Current Ovarian Cancer News and Events | Page 2

Current Ovarian Cancer News and Events, Ovarian Cancer News Articles.
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'Virtual biopsies' could replace tissue biopsies in future thanks to new technique
A new advanced computing technique using routine medical scans to enable doctors to take fewer, more accurate tumour biopsies, has been developed by cancer researchers at the University of Cambridge. This is an important step towards precision tissue sampling for cancer patients to help select the best treatment. In future the technique could even replace clinical biopsies with 'virtual biopsies', sparing patients invasive procedures. (2021-01-06)

In-utero exposures associated with increased risk of thyroid cancer
A recent study shows that thyroid cancer is related to in-utero exposures. (2021-01-05)

Study points the way to boost immunotherapy against breast cancer, other solid tumors
UNC Lineberger Comprehensive Cancer Center researchers report that adding a small molecule to a chimeric antigen receptor-T (CAR-T) cell therapy can help immune system T cells to effectively attack solid tumors, such as breast cancers. The boost helps recruit more immune cells into battle at the tumor site, according to the study published in the Journal of Experimental Medicine. (2020-12-31)

COVID-19's impact on cancer prevention and control in Africa
When the COVID-19 pandemic reached Africa, the continent was already struggling to deal with another public health crisis - a growing cancer epidemic characterized by more than one million new cancer cases and nearly 700,000 deaths per year. (2020-12-31)

Researchers determine factors associated with ovary removal in patients with ovarian torsion
To determine the factors associated with an increased likelihood for ovary removal during the time of surgery for ovarian torsion, researchers from Boston University School of Medicine (BUSM), conducted a retrospective study of patients from a racially diverse, urban safety-net hospital with a diagnosis of ovarian torsion during a four-and-a-half-year period. (2020-12-18)

Oral contraceptive pills protect against ovarian and endometrial cancer
A comprehensive study from Uppsala University, involving more than 250,000 women, shows that oral contraceptive use protects against ovarian and endometrial cancer. The protective effect remains for several decades after discontinuing the use. The study is published in the journal Cancer Research. (2020-12-17)

Blocking DNA repair enzyme could help treat certain cancers
Researchers at the Francis Crick Institute have found a new way to prevent some tumours from repairing their own DNA, a function that is essential for cancer cell survival. This discovery could lead to much needed new treatments for certain types of the disease. (2020-12-16)

Drug for pulmonary hypertension may become an option against cancer
In experiments by Brazilian researchers with mice and tumor cell lines, the drug showed potential to combat metastasis. The scientists are planning to conduct clinical trials with patients who are on chemotherapy. (2020-12-15)

Study finds paediatric cancer patients at no greater risk of severe COVID-19 infection
Children with cancer who test positive for COVID-19 do not appear to be at an increased risk of severe COVID-19 infection compared to healthy children, according a new UK study. (2020-12-14)

Nearly 72% of Black patients with gynecologic cancer and COVID-19 were hospitalized for the virus compared with 46 percent of non-Blacks
COVID-19 deaths among Black patients with gynecologic cancer disproportionately higher compared to non-Black patients. (2020-12-09)

Postmenopausal women with early-stage BC/low recurrence score could skip adjuvant chemo
After a median follow-up of 5.1 years, among women with lymph node-positive early-stage breast cancer and a recurrence score of 25 or lower who received adjuvant endocrine therapy with or without chemotherapy, postmenopausal patients had no added benefit from chemotherapy, while premenopausal patients who received chemotherapy had improved invasive disease-free survival (IDFS) and an early indication of improved overall survival (OS), according to data from the SWOG S1007 RxPONDER clinical trial. (2020-12-09)

The gut microbiome in polycystic ovary syndrome and its association with metabolic traits
University of Tartu researchers and their collaborators from Finland and Spain investigated the relationship between the gut microbiome and polycystic ovary syndrome. Their study revealed that women with polycystic ovary syndrome in their late reproductive years have significant microbial changes in gut-related to their metabolic health. (2020-12-08)

Researchers create framework to help determine timing of cancer mutations
UCLA researchers studying cancer evolution have created a framework to help determine which tool combinations are best for pinpointing the exact timing of DNA mutations in cancer genomes. (2020-12-07)

Potential cancer therapy may boost immune response
A new approach to cancer therapy shows potential to transform the commonly used chemotherapy drug gemcitabine into a drug that kills cancer cells in a specialized way, activating immune cells to fight the cancer, according to a study led by Cedars-Sinai Cancer investigators. (2020-12-07)

Huntsman Cancer Institute researchers identify promising drug combination for melanoma
Researchers at Huntsman Cancer Institute at the University of Utah have identified a potential drug combination to treat uveal melanoma, a type of eye cancer. Lead author Amanda Truong, trainee in the McMahon Lab at HCI and student at the U of U, explains uveal melanoma patients frequently have changes in genes called GNAQ and GNA11, which are key targets for these drugs. This study was published in the journal Clinical Cancer Research. (2020-12-03)

Chemists get peek at novel fluorescence
Rice University chemists find a second level of fluorescence in single-walled carbon nanotubes. The phenomenon may be useful in solar energy and optoelectronic applications. (2020-12-03)

Stress hormones can reawaken sleeping tumor cells, raising risk of cancer recurrence
Stress hormones and immune cells called neutrophils may contribute to the recurrence of tumors years after treatment by awakening dormant cancer cells, suggests a study of mice and data from 80 patients with lung cancer. (2020-12-02)

AI predicts which drug combinations kill cancer cells
A machine learning model developed in Finland can help us treat cancer more effectively. (2020-12-01)

City of Hope developed cancer-killing virus: activates immune system against colon cancer
A cancer-killing virus that City of Hope scientists developed could one day improve the immune system's ability to eradicate tumors in colon cancer patients, reports a new study in Molecular Cancer Therapeutics. The preclinical research is a first step to showing that City of Hope's oncolytic virus CF33 can target hard-to-treat tumors that 'handcuff' the immune system and keep T cells from activating the immune system to kill cancer cells. (2020-12-01)

Oncotarget launches special collection on breast cancer
Breast Cancer Collection published in honor of breast cancer awareness. (2020-12-01)

The number of times a person gives birth may affect how quickly they age
Having children doesn't just make you feel like you've aged overnight -- a new study led by Penn State researchers found that the number of times a person gives birth may also affect the body's physical aging process. (2020-11-30)

Gene donors at high risk for cancer received feedback
Researchers at the Estonian Genome Center at the University of Tartu studied how people at high risk for breast, ovarian or prostate cancer responses to the feedback of genetic findings. Gene donors who chose to receive results appreciated being contacted and considered the information provided to be valuable. Authors find that knowing more about people's genetic traits will significantly expand the chances of early detection of breast-, ovarian- and prostate cancer in the future. (2020-11-25)

Frozen eggs and ovarian tissue helped women conceive children after breast cancer
Women with breast cancer whose eggs or ovarian tissue were frozen had more children after their diagnosis than women who did not undergo fertility preservation using those methods before start of cancer treatment. That is according to a study by researchers at Karolinska Institutet in Sweden that is published in the journal JAMA Oncology. According to the researchers, the result highlights the importance of reproductive counseling and fertility preservation for women who are diagnosed with cancer at a young age. (2020-11-19)

Scientists discover roles for a cellular motor in cancer
Utah scientists have discovered new functions of a key cellular machine that regulates gene packaging and is mutated in 20% of human cancers. The study was published in print today in the journal Molecular Cell. (2020-11-19)

Ovarian cancer cells cooperate to metastasize
In a study on human ovarian cancer cells in mice, Harvard Medical School researchers discovered a transient, cooperative interaction between cell subpopulations that allows otherwise nonmetastatic tumor cells to become aggressive and spread. (2020-11-18)

Revolutionary CRISPR-based genome editing system treatment destroys cancer cells
Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation. The system, called CRISPR-LNPs, carries a genetic messenger (messenger RNA), which encodes for the CRISPR enzyme Cas9 that acts as molecular scissors that cut the cells' DNA. (2020-11-18)

Existing antidepressant helps to inhibit growth of cancer cells in lab animals
New research has shown that the antidepressant sertraline helps to inhibit the growth of cancer cells. The substance acts on a metabolic addiction that allows different types of cancer to grow. This is shown by a study on cell cultures and lab animals by researchers at KU Leuven. (2020-11-17)

Screening younger women for hereditary cancers may be cost effective
Population-wide screening for genetic variants linked to hereditary breast and ovarian cancer may be cost effective in women between the ages of 20 and 35, according to a study published in JAMA Network Open. (2020-11-16)

Singapore scientists identify potential new biomarker to better personalize cancer therapy
Testing for mutations in RNF43, a protein that affects key cancer cell-growth pathway Wnt, gives clinicians actionable insights to tailor treatments better. (2020-11-13)

State-level lung cancer screening rates not aligned with lung cancer burden in the US
A new study reports that state-level lung cancer screening rates were not aligned with lung cancer burden. (2020-11-12)

JNCCN study evaluates cost-effectiveness of olaparib for metastatic pancreatic cancer
New research in the November 2020 issue of JNCCN identifies metastatic pancreatic cancer patient subgroups with the highest relative cost-effectiveness from maintenance olaparib, a PARP inhibitor. (2020-11-12)

Animation reveals secrets of critical tumour protein
The latest animation technology has revealed the molecular detail of how our bodies are protected from cancer by a key 'tumour suppressor' protein called p53. (2020-11-11)

New analysis finds lung cancer screening reduces rates of lung cancer-specific death
Low-dose CT screening methods may prevent one death per 250 at-risk adults screened, according to a meta-analysis of eight randomized controlled clinical trials of lung cancer screening. Researchers at the University of Georgia analyzed the health outcomes of 90,275 patients, comparing those who were screened versus those who received usual medical care or chest x-rays. (2020-11-10)

Large-scale cancer proteomics study profiles protein changes in response to drug treatments
Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center have generated a valuable resource to aid in predicting drug sensitivity, to understand therapeutic resistance mechanisms and to identify optimal combination treatment strategies. (2020-11-05)

New insights on a common protein could lead to novel cancer treatments
A new University of Colorado Boulder-led study sheds light on a protein key to controlling how cells grow, proliferate and function and long implicated in tumor development. (2020-11-04)

Mayo Clinic study finds 1 in 8 patients with cancer harbor inherited genetic mutations
PHOENIX, Ariz. ? Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine. (2020-11-02)

Targeted inhibitor of mutated KRAS gene shows promise in lung, bowel, & other solid tumors
A novel agent that targets a mutated form of the KRAS gene - the most commonly altered oncogene in human cancers and one long considered ''undruggable'' - shrank tumors in most patients in a clinical trial with manageable side effects, researchers reported today at the 32nd EORTC-NCI-AACR Symposium on Molecular Targets and Therapeutic, which is taking place online. (2020-10-25)

Inhibitor of KRAS gene mutation shows promise in lung, bowel and other solid tumors
New results from a clinical trial of a drug that targets a cancer-causing mutation in the KRAS gene have shown that it can shrink tumours and is well-tolerated by patients. In two presentations to the 32nd EORTC-NCI-AACR cancer symposium, researchers involved in the KRYSTAL-1 phase I/II clinical trial said that adagrasib (MRTX849) showed clinical activity and manageable adverse side effects in patients with non-small cell lung cancer, colorectal cancer and other solid tumours. (2020-10-25)

Next generation BRAF inhibitor cancer drug shows promise in early patient trial
A new drug designed to work on cancers with an altered BRAF gene has shown promise in an early patient trial presented at the 32nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, which is taking place online. (2020-10-25)

Technology shines the light on ovarian cancer treatments
A Purdue University scientist and entrepreneur is working to use simple LED light to help determine if certain chemotherapy options will work for specific patients. (2020-10-22)

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