Current Pain Relief News and Events

Current Pain Relief News and Events, Pain Relief News Articles.
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A fifth of adults in Sweden report dental anxiety
In Sweden, approximately one in five adults suffers from dental anxiety or phobia. The number has decreased over time, but still an important part of the population have major problems, according to a recent doctoral thesis from the University of Gothenburg. (2021-02-22)

Dozens of new lichen species discovered in East African mountain forests
The species diversity and relationships of lichens in the genus Leptogium, which are often very difficult to identify to species, were assessed on the basis of DNA analyses using a large dataset collected during more than 10 years from East Africa. (2021-02-22)

Three longtime antibiotics could offer alternative to addictive opioid pain relievers
Three decades-old antibiotics administered together can block a type of pain triggered by nerve damage in an animal model, UT Southwestern researchers report. The finding, published online today in PNAS, could offer an alternative to opioid-based painkillers, addictive prescription medications that are responsible for an epidemic of abuse in the US. (2021-02-22)

Effective treatment for insomnia delivered in a few short phone calls
In a statewide study of adults over 60 with osteoarthritis, researchers found that effective treatment for insomnia can be delivered in a few short phone calls. (2021-02-22)

High patient uptake for text message system monitoring opioid use in real-time
Among the orthopaedic surgery patients in a study using text messaging to monitor opioid use, 61 percent of their tablets were found to be left over (2021-02-17)

Physical therapy after c-section improves outcomes
Women who received physical therapy after undergoing a cesarean section had significantly improved outcomes compared to those who did not according to a new study from University of Missouri Health Care. (2021-02-17)

New hope for treating chronic pain without opioids
According to some estimates, chronic pain affects up to 40% of Americans, and treating it frustrates both clinicians and patients--a frustration that's often compounded by a hesitation to prescribe opioids for pain. (2021-02-15)

Lipid epoxides target pain, inflammatory pathways in neurons
When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, researchers report. These modified compounds, called epo-NA5HT and epo-NADA, have much more powerful effects than the molecules from which they are derived, which also regulate pain and inflammation. (2021-02-10)

The therapeutic potential of peptides
There are more than 80 peptide drugs on the global market and about twice as many in clinical development. Due to their beneficial properties, these biomolecules play already an important role in the treatment of diseases. In Nature Reviews Drug Discovery, a team of Austrian and Australian scientists led by Markus Muttenthaler of the University of Vienna present an outlook on the latest trends in peptide drug discovery and development. (2021-02-10)

Cannabis reduces blood pressure in older adults, according to Ben-Gurion University researchers
''Older adults are the fastest growing group of medical cannabis users, yet evidence on cardiovascular safety for this population is scarce,'' says Dr. Ran Abuhasira of the BGU Faculty of Health Sciences, one of Israel's leading medical faculties, and the BGU-Soroka Cannabis Clinical Research Institute. ''This study is part of our ongoing effort to provide clinical research on the actual physiological effects of cannabis over time.'' (2021-02-08)

Findings of study comparing analgesics in acute post-trauma pain
The combination of a high?dose NSAID with paracetamol does not increase the analgesic effect compared to paracetamol alone. Researchers also found that paracetamol alone is superior to high?dose NSAID alone for posttraumatic extremity pain. (2021-02-08)

Solving chronic pain during intercourse
Women suffering from chronic conditions that result in painful intercourse represent about 10% of females of reproductive age - triggering a combined economic burden of more than $7.7 billion per year - yet scant knowledge about the origins of this pain is preventing an effective way to treat it. (2021-02-04)

How does pain experienced in everyday life impact memory?
A new study conducted out of the University of Miami indicates that brain systems related to emotional distress could underlie the negative impacts of pain on memory in healthy individuals. (2021-02-03)

In survey of those with uncontrolled asthma, half smoked cannabis
A new survey in Annals of Allergy, Asthma and Immunology shows that of those who used cannabis, about half smoked it while a third vaped - both 'inhalation routes' likely to affect one's lungs. (2021-02-02)

Opioid prescriptions remained elevated two years after critical care
Nearly 11 percent of people admitted to an ICU in Sweden between 2010 and 2018 received opioid prescriptions on a regular basis for at least six months and up to two years after discharge. That is according to a study by researchers at Karolinska Institutet published in Critical Care Medicine. The findings suggest some may become chronic opioid users despite a lack of evidence of the drugs' long-term effectiveness and risks linked to increased mortality. (2021-02-02)

Modeling the brain during pain processing
Through new research published in EPJ B, researchers show that inhibitory interneurons, which prevent chemical messages from passing between different regions of the brain, make up 20% of the circuitry in the brain required for pain processing. The discovery represents a significant advance in researchers' understanding of how our bodies and brains respond to pain. (2021-02-02)

Alternate type of surgery may prevent total knee replacement
An underused type of knee surgery in younger patients, called high tibial osteotomy, shows considerable success in reducing the need for total knee replacement, according to new research in CMAJ (Canadian Medical Association Journal) www.cmaj.ca/lookup/doi/10.1503/cmaj.200934. (2021-02-01)

Nutrition, companionship reduce pain in mice with sickle cell disease, UCI-led study finds
Researchers from the University of California, Irvine and the University of Minnesota have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin. They also discovered that duloxetine, an antidepressant that boosts serotonin levels, could be an alternative to opioids in treating chronic pain. (2021-02-01)

Enhanced recovery efforts for cesarean delivery reduce need for opioids by 80%
In a retrospective analysis of cesarean deliveries from 2015 through 2020, doctors from the Colorado Fetal Care Center at Children's Hospital Colorado found that using a wound infusion pump in combination with enhanced recovery efforts like removing urinary catheters earlier and walking around the same day of surgery can reduce opioid use by more than 80%. Also notable, researchers found a third of patients never took a single narcotic pain pill after cesarean delivery. (2021-01-28)

Pain patients who take opioids can't get in the door at over half of primary care clinics
People who take opioid medications for chronic pain may have a hard time finding a new primary care clinic that will take them as a patient if they need one, according to a new 'secret shopper' study of hundreds of clinics across the country. Stigma against long-term users of prescription opioids, likely related to the prospect of taking on a patient who might have an opioid use disorder or addiction, appears to play a role. (2021-01-27)

Controlling pain after surgery doesn't have to mean opioids, study shows
As surgeons balance the need to control their patients' post-surgery pain with the risk that a routine operation could become the gateway to long-term opioid use or addiction, a new study shows the power of an approach that takes a middle way. (2021-01-27)

Legal cannabis stores linked to fewer opioid deaths in the United States
Access to legal cannabis stores is associated with a reduction in opioid related deaths in the United States, particularly those linked to synthetic opioids such as fentanyl, finds a study published by The BMJ today. (2021-01-27)

Mouse study: gabapentin prevents harmful structural changes in spinal cord
Research led by The Ohio State University Wexner Medical Center and College of Medicine found that the widely prescribed pain-relief drug gabapentin can prevent harmful structural changes in the injured spinal cords of mice, and also block cardiovascular changes and immune suppression caused by spinal cord injury. (2021-01-26)

In ED patients with chest and abdominal pain, care delivered by physicians and APPs is si
In patients matched on complexity and acuity presenting to the emergency department with chest pain and abdominal pain, the care delivered by advanced practice providers (APPs) and emergency physicians is largely similar with respect to diagnostic test ordering and admission decisions. (2021-01-25)

Impact of patient-reported symptom information on lumbar spine MRI Interpretation
According to an open-access article in ARRS' American Journal of Roentgenology (AJR), in lumbar spine MRI, presumptive pain generators diagnosed using symptom information from brief electronic questionnaires showed almost perfect agreement with pain generators diagnosed using symptom information from direct patient interviews. (2021-01-25)

ACSL1 as a main catalyst of CoA conjugation of propionic acid-class NSAIDs in liver
Researchers from Kanazawa University have found that propionic acid-class nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, form ''conjugates'' with coenzyme A (CoA) by one of the acyl-CoA synthetases, ACSL1, in liver. These conjugates have the covalent binding ability to cellular proteins that may lead to liver injury, a rare severe side effect of NSAID treatment. This knowledge could help pharmaceutical companies to generate pain control options with fewer risks of severe side effects. (2021-01-22)

A method for calculating optimal parameters of liquid chrystal displays developed at RUDN University
A professor from RUDN University together with his colleagues from Saratov Chernyshevsky State University and D. Mendeleev University of Chemical Technology of Russia developed a method for calculating the parameters of diffraction optical elements used in LCDs. In particular, the new technology can be used to expand the angle of view while preserving high resolution and color rendition. (2021-01-22)

New technique to fast-track pain research
Scientists have for the first time established a sensory neuron model able to mass-reproduce two key sensory neuron types involved in pain sensation, enabling the easy generation of large numbers of the cells to fast-track chronic pain research. Using a new technique, researchers at Flinders University have found a way to reproduce millions of the cells, providing ample resources for the simultaneous testing of thousands of samples or potential drug libraries. (2021-01-21)

Pain-relief regimen treats trauma patients with fewer opioid drugs
A multimodal pain regimen (MMPR) designed to minimize opioid exposure and relieve acute pain associated with traumatic injury kept patient self-reported pain scores low while also reducing the daily and total amount of opioid drugs given to trauma patients. (2021-01-21)

Modified pain management strategy reduces opioid exposure to trauma patients, study shows
A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at UTHealth. (2021-01-21)

Researchers demonstrate snake venom evolution for defensive purposes
Researchers from LSTM's Centre for Snakebite Research and Interventions (CSRI) have led an international team investigating the evolutionary origins of a novel defensive trait by snakes - venom spitting - and demonstrated that defensive selection pressures can influence venom composition in snakes in a repeatable manner. (2021-01-21)

Do antidepressants help chronic back pain and osteoarthritis?
Antidepressants are commonly used worldwide to treat pain, however new research from the University of Sydney shows they offer little to no help for people suffering chronic back pain and osteoarthritis and may even cause harm. (2021-01-20)

Antidepressants largely ineffective for back pain and osteoarthritis
Antidepressant drugs are largely ineffective for back and osteoarthritis pain, despite being widely used for these conditions, suggests a review of the evidence published by The BMJ today. (2021-01-20)

US fishing and seafood industries saw broad declines last summer due to COVID-19
The US fishing and seafood sector years generated more than $200 billion in annual sales and supported 1.7 million jobs in recent years. It experienced broad declines in 2020 as a result of the COVID-19 public health crisis, according to a new NOAA Fisheries analysis released today. (2021-01-15)

Scientists reveal mechanism that causes irritable bowel syndrome
KU Leuven researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study, carried out in mice and humans, was published in Nature. (2021-01-13)

Treatment for chronic pain must address both physical and social pain
Physical pain and social pain may be more closely related than previously thought. Social pain, which typically results from interpersonal rejection or abuse, has been viewed as a non-medical response to external factors. However, recent research suggests that some physical and social stress responses may arise because of shared processing in the brain. (2021-01-12)

Post-surgical patch releases non-opioid painkiller directly to the wound
A Duke-led team of scientists has developed a bio-compatible surgical patch that releases non-opioid painkillers directly to the site of a wound for days and then dissolves away. The polymer patch provides a controlled release of a drug that blocks the enzyme COX-2 (cyclooxygenase-2,) which drives pain and inflammation. The study appears Jan. 10, 2021 in the Journal of Controlled Release. (2021-01-11)

More than half of people using cannabis for pain experience multiple withdrawal symptoms
More than half of people who use medical marijuana products to ease pain also experience clusters of multiple withdrawal symptoms when they're between uses, a new study finds. And about 10% of the patients taking part in the study experienced worsening changes to their sleep, mood, mental state, energy and appetite over the next two years as they continued to use cannabis. (2021-01-08)

Social transmission of pain, fear has different targets in mouse brain
Social contact can transfer the feeling of pain or fear in several animal species, including humans, but the exact neural mechanisms for this transmission are still being studied. (2021-01-07)

How can we help victims of torture?
Torture victims often reap less benefit from ordinary treatment. New insight might give new hope. (2021-01-06)

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