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Current Opioids News and Events, Opioids News Articles.
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Managing pain after sports medicine surgery
A Henry Ford Hospital study published in the Journal of Arthroscopic and Related Surgery has found that patients who underwent knee surgery and other types of sports medicine procedures could manage their pain without opioids or a minimal dosage. (2020-06-17)

Brain research sheds light on the molecular mechanisms of depression
A new study conducted in Turku, Finland, reveals how symptoms indicating depression and anxiety are linked to brain function changes already in healthy individuals. (2020-06-16)

Study shows opioid, sedative and antidepressant use pre-surgery leads to worse outcomes
A study led by University of Kentucky Markey Cancer Center researchers showed that patients who already used opioids, sedatives or antidepressants prior to colorectal surgery experience significantly more complications post-surgery. (2020-06-08)

Opioid prescriptions after childbirth linked to increased risk of overdose, persistent use
Women who are prescribed opioids after childbirth have an increased risk of persistent opioid use or other serious opioid-related events, including overdose, in their first year postpartum, according to a new study by Vanderbilt University Medical Center researchers. This is true regardless of whether the woman had a vaginal delivery or a cesarean section. (2020-06-08)

Largest study of its kind of women in labor finds nitrous oxide safe, side effects rare
Researchers at the University of Colorado College of Nursing and the School of Medicine Department of Anesthesiology at the Anschutz Medical Campus found that the use of nitrous oxide (N2O) as a pain relief option for individuals in labor is safe for newborn children and laboring individual, and converting to a different form of pain relief such as an epidural or opioid is influenced by a woman's prior birth history and other factors. (2020-05-29)

Age, sex and smoking influence opioid receptor function in the brain
Opioids regulate the feelings of pleasure and pain in the brain. A study by the national Turku PET Centre in Finland shows that age, sex and smoking influence μ-opioid receptor density in the brain. The results of the study help to better understand the differences between individuals when it comes to neuropsychiatric disorders. (2020-05-28)

Nordic countries struggle with a severe drug overdose problem
Despite the fact that the Nordic countries are often seen as ideal in practically every global ranking of quality of life and social equality, the number of drug-related deaths in these countries are among the highest in Europe. (2020-05-27)

Impact of a health system's three-pronged strategy to address the opioid epidemic
In the past two decades more than 700,000 people have died from a drug overdose in the United States. In 2017, more than 68% of the drug overdose deaths involved an opioid. To help stem this epidemic, Highmark Inc. developed, implemented and evaluated a series of quality management-focused opioid interventions utilizing a three-pronged public health approach. (2020-05-27)

Majority of cannabis use in Vancouver's Downtown Eastside for therapeutic purposes
Most people at high risk of overdose in Vancouver's Downtown Eastside who use cannabis do so for pain relief and other therapeutic reasons -- and they may be at lower risk of overdosing on opioids as a result, suggests new research published in the peer-reviewed journal PLOS ONE. (2020-05-25)

Pain doesn't take a holiday: Dental opioids study points to need for better prescribing
As dentists and their teams across America get back to their regular schedules after a sharp COVID-19-related reduction, a new study shows a key opportunity to reduce the use of opioid painkillers by patients. The analysis of four years' worth of data from two million patients show that those who had dental procedures on a Friday or day before a holiday were much more likely to fill a prescription for an opioid than other patients. (2020-05-22)

Specially designed footwear reduces pain of knee osteoarthritis
Wearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee osteoarthritis. (2020-05-12)

Comparing opioid-related deaths among cancer survivors, general population
Death certificate data were used to compare the rate of opioid-related deaths in the US among cancer survivors with that of the general population from 2006 through 2016. Whether opioid-associated deaths in cancer survivors, who are often prescribed opioids for cancer-related pain, are rising at the same rate as in the general population is unknown. (2020-05-07)

University of Arizona researchers identify potential pathway to make opioids safer, more effective
Researchers from the UArizona College of Medicine -- Tucson Department of Pharmacology found that inhibiting heat shock protein 90 in the spinal cord enhanced the efficacy of morphine -- a finding that could be used decrease the adverse side effects of opioid therapy. (2020-05-05)

Extra payments motivate sobriety and employment among people recovering from addiction
After a yearlong study of people with opioid dependence, Johns Hopkins Medicine researchers report evidence that adding $8 an hour to their paychecks may help those in recovery stay drug free longer, as well as encourage them to get and hold regular jobs. (2020-04-20)

Study finds racial disparities in the management of pain reduction for minority children
Pain is one of the most common reasons for seeking emergency department (ED) care, yet is often poorly assessed and treated. In an effort to improve pain management among children, Monika Goyal, M.D., M.S.C.E., associate division chief of Emergency Medicine, director of Academic Affairs and Research at Children's National Hospital, led a study published in Pediatrics on racial and ethnic disparities in the management of pain among children presenting to the emergency department ED with fractures. (2020-04-20)

Prescribing an overdose: A chapter in the opioid epidemic
Research indicates that widespread opioid overprescribing contributed to the opioid epidemic. New research shows that this dangerous trend has apparently been coupled with another: inappropriate use of high-potency opioids. (2020-04-15)

Spider venom key to pain relief without side-effects
Molecules in tarantula venom could be used as an alternative to opioid pain killers for people seeking chronic pain relief. (2020-04-13)

BU researchers find opioid prescriptions linked to obesity
Two new studies from the Boston University School of Public Health (BUSPH) shed light on the relationship between obesity and the use of prescription opioids in the United States. (2020-04-02)

Researchers gain new insights into pain signaling in the brain
In a new study, researchers from the University of Copenhagen have mapped how a potent neuropeptide binds to a brain receptor involved in causing human pain. The researchers expect that the mechanism could be exploited as a new avenue for painkilling medicine. (2020-03-31)

More research on addiction potential needed for use of opioids to treat children's pain
A pair of new studies led by University of Alberta pediatricians indicate that parents are more reluctant to have opioids prescribed for their children than doctors are to prescribe them. (2020-03-25)

UC identifies populations most at risk of opiate addiction
UC's Health Geography and Disease Modeling Laboratory found that white males ages 30 to 39 were most at risk of fatal overdoses in Ohio. The study also identified 12 clusters in the state where overdose rates were highest. (2020-03-19)

Opioid withdrawal increases health risks for people who inject drugs
Experiencing the symptoms of opioid withdrawal increases the odds that a person who injects drugs will share needles or have a non-fatal overdose, according to new USC study published in the journal Drug and Alcohol Dependence. The study, which has implications for others with opioid use disorder, says medication-assisted treatment for opioid withdrawal is urgently needed and recommends that the drug buprenorphine be made available to those at risk. (2020-03-18)

A new strategy for the management of inflammatory pain
A group of researchers from Charité - Universitätsmedizin Berlin has discovered a new mechanism of long-lasting pain relief. The cell-signaling protein interleukin-4 induces a specific type of blood cell to produce endogenous opioids at the site of inflammation. The researchers' findings have been published in the Journal of Clinical Investigation (JCI) Insight*. (2020-03-16)

Ouch: Patients prescribed opioids after tooth extraction report worse pain
The use of opioids to soothe the pain of a pulled tooth could be drastically reduced or eliminated altogether from dentistry, say University of Michigan researchers. (2020-03-13)

Predicting appropriate opioid prescriptions post-cesarean delivery
Knowing the amount of opioids taken following cesarean section surgery and before discharge can inform individualized prescriptions and cut down on unnecessary, leftover pills that could be used for non-medical purposes, according to a new study from the University of Colorado Anschutz Medical Campus. (2020-03-09)

UArizona study identifies hormone that causes women to experience more pain than men
A University of Arizona Health Sciences research team led by Dr. Frank Porreca points to prolactin, a neurohormone related to lactation, as the underlying reason women experience more pain than men, and even more so when taking opioids. Their paper on the discovery was featured on the cover of Science Translational Medicine. (2020-03-04)

On the path toward non-addictive painkillers
Opioid-containing painkillers have severe side effects and have also been associated with extensive misuse, particularly in the United States. Recent findings by a team of researchers from Charité - Universitätsmedizin Berlin represent a significant step towards the development of a new generation of painkillers. Published in Scientific Reports*, their findings show that tissue acidity - or tissue pH - at the source of the pain (i.e. injury) is a crucial determinant in the development of new drugs. (2020-03-03)

'Start low, go slow' still applies for pain management, especially for older patients
Chronic pain affects a large proportion of older adults and most long-term care residents. Managing chronic pain effectively is essential but challenging, and it has been complicated by concerns about opioid abuse. (2020-03-02)

Surgeons cut opioid prescriptions by 64 percent using a new multipronged program
Surgeons in a large health-care system in central Texas implemented a pain management program that reduced longer-term opioid prescriptions by two-thirds. (2020-03-02)

Opioids for chronic non-cancer pain doubled in quarter century
A review of 24 years of global research has shown opioid prescribing doubled between 1991-2015, with demand most common for chronic conditions such as chronic lower back pain, finds University of Sydney-led research. (2020-02-25)

Study: Patients commonly prescribed opioids and antibiotics for dental conditions at EDs
A study in the March issue of The Journal of the American Dental Association from the Centers for Disease Control and Prevention found that antibiotics and opioids are frequently prescribed during emergency department visits for dental conditions, further emphasizing the need for continued efforts to combat both opioid abuse and overuse of antibiotics. (2020-02-24)

Outreach effective for opioid use disorder long-term treatment
Proactive outreach, including knocking on the doors of individuals who recently overdosed on opioids, can be an effective way to engage more people who have opioid use disorder with long-term care, according to researchers at UTHealth. (2020-02-20)

Study points to better medical diagnosis through levitating human blood
New research from the UBC's Okanagan campus, Harvard Medical School and Michigan State University suggests that levitating human plasma may lead to faster, more reliable, portable and simpler disease detection. The researchers used a stream of electricity that acted like a magnet and separated protein from blood plasma. Plasma is the clear, liquid portion of blood that remains after red blood cells, white blood cells, platelets and other cellular components are removed. (2020-02-19)

Cancer screening among women prescribed opioids
US women who take prescription opioids are no less likely to receive key cancer screenings when compared to women who are not prescribed opioids. (2020-02-18)

Telemedicine helps pregnant women tackle taboo issue
Getting pregnant while on opioids is a serious concern. Research by Medical University of South Carolina investigators reported in JAMA Network Open could ensure more women get the right help via telemedicine. (2020-02-11)

Study: Higher opioid doses fail to lessen pain
Researchers from the Department of Veterans Affairs and three universities looked at prescribing data on more than 50,000 VA patients taking opioids and found that increased doses did not improve pain control. (2020-02-05)

More than half of US opioid prescriptions for dental procedures exceeded 3-day supply recommendations from CDC 2016 guidelines
Dentists are among top prescribers of opioids in the US, however, whether their opioid prescribing exceeds guidance had not been investigated. A new study in the American Journal of Preventive Medicine indicates that more than half of opioid prescriptions issued by dentists exceed the three-day supply recommended by the CDC for acute dental pain management. The findings also show that 29% of dental patients received more powerful opioids than needed for expected post-procedure pain. (2020-02-04)

More than half of dental prescriptions for opioids exceed pain-management guidelines
A new study suggests that roughly half of the opioid prescriptions written by dentists in the United States exceed the 3-day supply recommended by federal dental pain-management guidelines. (2020-02-04)

'Levitating' proteins could help diagnose opioid abuse, other diseases
Researchers at the Precision Health Program have helped develop a new method called 'magnetic levitation' for detecting the density of proteins in the blood -- a method that could vastly improve the rate at which diseases are detected and diagnosed. (2020-02-04)

Natural herb kratom may have therapeutic effects and relatively low potential for abuse or harm, according to a user survey
Using results of a survey of more than 2,700 self-reported users of the herbal supplement kratom, sold online and in smoke shops around the U.S., Johns Hopkins Medicine researchers conclude that the psychoactive compound somewhat similar to opioids likely has a lower rate of harm than prescription opioids for treating pain, anxiety, depression and addiction. (2020-02-03)

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