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Current Pathology News and Events

Current Pathology News and Events, Pathology News Articles.
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Amyloid protein transmission through neurosurgery
Amyloid beta pathology -- protein deposits in the brain - might have been transmitted by contaminated neurosurgical instruments, suggests a new UCL-led study. (2018-02-15)
Gene expression patterns may help determine time of death
International team of scientists led by Roderic Guigó at the Centre for Genomic Regulation (CRG) in Barcelona shows that changes in gene expression in different tissues can be used to predict the time of death of individuals. (2018-02-13)
Harnessing the power of genomic sequencing augments diagnosis and treatment of lymphoid cancer
A new study published in The Journal of Molecular Diagnostics has established that hybrid-capture sequencing is the method of choice for sequencing 'actionable' gene mutations across the most common forms of lymphoid cancer. (2018-02-08)
UCLA study sheds light on genetic overlap between major psychiatric disorders
Most medical conditions are largely defined by their physical symptoms. (2018-02-08)
Immune system dysfunction may occur early in Alzheimer's disease
An association between inflammation biomarkers in both blood plasma and cerebrospinal fluid (CSF) and markers of Alzheimer's disease (AD) associated pathology, has been found by researchers at the University of Colorado Anschutz Medical Campus working with the University of Wisconsin Alzheimer's Disease Research Center and the University of California San Francisco Memory and Aging Center. (2018-02-06)
Expert panel issues new guidelines for lung cancer molecular testing
Guidelines add ROS1 to list of tests matching lung cancer with targeted treatments, among other updated recommendations. (2018-01-30)
Protein YAP in early life influences adult spinocerebellar ataxia pathology
YAP and its neuronal isoform YAPdeltaC are involved in expression and regulation of genes. (2018-01-24)
Updated guideline for molecular testing and targeted therapies in lung cancer
A panel of leading experts in molecular pathology has issued new recommendations and updates to guidelines for molecular diagnostic testing of patients with lung cancer. (2018-01-23)
Inflammation drives progression of Alzheimer's
According to a study by scientists of the DZNE and the University of Bonn now published in the journal (2017-12-20)
Testing the accuracy of FDA-approved and lab-developed cancer genetics tests
Amid the debate about how much these tests should be regulated by the FDA, one question has gone unanswered: how well do LDTs and FDA-CDs perform? (2017-12-14)
Findings show potential use of artificial intelligence in detecting spread of breast cancer
Computer algorithms detected the spread of cancer to lymph nodes in women with breast cancer as well as or better than pathologists. (2017-12-12)
Using computers to detect breast cancer
Jeffrey Golden, MD, comments on new research exploring the use of computer algorithms in detecting the spread of breast cancer to lymph nodes. (2017-12-12)
Microscope using UV instead of visible light emerging as diagnostic tool
New MUSE technology obtains high-resolution images of fresh biopsies for analysis within minutes, eliminating need for conventional slides and preserving original tissue sample. (2017-12-04)
Researchers find infectious prions in Creutzfeldt-Jakob disease patient skin
In a Science Translational Medicine study published today, Case Western Reserve University School of Medicine researchers found that CJD patients also harbor infectious prions in their skin, albeit at lower levels. (2017-11-22)
AMP Iissues consensus guideline recommendations for NGS bioinformatics pipelines
The Association for Molecular Pathology, the premier global, non-profit molecular diagnostics professional society, today published 17 consensus recommendations to help clinical laboratory professionals achieve high-quality sequencing results and deliver better patient care. (2017-11-16)
Linking heart attack damage to the spleen and kidney, an integrated study of heart failure
Ganesh Halade, who uses a mouse heart attack model to research ways to prevent heart failure, has published a functional and structural compendium of the simultaneous changes taking place in the heart, spleen and kidneys in mice during the period of acute heart failure immediately following a heart attack and during the longer period of chronic heart failure that comes next. (2017-11-15)
Higher brain glucose levels may mean more severe Alzheimer's
NIA scientists have found a connection between abnormalities in how the brain breaks down glucose and the severity of the signature amyloid plaques and tangles in the brain, as well as the onset of eventual outward symptoms, of Alzheimer's disease. (2017-11-06)
Resolving traffic jams in human ALS motor neurons
A team of researchers at VIB and KU Leuven used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. (2017-10-17)
Serrated polyps plus conventional adenomas may mean higher risk for colorectal cancer
Examining more than 5,000 reports from the New Hampshire Colonoscopy Registry, A Dartmouth research team finds that individuals with both conventional adenomas as well as a subset of lesions known as serrated polyps may be at higher risk for developing colorectal cancer or high-risk adenomas that can lead to colorectal cancer, than those who have serrated polyps or high-risk adenomas alone. (2017-10-11)
Monoclonal antibody 'cocktail' halts Zika infection, according to new Miller School study
A collaborative study led by a University of Miami Miller School of Medicine researcher has found that a (2017-10-04)
Protein identified that drives initiation and growth of aggressive form of leukemia
A team led by Massachusetts General Hospital investigators has identified a new cancer-causing pathway behind most cases of an aggressive type of leukemia, findings that could lead to new targeted treatment approaches. (2017-10-03)
Computer model showed an optimal anti-amyloid treatment
One must activate amyloid degradation as soon as possible to prevent the appearance of the protein plaques in brain under Alzheimer's conditions. (2017-09-28)
Researchers describe mechanism that underlies age-associated bone loss
A major health problem in older people is age-associated osteoporosis -- the thinning of bone and the loss of bone density that increases the risk of fractures. (2017-09-22)
Rare genetic cause of peritoneal mesothelioma points to targeted therapy
BWH investigators have uncovered a new genetic cause of mesothelioma: a genetic rearrangement in the ALK gene, observed in three patients with peritoneal mesothelioma. (2017-09-14)
How liver cancer develops
Researchers at the University of Zurich and the University Hospital Zurich have discovered a major mechanism in the development of liver cancer. (2017-09-11)
Millions of novel genetic variants found in 1000 Swedish individuals
An extensive exercise to map genetic variation in Sweden has found 33 million genetic variants, 10 million of which are novel. (2017-08-25)
Comprehensive genomic analysis offers insights into causes of Wilms tumor development
Mutations involving a large number of genes converge on two pathways during early kidney development that lead to Wilms tumor. (2017-08-21)
New Pathology Atlas maps genes in cancer to accelerate progress in personalized medicine
A new Pathology Atlas is launched today with an analysis of all human genes in all major cancers showing the consequence of their corresponding protein levels for overall patient survival. (2017-08-17)
Researchers find pathologic hallmarks of Alzheimer's disease in aged chimpanzee brains
The brains of aged chimpanzees, our closest living relatives, show pathology similar to the human Alzheimer's disease (AD) brain, according to a new, multi-institution research study. (2017-08-07)
Study: History of gum disease increases cancer risk in older women
Postmenopausal women who have a history of gum disease also have a higher risk of cancer, according to a new study of more than 65,000 women that's also the first to report an association between gum disease and gallbladder cancer risk. (2017-08-01)
Kent State researchers help find pathologic hallmarks of Alzheimer's in aged chimpanzee brains
Humans are considered uniquely susceptible to Alzheimer's disease, potentially due to genetic differences, changes in brain structure and function during evolution, and an increased lifespan. (2017-08-01)
High prevalence of evidence of CTE in brains of deceased football players
Chronic traumatic encephalopathy (CTE) was diagnosed post-mortem in a high proportion of former football players whose brains were donated for research, including 110 of 111 National Football League players, according to a study published by JAMA. (2017-07-25)
A swell diagnostic method
Ludwig researchers show how a method that physically expands tissues can improve early breast cancer diagnostics and extend the capabilities of ordinary pathology labs (2017-07-17)
New clues found to common respiratory virus
Scientists have solved the structure of a protein that helps a common respiratory virus evade the immune system. (2017-06-30)
Study: Intracranial pathology not necessary for gadolinium deposition in brain tissues
New research suggests gadolinium retention may be more widespread and may be present in many more, or possibly all, patients exposed to gadolinium-based contrast agents, according to new research. (2017-06-27)
Microscope can scan tumors during surgery and examine cancer biopsies in 3-D
A new UW microscope could provide accurate real-time results during cancer-removal surgeries, potentially eliminating the 20 to 40 percent of women who have to undergo multiple lumpectomy surgeries because cancerous breast tissue is missed the first time around. (2017-06-26)
Building a better alligator: Researchers develop advanced 3-D models of bite data
The ability to bite hard is critical for crocodilians to eat their food such as turtles, wildebeest and other large prey; therefore, their anatomy is closely studied by veterinarians and paleontologists who are interested in animal movements and anatomy. (2017-06-16)
Western diet increases Alzheimer's pathology in genetically predisposed mice
Obese mice with a particular version of a gene strongly associated with Alzheimer's disease in humans show increased Alzheimer's pathology, according to new research published in eNeuro. (2017-06-12)
Scientific advances in thoracic oncology in 2016 highlighted by the IASLC
Capturing and summarizing the remarkable progress in lung cancer prevention, diagnosis, staging and treatment in 2016, the International Association for the Study of Lung Cancer (IASLC) announces the second annual publication of 'Scientific Advances in Thoracic Oncology,' available online now and in the August 2017 issue of the IASLC's Journal of Thoracic Oncology (JTO). (2017-06-08)
Review of appendix cancer cases finds over diagnosis
Lesions of the appendix are being over diagnosed as invasive cancer, report University of California San Diego School of Medicine researchers in a paper published June 7 in the journal PLOS ONE. (2017-06-07)
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