Current Osteoporosis News and Events

Current Osteoporosis News and Events, Osteoporosis News Articles.
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Improved use of databases could save billions of euro in health care costs
Years of suffering and billions of euro in global health care costs, arising from osteoporosis-related bone fractures, could be eliminated using big data to target vulnerable patients, according to researchers at Lero, the Science Foundation Ireland Research Centre for Software. (2021-02-15)

Unlocking the mystery behind skeletal aging
Researchers from the UCLA School of Dentistry have identified the role a critical enzyme plays in skeletal aging and bone loss, putting them one step closer to understanding the complex biological mechanisms that lead to osteoporosis, the bone disease that afflicts some 200 million people worldwide. Findings, published online in the journal Cell Stem Cell, could hold an important key to developing more effective treatments for osteoporosis and improving the lives of an aging population. (2021-02-15)

Sweet coating for sour bones
Scientists invent a bioactive coating to improve the function of titanium implants in osteoporotic bones. This coating, comprising a chemically-modified glycan, can sequentially turn on and off inflammation on titanium surface upon implantation. This modulation stimulates the body's immune system to promote bone healing in an effective and safe way, without addition of bone-forming genes or drugs, according to the data from a rat osteoporotic model. (2021-02-12)

A 'skeletal age' calculator to predict bone fracture risk
Garvan researchers have developed a model to predict the biological age of bones that may improve the management of osteoporotic fractures. (2021-02-09)

How has Covid-19 affected the treatment of osteoporosis?
A global survey of healthcare providers by IOF, NOF and ESCEO has revealed unprecedented effects of the Covid-19 pandemic on worldwide healthcare delivery for osteoporosis. (2021-02-09)

New IOF position paper urges routine use of DXA-VFA in fracture liaison services
A new position paper by an International Osteoporosis Foundation (IOF) Fracture Working Group reviews the clinical significance of vertebral fractures, and the rationale for performing vertebral fracture assessment (VFA) routinely within post-fracture care coordination programs such as fracture liaison services (FLS). VFA is a tool available on modern DXA scanners which allows the detection of previous vertebral fractures by providing a lateral view of the spine during a regular DXA bone mineral density measurement of the hip and spine. (2021-01-28)

New benchmark set to deliver optimal osteoporosis care throughout Asia Pacific
The Asia Pacific Consortium on Osteoporosis (APCO) has today launched the first pan-Asia Pacific clinical practice standards for the screening, diagnosis, and management of osteoporosis, targeting a broad range of high-risk groups. Published in Osteoporosis International, 'The APCO Framework' comprises 16 minimum clinical standards set to serve as a benchmark for the provision of optimal osteoporosis care in the region. (2021-01-27)

UMass Amherst researchers develop technique to replicate bone-remodeling processes
A multidisciplinary research team at the University of Massachusetts Amherst's Institute for Applied Life Sciences (IALS) have developed a technique to replicate bone tissue complexity and bone-remodeling processes. This breakthrough could help researchers further their study of bone biology and assist in improving development of drugs for osteoporosis. (2021-01-26)

IOF and IFCC review calls for harmonization of assays for reference bone turnover markers
The newly published review 'Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood' describes the current status of assays for PINP and β-CTX in blood, as well as the plans for and ongoing progress towards the achievement of harmonization or standardization of commercial assays for these reference markers. (2021-01-15)

New taxonomy of non-skeletal rare disorders with impact on bone
A new paper published in Orphanet Journal of Rare Diseases by the International Osteoporosis Foundation (IOF) Skeletal Rare Diseases Working Group provides a first taxonomic classification of selected non-skeletal rare congenital disorders with an impact on bone physiology on the basis of phenotypes. The diseases have been described according to the systemic disease; genetic defect; pathophysiology of bone phenotype; and therapy, where available. (2021-01-12)

Hip fracture incidence expected to increase two-to-three fold in some Eurasian countries
A new report on the burden of osteoporosis in the Russian Federation and seven other Eurasian countries warns of increasing fracture rates due to expected demographic changes, and poor access to diagnosis and treatment. (2021-01-12)

New drug form may help treat osteoporosis, calcium-related disorders
Purdue University innovators developed a stabilized form of human calcitonin, which is a peptide drug already used for people with osteoporosis. Researchers at Purdue created a prodrug form of the peptide hormone to increase its effectiveness as an osteoporosis treatment. (2021-01-06)

Long-term study finds dozens of new genetic markers associated with lifetime bone growth
A multidisciplinary team of researchers has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing. (2021-01-06)

Obesity increases the risk of early hip fracture in postmenopausal women
Obese women have an increased risk of hip fracture earlier than others, already well before the age of 70, a new study from the University of Eastern Finland shows. The study followed 12,715 women for a period of 25 years. (2020-12-01)

TTUHSC scientist takes next step in search for bone disease treatment
For more than a decade, TTUHSC's Hiranmoy Das, Ph.D., has been investigating how KLF2 influences the development of bone and musculoskeletal diseases. Most recently, Das attempted to determine if inducing KLF2 levels in dental pulp derived stem cells will promote osteoblast and the building of new bone. His study, ''KLF2 regulates dental pulp-derived stem cell differentiation through the induction of mitophagy and altering mitochondrial metabolism,'' was published in the September issue of Redox Biology. (2020-11-20)

Potential cellular target for eliminating bone breakdown in osteoporosis found
By disabling a function of a set of cells in mice, researchers appear to have halted the process that breaks down bone, a potential boon for osteoporosis treatment (2020-11-20)

New European consensus on management of osteoporosis in advanced chronic kidney disease
This Consensus is authored by the European Renal Osteodystrophy Working Group, with expertise from the European Renal Association-European Dialysis and Transplant Association and the International Osteoporosis Foundation. It provides a succinct review of current clinical practice, and outlines practical recommendations for diagnosis, assessment of fracture risk, intervention thresholds, non-pharmacological and pharmacological intervention strategies, monitoring, and secondary fracture prevention. (2020-11-11)

Romosozumab substantially builds bone density in hip and spine
New research presented at ACR Convergence, the American College Rheumatology's annual meeting, reveals that romosozumab, an osteoporosis drug, produces substantial gains in bone mineral density in the hip and lumbar spine within one year, and that transitioning patients to a potent antiresorptive drug can lead to even more bone density gains. (2020-11-06)

Osteoporosis is underdiagnosed and undertreated in older men
A new study reveals that many older men who experience a fracture are still underdiagnosed with and undertreated for osteoporosis. Details of the study was presented at ACR Convergence, the American College Rheumatology's annual meeting. (2020-11-06)

New opportunities for detecting osteoporosis
Osteoporosis can be detected through low dose computed tomography (LDCT) imaging tests performed for lung cancer screening or other purposes. A study published in the Journal of Bone and Mineral Research found that such tests can identify large numbers of adults with low bone mineral density. (2020-11-04)

Some of the principal treatments for osteoporosis could reduce the incidence of COVID-19
A joint study by physicians at Hospital del Mar, researchers from the Hospital del Mar Medical Research Institute, Pompeu Fabra University and the Pere Virgili Health Care Park suggests that certain drugs used to treat osteoporosis are safe for COVID-19 patients and could even have a protective effect. The results support the recommendations of the scientific guidelines relating to the desirability of maintaining treatments for osteoporosis in patients with COVID-19. This is the first study of its kind in the world. (2020-11-03)

Steroid inhalers/pills for asthma linked to heightened risk of brittle bones and fractures
Taking steroid inhalers or tablets to treat asthma or control flare-ups is linked to a heightened risk of brittle bones (osteoporosis) and increased vulnerability to broken bones (fragility fractures), finds research published online in the journal Thorax. (2020-10-20)

The 'Goldilocks Day': the perfect day for kids' bone health
Not too little, not too much - Goldilocks' 'just right' approach can now assess children's daily activities as new research from the University of South Australia confirms the best make up of a child's day to maximise bone health and function in children. (2020-10-19)

COVID-19 pandemic has dramatic impact on osteoporosis management, finds new global study
A new study published prior to World Osteoporosis Day finds that the COVID-19 pandemic, which has severely affected management of non-communicable diseases, is markedly impacting the management of osteoporosis as judged by access to online FRAX fracture risk assessments. Globally, usage of the Fracture Risk Assessment Tool (FRAX®) website was on average 58% lower in April than in February 2020. (2020-10-19)

Light stimulation makes bones heavier
Tokyo Medical and Dental University (TMDU) researchers showed that laser ablation of bone inhibits expression of the osteogenesis inhibitor protein sclerostin without causing inflammation, unlike the conventional bur-drilling technique. Further investigations confirmed that this beneficial bio-stimulation works by inducing mechanical stress. These findings help advance research into the treatment of osteoporosis as well as specific enhancement of bone regrowth in orthopedic and dental surgery. (2020-10-08)

JNCCN: New research finds low bone health testing rates after prostate cancer treatment
New research in the October 2020 issue of JNCCN--Journal of the National Comprehensive Cancer Network finds the rate of bone mineral density (BMD) testing in people with prostate cancer undergoing androgen deprivation therapy (ADT) has improved in recent years, but remains low. (2020-10-07)

LED-based UV irradiation safely prevents the loss of bone and muscle mass in mice
A research team at Nagoya University has revealed that narrow-range ultraviolet (UV) irradiation using light emitting diodes (LEDs) safely increases serum vitamin D levels in aging mice and thereby prevents the loss of their bone and muscle mass. (2020-10-01)

Ocean acidification puts deep-sea coral reefs at risk of collapse
Deep-sea coral reefs face challenges as changes to ocean chemistry triggered by climate change may cause their foundations to become brittle, a study suggests. (2020-09-17)

Asthma patients given risky levels of steroid tablets
More than one quarter of asthma patients have been prescribed potentially dangerous amounts of steroid tablets, with researchers warning this puts them at greater risk of serious side-effects. (2020-09-13)

Stronger bones thanks to heat and microbiota
Osteoporosis is characterised by a deterioration of the bones and an increased risk of fractures. With one third of postmenopausal women affected, it is a major public health problem. A research team from the University of Geneva has observed that exposure to warmer ambient temperatures increases bone strength and prevents the loss of bone density. This phenomenon is linked to a change in the composition of gut microbiota and makes hopes for osteoporosis treatments. (2020-09-11)

Failure to calibrate for ethnicity in fracture epidemiology would do more harm than good
A recent article from the NEJM questioned the use of ethnicity in risk assessment algorithms, including the Fracture Risk Assessment Tool FRAX. In response to this article, experts from the International Osteoporosis Foundation have written an editorial which explains the main considerations in fracture epidemiology and risk assessment, with key messages related to the inclusion of race/ethnicity in FRAX algorithms. (2020-09-09)

Hip fracture risk linked to nanoscale bone inflexibility
New research has highlighted a preventative treatment gap in patients prone to bone fractures who are otherwise healthy. (2020-08-26)

New surgical approach for women at risk of ovarian cancer
A new two-stage surgical approach for cancer prevention is highly acceptable among premenopausal women at high risk of ovarian cancer, according to research led by Queen Mary University of London. (2020-08-24)

New research on Post-fracture Care Coordination Programs highlighted at WCO-IOF-ESCEO
After the first fragility fracture, there is a high risk of subsequent fractures, with the risk highest in the following two years. This is why secondary fracture prevention, and specifically topics related to Post-fracture Care Coordination Program (such as Fracture Liaison Service - FLS) development, are a focus of several live and pre-recorded presentations at the virtual World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2020 from August 20-22, 2020. Several of these important sessions and related abstracts are highlighted. (2020-08-21)

High intensity physical activity in early life could lead to stronger bones in adulthood
High intensity physical activity in early life might help maximise peak hip strength and prevent osteoporosis in later life, according to a study published today in JAMA Network Open from researchers at the University of Bristol. (2020-08-18)

Decline in milk consumption by children in school lunch programs may affect future health
Fluid milk consumption among children is vital, as adequate consumption of dairy products, especially during childhood, has beneficial health outcomes later in life. These benefits include reduced risk of osteoporosis, hypertension, obesity, and cancer in adulthood. Milk consumption among children has been declining for decades, so understanding and fulfilling the needs of children is crucial to reverse the decline. In an article appearing in the Journal of Dairy Science, scientists studied key contributors to increasing milk consumption among children. (2020-08-18)

Experts elucidate latest knowledge on phosphate metabolism and related disorders
Special issue of Calcified Tissue International features expert reviews that give state-of-the-art insights into the underlying mechanisms of phosphate metabolism and discuss advances in knowledge and management of hypo- and hyperphosphatemia, as well as oncogenic osteomalacia. (2020-08-17)

Oxytocin can help prevent osteoporosis
In a laboratory experiment with rats, Brazilian researchers succeeded in reversing natural processes associated with aging that lead to loss of bone density and strength. (2020-08-10)

Lung-specific risk factors may increase hip fracture risk in individuals who smoke
Smoking has been linked to a higher risk of bone fractures. Researchers have now identified certain lung-related factors that may help to predict an individual smoker's fracture risk. The findings are published in the Journal of Bone and Mineral Research. (2020-08-05)

New strategy against osteoporosis
An international research team has found a new approach that may be able to reduce bone loss in osteoporosis and maintain bone health. (2020-08-05)

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