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Weight loss drug shows positive effect on diabetes
'Now we report that, when added to lifestyle interventions, lorcaserin significantly reduced incidence of diabetes, increased rates of diabetes remission, and reduced the risk of diabetic microvascular complications.' (2018-10-04)
Study shows how lixisenatide slows or prevents damage to the kidneys in patients with type 2 diabetes and cardiovascular disease
New research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) and published simultaneously in The Lancet Diabetes & Endocrinology shows how the glucose-lowering drug lixisenatide can slow or prevent damage to the kidneys in macro-albuminuric patients with type 2 diabetes mellitus (T2DM) and cardiovascular disease. (2018-10-03)
Study finds albiglutide reduces cardiovascular events in patients with type 2 diabetes and existing cardiovascular disease
New research presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD) and published in The Lancet shows that treatment with albiglutide (a type of drug called a glucagon-like peptide 1 receptor agonist) results in fewer cardiovascular events in people with type 2 diabetes and existing cardiovascular disease than treatment with placebo. (2018-10-02)
Non-small cell lung cancer patients see improved survival with durvalumab
Non-small cell lung cancer patients survive longer when their treatment includes durvalumab following platinum-based chemoradiotherapy, according to research led by Moffitt Cancer Center. (2018-09-27)
Study finds that a lifestyle intervention may mitigate PFAS-related weight gain
A new study finds that perfluoroalkyl and polyfluoroalkyl substances (PFASs) are associated with increases in weight, but exercise and diet may reduce the obesogenic effects of these environmental contaminants. (2018-09-25)
Common painkiller not effective for chronic pain after traumatic nerve injury
A new study out today in the Journal of Neurology finds that pregabalin is not effective in controlling the chronic pain that sometimes develops following traumatic nerve injury. (2018-09-24)
Aspirin found not to prolong healthy aging
Taking a low-dose aspirin daily does not prolong healthy living in older adults, according to findings from the ASPirin in Reducing Events in the Elderly (ASPREE) trial published online Sept. (2018-09-17)
Daily low-dose aspirin found to have no effect on healthy life span in older people
In a clinical trial to determine the effects of daily low-dose aspirin in healthy older adults without previous cardiovascular events, aspirin did not prolong healthy, independent living free of dementia or physical disability. (2018-09-16)
Scientific analysis shows probiotic use is associated with fewer antibiotic prescriptions
New analysis shows that infants and children who receive probiotics as a preventative measure are less likely to receive antibiotic prescriptions. (2018-09-14)
BPA exposure in US-approved levels may alter insulin response in non-diabetic adults
In a first study of its kind study, researchers have found that a common chemical consumers are exposed to several times a day may be altering insulin release. (2018-09-13)
Sugar pills relieve pain for chronic pain patients
Someday doctors may prescribe sugar pills for certain chronic pain patients based on their brain anatomy and psychology. (2018-09-12)
High dose folic acid does not prevent pre-eclampsia in high risk women
Taking high dose folic acid supplements in later pregnancy (beyond the first trimester) does not prevent pre-eclampsia in women at high risk for this condition, finds a randomized controlled trial published by The BMJ today. (2018-09-12)
Common anti-smoking treatment makes no difference in shisha tobacco addiction
Researchers at the University of York has shown that a drug commonly used to help smokers overcome addiction to cigarettes does not have the same effect in shisha smokers. (2018-09-06)
Single-dose drug can shorten flu symptoms by about a day, studies suggest
A single dose of a new influenza drug can significantly shorten the duration of the illness in teens and adults, according to a study published in the prestigious New England Journal of Medicine. (2018-09-06)
Synthetic DNA vaccine effective against influenza A virus subtype
Currently available vaccines for the prevention of seasonal influenza virus infection have limited ability to induce immunity against diverse H3N2 viruses, an influenza A subtype that has led to high morbidity and mortality in recent years. (2018-09-06)
Nerve pain in the legs? Medical marijuana may alter brain connections, bring relief
When medical marijuana is taken for chronic nerve pain, it may provide pain relief by reducing connections between the areas of the brain that process emotions and sensory signals, according to a study published in the Sept. (2018-09-05)
New research: Ketamine activates opioid system to treat depression
A new study appearing online today from the American Journal of Psychiatry finds that ketamine's acute antidepressant effect requires opioid system activation, the first time that a receptor site has been shown in humans to be necessary for any antidepressant's mechanism of action. (2018-08-29)
Study finds multiple sclerosis drug slows brain shrinkage
Results from a clinical trial of more than 250 participants with progressive multiple sclerosis (MS) revealed that ibudilast was better than a placebo in slowing down brain shrinkage. (2018-08-29)
Chest pain drug falls short in preventing first episode of ventricular arrhythmia or death
A trial of more than 1,000 patients with implantable cardioverter defibrillators found that the drug ranolazine (used to treat chest pain; brand name Ranexa®) was safe but didn't decrease the likelihood of the first occurrence of ventricular arrhythmias or death in this high-risk population. (2018-08-28)
Antithrombin drug not effective in heart failure with sinus rhythm and coronary disease
Munich, Germany -- Aug. 27, 2018: The antithrombin drug rivaroxaban does not reduce the risk of a composite endpoint of survival, myocardial infarction and stroke after an episode of worsening heart failure in patients with heart failure, sinus rhythm, and coronary artery disease, according to late breaking results from the COMMANDER HF trial presented today in a Hot Line Session at ESC Congress 2018 and with simultaneous publication in NEJM. (2018-08-27)
Researchers discover first treatment to improve survival in rare heart condition
Munich, Germany -- Aug. 27, 2018: Tafamidis is the first treatment to improve survival and reduce hospitalisations in a rare heart condition called transthyretin amyloid cardiomyopathy, according to late breaking research presented today in a Hot Line Session at ESC Congress 2018 and published in the New England Journal of Medicine. (2018-08-27)
Weight loss drug does not increase cardiovascular events
A weight loss drug does not increase cardiovascular events, according to late breaking results from the CAMELLIA-TIMI 61 trial1 presented today in a Hot Line Session at ESC Congress2 and published in the New England Journal of Medicine. (2018-08-26)
Extended use of oral anticoagulant after hospital discharge reduces non-fatal blood clots
Munich, Germany -- Aug. 26, 2018: The use of an oral anticoagulant medicine in medically ill patients for 45 days following their discharge from the hospital reduces the rate of non-fatal symptomatic blood clots with no impact on fatal blood clots, according to late breaking results from the MARINER trial presented today in a Hot Line Session at ESC Congress 2018 and published in The New England Journal of Medicine. (2018-08-26)
Jury still out on aspirin a day to prevent heart attack and stroke
Munich, Germany -- 26 Aug 2018: The jury is still out on whether people at moderate risk of a first heart attack or stroke should take daily aspirin to lower their risk, according to late breaking results from the ARRIVE study presented today in a Hot Line Session at ESC Congress 2018 and with simultaneous publication in the Lancet. (2018-08-26)
Fish oils do not prevent heart attack or strokes in people with diabetes
Munich, Germany - 26 Aug 2018: Fish oil supplements do not prevent heart attacks or strokes in patients with diabetes, according to late breaking results from the ASCEND trial presented today in a Hot Line Session at ESC Congress 20181 and published in the New England Journal of Medicine. (2018-08-26)
ARRIVE trial of daily aspirin does not show lower risk of first cardiovascular event
Findings from ARRIVE, a randomized, controlled clinical trial of the use of daily aspirin to prevent a first cardiovascular event among more than 12,500 participants considered to be at moderate cardiovascular risk, were presented at the European Society of Cardiology meeting. (2018-08-26)
Weight loss drug shows no increased risk in cardiovascular outcomes
For the first time, investigators report that a weight loss drug led to weight loss without increasing the incidence of heart attacks, strokes and death from heart disease in a population of people who are especially at risk for cardiovascular events. (2018-08-26)
Prospect of a new treatment for rheumatoid arthritis
An international research group led by Charité -- Universitätsmedizin Berlin has completed testing a new drug to treat rheumatoid arthritis. (2018-08-23)
New study shows encouraging correlations between a high Omega-3 Index and depression
New research published in the August edition of the Journal of the American College of Cardiology's Heart Failure issue found significant correlations between blood levels of EPA plus DHA omega-3s in 'cognitive' (as opposed to 'somatic') depression among heart failure subjects. (2018-08-22)
Changes in gut microbiome in only one subset of helminth-infected patients
Over the last decade, it's become clearer than ever that bacteria in the human gut-- collectively termed the microbiome--play a key role in health and disease. (2018-08-09)
Exenatide treatment alleviated symptoms of depression in patients
Non-motor symptoms of Parkinson's disease (PD), such as depression, apathy, cognitive impairment, sleep disorders, and sensory symptoms, can have a greater impact on health-related quality of life than motor deficits. (2018-08-01)
Cannabis does not improve breathlessness during exercise in patients with advanced COPD
Inhaled vaporized cannabis does not appear to improve or worsen exercise performance and activity-related breathlessness in patients with advanced chronic obstructive pulmonary disease (COPD), according to a randomized controlled trial published online in the Annals of the American Thoracic Society. (2018-07-27)
The dark side of antibiotic ciprofloxacin
Researchers have found that ciprofloxacin, a widely prescribed antibiotic, increases the risk of tears and rupture on the main artery of the body, the aorta, in a mouse model of human aortic aneurysms and dissections, a disease that carries high risk of death from aortic rupture. (2018-07-25)
Can treatment for depression after a heart attack reduce the long-term risk of another cardiac event
Depression has been associated with poorer medical outcomes for patients with acute coronary syndrome (ACS), including heart attack and unstable angina. (2018-07-24)
Most common shoulder operation is no more beneficial than placebo surgery
In a landmark study published this week in the BMJ, Finnish researchers show that one of the most common surgical procedures in the Western world is probably unnecessary. (2018-07-19)
Study: ADHD drugs do not improve cognition in healthy college students
Contrary to popular belief across college campuses, attention deficit hyperactivity disorder (ADHD) medications may fail to improve cognition in healthy students and actually can impair functioning, according to a study by researchers at the University of Rhode Island and Brown University. (2018-07-19)
Association of monthly high-dose vitamin D supplementation and cancer risk
Monthly high-dose vitamin D supplementation without calcium for up to four years wasn't associated with reduced cancer risk among adults in New Zealand. (2018-07-19)
The scent of coffee appears to boost performance in math
Research at Stevens Institute of Technology reveals that the scent of coffee alone may help people perform better on the analytical portion of the Graduate Management Aptitude Test, or GMAT, a computer adaptive test required by many business schools. (2018-07-17)
Algorithm identifies patients best suited for antidepressants
Results of a new study bring us closer to identifying individuals likely to benefit from antidepressants. (2018-07-17)
New ALS therapy in clinical trials
New research led by Washington University School of Medicine in St. (2018-07-16)
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