Current Organ Donation News and Events

Current Organ Donation News and Events, Organ Donation News Articles.
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Fat cells may influence how the body reacts to heart failure, study shows
University of Alberta researchers have found that limiting the amount of fat the body releases into the bloodstream from fat cells when in heart failure could help improve outcomes for patients. (2021-02-23)

Lab-grown 'mini-bile ducts' used to repair human livers in regenerative medicine first
Scientists at the University of Cambridge have used a technique to grow bile duct organoids - often referred to as 'mini-organs' - in the lab and shown that these can be used to repair damaged human livers. This is the first time that the technique has been used on human organs. (2021-02-18)

UCI researchers eavesdrop on cellular conversations
An interdisciplinary team of biologists and mathematicians at the University of California, Irvine has developed a new tool to help decipher the language cells use to communicate with one another. In a paper published today in Nature Communications, the researchers introduce CellChat, a computational platform that enables the decoding of signaling molecules that transmit information and commands between the cells that come together to form biological tissues and even entire organs. (2021-02-18)

Understanding cellular clock synchronization
In humans, the disruption of circadian clocks is the cause of many metabolic diseases. Thanks to an observation tool based on bioluminescence, a research (UNIGE) were able to demonstrate that cells that compose a particular organ can be in-phase, even in the absence of the central brain clock. Indeed, the scientists managed to restore circadian function in the liver in completely arrhythmic mice, demonstrating that neurons are not unique in their ability to coordinate. (2021-02-17)

New discovery could pave the way for improved treatments for diabetes
Monash University researchers have uncovered the barrier to β-cell (beta cell) regeneration that could pave the way for improved treatments for diabetes and diseases that involve organ and tissue damage. (2021-02-12)

Pooping out miracles: scientists reveal mechanism behind fecal microbiota transplantation
In a study published in Gastroenterology - Researchers at Osaka City University and The Institute for Medical Science, The University of Tokyo, in collaboration with Brigham and Women's Hospital in Boston, report the intestinal bacterial and viral metagenome information from the fecal samples of patients with recurrent Clostridioides difficile infection (rCDI). This comprehensive analysis reveals the bacteria and phages involved in pathogenesis in rCDI, and their remarkable pathways important for the recovery of intestinal flora function. (2021-02-10)

Racial, ethnic differences in deceased organ donation
Researchers examined changes in how organ donation from deceased donors differed by race and ethnicity in the United States over time. (2021-02-10)

New method developed for 'up-sizing' mini organs used in medical research
A team of engineers and scientists has developed a method of 'multiplying' organoids: miniature collections of cells that mimic the behaviour of various organs and are promising tools for the study of human biology and disease. (2021-02-08)

Research finds COVID plasma donation is fuelled by kindness
Researchers have given new insights into why people would choose to donate Covid-19 plasma after recovering from the virus, which will be used to support the recruitment of convalescent plasma donors to help treat current Covid-19 patients and support ongoing trials. (2021-02-02)

Do promotions make consumers more generous?
Price promotions can have a positive effect on consumers' donation behavior because the monetary savings from price promotions increase consumers' perceived resources. (2021-01-22)

New trial finds arthritis drug no better than standard care for severe covid-19
Adding the arthritis drug tocilizumab to standard care for patients in hospital with severe or critical covid-19 is no better than standard care alone in improving clinical outcomes at 15 days, finds a new trial published by The BMJ today. (2021-01-20)

A mathematical study describes how metastasis starts
A scientific study carried out by the Universidad Carlos III de Madrid (UC3M) and the Universidad Complutense de Madrid (UCM) has produced a mathematical description of the way in which a tumor invades the epithelial cells and automatically quantifies the progression of the tumor and the remaining cell islands after its progression. The model developed by these researchers could be used to better understand the biophysical characteristics of the cells involved when developing new treatments for wound healing, organ regeneration, or cancer progression. (2021-01-18)

Armouring anti-cancer T cells against immunosuppressants
New 'armoured' T cells attack cancer without being suppressed by drugs given to transplant patients to avoid organ rejection. (2021-01-18)

COVID-19 outcomes for patients on immunosuppressive drugs on par with non- immunosuppressed patients
People taking immunosuppressive drugs to prevent organ transplant rejection or to treat inflammatory or autoimmune diseases do not fare worse than others on average when they are hospitalized with COVID-19. (2021-01-07)

New clues on why pregnancy may increase risk of organ transplant rejection
A research study at the University of Chicago has found that in pregnancy, while the T cell response to a fetus becomes tolerant to allow for successful pregnancy, the part of the immune system that produces antibodies (known as the humoral response) becomes sensitized, creating memory B cells that can later contribute to the rejection of a transplanted organ. (2021-01-04)

New research highlights the importance of a forgotten organ in ensuring healthy pregnancies
An international research team led by UBC has uncovered for the first time the importance of a small gland tucked behind the sternum that works to prevent miscarriage and diabetes in pregnant women. (2020-12-23)

Finding a personalized approach to treating chronic rejection after lung transplantation
By studying the roles of an inflammatory protein and antibodies in chronic rejection after lung transplantation, researchers discover possibilities for new treatments. (2020-12-17)

UMD paves the way for growing human organs for transplantation with new proof-of-concept
With the number of people who suffer from organ failures and the growing need for available organs for transplant, finding a new way to provide organs and therapeutic options to transplant patients is a critical need. In a new paper, University of Maryland researchers show for the first time that newly established stem cells from pigs could provide a solution, laying the groundwork for growing transplantable human organs. (2020-12-17)

Too many donor kidneys are discarded in U.S. before transplantation
a large portion of the discarded kidneys would function acceptably if transplanted, according to a new study from a team led by researchers in the Perelman School of Medicine at the University of Pennsylvania and the Paris Translational Research Center for Organ Transplantation. (2020-12-15)

Scientists build whole functioning thymus from human cells
Researchers at the Francis Crick Institute and University College London have rebuilt a human thymus, an essential organ in the immune system, using human stem cells and a bioengineered scaffold. Their work is an important step towards being able to build artificial thymi which could be used as transplants. (2020-12-11)

New treatment could spare early-stage rectal cancer patients life-altering side effects
A new and less invasive treatment developed by Cancer Research UK researchers is safer than standard major surgery for early-stage rectal cancer, giving patients a better quality of life with fewer life-altering side effects, results from a pilot study show. (2020-12-10)

Kidney injury in diabetic ketoacidosis linked to brain injury
Researchers have identified factors that make children with diabetic ketoacidosis more likely to experience acute kidney injury. Analyzing data from a large, multicenter clinical trial, the researchers also found that children who experience acute kidney injury are more likely to also experience subtle cognitive impairment and demonstrate lower IQ scores, suggesting a pattern of multiple organ injury. (2020-12-04)

Researchers uncover significant reason older adults are at greater risk of heart attack
A team of surgeons has found an insufficient level of the protein Sesn2 is the reason older individuals are at greater risk of heart attack, which indicates stabilizing the protein could be the answer to maintaining a healthy heart. (2020-12-03)

To increase organs available for transplant, reassess organ procurement organizations' metrics
A new paper analyzes the metrics used to evaluate organ procurement organizations and proposes three complimentary metrics to reflect more accurate and equitable performance rankings. (2020-12-02)

Risk of target organ damage in patients with masked hypertension versus sustained hypertension
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.1261, Yue Wu, Guoyue Zhang, Rong Hu and Jianlin Du from The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China consider the risk of target organ damage in patients with masked hypertension versus sustained hypertension. (2020-11-19)

3D bioprinted heart provides new tool for surgeons
Surgeons will soon have a powerful new tool for planning and practice with the creation of the first full-sized 3D bioprinted model of the human heart. (2020-11-18)

3D-printed, lifelike heart models could help train tomorrow's surgeons (video)
Full-size, realistic models of human organs could help surgeons train and practice before they cut into a patient. However, it's been challenging to make inexpensive models of a size, complexity and material that simulates human organs. Now, researchers reporting in ACS Biomaterials Science & Engineering have developed a way to 3D print a full-size model of a patient's own heart. (2020-11-18)

Bacteria convince their squid host to create a less hostile work environment
Bacteria living symbiotically within the Hawaiian bobtail squid can direct the host squid to change its normal gene-expression program to make a more inviting home, according to a new study by researchers at the University of Hawai'i. (2020-11-18)

How organ functions were shaped over the course of evolution
A large-scale study conducted by molecular biologists from Heidelberg University has yielded groundbreaking new insights into the evolution and regulation of gene expression in mammalian organs. The scientists investigated RNA synthesis and subsequent protein synthesis in the organs of humans and other representative mammals. They were able to demonstrate that the interplay of the two synthesis processes during evolution was crucial for shaping organ functions. (2020-11-11)

Simultaneous kidney transplant plus weight loss surgery safe for obese patients
A new study shows that robotic-assisted kidney transplant and weight loss surgery can be performed safely. (2020-11-10)

Do small gifts to donors increase charity appeal ROI?
Pre-giving incentives have different effects on different outcomes. The best strategy depends on what the charity wants to achieve. (2020-11-04)

Buzz kill: Ogre-faced spiders 'hear' airborne prey with their legs
In the dark of night, ogre-faced spiders with dominating big eyes dangle from a silk frame to cast a web and capture their ground prey. But these spiders also can capture insects flying behind them with precision, and Cornell University scientists have now confirmed how. (2020-10-29)

Nudges fail more often than is reported, experts warn
Research led by Queen Mary University of London has shown that despite the widespread use of behavioural interventions across society, failed interventions are surprisingly common. (2020-10-28)

Thermal vision of snakes inspires soft pyroelectric materials
Converting heat into electricity is a property thought to be reserved only for stiff materials like crystals. However, researchers--inspired by the infrared (IR) vision of snakes--developed a mathematical model for converting soft, organic structures into so-called 'pyroelectric' materials. The study, appearing October 21, 2020 in the journal Matter, proves that soft matter can be transformed into a pyroelectric material and potentially solves a long-held mystery surrounding the mechanism of IR vision in snakes. (2020-10-21)

How do snakes 'see' in the dark? Researchers have an answer
Certain species of snake -- think pit vipers, boa constrictors and pythons, among others -- are able to find and capture prey with uncanny accuracy, even in total darkness. Now scientists have discovered how these creatures are able to convert the heat from organisms that are warmer than their ambient surroundings into electrical signals, allowing them to 'see' in the dark. (2020-10-21)

Studies offer new evidence for possible link between blood type & COVID-19 susceptibility
Two studies published today in Blood Advances suggest people with blood type O may have a lower risk of COVID-19 infection and reduced likelihood of severe outcomes, including organ complications, if they do get sick. (2020-10-14)

IPK scientists discover gene that ensures slim inflorescence shape of barley
The inflorescences of grasses often have very different shapes. An international research team led by IPK has now succeeded in identifying a gene that plays a decisive role in ensuring that barley develops its characteristic slender inflorescences, called spikes. Compared to other grasses, the COMPOSITUM1 (COM1) gene has acquired a new function during grass evolution. The results have today been published in Nature Communications magazine. (2020-10-12)

Hearts harvested from pigs may soon help solve chronic shortages of these donor organs
An analysis discusses scientific breakthroughs that have overcome obstacles to cardiac xenotransplantation. (2020-10-07)

Donors more likely to give to COVID causes when font matches message
Appeals seeking donations to help fight hunger during the COVID-19 pandemic were more successful when the typeface in which the appeal was written mirrored the tone of the donation request, a new study has found. (2020-10-06)

COVID-19 antibodies in donated plasma decline within first months after symptom onset
Although there is still uncertainty about the clinical benefits and role of convalescent plasma to treat COVID-19, new research suggests that the earlier plasma is collected after the donor's recovery from COVID-19, the better, as antibodies start to disappear after three months of symptom onset. The results, which authors say may also have implications for vaccine design and for prevalence studies in communities trying to gauge how many people have recovered from the virus, are published today in the journal Blood. (2020-10-01)

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