Current Ovarian Cancer News and Events | Page 25

Current Ovarian Cancer News and Events, Ovarian Cancer News Articles.
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Lung cancer: Scientists find answer to resistance
Scientists at the University of Southern Denmark have found a new strategy for overcoming the resistance, which many lung cancer patients develop towards a recent drug, which can arrest the growth of tumors. (2017-09-08)

Rucaparib boosts progression-free survival in BRCA mutant recurrent ovarian cancer
Rucaparib maintenance therapy increases progression-free survival in BRCA mutant recurrent ovarian cancer by 77%, according to late-breaking results from the ARIEL3 trial reported today at the ESMO 2017 Congress in Madrid. (2017-09-08)

Patients feel psycho-social impact of chemo more acutely than physical side effects
The preliminary results of a study to be presented at the ESMO 2017 Congress in Madrid show that socio-psychological factors have become more significant for patients today than physical side effects such as nausea and vomiting, which were among the top concerns in similar studies carried out previously. (2017-09-08)

Helping cancer survivors return to work
A new Psycho-Oncology analysis of published studies indicates that there are various employer-related factors that can help or hinder cancer survivors as they attempt to go back to work. (2017-09-07)

Blood tumor markers may warn when lung cancer patients are progressing
University of Colorado Cancer Center study suggests that rather than screening for disease, blood tumor markers could be useful in monitoring therapeutic outcomes in those with already established disease. (2017-09-06)

Recurrence of prostate cancer could be reduced thanks to exciting new discovery
Groundbreaking research could reduce the recurrence of prostate cancer in males, a new study in the journal Nature Communications reports. (2017-09-04)

ICON8 trial reaffirms standard dosing in ovarian cancer chemo
European women with ovarian cancer can safely stick to the standard three-week dosing schedule for paclitaxel rather than boosting up to a weekly dose-dense regimen, according to results of the phase III ICON8 trial to be presented at the ESMO 2017 Congress in Madrid. (2017-09-03)

Study: Drug may curb female infertility from cancer treatments
An existing drug may one day protect premenopausal women from life-altering infertility that commonly follows cancer treatments, according to a new study. (2017-09-01)

New Zealand researchers makes 'natural born killer' cell discovery
An unexpected role for a white blood cell called the Natural Killer (NK) cell -- a critical cell for ridding the body of infection and cancer, has been discovered by researchers t New Zealand's University of Otago. The NK cell is a 'vigilante' killer -- a white blood cell that destroys invaders and cancer cells through a process of 'identity card' checking. The researchers' new work shows that violent vigilante NK cells act as helper cells to start up the immune response. (2017-08-31)

Method speeds up time to analyze complex microscopic images
Researchers who typically required a week of effort to dissect cryo-electron tomography images of the 3-D structure of a single cell will now be able to do it in about an hour thanks to a new automated method developed by a team of scientists at Baylor College of Medicine and the National University of Singapore. (2017-08-31)

Researchers discover new immunotherapy combination effective at killing cancer cells
Researchers at the University of Calgary recently discovered an immunotherapy that uses existing cancer drugs in a whole new way. 'What we found is a combination of cancer therapies that complement each other in helping the immune system clear the cancer,' says Doug Mahoney, PhD. 'Our results suggest that we've been looking at these cancer drugs the wrong way -- as tumour-targeting drugs -- instead of what we now feel is their most important biological role: as immune stimulating therapy.' (2017-08-29)

Researchers discover cancer stem cell pathway in endometrial cancer
A team of Cleveland Clinic researchers have discovered a key pathway that leads to recurrence and treatment resistance in endometrial cancer, providing the potential for much needed new therapies for women with limited options. (2017-08-24)

Retaining one normal BRCA gene in breast, ovarian cancers influences patient survival
Researchers found a relationship between the genetics of tumors with germline BRCA1/2 mutations and whether the tumor retains the normal copy of the BRCA1/2 gene, and risk for primary resistance to a common chemotherapy that works by destroying cancer cells' DNA. (2017-08-22)

Many young cancer patients do not receive adequate fertility information and support
All cancer patients of reproductive age should be provided with fertility information and referrals for fertility preservation. (2017-08-21)

Few women with history of breast cancer and ovarian cancer take a recommended genetic test
More than 80 percent of women living with a history of breast or ovarian cancer at high-risk of having a gene mutation have never taken the test that can detect it. (2017-08-18)

Wistar scientists develop novel immunotherapy technology for prostate cancer
A study led by Wistar scientists describes a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA to directly encode protective antibodies against a cancer-specific protein. (2017-08-17)

Popular immunotherapy target turns out to have a surprising buddy
The majority of current cancer immunotherapies focus on PD-L1. This well-studied protein turns out to be controlled by a partner, CMTM6, a previously unexplored molecule that is now suddenly also a potential therapeutic target. Researchers from the Netherlands Cancer Institute publish these findings in the leading journal Nature on Aug. 16. (2017-08-16)

Noninvasive detection for early stage cancers from circulating DNA
A new DNA sequencing-based method could help noninvasively detect early stage cancers by analyzing fragments of genetic material circulating in the blood that originate from tumors. (2017-08-16)

Scientists develop blood test that spots tumor-derived DNA in people with early-stage cancers
In a bid to detect cancers early and in a noninvasive way, scientists at the Johns Hopkins Kimmel Cancer Center report they have developed a test that spots tiny amounts of cancer-specific DNA in blood and have used it to accurately identify more than half of 138 people with relatively early-stage colorectal, breast, lung and ovarian cancers. (2017-08-16)

Skewing the aim of targeted cancer therapies
The aim of targeted gene-based cancer therapies could often be skewed from the start. A widespread concept about how cells produce proteins proved incorrect 62 percent of the time in a new study in ovarian cancer cells on the relationship between RNA and protein levels. (2017-08-15)

From thousands of suspects, Yale researchers ferret out cancer-causing genes
A Yale-led team of researchers has identified specific gene combinations that can cause deadly brain cancer glioblastoma, using new technology that can also pinpoint triggers of other types cancers, they report Aug. 14 in the journal Nature Neuroscience. (2017-08-14)

Many women diagnosed with cancer have sexual health concerns
A new review published in the European Journal of Cancer Care indicates that, in women diagnosed with cancer, concerns pertaining to sexual health are diverse, multiple, and pervade all types and stages of cancer. (2017-08-11)

Using alternative medicine only for cancer linked to lower survival rate
Patients who choose to receive alternative therapy as treatment for curable cancers instead of conventional cancer treatment have a higher risk of death, according to researchers from the Cancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center at Yale School of Medicine and Yale Cancer Center. (2017-08-10)

Increased endometrial cancer rates found in women with high levels of cadmium
Through a five-year observational study recently published in PLOS One, researchers at the University of Missouri found that women with increased levels of cadmium -- a metal commonly found in foods such as kidneys, liver and shellfish as well as tobacco -- also had an increased risk of endometrial cancer. It's an observation the researchers hope could lead to new treatments or interventions to prevent the fourth most common cancer in women. (2017-08-09)

NYITCOM researcher discovers potential cancer treatment breakthrough
In a July issue of the journal Proceedings of the National Academy of Sciences (PNAS), Dong Zhang Ph.D., associate professor of Biomedical Sciences at New York Institute of Technology College of Osteopathic Medicine (NYITCOM) and a team of researchers detail findings that suggest new synthetic lethal interactions could inhibit the growth of tumors in mesenchymal cells, cells that develop into connective tissue such as those found in bones, soft tissues, and the central nervous system. (2017-08-08)

New study discovers 'killer peptide' that helps eliminate resistant cancer cells
A new study by University of Kentucky Markey Cancer Center researchers shows that when therapy-sensitive cancer cells die, they release a 'killer peptide' that can eliminate therapy-resistant cells. (2017-08-08)

Drug hope for acute myeloid leukemia
A new drug that strips cancer cells of their 'immortality' could help to treat patients suffering from one of the most aggressive forms of leukemia. (2017-08-08)

Mutation in prostate tumors shown to change epigenetic identity, the make-up of DNA
Prostate cancer researchers have mapped the impact of an acquired mutation that alters epigenetic identity, the make-up of DNA, in about 50 percent of patient tumor samples. The discovery also identifies a new opportunity for targeted therapy. (2017-08-07)

'Origami organs' can potentially regenerate tissues
Northwestern Medicine scientists and engineers have invented a range of bioactive 'tissue papers' made of materials derived from organs that are thin and flexible enough to even fold into an origami bird. The new biomaterials can potentially be used to support natural hormone production in young cancer patients and aid wound healing. (2017-08-07)

Blocking the back-door that cancer cells use to escape death by radiotherapy
A natural healing mechanism of the body may be reducing the efficiency of radiotherapy in breast cancer patients, according to a new study. Research led by scientists at the University of Alberta found that irradiation of breast fat (also known as adipose tissue) produces an inflammatory response that in normal circumstances promotes healing, but in cases of cancer, enables the cancer cells to survive. The team is now seeking a way to counteract the effect. (2017-07-27)

Cancer-death button gets jammed by gut bacterium
Researchers at Michigan Medicine and in China showed that a type of bacterium is associated with the recurrence of colorectal cancer and poor outcomes. They found that Fusobacterium nucleatum in the gut can stop chemotherapy from causing a type of cancer cell death called apoptosis. (2017-07-27)

Study uncovers potential 'silver bullet' for preventing and treating colon cancer
In preclinical experiments, researchers at VCU Massey Cancer Center have uncovered a new way in which colon cancer develops, as well as a potential 'silver bullet' for preventing and treating it. The findings may extend to ovarian, breast, lung, prostate and potentially other cancers that depend on the same mechanism for growth. (2017-07-26)

New therapeutic approach for difficult-to-treat subtype of ovarian cancer identified
A potential new therapeutic strategy for a difficult-to-treat form of ovarian cancer has been discovered by Wistar scientists. The findings were published online inĀ Nature Cell Biology. (2017-07-24)

COX-2 inhibitors may reverse IDO1-mediated immunosuppression in some cancers
In preclinical studies, tumors that consitutively expressed the protein indoleamine 2,3-dioxygenase (IDO1) responded to the cyclooxygenase-2 (COX-2) inhibitor celecoxib (Celebrex) and had improved infiltration of certain subsets of T cells, making them more likely to respond to anti-PD1 therapies. (2017-07-21)

Genetic predisposition to breast cancer due to non-brca mutations in ashkenazi Jewish women
Genetic mutations in BRCA1 and BRCA2 increase the risk of breast and ovarian cancer in Ashkenazi Jewish women. A new article published by JAMA Oncology examines the likelihood of carrying another cancer-predisposing mutation in BRCA1, BRCA2 or another breast cancer gene among women of Ashkenazi Jewish ancestry with breast cancer who do not carry one of the founder mutations. (2017-07-20)

Shooting the achilles heel of nervous system cancers
A cooperative research team led by researchers at Dartmouth's Norris Cotton Cancer Center devised a strategy to target cancer cells while sparing normal cells by capitalizing on vulnerabilities that are exposed only in tumor cells. These vulnerabilities are known as the 'Achilles heel' of cancer cells. Although much is known about the mutations that cause a cell to become malignant, little is known about these vulnerabilities. The team has published new findings on this topic. (2017-07-20)

New study provides BRCA mutation carriers guidance for when surgery has greatest impact
Of the women who carry the mutated BRCA1/2 genes, 45-65 percent will develop breast cancer, and 15-39 percent will develop ovarian cancer. Many women elect to undergo preventive surgeries that can significantly increase life expectancy, but can impact later fertility. However, few guidelines exist on the optimal age to undergo these procedures, and in what sequence. A new study in the INFORMS journal Decision Analysis provides insight to help physicians and patients make better-informed choices. (2017-07-19)

GW Cancer Center receives $100,000 from Avon Foundation for Patient Navigator
Mandi Pratt-Chapman, MA, associate center director for patient-centered initiatives and health equity, accepted a check from the Avon Foundation at the annual walk in Washington, DC. The money will fund a patient navigator who will provide resources to help breast cancer patients in the DC area. (2017-07-19)

Why do BRCA1 mutations cause predominantly breast and ovarian cancer?
Researchers at The University of Texas Health Science Center, now called UT Health San Antonio, report a new, previously unrecognized function of the BRCA1 gene that explains why BRCA1 gene mutation carriers are at increased risk of breast and ovarian cancer. (2017-07-18)

Is 'ovarian tissue freezing' superior to egg freezing?
Many women are turning to egg freezing to promote fertility, but what happens when it isn't an option because of special medical conditions? And, what option is there for women who want to preserve hormonal function, not just fertility? Ovarian tissue freezing can deliver these outcomes but has been considered experimental until now. According to a new study, nearly 4 out of 10 women who undergo the procedure are able to have children later on. (2017-07-13)

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