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Current Photodynamic Therapy News and Events, Photodynamic Therapy News Articles.
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Inhibition of NF-kappa B, a key inflammatory protein, reduced radiation toxicity in zebrafish
Directly inhibiting the activity of a key protein mediator of inflammation reduced radiation toxicity in zebrafish embryos, and may ultimately be of help to patients receiving radiation therapy, according to researchers from the Kimmel Cancer Center at Jefferson. (2009-09-01)

AMI: The scale of the problem
Acute myocardial infarction remains one of the leading causes of death in the Western world, with prevalence predicted to increase dramatically in developing countries, especially India and China. (2009-09-01)

Men experience sexual dysfunction during hepatitis C therapy
Sexual impairment is common among men with chronic hepatitis C undergoing antiviral therapy. (2009-09-01)

MADIT-CRT trial
Asymptomatic or mildly symptomatic cardiac patients randomized to an implanted cardiac resynchronization device with defibrillator have a 34 percent lower risk of heart failure or death than those receiving a standard implanted cardioverter defibrillator, according to results from the MADIT-CRT study. (2009-09-01)

Diabetic patients require global care
Diabetes mellitus-associated coronary artery disease is assuming epidemic proportions, especially in western countries. Both coronary revascularization and medical management have improved tremendously over the last decade and the respective role in the diabetic population is not well defined. This aspect was investigated in the BARI 2D study. (2009-08-30)

Hormone therapy for prostate cancer patients with heart conditions linked to increased death risk
Men with coronary artery disease-induced congestive heart failure or heart attack who receive hormone therapy before or along with radiation therapy for treatment of prostate cancer have an associated increased risk of death, according to a study in the Aug. 26 issue of JAMA. (2009-08-25)

Long-term tamoxifen use increases risk of an aggressive, hard to treat type of second breast cancer
While long-term tamoxifen use among breast cancer survivors decreases their risk of developing the most common, less aggressive type of second breast cancer, such use is associated with a more than four-fold increased risk of a more aggressive, difficult-to-treat type of cancer in the breast opposite, or contralateral, to the initial tumor. (2009-08-25)

Genetically engineered bacteria are sweet success against IBD
For the first time, scientists have used a genetically engineered (2009-08-20)

Living longer and happier
A new study from the University of Missouri may shed light on how to increase the level and quality of activity in the elderly. In the study, published in this week's edition of PLoS ONE, MU researchers found that gene therapy with a proven (2009-08-19)

Asian spice could reduce breast cancer risk in women exposed to hormone replacement therapy
Previous studies have found that post-menopausal women who have taken a combined estrogen and progestin hormone replacement therapy have increased their risk of developing progestin-accelerated breast tumors. Now, University of Missouri researchers have found that curcumin, a popular Indian spice derived from the turmeric root, could reduce the cancer risk for women after exposure to hormone replacement therapy. (2009-07-13)

Risk of tuberculosis from arthritis medication examined
Treatment with anti-tumor necrosis factor agents is recognized as a risk factor for tuberculosis in patients with immune-mediated inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, psoriatic arthritis and psoriasis. (2009-06-30)

New therapy found to prevent heart failure
A landmark study has successfully demonstrated a 29 percent reduction in heart failure or death in patients with heart disease who received an implanted cardiac resynchronization therapy device with defibrillator (CRT-D) vs. patients who received only an implanted cardiac defibrillator (ICD-only). (2009-06-23)

Novel light-sensitive compounds show promise for cancer therapy
Chemists at UC Santa Cruz have developed novel compounds that show promise for photodynamic cancer therapy, which uses light-activated drugs to kill tumor cells. The new compounds, called dye-sensitized ruthenium nitrosyls, are absorbed by cancer cells and respond to specific wavelengths of light by releasing nitric oxide, which triggers cell death. (2009-06-16)

Hormone therapy may confer more aggressive properties to prostate tumors
Hormone therapy is often given to patients with advanced prostate cancer. While it is true that the treatment prevents growth of the tumor, it also changes its properties. Some of these changes may result in the tumor becoming more aggressive and more liable to form metastases. This is one of the conclusion of a thesis presented at the Sahlgrenska Academy, University of Gothenburg, Sweden. (2009-06-10)

Partnership to accelerate Trudeau Institute discoveries to patient care
The Trudeau Institute and Health Research Inc. have established a unique partnership aimed at advancing the commercialization of medical and scientific discoveries made at the institute to maximize their benefit to public health worldwide. (2009-06-03)

NEJM study finds radiofrequency ablation can reverse Barrett's esophagus, reduce cancer risk
Patients who have gastroesophageal reflux disease for a prolonged period have an increased risk of developing Barrett's esophagus, a pre-cancerous condition where the tissue lining the esophagus becomes damaged by stomach acid and transformed into something like the inside of the stomach. New research finds that radiofrequency ablation -- an endoscopic procedure involving targeted thermal energy -- was very successful at restoring the esophagus and reducing risk for cancer. (2009-06-02)

Mayo Clinic finds new pathology tests double sensitivity to detect bile duct and pancreatic cancers
Pancreatic cancer and bile duct cancer are difficult to diagnose and often fatal because they are discovered in the advanced stages of the disease. Researchers have developed new tests that double the ability to detect bile duct and pancreatic cancers, according to a Mayo Clinic study published in the June issue of Gastroenterology. (2009-06-01)

New treatment option for patients with chronic hepatitis C
A new combination therapy of daily consensus interferon and ribavirin is effective for some people with chronic hepatitis C who do not respond to standard therapy. (2009-05-28)

Why some prostate cancer returns
A study being presented this week at ASCO finds that men with a low oxygen supply to their tumor have a higher chance of the prostate cancer returning, as found by increasing prostate-specific antigen levels following treatment. (2009-05-27)

New therapy substitutes missing protein in those with muscular dystrophy
Researchers at the University of Minnesota Medical School have discovered a new therapy that shows potential to treat people with Duchenne muscular dystrophy, a fatal disease and the most common form of muscular dystrophy in children. (2009-05-26)

ASNTR comments on the NIH guidelines for human stem cells research, MSC7997
The membership of the American Society for Neural Therapy and Repair is supportive of the new NIH guidelines (MSC7997) which allow NIH-funded research for human embryonic stem cells derived from embryos created by in vitro fertilization for reproductive purposes and that are no longer needed for reproductive purposes. We believe that stem cells have tremendous scientific and therapeutic potential and new stem cell lines are essential for allowing their full potential to be realised. (2009-05-20)

Cognitive behavior therapy appears beneficial for long-term treatment of insomnia
For patients with persistent insomnia, a combination of cognitive behavior therapy and the medication zolpidem for 6 weeks was associated with improvement in sleep, although for a longer treatment period CBT alone was more beneficial, according to a study in the May 20 issue of JAMA. (2009-05-19)

Low-income breast cancer patients skipping hormonal therapy, increasing their risks
Many low-income women are failing to take the hormonal therapy prescribed as part of their breast cancer treatment, possibly lowering their survival rates, according to a study led by a researcher in the Duke Comprehensive Cancer Center. (2009-05-18)

2-week course of sleep aid increases CPAP adherence in OSA patients at 6 months
New research suggests that patients newly diagnosed with obstructive sleep apnea who use a short-course of the sleep aid, eszopiclone, when beginning continuous positive airway pressure therapy, are more adherent with therapy in six months. (2009-05-17)

Moving gene therapy forward with mobile DNA
VIB researchers connected to the Katholieke Universiteit Leuven in collaboration with colleagues at the Max Delbruck Center in Berlin have developed a new nonviral gene technology approach. This approach overcomes side-effects associated with the current viral vectors, such as inflammation or the development of cancer. The result offers new hope for optimizing gene therapy as a possible cure for specific diseases, such as genetic disorders and cancer. (2009-05-03)

Prostate cancer therapy increases risk of fractures and cardiovascular-related death
Prostate cancer patients who undergo therapy to decrease testosterone levels increase their risk of developing bone- and heart-related side effects compared to patients who do not take these medications, according to a new analysis. (2009-04-27)

Mayo Clinic researcher says improved detection of bladder tumors reduces cancer recurrence
Making tumors inside the bladder fluoresce red under blue light allows physicians to more easily find and remove them, substantially reducing the rate at which these cancers come back, says a Mayo Clinic physician who is presenting results of a large, multicenter international clinical trial. (2009-04-26)

CBT and BT: Some effect against chronic pain
Cognitive behavior therapy and behavior therapy show some effect in helping the disability associated with chronic pain, according to a Cochrane Systematic Review. The researchers assessed the use of CBT and BT on chronic pain, mood and disability. (2009-04-14)

New therapies expected to help reduce future visual burden of age-related eye disease
The prevalence of the eye disease age-related macular degeneration is projected to increase substantially by 2050, but the use of new therapies is expected to help mitigate its effects on vision, according to results of simulation modeling reported in the April issue of Archives of Ophthalmology, one of the JAMA/Archives journals. (2009-04-13)

Gene therapy appears safe to regenerate gum tissue
Scientists at the University of Michigan have developed a method of gene delivery that appears safe for regenerating tooth-supporting gum tissue -- a discovery that assuages one of the biggest safety concerns surrounding gene therapy research and tissue engineering. (2009-04-07)

2 nondrug treatments appear to reduce depression after heart surgery
Two nonpharmacological interventions -- cognitive behavior therapy and supportive stress management -- appear more effective than usual care for treating depression after coronary artery bypass surgery, according to a report in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals. (2009-04-06)

Stem cell innovation at risk
Despite great hopes for stem cell therapy, major structural and cultural changes within the NHS are needed if it is to succeed in the UK. Currently the chances of getting effective treatments into routine use in the short-term are small and the industry is at serious risk of (2009-04-06)

More compelling evidence on why earlier HIV treatment lengthens survival
A study showing improved survival of starting antiretroviral treatment earlier than current US recommendations is being reported in the April 30 issue of the New England Journal of Medicine. The study found that not starting HIV patients at a CD4 count greater than 500 cells per cubic millimeter increased risk of death by 94 percent. (2009-04-02)

Potential magic bullet for MRSA treatment
Attaching an antimicrobial drug, which is activated by light, to a peptide that binds to bacteria and stops them making toxins, produced a (2009-03-31)

New radiation-free targeted therapy detects and eliminates breast cancer tumors in mice
Combining a compound known as a gallium corrole with a protein carrier results in a targeted cancer therapy that is able to detect and eliminate tumors in mice with seemingly fewer side effects than other breast-cancer treatments, says a team of researchers from the California Institute of Technology (Caltech), the Israel Institute of Technology (Technion) and the Cedars-Sinai Medical Center. (2009-03-30)

New study suggests Rx estrogen delivery through the skin may show safety benefits as opposed to oral delivery
Transdermal delivery of estrogen therapy available by prescription (2009-03-26)

The egg makes sure that sperm don't get too old
In contrast to women, men are fertile throughout life, but research at the Sahlgrenska Academy, University of Gothenburg, Sweden, has now shown that a fertilizing sperm can get help from the egg to rejuvenate. The result is an important step towards future stem cell therapy. (2009-03-25)

NICE SUGAR: Intensive insulin therapy risks
Intensive insulin therapy significantly increases the risk of hypoglycemia in critically ill patients, found a new study in CMAJ. (2009-03-24)

2-day results predict ultimate response to therapy in chronic hepatitis C
A new study suggests that previously noted low rates of successful hepatitis C virus therapy in African-Americans are in large part due to very early differences in the antiviral activity induced by interferon. The study is published in the April 15 issue of the Journal of Infectious Diseases, now available online. (2009-03-20)

Maggot therapy similar to standard care for leg ulcers
Larval (maggot) therapy has similar health benefits and costs compared with a standard treatment for leg ulcers, find two studies published on bmj.com today. (2009-03-19)

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