Current Peripheral Neuropathy News and Events | Page 23

Current Peripheral Neuropathy News and Events, Peripheral Neuropathy News Articles.
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BGI researchers sequenced the human methylome at single base-pair resolution
DNA methylation plays an important role in many processes such as animal development, X-chromosome inactivation, and carcinogenesis. Understanding the mechanisms and functions of DNA methylation and how it varies from tissue to tissue and between individuals will have profound implications for human health and disease. (2010-11-09)

Armed antibody triggers remissions for Hodgkin's lymphoma
An antibody for CD30 loaded with a cytotoxin shows early evidence of success: 38 percent of patients have an objective response, 25 percent a complete remission. (2010-11-03)

Telomere length affects colorectal cancer risk
Telomeres of some young-onset colorectal cancer patients showed accelerated aging. Other patients had telomeres longer than those of young healthy people. (2010-10-28)

Peripheral induction of Alzheimer's-like brain pathology in mice
Pathological protein deposits linked to Alzheimer's disease and cerebral amyloid angiopathy can be triggered not only by the administration of pathogenic misfolded protein fragments directly into the brain but also by peripheral administration outside the brain. (2010-10-21)

Burn injuries rapidly deplete vitamin E
Severe burn injuries in children have been shown to rapidly deplete the levels of vitamin E in their body's adipose, or fat tissues, a new clinical study has found. Stored levels of this important antioxidant were reduced more in a few weeks than might normally be possible in years. (2010-10-20)

Breaking ball too good to be true
Curveballs curve gradually, but the perception by some hitters of a sharp (2010-10-13)

Research discovers how the deaf have super vision
Deaf or blind people often report enhanced abilities in their remaining senses, but up until now, no one has explained how that could be. Researchers at the University of Western Ontario, led by Stephen Lomber of the Centre for Brain and Mind have discovered there is a causal link between enhanced visual abilities and reorganization of the part of the brain that usually handles auditory input. The findings are published online in Nature Neuroscience. (2010-10-10)

HSAN 1: Identification of new mutations, more accurate diagnosis and improved genetic counseling
VIB researchers at the University of Antwerp have identified several mutations that play an important role in the development of Hereditary Sensory and Autonomous Neuropathy Type 1 (HSAN 1). HSAN 1 is a rare genetic disorder of the peripheral nervous system. Identification of the mutations will lead to a more accurate diagnosis of the disease in patients as well as improved genetic counseling and prenatal diagnostic tests for couples who are carriers and planning a pregnancy. (2010-10-08)

'Paradigm shift' in how physicians treat peripheral artery disease
A balloon angioplasty device that sucks up dangerous plaque debris could trigger a (2010-10-05)

How injured nerves grow themselves back
Unlike nerves of the spinal cord, the peripheral nerves that connect our limbs and organs to the central nervous system have an astonishing ability to regenerate themselves after injury. Now, a new report in the Oct. 1 issue of Cell, a Cell Press publication, offers new insight into how that healing process works. (2010-09-27)

Mayo Clinic finds inflammation causes some postsurgical neuropathies
A new Mayo Clinic study found that nerve inflammation may cause the pain, numbness and weakness following surgical procedures that is known as post-surgical neuropathy. (2010-09-22)

UCSD's Michael Criqui receives award for impact on peripheral arterial disease
The Vascular Disease Foundation has awarded Michael Criqui, M.D., M.P.H., professor and chief of the Division of Preventive Medicine in the Department of Family and Preventive Medicine at the University of California, San Diego, one of its highest honors, the President's Award for Vision. The award was presented at the VDF's annual meeting in Alexandria, Va., on Sept. 20. (2010-09-20)

St. John Hospital enrolls first patient in US in trial of peripheral artery disease device
St. John Hospital and Medical Center in Detroit and Avinger Inc., a medical device company focused on the development of innovative devices to combat peripheral artery disease, announced today the enrollment of the first patient in the CONNECT (Chronic TOtal OcclusioN CrossiNg with thE WildCat CatheTer) clinical trial. The CONNECT trial is a prospective, multicenter, nonrandomized study intended to evaluate the Wildcat Catheter's ability to cross chronic total occlusions in femoropopliteal lesions. (2010-09-13)

IV drips can be left in place
Small intravenous devices commonly used in the hand or arm do not need to be moved routinely every three days. A randomized controlled trial comparing regular relocation with relocation on clinical indication, published in the open-access journal BMC Medicine, found that rates of complications were the same for both regimens. (2010-09-10)

Drug holds promise to halt debilitating condition of diabetes
DPN leads to death of nerves in the extremities of individuals with diabetes. A drug developed at the University of Kansas may be able to stop and even reverse the condition. (2010-09-10)

Terumo Medical Corp. reports first US implant in landmark study enrolling in US and Japan
Terumo Medical Corporation, a US-based subsidiary of Terumo Corporation, today announced the first US patient implant in the Occlusive/Stenotic Peripheral artery REvascularization StudY (OSPREY), which will evaluate the safety and efficacy of its MISAGO Peripheral Self-expanding Stent System for use in the superficial femoral artery. The procedure was performed at the Bradenton Cardiology Center in Bradenton, Fla. The OSPREY clinical trial will simultaneously enroll patients in the US and Japan. (2010-09-09)

Embargoed news from Annals of Internal Medicine
This release includes information about three articles being published in the Sept. 7 issue of Annals of Internal Medicine. The information is not intended to substitute for articles as sources of information. Annals of Internal Medicine attribution is required for all coverage. (2010-09-06)

Award-winning study: Hardening of the arteries doubles the risk of mortality
Most patients don't suspect a thing, and yet they are seriously ill: hardening of the arteries -- peripheral arterial disease -- doubles the risk of premature death and serious cardiovascular events such as heart attack and stroke. This result of the five-year follow-up to the study getABI (German epidemiological trial on ankle brachial index, ABI) was published last year by researchers led by Prof. Dr. Hans-Joachim Trampisch (medical informatics, biometry and epidemiology at the RUB). (2010-08-30)

Less intensive drug schedule as effective as standard treatment for blood cancer in elderly patients, but with fewer side effects
A less intensive bortezomib-based regimen (given once instead of twice per week) followed by maintenance therapy, is as effective as the standard treatment for elderly patients with multiple myeloma, but with fewer serious side effects, and will be a valuable treatment option in these patients, according to an article published online first in the Lancet Oncology. (2010-08-23)

Genetics underlie formation of body's back-up bypass vessels
Researchers at the University of North Carolina at Chapel Hill School of Medicine have uncovered the genetic architecture controlling the growth of the collateral circulation -- the (2010-08-19)

Selected cells from blood or bone marrow may provide a route to healing blood vessels
When envisioning cell therapy for cardiovascular disease, a team of scientists is focusing on cells that nourish blood vessels, rather than on rare stem cells. In experiments with mice, CD31 positive cells from the blood or bone marrow can effectively treat hindlimb ischemia -- a model of peripheral artery disease. This approach has the potential to be safer and less arduous than experimental therapies involving the isolation of stem cells from bone marrow. (2010-08-13)

Sea snail saliva may become new treatment for most severe pain
Scientists have developed a new version of a medication, first isolated from the saliva of sea snails, that could be taken in pill form to relieve the most severe forms of pain as effectively as morphine but without risking addiction. An article on the topic appears in the current issue of Chemical & Engineering News, ACS' weekly newsmagazine. (2010-07-28)

NEI/FDA to hold 1-day glaucoma endpoints meeting
The National Eye Institute and the US Food and Drug Administration are sponsoring a Glaucoma Endpoints conference on Sept. 24, 2010, to develop definitions and standards for describing structural changes in the glaucomatous optic nerve and functional changes in vision, as criteria for approval of new glaucoma therapeutics in clinical trials. The one-day meeting will take place at the Natcher Center, National Institutes of Health in Bethesda, Md. (2010-07-27)

Reducing the health risks of obesity without serious side effects
The drug rimonabant was developed as a treatment for the myriad of severe health consequences of obesity, but it was never approved for use in the US because of serious neurological side effects including depression and anxiety. Now, researchers have developed a drug that has the same positive effects as rimonabant in mice on the consequences of obesity that lead to serious health conditions but none of its neurological side effects. (2010-07-26)

Can blocking a frown keep bad feelings at bay?
Your facial expression may tell the world what you are thinking or feeling. But it also affects your ability to understand written language related to emotions, according to research published in the July issue of Psychological Science, a journal of the Association for Psychological Science. (2010-07-19)

New treatment for crippling diabetic Charcot foot
The alarming increase of morbidly obese diabetics is causing more new cases of a debilitating foot deformity called Charcot foot. But a surgical technique that secures foot bones with an external frame has enabled more than 90 percent of patients to walk normally again. (2010-07-14)

Lu receives grant from Research to Prevent Blindness organization
Qingxian Lu, Ph.D., assistant professor of ophthalmology and visual sciences at the University of Louisville School of Medicine, has received the $60,000 William and Mary Greve Special Scholar Award from the Research to Prevent Blindness organization. The funds will go toward Lu's research in retinitis pigmentosa, a group of genetic disorders that can lead to night blindness, loss of peripheral vision and total blindness. (2010-07-14)

U-M researchers identify gene mutation that causes rare form of deafness
Researchers have identified a gene mutation that causes a rare form of hearing loss known as auditory neuropathy, according to U-M Medical School scientists. (2010-07-12)

New discovery in nerve regrowth
Faculty of Medicine scientists have discovered a way to enhance nerve regeneration in the peripheral nervous system. This discovery could lead to new treatments for nerve damage caused by diabetes or traumatic injuries. Peripheral nerves connect the brain and spinal cord to the body, and without them, there is no movement or sensation. Peripheral nerve damage is common and often irreversible. This discovery is published in the July 7 edition of the Journal of Neuroscience. (2010-07-12)

Experimental obesity drug avoids brain effects that troubled predecessors
A second-generation experimental anti-obesity and diabetes drug has shown promise in reducing body weight in rodents just as effectively as the predecessor rimonabant while avoiding the risk of psychiatric side effects that led to the withdrawal of rimonabant from the market and stopped further development of other brain-penetrating drugs of its type. (2010-07-12)

Cholesterol's other way out
Many of us are simply overloaded with cholesterol, and now a report in the July issue of Cell Metabolism brings what might be good news: There is more than one way to get rid of that cholesterol, which can otherwise lead to atherosclerosis and heart disease. (2010-07-07)

Intensive therapy improves some outcomes for patients with established type 2 diabetes but also increases risk of death, weight gain, and hypoglycemia (from ACCORD study)
An analysis of data from the ACCORD study into intensive therapy of blood glucose (sugar) shows that the benefits of such therapy need to be balanced against the increase in total and cardiovascular disease-related mortality, increased weight gain, and high risk for severe hypoglycemia (low blood sugar). The study is published online first by the Lancet to coincide with presentation at the American Diabetes Association meeting. (2010-06-29)

Near-normal blood sugar target did not delay risk of organ damage in people with diabetes
In people with longstanding type 2 diabetes who are at high risk for heart attack and stroke, lowering blood sugar to near-normal levels did not delay the combined risk of diabetic damage to kidneys, eyes or nerves, but did delay several other signs of diabetic damage, a study has found. The intensive glucose treatment was compared with standard glucose control. (2010-06-29)

Intensively lowering glucose: Possible benefits must be weighed against risks
In an analysis from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, results show that the benefits of intensive therapy need to be balanced against the increase in total and cardiovascular disease-related death, increased weight gain, and high risk for severe low blood sugar. The study, published in the Lancet, is written by Dr. Faramarz Ismail-Beigi of University Hospitals Case Medical Center and colleagues for the ACCORD trial group. (2010-06-29)

Stanford study first to show antibodies involved in nerve repair in injuries
Antibodies -- proteins the immune system makes to defend the body against invading pathogens -- have a gentler side nobody knew about until now: They function not only as soldiers but also as nurses. Researchers at the Stanford University School of Medicine now think antibodies' absence in the central nervous system may be a key part of the reason why nerve damage there doesn't get naturally repaired in humans. That insight could lead to new treatments for stroke and spinal-cord trauma. (2010-06-14)

U of M study: Monitoring cholesterol increases life expectancy
A University of Minnesota study definitively shows that those with decreased LDL cholesterol levels can count on an increased life expectancy. The research is published in the May 24 edition of the Annals of Surgery. (2010-06-07)

Circulating tumor cells correlate with poorer survival in pancreatic cancer patients
Fox Chase Cancer Center investigators find that pancreatic cancer patients who have circulating tumor cells tend to have worse outcomes than patients without circulating tumor cells. Additionally, the team has uncovered evidence that not all circulating tumor cells are the same, and some may predict worse outcomes than others. (2010-05-28)

Study pinpoints new role of molecule in the health of body's back-up blood circulation
Researchers at the University of North Carolina at Chapel Hill School of Medicine have discovered that the abundance of collateral blood vessels in a healthy individual and their growth or remodeling into (2010-05-26)

Exercise may keep cancer patients healthier during, after treatment
Breast and prostate cancer patients who regularly exercise during and after cancer treatment report having a better quality of life and being less fatigued, according to researchers at Henry Ford Hospital. (2010-05-20)

LungPoint system results presented at American Thoracic Society 2010 International Conference
Broncus Technologies Inc., a medical device company focused on developing minimally invasive innovations for lung diseases, announced today at the American Thoracic Society 2010 International Conference the availability of its LungPoint system version 2.1. The bronchoscopic navigation system is featured in three poster presentations at the meeting. These highlight the clinical benefits of using LungPoint to guide the biopsy of lymph nodes and peripheral lesions -- both key to the diagnosis and staging of lung cancer. (2010-05-17)

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