Current Periodontal Disease News and Events

Current Periodontal Disease News and Events, Periodontal Disease News Articles.
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Periodontal disease increases risk of major cardiovascular events
People with periodontitis are at higher risk of experiencing major cardiovascular events, according to new research from Forsyth Institute and Harvard University scientists and colleagues. (2021-02-21)

Bleeding gums may be a sign you need more vitamin C in your diet
Bleeding of the gums on gentle probing, or gingival bleeding tendency, and also bleeding in the eye, or retinal hemorrhaging, were associated with low vitamin C levels in the bloodstream. (2021-02-01)

Esophageal cancer patients show abundance of oral pathogens
DNA from various oral bacterial pathogens has been found in tumors from esophageal cancer patients. Researchers led by Tokyo Medical and Dental University (TMDU) examined bacterial pathogens in plaque and saliva from esophageal cancer patients, determining that a prevalence of three species in particular, along with alcohol consumption, is associated with a high risk of esophageal cancer. Screening of oral pathogens could therefore be used for early disease detection. (2021-01-14)

To understand periodontal disease, researchers examine the surprising behavior of T cells
In diseases characterized by bone loss -such as periodontitis, rheumatoid arthritis, and osteoporosis- there is a lot that scientists still don't understand. What is the role of the immune response in the process? What happens to the regulatory mechanisms that protect bone? In a paper published recently in Scientific Reports, researchers from the Forsyth Institute and the Universidad de Chile describe a mechanism that unlocks a piece of the puzzle. (2021-01-11)

Dental experts discover biological imbalance is the link between gum and kidney disease
An imbalance of the body's oxygen producing free radicals and its antioxidant cells could be the reason why gum disease and chronic kidney disease affect each other, a new study led by the University of Birmingham has found. (2021-01-05)

Gum disease-causing bacteria borrow growth molecules from neighbors to thrive
The human body is filled with friendly bacteria. However, some of these microorganisms, such as Veillonella parvula, may be too nice. These peaceful bacteria engage in a one-sided relationship with pathogen Porphyromonas gingivalis, helping the germ multiply and cause gum disease, according to a new University at Buffalo-led study. (2021-01-05)

Molecules derived from omega-3 can regenerate inflamed periodontal tissue
An in vitro study by a Brazilian researcher shows that maresin and resolvin synthesized from fatty acid stimulate periodontal ligament stem cells even in the presence of inflammation (2020-12-16)

How poor oral hygiene may result in metabolic syndrome
Researchers from TMDU identified a novel mechanism by which periodontal disease may cause metabolic syndrome. By studying patients with metabolic syndrome, the researchers demonstrated high antibody titers against Porphyromonas gingivalis, the bacterium causing periodontal disease. In a mouse model, the researchers then showed that infection with this bacterium causes systemic insulin resistance and metabolic dysfunction in skeletal muscle by altering the gut microbiome. This study shows the effect periodontal disease can have on the entire body. (2020-12-08)

Link between periodontitis and cardiovascular disease in individuals with rheumatoid arthritis
Rates of both periodontal disease and cardiovascular disease are elevated in individuals with rheumatoid arthritis. New research published in Arthritis & Rheumatology suggests that immune responses to certain bacteria that cause periodontal disease may play a role in patients' higher cardiovascular disease risk. (2020-11-18)

Mechanism linking gum disease to heart disease, other inflammatory conditions discovered
The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind that association has, until now, remained a mystery. This month, a team of scientists and clinicians led by the University of Toronto's Faculty of Dentistry say they've found the reason why -- and it's related to the body's own hyperactive immune response. The findings were published in October in the Journal of Dental Research. (2020-10-20)

Light stimulation makes bones heavier
Tokyo Medical and Dental University (TMDU) researchers showed that laser ablation of bone inhibits expression of the osteogenesis inhibitor protein sclerostin without causing inflammation, unlike the conventional bur-drilling technique. Further investigations confirmed that this beneficial bio-stimulation works by inducing mechanical stress. These findings help advance research into the treatment of osteoporosis as well as specific enhancement of bone regrowth in orthopedic and dental surgery. (2020-10-08)

Forsyth researchers demonstrate how changing the stem cell response to inflammation may reverse periodontal disease
In new research published recently in the journal Frontiers in Immunology, Forsyth Institute scientists have discovered that a specific type of molecule may stimulate stem cells to regenerate, reversing the inflammation caused by periodontal disease. (2020-10-02)

Pathogens in the mouth induce oral cancer
Pathogens found in tissues that surround the teeth contribute to a highly aggressive type of oral cancer, according to a study published 1st October in the open-access journal PLOS Pathogens by Yvonne Kapila of the University of California, San Francisco, and colleagues. In addition, the study showed that oral cancer formation mediated by the pathogens is inhibited by a bacteriocin - an antimicrobial and probiotic peptide that is produced by bacteria. (2020-10-01)

Oral radiography can reveal chronic coronary artery disease
A study found a link between carotid artery calcification observable in radiographs and coronary artery disease as well as several oral infections. (2020-09-16)

Gum disease may raise risk of some cancers
People who have periodontal (gum) disease may have a higher risk of developing some forms of cancer, suggests a letter published in the journal Gut detailing a prospective study. (2020-07-20)

Research Brief: A new approach to averting inflammation caused by COVID-19
U of M Twin Cities student Molly Gilligan studies the body's inflammatory response to the SARS-CoV-2. (2020-05-12)

Immune-regulating drug improves gum disease in mice
A drug that has life-extending effects on mice also reverses age-related dental problems in the animals, according to a new study published today in eLife. (2020-04-28)

Improving the treatment of periodontitis
For the first time, researchers from Charité -- Universitätsmedizin Berlin have shown that a unicellular parasite commonly found in the mouth plays a role in both severe tissue inflammation and tissue destruction. (2020-04-15)

The building blocks of gum disease
Research focusing on the bacteria responsible for gum disease has revealed the unique assembly mechanism of its pili -- adhesive filaments used for attachment. (2020-04-13)

The microbes in your mouth, and a reminder to floss and go to the dentist
Most people know that good oral hygiene - brushing, flossing, and regular dental visits - is linked to good health. Colorado State University microbiome researchers offer fresh evidence to support that conventional wisdom, by taking a close look at invisible communities of microbes that live in every mouth. Their study found a correlation between people who did not visit the dentist regularly and increased presence of a pathogen that causes periodontal disease. (2020-03-02)

Vaping changes oral microbiome, increasing risk for infection
Using e-cigarettes alters the mouth's microbiome -- the community of bacteria and other microorganisms -- and makes users more prone to inflammation and infection, finds a new study led by researchers at NYU College of Dentistry. (2020-02-26)

Age at menopause not linked to conventional cardiovascular disease risk factors
The age at which a woman's periods stop, and the menopause starts, doesn't seem to be linked to the development of the risk factors typically associated with cardiovascular disease, suggests research published online in the journal Heart. (2020-02-25)

Could this plaque identifying toothpaste prevent a heart attack or stroke?
For decades, researchers have suggested a link between oral health and inflammatory diseases affecting the entire body -- in particular, heart attacks and strokes. Results of a randomized pilot trial of Plaque HD®, the first toothpaste that identifies plaque so that it can be removed with directed brushing, showed that it produced a statistically significant reduction in C-reactive protein, a sensitive marker for future risks of heart attacks and strokes, among those with elevations at baseline. (2020-02-24)

How to deflect an asteroid
MIT engineers devise a decision map to identify the best mission type to deflect an incoming asteroid. (2020-02-19)

Saliva can be used to predict excess body fat in teenagers
Brazilian researchers found the level of uric acid in saliva to be a good indicator of body fat percentage in a study designed to identify reliable biomarkers that can be used to develop quick noninvasive tests for early detection of chronic diseases. (2020-02-17)

Gum disease, inflammation, hardened arteries may be linked to stroke risk
Two studies raise the possibility that treating gum disease may help prevent the development of artery blockage, thus reducing stroke risk. Patients with gum disease were twice as likely to have a stroke caused by hardening of large arteries within the brain than those without gum disease. Gingivitis, a common gum infection that results in inflammation, was associated with a higher risk of severe blockage of large arteries in the brain that haven't yet caused symptoms. (2020-02-12)

Genetic variants reduce risk of Alzheimer's disease
A DNA study of over 10,000 people by UCL scientists has identified a class of gene variants that appear to protect against Alzheimer's disease. (2020-02-04)

Your gums reveal your diet
Sweet soft drinks and lots of sugar increase the risk of both dental cavities and inflammation of the gums -- known as periodontal diseases -- and if this is the case, then healthy eating habits should be prioritized even more. This is the conclusion of a research result from Aarhus University. (2020-01-30)

New study explores the link between obesity and gum disease
Obesity and gum (periodontal) disease are among the most common non-communicable diseases in the United States -- and studies show these chronic conditions may be related. This new study explores the effect of obesity on non-surgical periodontal care and evaluates potential pathways that may illustrate the connection between the two conditions. (2019-12-03)

Periodontal disease: Patent for new treatment method
New biodegradable rods promise to provide better treatment for periodontal disease. Researchers from the Institute of Pharmacy at Martin Luther University Halle-Wittenberg (MLU) have re-combined an already approved active ingredient and filed for a patent for their invention together with two Fraunhofer Institutes from Halle. The innovation would spare patients from having many side effects. Their findings were published in the ''International Journal of Pharmaceutics''. (2019-11-25)

Evolution of aesthetic dentistry
One of the main goals of dental treatment is to mimic teeth and design smiles in the most natural and aesthetic manner, based on the individual and specific needs of the patient. The JDR Centennial article 'Evolution of Aesthetic Dentistry' provides a historical review of the evolution of aesthetic dentistry over the past 100 years and highlights advances that have contributed to the science and art of aesthetic dentistry. (2019-10-22)

Tooth loss associated with higher risk of heart disease
Adults who have lost teeth due to nontraumatic reasons may have a higher risk of developing cardiovascular disease according to a presentation at the American College of Cardiology Middle East Conference 2019 together with the 10th Emirates Cardiac Society Congress. The conference is Oct. 3-5 in Dubai, United Arab Emirates. (2019-10-03)

Gum disease linked with higher risk of hypertension
People with gum disease (periodontitis) have a greater likelihood of high blood pressure (hypertension), according to a study published today in Cardiovascular Research, a journal of the European Society of Cardiology (ESC). (2019-09-24)

Oral health effects of tobacco products: Science and regulatory policy proceedings
AADR held the 'Oral Health Effects of Tobacco Products: Science and Regulatory Policy' meeting. The papers resulting from this conference are published in the latest issue of Advances in Dental Research, an e-Supplement to the Journal of Dental Research. (2019-09-20)

Tailored 'cell sheets' to improve post-operative wound closing and healing
Scientists have designed a new method for post-operative wound closing and healing that is both fast and effective. This strategy revolves around engineered 'cell sheets' -- or layers of skin-based cells. The procedure culminates in a wound dressing that is custom made for a specific cut or lesion that can be used to effectively treat open skin areas after surgeries. The findings were published in Scientific Reports on July 18th. (2019-09-18)

Scientists uncover key new molecules that could help to tackle tooth loss and regeneration
New research published in the Journal of Dental Research has shed light on the science behind the formation of the periodontal ligament, which helps keep the tooth stable in the jawbone. This improved understanding will help scientists work towards regenerating the tissues that support teeth. This is a peer-reviewed, observational study conducted in rodent teeth and human cells. (2019-08-30)

What drives inflammation in type 2 diabetes? Not glucose, says new research
Research led by Barbara Nikolajczyk, Ph.D., disproved the conventional wisdom that glucose was the primary driver of chronic inflammation in type 2 diabetes. The data might change opinion of tight glycemic control as the optimal strategy for type 2 diabetes management. (2019-08-21)

The Lancet: Big Sugar and neglect by global health community fuel oral health crisis
Oral health has been isolated from traditional healthcare and health policy for too long, despite the major global public health burden of oral diseases, according to a Lancet Series on Oral Health, published today in The Lancet. Failure of the global health community to prioritise the global burden of oral health has led to calls from Lancet Series authors for the radical reform of dental care, tightened regulation of the sugar industry, and greater transparency around conflict of interests in dental research. (2019-07-18)

Metabolomic profiling of antibody response to periodontal pathogens
At the 97th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 48th Annual Meeting of the American Association for Dental Research (AADR) and the 43rd Annual Meeting of the Canadian Association for Dental Research (CADR), Jaakko Leskela, University of Helsinki, Finland, gave an oral presentation on 'Metabolomic Profiling of Antibody Response to Periodontal Pathogens.' (2019-06-22)

Pathogenesis and treatment of periodontitis: Honoring the legacy of Ricardo Teles
The International Association for Dental Research (IADR) and American Association for Dental Research (AADR) honored the legacy of Ricardo Teles in a symposium at the 97th General Session & Exhibition of the IADR, held in conjunction with the 48th Annual Meeting of the American AADR and the 43rd Annual Meeting of the Canadian Association for Dental Research (CADR). (2019-06-21)

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