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Current Pain Relief News and Events, Pain Relief News Articles.
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New osteoarthritis genes discovered, paving way for new therapies
In the largest study of its kind, nine novel genes for osteoarthritis have been discovered by scientists from the University of Sheffield and their collaborators. (2018-03-19)

Researchers advise the use of anaesthesia in foetuses from 21 weeks of gestation
From the second trimester of pregnancy, the future baby already shows signs of pain when given a harmful stimulus or as a response to stress. In response to this confirmation, the researchers indicate the need to anaesthetise the foetus during open foetal surgery, OFS. (2018-03-16)

Medicinal cannabis is safe and effective -- it's time to reboot research
Medicinal cannabis is safe and effective in pain relief, and researchers are calling for the treatment to be properly established in our modern medical arsenal. A new special issue of the European Journal of Internal Medicine provides a comprehensive overview of current evidence for the use of cannabis and derived products in medicine, and calls for more research to improve the evidence base for its use. (2018-03-15)

Leuven researchers uncover ion channel trio that mediates painful heat sensing
Researchers at VIB and KU Leuven have uncovered a trio of complementary ion channels in sensory neurons that mediate detection of acute, harmful heat. Having three redundant molecular heat-sensing mechanisms provides a powerful fail-safe mechanism that protects against burn injuries. The seminal findings have been published today in Nature. (2018-03-14)

A new solution for chronic pain
Neuropathic pain is a chronic illness affecting 7-10 percent of the population in France and for which there is no effective treatment. Researchers at the Institute for Neurosciences of Montpellier (INSERM/Université de Montpellier) and the Laboratory for Therapeutic Innovation (CNRS/Université de Strasbourg) have uncovered the mechanism behind the appearance and continuation of pain. Based on their discovery, an innovative treatment was developed which produces, in animal subjects, an immediate, robust and long-lasting therapeutic effect on pain symptoms. (2018-03-12)

Gastrointestinal hormone measurably improved symptoms of non-alcoholic fatty liver disease
Through a randomized, double-blind, placebo-controlled phase II clinical trial, researchers at University of California San Diego School of Medicine report that small doses of NGM282, a non-tumorigenic variant of an endocrine gastrointestinal hormone, can significantly and rapidly decrease liver fat content in patients with non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). The findings represent an important proof-of-concept for the compound as there are currently no Food and Drug Administration-approved treatments for NAFLD and NASH. (2018-03-08)

Physician education and guidelines lead to drop in opioids prescribed after hand surgery
An educational session on opioid abuse and new prescription guidelines led to a 45 percent decrease in opioids prescribed after hand surgery, according to a study at Hospital for Special Surgery (HSS). The educational session was mandatory for all HSS staff involved in prescribing controlled substances. The hospital also conducted extensive research to develop guidelines for opioid prescription. (2018-03-08)

Warm showers and ball exercises may help women during childbirth
A new International Journal of Nursing Practice study demonstrates that during childbirth, women may benefit from warm showers, perineal exercises with a ball, or the combination of both strategies. (2018-03-07)

Smart glass made better, and cheaper
New 'smart glass' technology developed at the University of Delaware could make curtains and blinds obsolete and provide an instant toggle between light and dark for windshields and roof panes. While this isn't the first 'smart glass' ever developed, it is about one-tenth the price of other versions and more transparent in its transparent state and more reflective in its reflective state than competitors. (2018-03-07)

Nervous system discovery could inform stroke, pain therapies
Scientists at OHSU used advanced imaging techniques to ascertain the resting state of an acid-sensing ion channel. Acid-sensing ion channels are believed to play a role in pain sensation as well as psychiatric disorders. OHSU scientists expect the basic science research will spur new research and development into therapeutic agents targeting the channel. (2018-03-07)

Should doctors recommend acupuncture for pain?
Some see acupuncture as a safe alternative to drugs, while others argue there's no convincing evidence of clinical benefit and potential for harm. So should doctors recommend acupuncture for pain? Experts debate the issue in The BMJ today. (2018-03-07)

Pre-surgery counseling, non-opioid pain relievers shown to reduce post-surgery opioid use
Two new studies presented at the 2018 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) demonstrated that pre-operative counseling resulted in a significant decrease in opioid use after hand surgery and patients who used non-opioid pain relievers following surgery experienced a similar pain experience and benefit with less adverse events than those that received opioids. (2018-03-06)

Opioids not better at reducing pain to improve function for chronic back, knee and hip pain
Opioid medications were not better at improving pain that interfered with activities such as walking, work and sleep over 12 months for patients with chronic back pain or hip or knee osteoarthritis pain compared to nonopioid medications. (2018-03-06)

Pain's origins may be significantly different in males and females
New research from The University of Texas at Dallas supports the growing consensus that pain begins differently for men and women at the cellular level. Dr. Ted Price, Dr. Salim Megat and their colleagues in the Pain Neurobiology Research Group recently found that a specific manipulation of receptors in the nervous system for the neurotransmitter dopamine impairs chronic pain in male mice, but has no effect on females. (2018-03-06)

Researchers use health data to predict who will use opioids after hospitalization
Using electronic health record data, researchers identified patient-specific variables which were highly associated with the progression to COT. These included having a history of substance use disorder, past year receipt of a benzodiazepine, receipt of an opioid at hospital discharge and high opioid requirements during hospitalization. The model correctly predicted chronic opioid therapy in 79% of the patients and no COT correctly in 78% of the patients. (2018-03-05)

Sedative may prevent delirium in the ICU
A low dose of the sedative dexmedetomidine given at night may prevent delirium in critically ill patients, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. (2018-03-02)

A positive outlook may improve outcomes for people with chest pain
When it comes to coping with chronic angina -- chest pain or pressure that comes on when the heart isn't getting enough oxygen, usually during physical activity -- a positive outlook may help improve outcomes over time, according to a study being presented at the American College of Cardiology's 67th Annual Scientific Session. (2018-03-01)

Multimodal approach to pain management reduces opioids, prescriptions after joint replacement
A multimodal approach to pain management (using two or more different methods or medications to manage pain) rather than using opioids alone was associated with a decrease in opioid use, opioid prescriptions and common opioid-related complications in patients undergoing total hip or knee replacements, according to a study published today in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA). (2018-03-01)

More than just a cosmetic procedure -- 'tummy tuck' reduces back pain and incontinence
In addition to restoring the pre-pregnancy shape of the abdomen, abdominoplasty ('tummy tuck') surgery with muscle repair can improve back pain and urinary incontinence after childbearing, reports a study in the March issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). (2018-02-28)

Children's use of non-dental services for oral pain could be costing the NHS £2.3 million a year
Thousands of children with oral pain are being taken by parents to pharmacies and non-dental health services, including A&E, instead of their dentist, and could be costing NHS England £2.3 million a year, according to research led by Queen Mary University of London. (2018-02-28)

Holding hands can sync brainwaves, ease pain, study shows
A new study by a University of Colorado Boulder pain researcher shows that when a romantic partner holds hands with a partner in pain, their brain waves sync and her pain subsides. (2018-02-28)

Identification of brain's painkilling region could lead to opioid alternatives
Researchers from the UK & Japan have identified how the brain's natural painkilling system could be used as a possible alternative to opioids for the effective relief of chronic pain, which affects as many as one in three people at some point in their lives. (2018-02-27)

Research improves food bank effectiveness, equity
Researchers have developed computer models to improve the ability of food banks to feed as many people as possible, as equitably as possible, while reducing food waste. (2018-02-27)

Study suggests failed osteoarthritis drug could help treat opioid addiction
A study from Indiana University suggests that a drug proven safe for use in people may prevent opioid tolerance and physical dependence when used with opioid-based pain medications. (2018-02-27)

New research looks to reduce side effects in commonly used drugs
New research from The Australian National University (ANU) has drilled down to the molecular level to find similarities across six pharmaceutical drugs used in pain relief, dentist anaesthetic, and treatment of epilepsy, in a bid to find a way to reduce unwanted side-effects. (2018-02-26)

Are older adults with knee pain less active than the general population?
A new Arthritis Care & Research study found that moderate-to-vigorous physical activity levels are similarly low in older adults with symptomatic knee osteoarthritis and those from the general population without osteoarthritis or knee pain. (2018-02-22)

Gene expression study may help guide Arthritis care
Researchers who analyzed gene expression in synovial tissue samples from rheumatoid arthritis patients' joints identified different patterns that may be clinically meaningful. The findings, which are published in Arthritis & Rheumatology, indicate that the mechanisms of pain differ in patients with different synovial subtypes of rheumatoid arthritis, and they may help guide clinicians as they develop optimal treatment strategies for patients. (2018-02-22)

Research challenges use of off-label drug to treat osteoarthritis
An off-label drug prescribed to treat osteoarthritis of the hand when conventional medication has failed is ineffective, according to new research. The study shows there was no benefit in taking hydroxychloroquine to control debilitating pain when compared to a placebo (dummy substance). (2018-02-21)

Genetic study paves way for new neuropathic pain treatments
The project may pave the way for the development of more effective painkillers for the treatment of this debilitating chronic condition, which afflicts approximately 500 million people throughout the world. (2018-02-21)

More awareness, research needed on abuse risk of non-opioid painkiller
Gabapentin, a nerve pain medication and anticonvulsant sold under the brand name Neurontin and others, increasingly is being misused, necessitating prescribers to understand its abuse potential and risk profile, said Rachel Vickers Smith, Ph.D., M.P.H., assistant professor in the University of Louisville School of Nursing. (2018-02-20)

Women once considered low risk for heart disease show evidence of previous heart attack scars
Women who complain about chest pain often are reassured by their doctors that there is no reason to worry because their angiograms show that the women don't have blockages in the major heart arteries, a primary cause of heart attacks in men. But a National Institutes of Health study shows that about 8% of those women actually have scars on their heart that indicate they experienced a heart attack. (2018-02-20)

Latest palliative care findings on caregiver depression, LGBT partners, moral distress
Caregivers of patients surviving a prolonged critical illness experience high and persistent rates of depression. Losing a partner can be especially stressful for lesbian, gay, bisexual and transgender (LGBT) people. Resident physicians experience moral distress when they administer futile treatments to patients at the end of life. These are among nine major findings from the latest research on hospital palliative care, according to a study published in the Journal of Hospital Medicine. (2018-02-20)

Hydroxychloroquine no more effective than placebo for relieving osteoarthritis hand pain
Hydroxychloroquine is no more effective than placebo for relieving moderate to severe hand pain and radiographic osteoarthritis. The findings of a randomized trial are published in Annals of Internal Medicine. (2018-02-19)

Jymmin: How a combination of exercise and music helps us feel less pain
Pain is essential for survival. However, it could also slow rehabilitation, or could become a distinct disorder. How strongly we feel it depends on our individual pain threshold. Scientists at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig discovered that this threshold can be increased by a new fitness method called Jymmin. It combines working out on gym machines with free musical improvisation -- and makes us less sensitive towards physical discomfort. (2018-02-19)

Pilot study in Kenya shows link between chronic pain and glutamate consumption
Preliminary research from a small pilot study carried out in Meru, in eastern Kenya, shows a link between chronic pain and consumption of glutamate, a common flavor enhancer found in Western and non-Western diets worldwide. (2018-02-16)

New guideline warns pain benefits of medical cannabis overstated
A new medical guideline suggests Canada's family physicians should take a sober second thought before prescribing medical cannabis to most patients. Published in Canadian Family Physician, (2018-02-15)

Rock art: Life-sized sculptures of dromedaries found in Saudi Arabia
At a remarkable site in northwest Saudi Arabia, a CNRS archaeologist and colleagues from the Saudi Commission for Tourism and National Heritage have discovered camelid sculptures unlike any others in the region. They are thought to date back to the first centuries BC or AD. The find sheds new light on the evolution of rock art in the Arabian Peninsula. (2018-02-13)

Medical cannabis significantly safer for elderly with chronic pain than Opioids
The new study, published in The European Journal of Internal Medicine, found cannabis therapy is safe and efficacious for elderly patients who are seeking to address cancer symptoms, Parkinson's disease, post-traumatic stress disorder, ulcerative colitis, Crohn's disease, multiple sclerosis, and other medical issues. After six months, more than 18 percent of patients surveyed had stopped using opioid analgesics or had reduced their dosage. (2018-02-13)

Altered pain processing after opioid discontinuation
An imaging study of the brain and spinal cord published in JNeurosci reveals pain processing changes in healthy men after receiving a short-term application of a strong opioid. The research provides a plausible mechanism underlying increased pain sensitivity after discontinuation of opioid medication. (2018-02-12)

Researchers discover brain pathway that dissociates opioid addiction from analgesia
Study results may provide mechanism to make opioids safer and more efficient. (2018-02-12)

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