trial NRG-HN002. (2021-01-29)

Study finds shorter radiation regimen safe, effective for men with advanced prostate cancer
UCLA researchers found shortening a traditional 45-day course of radiation to a five-day course delivered in larger doses is safe and as effective as conventional radiation for men with high-risk forms of prostate cancer. (2021-01-25)

Detailed tumour profiling
As part of a clinical study involving patients from the University Hospitals in Zurich and Basel, researchers are conducting a thorough and highly precise investigation into the molecular and functional properties of tumours. Their goal is to help physicians to better determine which treatment will best match every patient's cancer and thus be most effective. (2021-01-21)

Routine thoracic surgery safe during COVID-19 pandemic
A study in the Journal of Thoracic Oncology (JTO) comparing surgeries performed at one Chinese hospital in 2019 with a similar date range during the COVID-19 pandemic found that routine thoracic surgery and invasive examinations were performed safely. The JTO is the official journal of the International Association for the Study of Lung Cancer. (2021-01-19)

How effective are educational support programs for children with cancer?
As children undergo treatment for cancer, they may miss school and risk falling behind in their education. An analysis published in Pyscho-Oncology has examined the educational support programs provided to children with cancer. (2021-01-06)

FDA Oncology Center of Excellence during COVID-19
This Viewpoint discusses initiatives of the U.S. Food and Drug Administration's Oncology Center of Excellence to address COVID-19-related challenges faced by patients with cancer and the health care professionals who provide cancer treatment. (2020-12-23)

Palliative care improves quality of life for patients with advanced blood cancer
A first-of-its-kind intervention integrating palliative care early in the course of cancer therapy for patients with advanced acute myeloid leukemia (AML), a highly aggressive cancer of the blood and bone marrow, resulted in substantial improvements in patients' quality of life, mood and end-of-life care, a team of investigators has found. (2020-12-17)

Fans may relieve breathlessness associated with advanced cancers
Blowing air from a fan into the face of patients with advanced cancer experiencing breathlessness, and other nonpharmacologic interventions, may offer symptom relief, according to new research directed by Johns Hopkins Kimmel Cancer Center investigators. (2020-12-10)

New guidelines for treating the complications of brain tumours
Experts from the leading oncology societies ESMO (European Society for Medical Oncology) and EANO (European Association of Neuro-Oncology) hav now compiled international guidelines and standards for the treatment of complications of brain tumours (2020-12-09)

Disrupting the cellular process that promotes pancreatic cancer's deadly growth
Researchers say they've identified a way to disrupt a process that promotes the growth of pancreatic cancers -- one of the most difficult and deadly cancers to treat. (2020-12-08)

First report card on biosimilars in oncology
In a Policy Review in The Lancet Oncology, Y. Tony Yang, a professor at the George Washington University School of Nursing and Milken Institute School of Public Health, along with his co-authors, identify factors preventing the effective launch of oncology biosimilars in the United States, including the struggle to garner market share and fighting patent litigation lawsuits across the country. (2020-12-01)

Frozen eggs and ovarian tissue helped women conceive children after breast cancer
Women with breast cancer whose eggs or ovarian tissue were frozen had more children after their diagnosis than women who did not undergo fertility preservation using those methods before start of cancer treatment. That is according to a study by researchers at Karolinska Institutet in Sweden that is published in the journal JAMA Oncology. According to the researchers, the result highlights the importance of reproductive counseling and fertility preservation for women who are diagnosed with cancer at a young age. (2020-11-19)

Sexual health often overlooked in cancer survivorship care, especially for female patients
A new study points to a need for oncologists to ask their patients about sexual health after chemotherapy, radiation and other cancer treatments. In a survey of nearly 400 cancer survivors, 87% said they experienced sexual side effects, but most also said their oncologist had not formally asked about them. Female patients were especially unlikely to be asked about sexual dysfunction. Findings will be presented at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-30)

Study of COVID-19 levels in oncology staff suggests need for more extensive testing
A study of oncology staff carried out immediately after the spring peak of the COVID-19 pandemic in the UK indicates that many had been infected with the coronavirus as they tested positive for COVID-19 antibodies. This included staff who did not show any symptoms. (2020-10-29)

Study reveals impact of COVID-19 on oncology staff and their work
A study presented at the NCRI Virtual Showcase reports the results of a survey of oncology staff on their management of patients, their wellbeing and whether they felt valued during the first wave of the COVID-19 pandemic. (2020-10-29)

Validation of ERCC1/2 signature as radiosensitivity biomarker for tumor & normal tissues in NSCLC
A genetic analysis of non-small cell lung cancer (NSCLC) patients on the phase III NRG Oncology RTOG 0617 clinical trial assessing radiation dose discovered that high dose radiation therapy is associated with shorter survival times among patients with a radiation-sensitive genotype in DNA repair pathway. These findings were presented at the virtual edition of the American Society for Radiation Oncology's (ASTRO) Annual Meeting in October 2020. (2020-10-28)

Outcomes of salvage low dose RT brachytherapy after EBRT for prostate cancer
Researchers involved in the phase II NRG Oncology RTOG 0526 trial studying low dose rate (LDR) prostate brachytherapy (BT) following local recurrence (LR) after external beam radiotherapy (EBRT) for patients with low-to-intermediate risk prostate cancer reported late Grade 3 gastrointestinal and genitourinary adverse events (AEs) occurring in 14% of trial participants. (2020-10-28)

MFS Is a strong surrogate endpoint for OS for men receiving salvage RT for recurrent prostate cancer
An analysis of the phase III NRG Oncology clinical trial RTOG 9601 on men receiving salvage radiotherapy (SRT) following prostatectomy for recurrent prostate cancer indicated that, while biochemical failure (BF) was not a strong surrogate endpoint to determine overall survival (OS), metastasis-free survival (MFS) was in this patient population. (2020-10-26)

Group trial bolsters case for stereotactic radiation for tumors that travel to the lungs
A new study, conducted across 13 medical centers in Australia and New Zealand, strengthens the case for radiation therapy as a treatment for cancer that has begun to spread throughout the body. Findings of the SAFRON II trial (NCT01965223) will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-26)

Radiosurgery reduces cognitive decline without compromising survival for pts with 4+ brain mets
Results of a new randomized phase III trial suggest that stereotactic radiosurgery (SRS) should replace whole brain radiation therapy (WBRT) as the standard of care for patients with four or more brain metastases. Results from the clinical trial (NCT01592968) will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-26)

Effectiveness of gemcitabine & daily RT for bladder preservation in muscle-invasive bladder cancer
Bladder preservation with trimodality therapy can be a safe and effective alternative to cystectomy for selected patients with muscle-invasive bladder cancer. The phase II NRG Oncology NRG-RTOG 0712 trial evaluated two regimens. One was the prior RTOG standard using 5-flourouracil and cisplatin with twice daily radiation (FCT), and the other a regimen of gemcitabine and daily radiation (GD) which had demonstrated efficacy in single institution clinical trials. (2020-10-26)

Photon IMRT treatment group displays no significant survival difference between arms
A preliminary analysis of photon therapy treatment group 1 from the phase II NRG Oncology clinical trial NRG-BN001 indicates that there is no statistically significant overall survival (OS) or toxicity differences between dose-intensification radiation therapy (DI-RT) using intensity-modulated radiation therapy (IMRT) and standard-dose radiation therapy (SD-RT) with temozolomide treatments for patients with newly diagnosed glioblastoma (GBM). (2020-10-26)

ASTRO: Proton therapy for lung cancer may help reduce risk of heart diseases
Treating lung cancer patients with proton therapy may help reduce the risk of radiation-induced heart diseases. (2020-10-23)

ASTRO issues clinical guideline on radiation therapy for rectal cancer
A new clinical guideline from the American Society for Radiation Oncology (ASTRO) provides guidance for physicians who use radiation therapy to treat patients with locally advanced rectal cancer. Recommendations outline indications and best practices for pelvic radiation treatments, as well as the integration of radiation with chemotherapy and surgery for stage II-III disease. The guideline, which replaces ASTRO's 2016 guidance for rectal cancer, is published in Practical Radiation Oncology. (2020-10-21)

Immunotherapy combo halts rare, stage 4 sarcoma in teen
The patient, whose tumor responded within two weeks after receiving the combination, resumed normal activity and was in a complete remission at the time of the report. (2020-10-16)

Radiation oncology research and clinical trials to be featured at ASTRO's Annual Meeting
The American Society for Radiation Oncology (ASTRO) announced today the press program for its 2020 Annual Meeting, which will feature studies on cancer treatment advances and discussions of topical issues including COVID-19. Researchers will present their findings via live webcasts on October 26 and 27. Register for press access at www.astro.org/annnualmeetingpress. (2020-10-14)

Enhanced reimbursement to oncology clinics increases prescriptions of evidence-based drugs
A pay-for performance program that offers enhanced reimbursement to oncology practices for prescribing high-quality, evidence-based cancer drugs increased use of these drugs without significantly changing total spending on care, Penn Medicine researchers report in a new study published online in the Journal of Clinical Oncology. (2020-10-07)

The number and clonality of TCRs are associated with the prognosis of colorectal cancer
This study has used a new technique called 'T-cell receptor (TCR) immuno-sequencing', which allows us to obtain both the number of T lymphocytes that infiltrate the tumor and their clonality index. (2020-10-06)

Colorectal cancer treatment: the winning combinations
Chemotherapy has distressing side effects for patients and increases the risk of developing resistance to the treatment. In an attempt to solve these problems, scientists from the University of Geneva have developed a technique for quickly identifying from a large number of existing drugs the optimal synergistic combination and dose of products that can kill the tumour cells without affecting healthy cells. This study further paves the way for personalised, effective and safe cancer treatment. (2020-10-06)

New tools improve care for cancers that spread to the brain
The UVA team says its findings will help doctors and patients make better-informed treatment decisions, enhance the care of brain metastases, and enable hospitals to improve the coordination and effectiveness of their interdisciplinary treatment programs. (2020-10-05)

Molecules responsible for radio-resistant glioblastoma identified
Scientists have identified key molecules that mediate radioresistance in glioblastoma multiforme; these molecules are a potential target for the treatment of this brain cancer. (2020-09-30)

Breast cancer medication risk
New research led by Flinders University has found a link between beta-blockers and survival outcomes in some breast cancer patients. Beta-blockers, commonly used to manage cardiovascular disease, were negatively associated with survival outcomes in patients with HER2 (Human Epidermal Growth Factor Receptor 2) positive advanced breast cancer, according to a new paper in the Frontiers In Oncology. (2020-09-29)

Three common medications lower risk and mortality for lung cancer
Combined use of aspirin, statins, and metformin is associated with decreased lung cancer incidence and mortality, according to a study published in the Journal of Thoracic Oncology (JTO). The JTO is the official journal of the International Association for the Study of Lung Cancer. (2020-09-17)

COVID-19 pandemic halts cancer care and damages oncologists' wellbeing
Delays and cancellation of cancer treatments and other safety measures undertaken to minimise the risk of exposure to the coronavirus (COVID-19) have generated a huge backlog in oncology care and research. The threat of delayed diagnoses looms while oncology professionals face burnout, according to new studies discussed at the ESMO Virtual Congress 2020. (2020-09-14)

New drug could improve life expectancy and quality for pancreatic cancer patients
First-in-class drug starves certain tumor types of the resources they need to grow and spread to other parts of the body. (2020-09-09)

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