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Current Pathology News and Events

Current Pathology News and Events, Pathology News Articles.
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Early sleep loss accelerates Alzheimer's pathology in mice
Lack of sleep during adolescence and early adulthood accelerates Alzheimer's disease (AD)-related tau pathology, finds a study of male and female mice published in JNeurosci. (2018-10-15)
Early changes to synapse gene regulation may cause Alzheimer's disease
TMDU-led Japanese research revealed a role for splicing proteins in the pathology of Alzheimer's disease. (2018-10-12)
Pathology test uses AI to predict prostate cancer progression following surgery
A pathology test that applies artificial intelligence (AI) to characterize tissue samples can accurately predict clinically significant prostate cancer disease progression following surgery. (2018-10-02)
Minimally invasive autopsy improves postmortem diagnoses
Minimally invasive autopsy with CT and MRI performs as well as conventional autopsy in detecting cause of death and has the advantage of yielding more diagnoses, according to a new study. (2018-09-25)
Newly discovered enzyme is 'firing pin' for plant immunity
Just like humans, plants have an immune system that helps them fight off infections. (2018-09-17)
Otago researchers find answers as to why some people are at risk of gout
University of Otago researchers have helped characterize a genetic variant that enables new understanding of why some people are at risk of gout, a painful and debilitating arthritic disease. (2018-09-12)
Scientists identified enzyme in milk production as target for novel breast cancer drugs
VCU Massey Cancer Center researchers have identified a protein involved in milk production that stimulates the growth and spread of breast cancer and could ultimately serve as a target for novel therapies to treat breast cancer. (2018-09-11)
New tool to detect fatty liver disease before liver damage
A new test may soon be available to predict advanced fibrosis in people with non-alcoholic fatty liver disease (NAFLD). (2018-09-11)
Colorectal cancer: Tipping the scales
Tumors of the colon are among the most prevalent cancers. (2018-09-04)
Overcoming resistance
In a recent paper published in the journal Clinical Cancer Research (CCR), Carmelo Nucera, M.D., Ph.D., primary investigator in the thyroid cancer research program in the Division of Experimental Pathology in BIDMC's Department of Pathology, and colleagues investigated the role of pericytes as part of the tumor microenvironment in the subset of papillary thyroid cancers modulated by a mutation of the BRAF cancer-promoting gene. (2018-08-31)
When neurons turn against themselves
Rasmussen's encephalitis is a rare autoimmune disease that primarily affects children and can lead to seizures. (2018-08-30)
Two new truffle species discovered in Florida pecan orchards
Two new species of truffles were recently discovered on the roots of pecan trees in Florida orchards. (2018-08-23)
Researchers test autobiographical memory for early Alzheimer's detection
UA psychologist Matthew Grilli found that carriers of a gene variant that increases the risk for Alzheimer's disease have greater difficulty describing detailed memories of past events. (2018-08-23)
AMP addresses clinical relevance of DNA variants in chronic myeloid neoplasms
AMP published consensus, evidence-based recommendations to aid clinical laboratory professionals with the management of most Chronic Myeloid Neoplasms (CMNs) and development of high-throughput pan-myeloid sequencing testing panels. (2018-08-21)
Cellular escape artists help explain why some women present with advanced ovarian cancer
In a new study published recently in The Journal of Pathology, BWH investigators conducted an exhaustive analysis of 'normal' fallopian tubes from patients with HGSC. (2018-08-13)
Epigenetic reprogramming of human hearts found in congestive heart failure
Congestive heart failure is a terminal disease that affects nearly 6 million Americans. (2018-08-09)
Newly characterized molecule offers possibilities for novel Alzheimer's treatments
A study by researchers from Brigham and Women's Hospital (BWH), recently published in Acta Neuropathologica, investigated lesser-known molecules involved in tauopathies like Alzheimer's. (2018-08-02)
MGH team defines the mechanisms of action of key genetic abnormality in Ewing sarcoma
A Massachusetts General Hospital research team has used epigenome editing tools to investigate how the genetic abnormality that drives Ewing sarcoma -- the second most common bone cancer in children and young adults -- unleashes tumor growth. (2018-08-02)
MicroRNA panel can identify malignancy in indeterminate thyroid nodules
A panel of 19 microRNAs identified using next-generation sequencing could categorize indeterminate thyroid nodule samples into malignant and benign. (2018-07-26)
Contact sports associated with Lewy body disease, Parkinson's disease symptoms, dementia
There is mounting evidence that repetitive head impacts from contact sports and other exposures are associated with the neurodegenerative disease chronic traumatic encephalopathy (CTE) and dementia. (2018-07-25)
Scientists reverse aging-associated skin wrinkles and hair loss in a mouse model
Researchers have reversed wrinkled skin and hair loss, hallmarks of aging, in a mouse model. (2018-07-20)
Traumatic brain injury biomarker shows promise to support rapid damage evaluation and predict outcomes
A new study in The American Journal of Pathology found that a brain lipid molecule, lysophosphatidic acid (LPA), was significantly increased after traumatic brain injury (TBI) in a preclinical animal model. (2018-07-16)
UMN Medical School discovery could mean improved immunity against reinfections
University of Minnesota researchers have discovered a connection between the body's memory cells and a unique protein in the body called purinergic receptor P2RX7, influencing the body's long-term immune system. (2018-07-10)
Alternative splicing is crucial to muscle mass maintenance
Alternative splicing plays a crucial role in maintaining adult muscle mass, which has implications in aging and chronic disease. (2018-07-10)
Treating Alzheimer's with aspirin
A low-dose aspirin regimen may represent a new avenue for reducing Alzheimer's disease pathology, according to new research in a mouse model of the disease published in JNeurosci. (2018-07-02)
Can aspirin treat Alzheimer's?
regimen of low-dose aspirin potentially may reduce plaques in the brain, which will reduce Alzheimer's disease pathology and protect memory, according to neurological researchers at Rush University Medical Center, who published the results of their study today in the July issue of The Journal of Neuroscience. (2018-07-02)
Otago researchers' discovery unlocks secrets behind cancer drug resistance
University of Otago research provides insights into an underlying mechanism that could explain why new cancer therapies to help treat metastatic melanoma do not always work on patients, paving the way for predicting which patients will benefit from certain drugs. (2018-06-29)
Immune cells that create and sustain chronic inflammatory bowel disease identified
In preclinical experiments, Laurie Harrington and colleagues have discovered a subset of immune cells that create and sustain chronic inflammatory bowel disease. (2018-06-26)
Surgery in space
With renewed public interest in manned space exploration comes the potential need to diagnose and treat medical issues encountered by future space travelers. (2018-06-20)
Sensitive new assay finds abnormalities in tumor cells that other techniques may miss
RNA-Seq, a new next-generation assay, can detect gene fusions in solid tumor cells with high accuracy and excellent reproducibility. (2018-06-18)
On-site pathology testing in remote Australia benefits patients and cuts costs
Remote Australian Indigenous communities are benefiting from the use of portable, point of care testing devices to quickly diagnosis acutely ill patients. (2018-06-12)
Patients' self-diagnosis of personality disorders not as far off as previously believed
Purdue University researchers think the gap between a psychologists' diagnosis and a patient's self-evaluation might not be as extreme as previously perceived when both are using the same evaluation tools. (2018-06-11)
First clues to the causes of multiple sclerosis
There is still no cure for multiple sclerosis, with current treatments largely based on managing symptoms, especially accelerating recovery phases following a relapse and reducing the number and severity of relapses. (2018-05-15)
Family doctors could better detect child neglect with increased dental health training
New research now suggests that GPs lack the awareness and training to identify dental neglect in children, and therefore could miss the opportunity to share potential cases of wider abuse or neglect to other health and welfare professionals. (2018-05-10)
Antibody 'cocktail' can prevent Zika infection but is not effective for treatment of fetuses
A 'cocktail' of monoclonal antibodies that can prevent Zika virus (ZIKV) infection in primates was not effective for treatment of fetuses, according to a new collaborative study led by a University of Miami Miller School of Medicine research team. (2018-04-25)
Growing evidence that probiotics are good for your liver
Increased awareness of the importance of the microbes that live in our gut has spurred a great deal of research on the microbiome and fueled a booming probiotics industry. (2018-04-22)
New hope for treating diabetic wounds that just won't heal
New research uncovers the role of a particular protein in maintaining diabetic wounds and suggests that reversing its effects could help aid wound healing in patients with diabetes. (2018-04-21)
Researchers at LSTM take a novel approach to snakebite treatment
Researchers at LSTM's Alistair Reid Venom Research Unit are looking at treatment for snakebite in a completely different way and have shown that it is possible to treat the bite from one snake with antivenom produced from a completely different species that causes the same pathology in humans. (2018-04-19)
Active young adults with Type 1 diabetes have muscle complications
A new study from McMaster and York universities in Canada has found that poor muscle health may be a complication of Type 1 diabetes, even among active twenty-somethings. (2018-04-18)
Researchers identified a protein associated with breast cancer
Researchers at UT Southwestern Medical Center have identified a protein that is strongly associated with metastatic breast cancer and that could be a target for future therapies. (2018-04-18)
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