Current Osteoporosis News and Events

Current Osteoporosis News and Events, Osteoporosis News Articles.
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TTUHSC scientist takes next step in search for bone disease treatment
For more than a decade, TTUHSC's Hiranmoy Das, Ph.D., has been investigating how KLF2 influences the development of bone and musculoskeletal diseases. Most recently, Das attempted to determine if inducing KLF2 levels in dental pulp derived stem cells will promote osteoblast and the building of new bone. His study, ''KLF2 regulates dental pulp-derived stem cell differentiation through the induction of mitophagy and altering mitochondrial metabolism,'' was published in the September issue of Redox Biology. (2020-11-20)

Potential cellular target for eliminating bone breakdown in osteoporosis found
By disabling a function of a set of cells in mice, researchers appear to have halted the process that breaks down bone, a potential boon for osteoporosis treatment (2020-11-20)

New European consensus on management of osteoporosis in advanced chronic kidney disease
This Consensus is authored by the European Renal Osteodystrophy Working Group, with expertise from the European Renal Association-European Dialysis and Transplant Association and the International Osteoporosis Foundation. It provides a succinct review of current clinical practice, and outlines practical recommendations for diagnosis, assessment of fracture risk, intervention thresholds, non-pharmacological and pharmacological intervention strategies, monitoring, and secondary fracture prevention. (2020-11-11)

Romosozumab substantially builds bone density in hip and spine
New research presented at ACR Convergence, the American College Rheumatology's annual meeting, reveals that romosozumab, an osteoporosis drug, produces substantial gains in bone mineral density in the hip and lumbar spine within one year, and that transitioning patients to a potent antiresorptive drug can lead to even more bone density gains. (2020-11-06)

Osteoporosis is underdiagnosed and undertreated in older men
A new study reveals that many older men who experience a fracture are still underdiagnosed with and undertreated for osteoporosis. Details of the study was presented at ACR Convergence, the American College Rheumatology's annual meeting. (2020-11-06)

New opportunities for detecting osteoporosis
Osteoporosis can be detected through low dose computed tomography (LDCT) imaging tests performed for lung cancer screening or other purposes. A study published in the Journal of Bone and Mineral Research found that such tests can identify large numbers of adults with low bone mineral density. (2020-11-04)

Some of the principal treatments for osteoporosis could reduce the incidence of COVID-19
A joint study by physicians at Hospital del Mar, researchers from the Hospital del Mar Medical Research Institute, Pompeu Fabra University and the Pere Virgili Health Care Park suggests that certain drugs used to treat osteoporosis are safe for COVID-19 patients and could even have a protective effect. The results support the recommendations of the scientific guidelines relating to the desirability of maintaining treatments for osteoporosis in patients with COVID-19. This is the first study of its kind in the world. (2020-11-03)

Steroid inhalers/pills for asthma linked to heightened risk of brittle bones and fractures
Taking steroid inhalers or tablets to treat asthma or control flare-ups is linked to a heightened risk of brittle bones (osteoporosis) and increased vulnerability to broken bones (fragility fractures), finds research published online in the journal Thorax. (2020-10-20)

The 'Goldilocks Day': the perfect day for kids' bone health
Not too little, not too much - Goldilocks' 'just right' approach can now assess children's daily activities as new research from the University of South Australia confirms the best make up of a child's day to maximise bone health and function in children. (2020-10-19)

COVID-19 pandemic has dramatic impact on osteoporosis management, finds new global study
A new study published prior to World Osteoporosis Day finds that the COVID-19 pandemic, which has severely affected management of non-communicable diseases, is markedly impacting the management of osteoporosis as judged by access to online FRAX fracture risk assessments. Globally, usage of the Fracture Risk Assessment Tool (FRAX®) website was on average 58% lower in April than in February 2020. (2020-10-19)

Light stimulation makes bones heavier
Tokyo Medical and Dental University (TMDU) researchers showed that laser ablation of bone inhibits expression of the osteogenesis inhibitor protein sclerostin without causing inflammation, unlike the conventional bur-drilling technique. Further investigations confirmed that this beneficial bio-stimulation works by inducing mechanical stress. These findings help advance research into the treatment of osteoporosis as well as specific enhancement of bone regrowth in orthopedic and dental surgery. (2020-10-08)

JNCCN: New research finds low bone health testing rates after prostate cancer treatment
New research in the October 2020 issue of JNCCN--Journal of the National Comprehensive Cancer Network finds the rate of bone mineral density (BMD) testing in people with prostate cancer undergoing androgen deprivation therapy (ADT) has improved in recent years, but remains low. (2020-10-07)

LED-based UV irradiation safely prevents the loss of bone and muscle mass in mice
A research team at Nagoya University has revealed that narrow-range ultraviolet (UV) irradiation using light emitting diodes (LEDs) safely increases serum vitamin D levels in aging mice and thereby prevents the loss of their bone and muscle mass. (2020-10-01)

Ocean acidification puts deep-sea coral reefs at risk of collapse
Deep-sea coral reefs face challenges as changes to ocean chemistry triggered by climate change may cause their foundations to become brittle, a study suggests. (2020-09-17)

Asthma patients given risky levels of steroid tablets
More than one quarter of asthma patients have been prescribed potentially dangerous amounts of steroid tablets, with researchers warning this puts them at greater risk of serious side-effects. (2020-09-13)

Stronger bones thanks to heat and microbiota
Osteoporosis is characterised by a deterioration of the bones and an increased risk of fractures. With one third of postmenopausal women affected, it is a major public health problem. A research team from the University of Geneva has observed that exposure to warmer ambient temperatures increases bone strength and prevents the loss of bone density. This phenomenon is linked to a change in the composition of gut microbiota and makes hopes for osteoporosis treatments. (2020-09-11)

Failure to calibrate for ethnicity in fracture epidemiology would do more harm than good
A recent article from the NEJM questioned the use of ethnicity in risk assessment algorithms, including the Fracture Risk Assessment Tool FRAX. In response to this article, experts from the International Osteoporosis Foundation have written an editorial which explains the main considerations in fracture epidemiology and risk assessment, with key messages related to the inclusion of race/ethnicity in FRAX algorithms. (2020-09-09)

Hip fracture risk linked to nanoscale bone inflexibility
New research has highlighted a preventative treatment gap in patients prone to bone fractures who are otherwise healthy. (2020-08-26)

New surgical approach for women at risk of ovarian cancer
A new two-stage surgical approach for cancer prevention is highly acceptable among premenopausal women at high risk of ovarian cancer, according to research led by Queen Mary University of London. (2020-08-24)

New research on Post-fracture Care Coordination Programs highlighted at WCO-IOF-ESCEO
After the first fragility fracture, there is a high risk of subsequent fractures, with the risk highest in the following two years. This is why secondary fracture prevention, and specifically topics related to Post-fracture Care Coordination Program (such as Fracture Liaison Service - FLS) development, are a focus of several live and pre-recorded presentations at the virtual World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2020 from August 20-22, 2020. Several of these important sessions and related abstracts are highlighted. (2020-08-21)

High intensity physical activity in early life could lead to stronger bones in adulthood
High intensity physical activity in early life might help maximise peak hip strength and prevent osteoporosis in later life, according to a study published today in JAMA Network Open from researchers at the University of Bristol. (2020-08-18)

Decline in milk consumption by children in school lunch programs may affect future health
Fluid milk consumption among children is vital, as adequate consumption of dairy products, especially during childhood, has beneficial health outcomes later in life. These benefits include reduced risk of osteoporosis, hypertension, obesity, and cancer in adulthood. Milk consumption among children has been declining for decades, so understanding and fulfilling the needs of children is crucial to reverse the decline. In an article appearing in the Journal of Dairy Science, scientists studied key contributors to increasing milk consumption among children. (2020-08-18)

Experts elucidate latest knowledge on phosphate metabolism and related disorders
Special issue of Calcified Tissue International features expert reviews that give state-of-the-art insights into the underlying mechanisms of phosphate metabolism and discuss advances in knowledge and management of hypo- and hyperphosphatemia, as well as oncogenic osteomalacia. (2020-08-17)

Oxytocin can help prevent osteoporosis
In a laboratory experiment with rats, Brazilian researchers succeeded in reversing natural processes associated with aging that lead to loss of bone density and strength. (2020-08-10)

Lung-specific risk factors may increase hip fracture risk in individuals who smoke
Smoking has been linked to a higher risk of bone fractures. Researchers have now identified certain lung-related factors that may help to predict an individual smoker's fracture risk. The findings are published in the Journal of Bone and Mineral Research. (2020-08-05)

New strategy against osteoporosis
An international research team has found a new approach that may be able to reduce bone loss in osteoporosis and maintain bone health. (2020-08-05)

Bone drug may be beneficial for knee osteoarthritis
Bisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear to be safe and beneficial for osteoarthritis patients. (2020-08-05)

Adjusting FRAX estimates to account for site of recent fracture
This important new study by Kanis et al provides probability ratios that can be used to adjust conventional FRAX estimates of fracture probability by accounting for the site of a recent fracture. (2020-07-28)

Calcium and vitamin D nutrient deficiencies lead to higher risk for osteoporosis
Research article in the journal PLoS ONE examines inadequate nutrient intake and its relationship to poor bone health, specifically risk of osteoporosis. The research was a cross sectional analysis of the U.S population from NHANES. (2020-07-28)

New review on management of osteoporosis in premenopausal women
An IOF and ECTS Working Group have published an updated review of literature published after 2017 on premenopausal osteoporosis. It outlines key information on factors affecting peak bone mass and distinguishing low bone mass from proper osteoporosis with increased fracture risk at a young age, causes of secondary osteoporosis versus idiopathic osteoporosis, as well as pregnancy-and lactation-associated osteoporosis. Also provided is a helpful flow-chart as general guidance for the management of this condition. (2020-07-27)

Study seeks to explain decline in hip fracture rates
In a paper published in the Journal of the American Medical Association Internal Medicine today, researchers showed how analysis of data from the multigenerational Framingham Osteoporosis Study may in part explain why the incidence of hip fracture in the US has declined during the last two decades. (2020-07-27)

Genetic testing could improve screening for osteoporosis
An international team of scientists has developed a novel genetic measure that could dramatically improve how doctors assess the risk of sustaining a fracture due to osteoporosis or fragility (2020-07-21)

Study shows genetic markers are useful in predicting osteoporotic fracture risk
A new study shows that genetic pre-screening could reduce the number of screening tests needed to identify individuals at risk for osteoporotic fractures. (2020-07-20)

Cardiac CT can double as osteoporosis test
Cardiac CT exams performed to assess heart health also provide an effective way to screen for osteoporosis, potentially speeding treatment to the previously undiagnosed, according to a new study. (2020-07-14)

Certain factors during infancy may affect bone health in adulthood
In a recent study, breast feeding during infancy was associated with a lower risk of lower limb fractures when children reached young adulthood, while maternal smoking was associated with a higher risk of upper limb fractures. The findings are published in the Journal of Bone and Mineral Research. (2020-07-08)

Response to stimulation in IVF may predict longer term health risks
A follow-up study of almost 20,000 young women who had a first cycle of IVF in Denmark between 1995 and 2014 indicates that those who responded poorly to treatment, with few eggs collected, are at a significantly increased risk of later age-related diseases. (2020-07-08)

New research highlights potential cardiovascular risk of novel anti-osteoporotic drug
Research presents new evidence which strengthens the plausibility that treatment with the novel anti-osteoporotic medicine, romosozumab, may lead to excess cardiovascular complications. Writing in Science Translational Medicine, the authors, from the University of Oxford's Big Data Institute and the Nuffield Department of Population Health, report that by combining data across clinical trials of romosozumab, there is some evidence that use of this drug leads to increased cardiovascular risk. (2020-06-24)

Romosozumab in osteoporosis: Considerable added benefit for women after menopause
Treatment leads to fewer vertebral fractures and to fewer other typical fractures in postmenopausal women with severe osteoporosis at high risk of fracture. (2020-06-15)

Down to the bone: Understanding how bone-dissolving cells are generated
Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones. But the intracellular mechanisms through which macrophages convert to osteoclasts are not fully understood. Recently, scientists at the Tokyo University of Science uncovered the role of a protein called Cpeb4 in this process. Their findings suggest potential therapeutic targets for bone and joint diseases like arthritis and osteoporosis. (2020-06-09)

Osteoporosis treatment may also protect against pneumonia
A recent study published in the Journal of Bone and Mineral Research found that nitrogen-containing bisphosphonates (N-BPs) such as alendronate, which are widely used to treat postmenopausal osteoporosis, are linked with lower risks of pneumonia and of dying from pneumonia. (2020-06-03)

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