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Current Pelvic Organ Prolapse News and Events, Pelvic Organ Prolapse News Articles.
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Study finds HCV-positive livers safe for transplantation; Patients cured afterward
UC researchers find similar results for positive outcomes when comparing patients receiving livers infected with hepatitis C to patients who receive livers without infection. (2020-06-22)

Liver perfusion could save 7 in 10 rejected donor livers
A major study investigating the effectiveness of liver perfusion as a technique to improve the function of donor livers that would have otherwise been rejected has shown that up to 7 in every 10 could be used after just 4-6 hours of the assessment. (2020-06-17)

Brothers in arms: The brain and its blood vessels
The brain and its surrounding blood vessels exist in a close relationship. Researchers from the MPI of Immunobiology and Epigenetics have discovered how cells of the blood vessels sense the metabolic condition of the brain and alter vascular function in response. The result could be important for patients with neurodegenerative disorders such as Alzheimer's because the onset of these age-related diseases coincides with vascular defects and breakdown of vascular function in the brain. (2020-06-15)

Fewer complications after organ transplantation
A large international study coordinated by University Hospital Regensburg and Charité - Universitätsmedizin Berlin has demonstrated the safety of new cell therapy approaches for use in kidney transplant recipients. Transplant recipients were shown to require lower levels of immunosuppression in order to prevent organ rejection. This reduces the risk of side effects such as viral infections. Results from this study have been published in The Lancet.* (2020-06-10)

Transforming spleen to liver brings new hope for organ regeneration
Scientists from Nanjing University and University of Macau have transformed the spleen into a functioning liver in living mice, which could bring new hope for patients suffering from organ shortage worldwide. (2020-06-10)

High workload for ICU nurses may increase risk of organ failure for patients
For patients admitted to the intensive care unit in a hospital in Finland, increased workload for nurses and understaffing of nurses were linked with a higher likelihood that patients would experience multiple organ failure. The findings are published in the Journal of Advanced Nursing. (2020-06-03)

Benzodiazepine use before conception is linked to increased risk of ectopic pregnancy
Women who use a class of tranquilizers called benzodiazepines before becoming pregnant are at greater risk of ectopic pregnancies, according to a study of nearly 1.7 million women. The study is published in Human Reproduction. (2020-06-02)

Kidney transplantations: Better results with larger case volumes
Kidney transplantations: better results with larger case volumes. Survival probabilities increase in hospitals where kidneys are transplanted more frequently. (2020-05-25)

Kidney transplants: Better results can be inferred from a larger number of cases
Kidney transplants: Better results can be derived with larger numbers of cases. In clinics where kidneys are transplanted more frequently, the chances of survival are greater. (2020-05-22)

Advanced X-ray technology tells us more about Ménière's disease
The organ of balance in the inner ear is surrounded by the hardest bone in the body. Using synchrotron X-rays, researchers at Uppsala University have discovered a drainage system that may be assumed to play a major role in the onset of Ménière's disease, a common and troublesome disorder. These results are published in the journal Scientific Reports. (2020-05-19)

The malaria parasite P. vivax can remain in the spleen upon expression of certain proteins
The malaria parasite Plasmodium vivax can adhere to human spleen cells through the expression of so-called variant proteins. These are the conclusions of a study led by the Barcelona Institute for Global health (ISGlobal), an institution supported by 'la Caixa' and the Germans Trias i Pujol Institute (IGTP). The results, published in Proceedings of the National Academy of Sciences, suggest that this could represent an additional challenge to eliminating the disease. (2020-05-18)

The cardiac depressant factor DPP3 is predicting organ failure in burn patients
High DPP3 blood concentrations are indicating multiple organ failure and poor outcomes. sphingotec commercializes a rapid CE-IVD test for DPP3 on its proprietary point-of-care platform Nexus IB10. (2020-05-14)

Research Brief: A new approach to averting inflammation caused by COVID-19
U of M Twin Cities student Molly Gilligan studies the body's inflammatory response to the SARS-CoV-2. (2020-05-12)

Immune system discovery paves way to lengthen organ transplant survival
A new discovery in mice shows the innate immune system has 'memory,' previously thought to be a unique feature of the adaptive immune system. Blocking this memory prevented transplanted organs from being rejected, providing a way to more specific drugs that could lengthen organ transplant survival. (2020-05-08)

Study reveals impact of 'soft opt-out' system for organ donation
Research published in Anaesthesia suggests that a 'soft opt-out' system may increase consent rates for organ donation after death, which could boost the number of organs available for transplantation. (2020-05-06)

Researchers identify a fundamental protein to guarantee liver regeneration
Researchers from the University of Barcelona and the CELLEX Biomedical Research Centre from IDIBAPS, in collaboration with scientists from the University of Sydney, University of London and the Research Institute Sant Joan de Déu, have identified in a study with mice a protein which is fundamental to guarantee the restoration and regeneration of the liver after a transplant or hepatic surgery. (2020-05-06)

New staining technique visualizes whole organs and bodies
A RIKEN research team in Japan has established an optimized three-dimensional (3D) tissue-staining and observation technique based on existing tissue clearing technology. The study details how the new technique can be used to stain tissue and label cells in mouse brains, human brains, and whole marmoset bodies. This technique will allow detailed anatomical analysis and whole-organ comparisons between species at the cellular level. (2020-04-27)

'Frailty' from age 40 -- what to look out for
With all eyes on avoiding major illness this year, health researchers are urging people as young as 40 to build physical and mental health to reduce or even avoid 'frailty' and higher mortality risk. A new study published online in BMC Geriatrics found 'pre-frailty occurs in 45% of people aged 40-49 - which is about the same percentage of people aged 70-75. (2020-04-15)

An antibody treatment combats life-threatening sepsis in rodents
Sepsis -- the body's extreme and organ-damaging response to severe infections -- is a major contributor to death in patients battling infectious disease. (2020-04-15)

When fathers are pregnant
Reproduction is still one of the greatest mysteries in nature. Pregnancies are usually carried out by the female sex. Only in pipefishes and seahorses males are the pregnant sex. An international team of scientists led by the GEOMAR Helmholtz Centre for Ocean Research Kiel has deciphered the complex modifications of their immune system that enabled male pregnancy. The results have now been published in Proceedings of the National Academy of Sciences (PNAS). (2020-04-13)

Ear's inner secrets revealed with new technology
What does it actually look like deep inside our ears? This has been very difficult to study as the inner ear is protected by the hardest bone in the body. But with the help of synchrotron X-rays, it is now possible to depict details inside the ear three-dimensionally. Together with Canadian colleagues, researchers from Uppsala University have used the method to map the blood vessels of the inner ear. (2020-04-09)

Researchers use nanotechnology to develop new treatment for endometriosis
Scientists have developed a precise, nanotechnology-based treatment to alleviate the pain and fertility problems associated with endometriosis, a common gynecological condition in women of childbearing age. (2020-04-06)

Needing a change? Researchers find GABA is the key to metamorphosis
Researchers led by the University of Tsukuba found that the neurotransmitter GABA is an essential regulator of metamorphosis in the sea squirt Ciona intestinalis. Larvae defective in GABA synthesis and transport failed to initiate metamorphosis and did not display adult organ growth. GABA positively regulated neurons expressing the reproductive maturation hormone GnRH, which is required for the key step of metamorphosis. These findings will help researchers to fully characterize the cellular changes underlying metamorphosis and explore pathway conservation among animals. (2020-03-31)

Stem cells and nerves interact in tissue regeneration and cancer progression
Researchers at the University of Zurich show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demonstrate that cancer stem cells likewise establish contacts with nerves. Targeting tumor innervation could thus lead to new cancer therapies. (2020-03-23)

How curved are your bones?
Researchers find smart bones curve to protect against fracture. (2020-03-13)

Early blood marker may predict future risk of kidney transplant failure
In a study of kidney transplant recipients, the composition of certain immune cells in the blood 1 year after kidney transplantation was linked with a patient's subsequent risk of kidney transplant failure. (2020-03-12)

Fatal overproduction of antibodies
Bone marrow plasma cells produce antibodies. These comprise two long and two short protein chains. The pathological proliferation of plasma cells can lead to an overproduction of the short chains. These associate to fibrils and deposit in organs. The result is fatal organ failure. A research team from the Technical University of Munich (TUM) and Heidelberg University has now identified the mutation behind the disease in a patient. (2020-03-10)

Mayo Clinic-led study links obesity with pancreatitis
A study by researchers at Mayo Clinic in Arizona published in the The Journal of Clinical Investigation has found that obesity is not only implicated in chronic diseases such as diabetes, but also in sudden-onset diseases such as pancreatitis. (2020-03-09)

Sphingotec's endothelial function biomarker bio-ADM® improves risk stratification of sepsis patients at ICUs
New study data show that monitoring blood levels of sphingotec's endothelial function biomarker bio-ADM® on top of guideline parameter lactate improves risk stratification of sepsis patients admitted to intensive care units. (2020-03-05)

Wake Forest scientists create world's most sophisticated lab model of the human body
Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) have developed the world's most sophisticated laboratory model of the human body, creating a system of miniaturized organs that can be used to detect harmful and adverse effects of drugs before they are prescribed to patients. (2020-03-02)

New tool aids patients in selecting a transplant center
A new website developed by researchers at Hennepin Healthcare Research Institute (HHRI) and the University of Minnesota (UMN) is making it easier for organ transplant candidates to choose which transplant center is right for them. The website, transplantcentersearch.org, was developed for candidates seeking kidney, liver, heart and lung transplants. Data for liver centers is currently live. Data for other organs will soon be available. (2020-02-24)

Deciphering the mechanism that determines organ size and shape
The study, published in the journal Developmental Cell and performed in Drosophila, unravels how developmental genes regulate organ size and proportions. Researchers at IRB Barcelona demonstrate that the size and patterning of a given organ are regulated by different mechanisms. Given the high genetic and mechanistic conservation between flies and humans, these discoveries pave the way for new research lines into congenital malformations and other diseases (2020-02-21)

Survey finds Americans strongly support organ and tissue donation for research
A strong majority of Americans agree that organ and tissue donation for research contributes to health and medical breakthroughs and acknowledge significant shortfalls for donation. This is according to a new survey released today commissioned by Research!America in partnership with The National Disease Research Interchange (NDRI). (2020-02-18)

First Swedish transplant of uterus from deceased donor
The Swedish team responsible for uterine transplantation research has, for the first time, transplanted a uterus from a deceased donor. The operation proceeded without complications and the recipient is doing well. (2020-02-17)

Transparent human organs allow 3D maps at the cellular level
For the first time, researchers managed to make intact human organs transparent. Using microscopic imaging they could revealed underlying complex structures of the see-through organs at the cellular level. Resulting organ maps can serve as templates for 3D-bioprinting technologies. In the future, this could lead to the creation of on demand artificial organs for many patients in need. The findings published in Cell joined forces from Helmholtz Zentrum München, Ludwig Maximilians University Munich (LMU), and Technical University of Munich (TUM). (2020-02-13)

UIC researchers find unique organ-specific signature profiles for blood vessel cells
Researchers have discovered that endothelial cells have unique genetic signatures based on their location in the body. (2020-02-13)

Novel drug therapy shows promise for quality, quantity of kidneys available for transplant
Researchers from Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center (UH), Cleveland Clinic and Lifebanc (a Northeast Ohio organ-procurement organization) have developed a new way to preserve donated kidneys -- a method that could extend the number and quality of kidneys available for transplant, saving more people with end-stage renal disease, more commonly known as 'kidney failure.' (2020-02-11)

UC research could help reduce disease incidence in organ donors
Researchers at the University of Cincinnati are among the first to adopt genotyping that helps identify and predict the risk accompanying individuals wishing to donate a kidney. Those who are high-risk of developing disease can be removed from the pool of potential donors which will reduce their chances of developing kidney disease. (2020-02-11)

In vitro organ model research trends
Two distinct approaches are predominantly used to recapitulate physiologically relevant in vitro human organ models. (2020-02-07)

iPS cells to regulate immune rejection upon transplantation
Scientists suggest a new strategy that uses induced pluripotent stem cells (iPSCs) to regulate immune reaction to transplanted tissues. (2020-02-06)

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