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Current Pelvic Organ Prolapse News and Events, Pelvic Organ Prolapse News Articles.
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ATHENA desktop human 'body' could reduce need for animal drug tests
Creating surrogate human organs, coupled with insights from highly sensitive mass spectrometry technologies, a new project is on the brink of revolutionizing the way we screen new drugs and toxic agents. ATHENA, the Advanced Tissue-engineered Human Ectypal Network Analyzer project team, is developing four human organ constructs -- liver, heart, lung and kidney -- that are based on a significantly miniaturized platform. (2014-03-26)

Research: Less invasive technique possible in vulvar cancer treatment
A team of researchers from Women & Infants Hospital of Rhode Island commanded a national stage to present the results of a study evaluating the use of sentinel lymph node dissection in women with vulvar malignancies, and then follow the patients for complications and recurrence. (2014-03-26)

Significant progress toward creating 'benchtop human' reported
Vanderbilt physicist John Wikswo reported significant progress toward creating 'Homo minutus' -- a benchtop human -- on March 26 at the Society of Toxicology meeting in Phoenix. So-called organ-on-a-chip technology is being developed to provide a better and less expensive method of drug and toxicity testing. (2014-03-26)

Effect of distance from transplant center on outcomes
Among veterans meeting eligibility for liver transplantation, greater distance from a Veterans Affairs transplant center or any transplant center was associated with lower likelihood of being put on a waitlist or receiving a transplant, and a greater likelihood of death, according to a study in the March 26 issue of JAMA. (2014-03-25)

Leading surgeons warn against media hype about tracheal regeneration
Reports of the two earliest tissue-engineered whole organ transplants using a windpipe, or trachea, created using the patient's own stem cells, were hailed as a breakthrough for regenerative medicine and widely publicized in the press. However, two leading transplant surgeons in Belgium warn of the dangers of media attention, and urge that tracheal bioengineering be demonstrated as both effective and safe before further transplants take place. Their views are published in an Editorial in The Journal of Thoracic and Cardiovascular Surgery. (2014-03-24)

Work shines light on Hox genes responsible for firefly lantern development
It's difficult to identify a single evolutionary novelty in the animal kingdom that has fascinated and intrigued mankind more than the lantern of the firefly. Yet to this day, nothing has been known about the genetic foundation for the formation and evolution of this luminescent structure. (2014-03-19)

A versatile mouse that can teach us about many diseases and drugs
Scientists from the UK and Australia have created a mouse that expresses a fluorescing 'biosensor' in every cell of its body, allowing diseased cells and drugs to be tracked and evaluated in real time and in three dimensions. (2014-03-13)

Religious beliefs of American Muslims influence attitudes toward organ donation
American Muslims who interpret negative events in life as punishment from God are less likely to believe that donating organs after death is ethical than those with a more positive outlook, according to a survey conducted by researchers from the University of Chicago's Program on Medicine and Religion. (2014-03-13)

Finding hiding place of virus could lead to new treatments
Discovering where a common virus hides in the body has been a long-term quest for scientists. Up to 80 percent of adults harbor the human cytomegalovirus, which can cause severe illness and death in people with weakened immune systems. Now, researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine report that stem cells that encircle blood vessels can be a hiding place, suggesting a potential treatment target. (2014-03-11)

Women & Infants earns March of Dimes prematurity research initiative grant
With the help of funding from the March of Dimes, James F. Padbury, M.D., is one of five scientists whose work toward discovering the causes of and reducing the rates of prematurity will be supported by March of Dimes Prematurity Research Initiative grants in 2014. (2014-03-11)

Two surgeries for pelvic prolapse found similarly effective, safe
Two surgical treatments for a form of pelvic hernia affecting women have similar rates of success and safety, scientists in a National Institutes of Health research network have found. A guided exercise therapy to strengthen pelvic muscles did not add to the benefits of either surgery. (2014-03-11)

Study finds comparable outcomes for commonly used surgeries to treat vaginal prolapse
For women undergoing surgery for vaginal prolapse and stress urinary incontinence, neither of two common repair procedures was superior to the other for functional or adverse event outcomes, and behavioral therapy with pelvic muscle training did not improve urinary symptoms or prolapse outcomes after surgery, according to a study in the March 12 issue of JAMA. (2014-03-11)

Clinical trial identifies women most likely to benefit from vaginal mesh surgery
Certain women with vaginal prolapse are most likely to benefit from undergoing vaginal mesh surgery, a technique that has become controversial and is the focus of numerous lawsuits. The findings, which are published early online in Ultrasound in Obstetrics & Gynecology, provide valuable information regarding who should and should not be considered candidates for the surgery. (2014-03-11)

Incontinence and prolapse procedures found to be comparable in women
Two common procedures to treat pelvic organ prolapse without vaginal mesh are comparable in safety and efficacy, according to research published in the latest issue of the Journal of the American Medical Association. Researchers also found that behavioral and pelvic floor muscle therapy did not improve urinary incontinence or prolapse symptoms in affected women. (2014-03-11)

New theory on cause of endometriosis
Changes to two previously unstudied genes are the centerpiece of a new theory regarding the cause and development of endometriosis, a chronic and painful disease affecting one in 10 women. The discovery by Northwestern Medicine scientists suggests epigenetic modification, a process that enhances or disrupts how DNA is read, is an integral component of the disease and its progression. (2014-03-07)

Dr. Dwight Rouse addresses rapid increase in cesarean birth rates
Dr. Dwight J. Rouse, Women & Infants Hospital of Rhode Island and The Warren Alpert Medical School of Brown University, has co-authored the first in a new, joint series called 'Obstetric Care Consensus' that is being introduced by the American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine. (2014-03-06)

Dr. Brenna Anderson contributes to expert series on GAS in pregnancy
Brenna Anderson, M.D., has published an article as part of a Clinical Expert Series in the April 2014 edition of Obstetrics & Gynecology, now available online. The article, entitled 'Puerperal Group A Streptococcal (GAS) Infection: Beyond Semmelweiss,' offers a description of the recommended approach to diagnosing and treating GAS in pregnant and postpartum women. (2014-03-06)

New constipation treatment under study for Parkinson's patients
Constipation can be another uncomfortable problem for patients with Parkinson's disease that standard treatment won't relieve, researchers say. (2014-03-03)

American Journal of Transplantation reports REGiMMUNE's transplant tolerance results
REGiMMUNE Corporation announced that the American Journal of Transplantation (AJT) has published its paper that describes a novel approach to long-term tolerance in organ transplantation with continuous administration of immune suppressants. (2014-02-28)

Reproductive coercion, intimate partner violence prevalent
Enough women experience reproductive coercion -- male behavior to control contraception and pregnancy outcomes -- that a research team now recommends health care providers address the subjects with their patients and tailor family planning discussions and recommendations accordingly. (2014-02-26)

New clues found to preventing lung transplant rejection
Drugs that broadly suppress the immune system after lung transplantation may inadvertently encourage organ rejection, according to new research at Washington University School of Medicine in St. Louis. (2014-02-25)

Stand-alone facility for organ retrieval is more efficient, less costly than hospital
Retrieving organs from brain-dead donors is logistically challenging and time consuming in hospitals. But new research shows that moving organ donors from hospitals to a regional stand-alone facility with a designated operation room for retrieving organs is more efficient and less costly. (2014-02-25)

Centers used solely for recovering organs from deceased donors may improve efficiency
Free-standing organ recovery centers could markedly improve efficiency and reduce costs associated with deceased organ donation, according to a new study published in the American Journal of Transplantation. (2014-02-25)

Biopsies before transplantation do not determine success of donated kidneys
Biopsies of donated kidneys provide little information for determining the suitability of organs for transplantation, according to two studies appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology. The findings suggest that other methods are needed when weighing whether to discard or transplant a deceased donor kidney. (2014-02-20)

Skin tumor vaccine shows promise in wild mice, rising hope for transplant patients
Papillomaviruses (linked to cervical cancer when they infect the mucosal tissue in the female reproductive tract) can also infect normal skin, where they cause warts and possibly non-melanoma skin cancer, mostly in immune-suppressed organ transplant patients. An article published on Feb. 20 in PLOS Pathogens suggests that vaccination might prevent virus-associated benign and malignant skin tumors. (2014-02-20)

Study shows that premature infants benefit from adult talk
Research led by a team at Women & Infants Hospital of Rhode Island and The Warren Alpert Medical School of Brown University has been published in the Feb. 10, 2014, online edition of Pediatrics, the official journal of the American Academy of Pediatrics. The research indicates that premature babies benefit from being exposed to adult talk as early as possible. (2014-02-20)

Clinical opinion published on use of maternal oxygen during labor
When a fetal heartbeat pattern becomes irregular during labor, many practitioners give oxygen to the mother. But questions remain whether this oxygen supplementation benefits the fetus or may actually be potentially harmful. (2014-02-20)

Targeted treatment for ovarian cancer discovered
Researchers at Women & Infants Hospital of Rhode Island have developed a biologic drug that would prevent the production of a protein known to allow ovarian cancer cells to grow aggressively while being resistant to chemotherapy. This would improve treatment and survival rates for some women. (2014-02-19)

Optimizing donor kidney distribution in the United States
Nearly 5,000 people die each year in the US waiting for a kidney transplant. Northwestern University's Sanjay Mehrotra has developed a mathematical model that simulates and optimizes donor kidney distribution. The model identifies areas for policy changes, including encouraging more sharing within states The innovative model could help ease inequities among regions in the US and ultimately help save hundreds of lives. (2014-02-14)

Harvard scientists find cell fate switch that decides liver, or pancreas?
Harvard stem cell scientists have a new theory for how stem cells decide whether to become liver or pancreatic cells during development. A cell's fate, the researchers found, is determined by the nearby presence of prostaglandin E2, a messenger molecule best known for its role in inflammation and pain. The discovery, published in the journal Developmental Cell, could potentially make liver and pancreas cells easier to generate both in the lab and for future cell therapies. (2014-02-13)

Vitamin A used in acne medicines may help autoimmune and transplant patients
The same form of Vitamin A used by teenagers to combat acne might offer benefits that are more than skin deep. That's because an international team of researchers have found that it may also help keep the immune system under control for people with autoimmune disorders or those who have received transplants. This finding was published in the February 2014 issue of the Journal of Leukocyte Biology. (2014-01-30)

Prostate cancer signal reawakens 'sleeper agent' cells in bones
Dormant prostate cancer cells in bone tissue can be reawakened to cause secondary tumors, according to new research published in Endocrine-Related Cancer. Targeting the wake-up call could prevent metastasis and improve prostate cancer survival rates. (2014-01-29)

A new toad from the 'warm valleys' of Peruvian Andes
A new species of toad was discovered hiding in the leaf litter of montane rain forest known as Peruvian Yungas ( (2014-01-17)

A CNIO study finds a 'molecular scaffolding' that maintains skin structure and organisation
A study by the Spanish National Cancer Research Centre, featured on the cover of the Journal of Cell Biology, shows how interactions between skin stem cells -- the cells responsible for the constant renewal of skin -- maintain the architecture of this organ. (2014-01-16)

Study shows elevated rates of inadequate pap tests in transgender men
A new study finds that female-to-male transgender patients had over 10 times higher odds of having an inadequate Papanicolaou test compared to female patients. The findings, by Fenway Health's Jennifer Potter, M.D., and colleagues at Fenway, Harvard Medical School and the Johns Hopkins School of Public Health, appear in the Journal of General Internal Medicine, published by Springer. (2014-01-15)

Phase II trial of Bevacizumab (Avastin) in locally advanced cervical cancer 'promising'
Addition of Bevacizumab to the existing standard of care was safe and showed promising overall results. The two- and three- year overall survival rates were 89.8 percent and 80.2 percent, respectively. (2014-01-15)

Dance and virtual reality: A promising treatment for urinary incontinence in elderly women
Virtual reality, dance and fun are not the first things that come to mind when we think of treating urinary incontinence in senior women. However, these concepts were the foundations of a promising study. (2014-01-14)

Discovery of new Tiktaalik roseae fossils reveals key link in evolution of hind limbs
The discovery of well-preserved pelves and a partial pelvic fin from Tiktaalik roseae, a 375-million-year-old transitional species between fish and the first legged animals, reveals that the evolution of hind legs actually began as enhanced hind fins. This challenges existing theory that large, mobile hind appendages were developed only after vertebrates transitioned to land. The fossils are described by scientists in the Proceedings of the National Academy of Sciences, online on Jan. 13. (2014-01-13)

Comprehensive, nonsurgical treatment improves pelvic floor dysfunction in women
University of Missouri researchers have demonstrated that a comprehensive, nonsurgical treatment significantly improves symptoms in women with pelvic floor dysfunction, a range of symptoms which include bladder and bowel problems as well as pelvic pain. (2014-01-10)

Special focus issue on sepsis
A special issue on sepsis has been released by the publisher Landes Bioscience. The articles contained in this special issue of the journal Virulence have been authored by world-class investigators and provide new insights into both the pathogen-related factors and the host defense mechanisms that lead to septic shock and contribute to its resolution or fatal outcome. (2014-01-07)

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