Current Opioids News and Events

Current Opioids News and Events, Opioids News Articles.
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Seasonal variation in daylight influences brain function
A Finnish research group has studied how seasons influence the function of the brain. Researchers at the Turku PET Centre showed that the length of daylight affects the opioid receptors, which in turn regulates the mood we experience. (2021-02-23)

West Virginia's enduring, intertwined epidemics: Opioids and HIV
In a paper for The Lancet, West Virginia University Drs. Sally Hodder and Judith Feinberg state that the opioid and HIV epidemics are intertwined in West Virginia, and therefore should be treated together. (2021-02-22)

Three longtime antibiotics could offer alternative to addictive opioid pain relievers
Three decades-old antibiotics administered together can block a type of pain triggered by nerve damage in an animal model, UT Southwestern researchers report. The finding, published online today in PNAS, could offer an alternative to opioid-based painkillers, addictive prescription medications that are responsible for an epidemic of abuse in the US. (2021-02-22)

High patient uptake for text message system monitoring opioid use in real-time
Among the orthopaedic surgery patients in a study using text messaging to monitor opioid use, 61 percent of their tablets were found to be left over (2021-02-17)

IU study finds unintended consequences of state, opioid policies
Study reveals the unintended and negative consequences of policies designed to reduce the supply of opioids in the population for overdose. (2021-02-17)

Low-value health care drops only marginally despite effort to curb practices
An estimated 10% to 20% of health care spending consists of low-value care -- patient services that offer no net clinical benefit in specific scenarios. A new study finds that spending on low-value health care among fee-for-service Medicare recipients dropped only marginally from 2014 to 2018, despite both a national campaign to better educate clinicians and increasing use of payment revisions that discourage wasteful care. (2021-02-16)

New hope for treating chronic pain without opioids
According to some estimates, chronic pain affects up to 40% of Americans, and treating it frustrates both clinicians and patients--a frustration that's often compounded by a hesitation to prescribe opioids for pain. (2021-02-15)

Mexico's poor have little luck obtaining opioids intended for palliative care
Despite a Mexican government initiative to improve access to prescription opioids among palliative care patients, the country has seen only a marginal increase in dispensing levels, and inequities in dispensing have left many of the nation's poorest residents without comfort in their final days. (2021-02-11)

Lipid epoxides target pain, inflammatory pathways in neurons
When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, researchers report. These modified compounds, called epo-NA5HT and epo-NADA, have much more powerful effects than the molecules from which they are derived, which also regulate pain and inflammation. (2021-02-10)

Experimental vaccine blunts the deadliest of synthetic opioids
As the opioid epidemic raged on with an even greater force during COVID-19, the Scripps Research laboratory of chemist Kim Janda, PhD, has been working on new therapeutic interventions that may be able to prevent the bulk of deaths from opioid overdose. Janda and his team have developed experimental vaccines that have shown in rodents to blunt the deadly effects of fentanyl as well as its even more fatal cousin, carfentanil. (2021-02-04)

Model predicts likelihood of persistent high-dose opioid use after knee surgery
A new study published in Arthritis Care & Research has identified 10 readily available clinical factors that may predict which patients will persistently use high doses of opioids in the year following knee replacement surgery. (2021-02-03)

Opioid prescriptions remained elevated two years after critical care
Nearly 11 percent of people admitted to an ICU in Sweden between 2010 and 2018 received opioid prescriptions on a regular basis for at least six months and up to two years after discharge. That is according to a study by researchers at Karolinska Institutet published in Critical Care Medicine. The findings suggest some may become chronic opioid users despite a lack of evidence of the drugs' long-term effectiveness and risks linked to increased mortality. (2021-02-02)

Nutrition, companionship reduce pain in mice with sickle cell disease, UCI-led study finds
Researchers from the University of California, Irvine and the University of Minnesota have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin. They also discovered that duloxetine, an antidepressant that boosts serotonin levels, could be an alternative to opioids in treating chronic pain. (2021-02-01)

When rhinos fly: Upside down the right way for transport
When it comes to saving endangered species of a certain size, conservationists often have to think outside the box. (2021-02-01)

Enhanced recovery efforts for cesarean delivery reduce need for opioids by 80%
In a retrospective analysis of cesarean deliveries from 2015 through 2020, doctors from the Colorado Fetal Care Center at Children's Hospital Colorado found that using a wound infusion pump in combination with enhanced recovery efforts like removing urinary catheters earlier and walking around the same day of surgery can reduce opioid use by more than 80%. Also notable, researchers found a third of patients never took a single narcotic pain pill after cesarean delivery. (2021-01-28)

Counties with more cannabis dispensaries show reduced opioid deaths
This is the first study to examine the association between active cannabis dispensary operations -- both medical and recreational -- and opioid-related mortality rates at the county level, suggesting that providing alternative pain management could improve public health outcomes, researchers said. (2021-01-28)

Pain patients who take opioids can't get in the door at over half of primary care clinics
People who take opioid medications for chronic pain may have a hard time finding a new primary care clinic that will take them as a patient if they need one, according to a new 'secret shopper' study of hundreds of clinics across the country. Stigma against long-term users of prescription opioids, likely related to the prospect of taking on a patient who might have an opioid use disorder or addiction, appears to play a role. (2021-01-27)

Controlling pain after surgery doesn't have to mean opioids, study shows
As surgeons balance the need to control their patients' post-surgery pain with the risk that a routine operation could become the gateway to long-term opioid use or addiction, a new study shows the power of an approach that takes a middle way. (2021-01-27)

Legal cannabis stores linked to fewer opioid deaths in the United States
Access to legal cannabis stores is associated with a reduction in opioid related deaths in the United States, particularly those linked to synthetic opioids such as fentanyl, finds a study published by The BMJ today. (2021-01-27)

Modified pain management strategy reduces opioid exposure to trauma patients, study shows
A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at UTHealth. (2021-01-21)

New study examines medical practice patterns over time
Variations in medical practice can have serious consequences for the quality, equity and cost of one's health care; however, it's unclear whether these disparities can be attributed to individual differences, from one doctor to another or to changes in your doctor's individual practice over time, perhaps in response to shifts in clinical guidelines or advancements in diagnostic technologists. (2021-01-12)

The link between opioid medication and pancreatic cancer
Using Center for Disease Control's national population health and cancer statistics datasets, Rush University Medical Center researchers determined that a state's opioid death rate significantly predicted the trend in the incidence of pancreatic cancer years later. This is the first study showing opioid use may be a risk factor contributing to the increasing incidence of pancreatic cancer (2021-01-06)

Perspective: Why opioids cannot fix chronic pain
New epidemiological and neuroscientific evidence suggests that the relationship between chronic pain and emotional distress is bidirectional. Pain experts at University of Washington School of Medicine explain the relation in Annals of Family Medicine. (2020-12-22)

Childhood intervention can prevent 'deaths of despair'
Mortality rates among young adults are rising in the US due in part to 'deaths of despair' -- preventable deaths from suicide, drug overdoses and alcohol-related liver disease. An intensive childhood intervention program called Fast Track could help reduce these deaths by reducing risky behaviors in adolescence and young adulthood, finds new research from Duke University and the Conduct Problems Prevention Research Group. (2020-12-17)

Mindfulness meditation may decrease impact of migraine
In a recent clinical trial from Wake Forest Baptist Health, researchers showed that mindfulness-based stress reduction (MBSR) may provide benefit to people with migraine. (2020-12-14)

Fewer than 2 percent of OB-GYN doctors can prescribe life-saving opioid treatment
Examining country-wide data, the researchers hoped to gauge how many obstetrician-gynecologists have their waiver to prescribe buprenorphine (2020-12-11)

Fans may relieve breathlessness associated with advanced cancers
Blowing air from a fan into the face of patients with advanced cancer experiencing breathlessness, and other nonpharmacologic interventions, may offer symptom relief, according to new research directed by Johns Hopkins Kimmel Cancer Center investigators. (2020-12-10)

Mastectomy and reconstructive surgery may lead to patients becoming persistent drug users
Women who receive mastectomy and reconstructive surgery as part of breast cancer treatment may face the risk of developing persistent use of opioids and sedative-hypnotic drugs, according to data presented at the 2020 San Antonio Breast Cancer Symposium. (2020-12-09)

After CDC guidance, little change in opioid prescriptions to those at risk of misuse
Research from Saint Louis University finds that among patients at risk for opioid misuse, the odds of receiving a Schedule II opioid (those with high abuse potential) for non-cancer pain were similar to those not at risk, despite new prescribing guidelines from the Centers for Disease Control (CDC). (2020-12-02)

Study: Opioid overdose deaths involving other substances more common in youth
Results of a new study show that opioid overdose deaths involving more than one substance (polysubstances) are more common than opioid-only overdose deaths among youth. Led by researchers at Boston Medical Center's Grayken Center for Addiction, the data shows that cocaine and other stimulants like crystal methamphetamine are the substances most commonly involved in opioid overdose deaths in young people between the ages of 13 and 25. (2020-11-23)

Limited access to buprenorphine restricts resident physicians treating opioid abusers
A University of South Florida Health-led survey of resident physicians in Florida indicates they are interested in treating opioid addiction but face barriers to offering patients treatment using buprenorphine, an FDA-approved medication shown to successfully decrease opioid use, overdose events, and deaths associated with opioids. Many states have reported increased deaths from opioids since the COVID-19 epidemic began, underscoring the need to remove barriers to care. (2020-11-20)

UTSA researcher examines drug overdose mortality in the Hispanic community
UTSA researcher Manuel Cano, assistant professor in the Department of Social Work at UTSA is shedding light to understand the topic of drug overdose deaths in the Hispanic community. In the article ''Drug Overdose Deaths Among US Hispanics: Trends (2000-2017) and Recent Patterns'' published in ''Substance Use & Misuse'' Cano used national death certificate data (data recording all deaths of U.S. residents) to examine drug overdose mortality in different Hispanic subgroups, based on heritage, place of birth and gender. (2020-11-18)

Model helps predict which infants may develop NAS
A new Vanderbilt-designed prediction model may make it easier to determine which infants will go on to develop neonatal abstinence syndrome (NAS), a drug withdrawal syndrome in newborns that occurs after exposure to opioids during pregnancy. (2020-11-12)

Pediatric surgeon establishes first-ever guidelines for pediatric opioid prescribing
In addition to adults, opioid addiction and misuse affects the pediatric population. Pediatric surgeon forms group of health care providers and advocates to establish first ever pediatric opioid prescribing guidelines. (2020-11-11)

Taking a scalpel to opioid painkiller risks: New studies show progress and opportunity
Several new studies add to the understanding of risks from surgical opioids, and show what happens when surgical teams work together to reduce the emphasis on, and supply of, opioid painkillers while still seeking to ease surgery patients' pain. (2020-11-10)

Researchers urge healthcare providers to routinely ask patients about cannabis use
Healthcare providers should talk to patients about their cannabis use the same way they talk about other habits like smoking and drinking: routinely and without judgment. Marian Wilson, lead author on a new paper about shared decision-making in talking about cannabis use, says some studies have suggested cannabis use is beneficial to patients with chronic pain who are also using opioids, which is why many in that patient population are using cannabis or considering it. (2020-11-05)

Opioid use disorder? Electronic health records help pinpoint probable patients
A new study suggests that patients with opioid use disorder may be identified using information available in electronic health records, even when diagnostic codes do not reflect this diagnosis. The study demonstrates the utility of proxies coding for DSM-5 criteria from medical records to generate a quantitative DSM-5 score that is associated with opioid use disorder severity. The study methods are unique in deriving a severity score that aims to mirror severity scores from more traditional interview-based diagnostic procedures. (2020-10-21)

From pills to powder: 1 in 3 high school seniors who misused prescription opioids later used heroin
Nearly one-third of students who reported misusing prescription opioids as high school seniors between 1997 and 2000, but did not have a history of medical use, later used heroin by age 35, according to a University of Michigan study. (2020-10-20)

Study finds room for improvement when hospital patients transition to hospice care
Terminally ill patients referred to hospice care from a hospital setting tend to be on hospice for shorter periods than those who enter hospice while living at home or in a residential care facility. (2020-10-16)

Opioid prescriptions are rising in the U.K, with 14% of patients becoming long-term users
In the U.K., new prescriptions for multiple opioids have risen steadily in recent years, leading to concerning rates of long-term use, especially in older, socially deprived patients. Dr Meghna Jani at the University of Manchester and colleagues report these findings in a new study published October 15 in PLOS Medicine. (2020-10-15)

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