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Testosterone therapy may help improve pain in men with low testosterone
Testosterone therapy is associated with decreased pain perception in men with low testosterone levels related to opioid (narcotic) pain relievers (analgesics), a new study finds. (2013-06-17)
Dietary supplement linked to increased muscle mass in the elderly
A supplemental beverage used to treat muscle-wasting may help boost muscle mass among the elderly, according to a new study. (2013-06-15)
Estrogen replacement therapy helps reduce anxiety in anorexia nervosa
Estrogen replacement therapy is associated with a significant decrease in anxiety symptoms among girls with anorexia nervosa, a new clinical trial finds. (2013-06-15)
Weight loss drug added to diet and exercise improves blood sugar control
The new weight loss drug lorcaserin appears to improve blood sugar control in nondiabetic, overweight individuals, independent of the amount of weight they lose, a new study finds. (2013-06-15)
Long-term apremilast demonstrates continued efficacy in patients with psoriatic arthritis
New data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism show that apremilast administered to patients with psoriatic arthritis continues to demonstrate meaningful clinical responses beyond 24 weeks. (2013-06-12)
Significant improvements in psoriatic arthritis with ustekinumab
New PSUMMIT 2 data first presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism, further demonstrate the efficacy of ustekinumab in Psoriatic Arthritis. (2013-06-12)
Antiviral drug protects people who inject drugs from HIV infection
The first trial to assess whether preventative treatment with HIV drugs could affect rates of HIV infection in people who inject drugs has found that daily tablets of tenofovir disoproxil fumarate (tenofovir), an anti-retroviral drug, reduced HIV incidence by nearly half (48.9 percent) compared to placebo, according to new results published Online First in The Lancet. (2013-06-12)
Bevacizumab offers no benefit for newly diagnosed glioblastoma, M.D. Anderson-led study finds
Bevacizumab (Avastin) failed to increase overall survival or statistically significant progression-free survival for glioblastoma patients in the frontline setting. (2013-06-02)
Therapy that heats and destroys bone tumors eases patients' pain
Patients with cancer that has spread to their bones are often treated with radiation therapy to reduce pain. (2013-06-02)
Targeted therapy sorafenib shows success in advanced differentiated thyroid cancer patients
The kidney and liver cancer drug sorafenib holds metastatic thyroid cancer at bay for nearly twice as long as a placebo, according to results of a randomized phase III trial, which will be presented today by a researcher from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania in a plenary session during the American Society of Clinical Oncology's annual meeting. (2013-06-02)
Osteoporosis drug aids young people with cystic fibrosis not helped by standard treatments
The first randomised trial to investigate the treatment of low bone density in young people with cystic fibrosis (CF), published Online First in The Lancet Respiratory Medicine, provides compelling evidence that alendronate (a drug that curbs bone loss) is safe and can help increase bone mineral density in young patients with CF after standard treatment with calcium and vitamin D has failed. (2013-06-01)
Quitting smoking: Licensed medications are effective
Nicotine replacement therapy and other licensed drugs can help people quit smoking, according to a new systematic review published in The Cochrane Library. (2013-05-30)
First-ever enterovirus 71 vaccine protects young children
The first enterovirus 71 (EV71) vaccine candidate to reach phase 3 clinical testing provides young Chinese children with significant protection against disease caused by EV71, a growing public-health threat which has caused over 6 million cases of hand, foot, and mouth disease and 2,000 deaths worldwide over the last decade, according new research published Online First in The Lancet. (2013-05-28)
Levosimendan improves event free survival by 50 percent in end-stage heart failure
Ambulatory levosimendan improves event free survival by 50 percent compared to placebo, according to results from the LevoRep Study presented today during the late breaking trial session1 of the Heart Failure Congress 2013. (2013-05-27)
RELAX-AHF shows first positive findings in HFpEF patients
Serelaxin may be more effective for relieving dyspnea in heart failure with preserved ejection fraction than reduced during the first 24 hours, according to results from RELAX-AHF presented in today's late breaking trial session1 at the Heart Failure Congress 2013. (2013-05-26)
First drug to improve heart failure mortality in over a decade
Coenzyme Q10 decreases all cause mortality by half, according to the results of a multicenter randomized double blind trial presented today at Heart Failure 2013 congress. (2013-05-24)
Successful results in developing oral vaccine against diarrhea
The University of Gothenburg Vaccine Research Institute announces successful results in a placebo controlled phase I study of an oral, inactivated Escherichia coli diarrhea vaccine. (2013-05-22)
Treatment with A1-PI slows the progression of emphysema in Alpha-1 antitrypsin deficiency
Treatment with an Alpha-1 proteinase inhibitor, a naturally occurring protein that protects lung tissue from breakdown and protects the lung's elasticity, is effective in slowing the progression of emphysema in patients with Alpha-1 antitrypsin deficiency, a life-threatening genetic disorder, according to a new study presented at the 2013 American Thoracic Society International Conference. (2013-05-21)
Antidepressant reduces stress-induced heart condition
A drug commonly used to treat depression and anxiety may improve a stress-related heart condition in people with stable coronary heart disease, according to researchers at Duke Medicine. (2013-05-21)
Monoclonal antibody appears effective and safe in asthma Phase IIa trial
A novel approach to obstructing the runaway inflammatory response implicated in some types of asthma has shown promise in a Phase IIa clinical trial, according to US researchers. (2013-05-21)
Antibiotic therapy appears beneficial for patients with COPD
Extended use of a common antibiotic may prolong the time between hospitalizations for patients suffering from chronic obstructive pulmonary disease, according to a post-hoc analysis of a multicenter study which compared the hospitalization rates of patients treated with a 12-month course of azithromycin to the rates of those treated with placebo. (2013-05-21)
Treatment with antidepressant results in lower rate of mental stress-induced cardiac ischemia
Among patients with stable coronary heart disease and mental stress-induced myocardial ischemia (MSIMI), 6 weeks of treatment with the antidepressant escitalopram, compared with placebo, resulted in a lower rate of MSIMI, according to a study in the May 22/29 issue of JAMA. (2013-05-21)
Diabetes drug tested in Parkinson's disease patients
In this issue of the Journal of Clinical Investigation, Dr. (2013-05-20)
Treatment of sleep apnea improves glucose levels in prediabetes
Optimal treatment of sleep apnea in patients with prediabetes improves blood sugar (glucose) levels and thus can reduce cardiometabolic risk, according to a study to be presented at the ATS 2013 International Conference in Philadelphia. (2013-05-19)
Ketamine shows significant therapeutic benefit in people with treatment-resistant depression
Patients with treatment-resistant major depression saw dramatic improvement in their illness after treatment with ketamine, an anesthetic, according to the largest ketamine clinical trial to date led by researchers from the Icahn School of Medicine at Mount Sinai. (2013-05-18)
World first clinical trial supports use of Kava to treat anxiety
A world-first completed clinical study by an Australian team has found Kava, a medicinal South Pacific plant, significantly reduced the symptoms of people suffering anxiety. (2013-05-11)
Oral drops can give kids needle-free relief from asthma, allergies
Allergy shots are commonly used to treat children with severe environmental allergies and asthma, but under-the-tongue drops may offer yet another beneficial -- and stick-free -- option for pediatric allergy sufferers, according to a Johns Hopkins Children's Center review of existing scientific evidence. (2013-05-06)
Study evaluates effect of different supplements on reducing risk of progression to advanced AMD
In a large, multicenter, randomized clinical trial that included persons at high risk for progression to advanced age-related macular degeneration (AMD), adding the carotenoids lutein and zeaxanthin, the omega-3 fatty acids DHA and EPA, or both to a formulation of antioxidant vitamins and minerals that has shown effectiveness in reducing risk did not further reduce risk of progression to advanced AMD, according to a study published by JAMA. (2013-05-05)
Vitamin C may head off lung problems in babies born to pregnant smokers
Pregnant women are advised not to smoke during pregnancy because it can harm the baby's lungs and lead to wheezing and asthma, among other problems. (2013-05-04)
Cochrane review finds no benefit of evening primrose oil for treating eczema
Research into the complementary therapies evening primrose oil and borage oil shows little, if any, benefit for people with eczema compared with placebo, according to a new systematic review. (2013-04-29)
First comprehensive analysis reveals long-term effectiveness of SERMs for preventing breast cancer
Selective oestrogen receptor modulators (SERMs: tamoxifen, raloxifene, arzoxifene, and lasofoxifene) significantly reduce the risk of developing the most common type of breast cancer among women at both high and average risk of the disease* both during treatment, and for at least 5 years after stopping, according to the first comprehensive analysis of all SERM prevention trials to date published Online First in The Lancet. (2013-04-29)
New studies examine caffeine's effect on cognitive tasks, food pairing
Since 1977, there has been a 70 percent increase in caffeine consumption among children and adolescents. (2013-04-22)
Anxious about life? Tylenol may do the trick
Researchers have found a new potential use for the over-the-counter pain drug Tylenol. (2013-04-16)
Outcomes for treating heart failure with cell therapy, high-dose ultrasound
Treatment that consisted of shock wave (procedure using high-dose ultrasound)-mediated preconditioning of the target heart tissue prior to administration of bone marrow-derived mononuclear cells was associated with significant, albeit modest improvement in left ventricular ejection fraction (a measure of how well the left ventricle of the heart pumps with each contraction) after four months in patients with chronic postinfarction heart failure. (2013-04-16)
Study suggests dexmedetomidine before surgery reduced remifentanil-induced hyperalgesia
Dexmedetomidine is a highly selective alpha-2 adrenergic agonist that has been shown to decrease the intensity of opioid-induced hyperalgesia (OIH). (2013-04-11)
Minocycline, an antibiotic, improves behavior for children with fragile X syndrome
Minocycline, an older, broad-spectrum antibiotic in the tetracycline family, provides meaningful improvements as a therapeutic for children with fragile X syndrome, a study by researchers at the UC Davis MIND Institute has found. (2013-04-08)
Antibiotic brings some improvement in fragile X syndrome, reports JDBP
The antibiotic drug minocycline yields (2013-04-08)
Effectiveness of a spray that greatly improves dry mouth sensation caused by anti-depressants
Scientists from the universities of Granada and Murcia have confirmed the effectiveness of a product containing 1% malic acid that stimulates saliva production in patients with medication-induced xerostomy (dry mouth). (2013-04-03)
Medication duloxetine helps reduce pain from chemotherapy
Among patients with painful chemotherapy-induced peripheral neuropathy, use of the anti-depressant drug duloxetine for five weeks resulted in a greater reduction in pain compared with placebo, according to a study in the Apr. (2013-04-02)
Investigational vaccine not effective in reducing post-operative staph infections
Use of a vaccine to prevent Staphylococcus aureus infections among patients undergoing cardiothoracic surgery did not reduce the rate of serious postoperative S. aureus infections compared with placebo and was associated with increased mortality among patients who developed S. aureus infections, according to a study in the Apr. (2013-04-02)
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