Current Pneumonia News and Events

Current Pneumonia News and Events, Pneumonia News Articles.
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Scientists identify potential contributor to hyper immune responses in patients with severe COVID-19
Researchers have pinpointed a helper T cell population in the lungs of patients with severe COVID-19 that may be central to the development of hyperinflammation, lung injury, and subsequent acute respiratory distress syndrome (ARDS) during disease (2021-02-23)

Long-term exposure to low levels of air pollution increases risk of heart and lung disease
Analysis of records for more than 63 million Medicare enrollees from 2000 to 2016 finds long-term exposure to air pollution had a significant impact on the number of people hospitalized for cardiac and respiratory conditions. Researchers examined three components of air pollution: fine particulate matter, nitrogen dioxide and ozone. Even levels lower than national standards affected heart and respiratory illnesses. (2021-02-22)

RUDN University veterinarians tested a new drug against pneumonia in calves
Respiratory tract diseases in young animals of the cattle are a big issue for world agriculture and food safety because a bacterium that causes them is resistant to most antibiotics. A team of veterinarians from RUDN University developed and tested a complex preparation called gentaminoseleferon that could help treat respiratory infection in calves. (2021-02-10)

Arizona economic burden of valley fever totals $736 million
Expenses for the fungal disease endemic to the Southwest can skyrocket for people whose diagnosis is delayed, leading to more serious infection or death. (2021-02-09)

Biosensors to detect P. jirovecii, responsible for Pneumocystis pneumonia
Currently, the detection of the fungus in patients, who may be asymptomatic carriers until they develop pneumonia, uses the PCR technique, which takes several hours and requires adequate facilities and qualified personnel. However, the application of nanotechnology now makes it possible to develop more sensitive and efficient biosensors to detect specific sequences corresponding to pathogens responsible for infectious diseases in a shorter time and without the need for major infrastructure. (2021-02-05)

Electronic health records can be valuable predictor of those likeliest to die from COVID
A study by Massachusetts General Hospital identifies key predictors of COVID-19 mortality among different age groups from patient longitudinal medical records. Predictive analytics based on electronic health records could prove valuable in allocating and distributing limited resources in the time of a pandemic. (2021-02-04)

CT imaging features of patients infected with 2019 novel coronavirus
CT Imaging Features of Patients Infected with 2019 Novel Coronavirus https://doi.org/10.15212/bioi-2020-0038 Announcing a new publication for BIO Integration journal. In this opinion article the authors Tianhong Yao, Huirong Lin, Jingsong Mao, Shuaidong Huo and Gang Liu from Xiamen University, Xiamen, China discuss CT imaging features of patients infected with 2019 novel coronavirus. (2021-01-26)

Hospital worker flu shots could mean fewer deaths
Research shows that state laws promoting flu vaccinations for hospital workers can substantially reduce the number of influenza-related deaths. (2021-01-26)

COVID-19 warnings were on Twitter well before the outbreak of the pandemic
A new study of researchers at IMT School for Advanced Studies Lucca, published in Scientific Reports, has identified tracks of increasing concern about pneumonia cases on posts published on Twitter in seven countries, between the end of 2019 and the beginning of 2020. The analysis of the posts shows that the ''whistleblowing'' came precisely from the geographical regions where the primary outbreaks later developed. (2021-01-25)

ECMO/CRRT in the treatment of critically ill SARS-CoV-2 pneumonia patients
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.1267, Hai Zou and Shengqing Li from the Institute of Pulmonary and Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai, China consider ECMO/CRRT combined support in the treatment of critically ill SARS-CoV-2 pneumonia patients. (2021-01-22)

Study finds genetic clues to pneumonia risk and COVID-19 disparities
Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences. (2021-01-21)

DNA test can quickly identify pneumonia in patients with severe COVID-19, aiding faster treatment
Researchers have developed a DNA test to quickly identify secondary infections in COVID-19 patients, who have double the risk of developing pneumonia while on ventilation than non-COVID-19 patients. (2021-01-15)

Why COVID-19 pneumonia lasts longer, causes more damage than typical pneumonia
COVID pneumonia is significantly different from pneumonia caused by other causes, reports a new study in Nature. It shows how hijacks the lungs' own immune cells and uses them to spread across the lung over weeks. The infection leaves damage in its wake and fuels the fever, low blood pressure and damage to the kidneys, brain, heart and other organs in patients with COVID-19. Scientists discovered a target for treating COVID pneumonia and a clinical trial is underway at Northwestern. (2021-01-11)

Fatal health threat to young African children reduced by innovative artistic intervention
The fatal threat from diarrhoea and pneumonia to young children in the world's poorer countries can be drastically reduced by using traditional performing arts to encourage mothers to provide youngsters with safe food and water, a new study reveals. (2021-01-07)

Analysis of SARS-CoV-2 immune response several months post-infection hints at protective immunity
Researchers who studied antibody and immune cell responses in more than 180 men and women who had recovered from COVID-19 report these patients' immune memory to the virus - across all immune cell types studied - was measurable for up to 8 months after symptoms appeared. (2021-01-06)

State laws promoting flu vaccination for hospital workers may help prevent deaths from flu and pneum
Research suggests that state laws promoting influenza vaccination for hospital workers can be effective in preventing deaths from pneumonia and influenza, particularly among the elderly. Findings from a quasi-experimental observational study are published in Annals of Internal Medicine. (2021-01-04)

An explanation for the lack of blood oxygenation detected in many COVID-19 patients
Researchers at the Seville Institute of Biomedicine (IBIS) describe the presence in the human carotid body, the organ that senses oxygen in the blood, of the protein (ECA2) through which SARS-CoV-2 infects cells. (2020-12-29)

New study links cadmium to more severe flu, pneumonia infections
High levels of cadmium, a chemical found in cigarettes and in contaminated vegetables, are associated with higher death rates in patients with influenza or pneumonia--and may increase the severity of COVID-19 and other respiratory viruses, according to a new study. (2020-12-16)

How to stop infections caused by carbapenemase-producing bacteria
The authors aimed to evaluate in vivo the efficacy of imipenem plus meropenem in an experimental murine model of sepsis caused by clinical isolates of carbapenemase-producing A. baumannii. The results of this study show that the combination of imipenem plus meropenem could be effective in the treatment of infections caused by strains of carbapenemase-producing A. baumannii (OXA-23 and OXA-58). (2020-12-16)

Study uncovers two phases of infection in patients with severe COVID-19 pneumonia
To analyze SARS-CoV-2 at the tissue level, scientists examined lung specimens from 24 patients who succumbed to COVID-19. The analyses revealed two phases of infection in the patients: an early phase defined by high levels of virus in the lungs, and a later phase in which the virus is no longer present, but the damage to the lungs is too severe for recovery. (2020-12-16)

First 10 days after leaving hospital carry high risk for COVID-19 patients, study finds
In the first months after their COVID-19 hospital stay, patients face a high risk of ongoing health problems, hospital readmission and death, a growing number of studies shows. But the first week and a half may be especially dangerous, a new study finds. COVID-19 patients had a 40% to 60% higher risk of readmission or death in the first 10 days, compared with similar patients treated during the same months for heart failure or pneumonia. (2020-12-14)

Large US study confirms COVID-19 complications: lung, kidney and cardiovascular issues
A large study of patients in the United States who contracted coronavirus disease 2019 (COVID-19) confirms many complications of the disease, according to new research in CMAJ (Canadian Medical Association Journal). (2020-12-08)

Coronavirus pneumonia and pulmonary thromboembolism
Announcing a new publication for BIO Integration journal. In this article the authors Mingkang Yao; Phei Er Saw and Shanping Jiang from Sun Yat-Sen University, Guangzhou, China review Coronavirus Pneumonia and Pulmonary Thromboembolism. (2020-12-08)

Scientists shed new light on how lung bacteria defend against pneumonia
New insight on how bacteria in the lungs protect against invading pathogens has been published today in the open-access eLife journal. (2020-12-08)

New study explains important cause of fatal influenza
It is largely unknown why influenza infections lead to an increased risk of bacterial pneumonia. Researchers at Karolinska Institutet in Sweden have now described important findings leading to so-called superinfections, which claim many lives around the world every year. The study is published in the journal PNAS, Proceedings of the National Academy of Sciences, and can also contribute to research on COVID-19. (2020-11-25)

Fiji's vaccine program reduces childhood death and illness: study
Fiji's national vaccine program against pneumonia, a serious lung condition, and rotavirus, a common disease which causes severe diarrhoea and vomiting, has reduced illness and death, new research shows. (2020-11-25)

T-cell abnormalities in severe COVID-19 cases
There appears to be some kind of T cell abnormality in critically ill COVID-19 patients but specific details are unclear. To shed some light on the problem, researchers performed a genetic analysis of T cells from lung tissue of COVID-19 patients. They found abnormalities that resulted in T cell overreaction that may cause severe pneumonia. The research is expected to lead to new methods for avoiding severe pneumonia caused by coronavirus infections. (2020-11-20)

Just hours of training triples doctor confidence in use of handheld ultrasound devices
Filling a training gap, a Penn Medicine doctor created a geriatric medicine-centered course for point-of-care-ultrasound (POCUS) devices that doubled doctor confidence. (2020-11-17)

Effect of fluvoxamine vs placebo on clinical deterioration in outpatients with symptomatic COVID-19
This randomized trial compares the effects of fluvoxamine, a selective serotonin reuptake inhibitor with immunomodulatory effects, versus placebo on a composite of dyspnea or pneumonia and oxygen desaturation among adult outpatients with polymerase chain reaction-confirmed mild COVID-19 illness. (2020-11-12)

Mimicking SARS-CoV-2 nasal infection in monkeys
A new rhesus macaque animal model recapitulates the clinical and pathological manifestations of coronavirus disease 2019 (COVID-19) observed in humans by mimicking natural infection via the nasal route, according to a study published November 12 in the open-access journal PLOS Pathogens by Longding Liu, Qihan Li, Zhanlong He, and colleagues. As noted by the authors, the new animal model could lead to effective treatments or vaccines for COVID-19, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). (2020-11-12)

Electrical stimulation reduces swallowing problems in patients with neurological conditions
Using electrical stimulation in the throats of patients recovering from conditions such as strokes or head injuries will help to relieve swallowing problems, leading to a quicker recovery time, according to a new study. (2020-11-10)

Many with lupus at high risk for adverse reactions to pneumocystis pneumonia drug
New research shows that adults with systemic lupus erythematosus, who receive trimethoprim-sulfamethoxazole (TMP-SMX), a prophylactic therapy to help prevent pneumocystis pneumonia, are at high risk for adverse reactions to the drug, particularly if they are also positive for anti-Smith (anti-Sm) antibodies. Details of the study was presented at ACR Convergence, the American College of Rheumatology's annual meeting. (2020-11-06)

Amount of COVID viral RNA detected at hospital admission predicts how patients will fare
A new study published online in the Annals of the American Thoracic Society examines whether the amount of RNA, or genomic load, of SARS-CoV-2 detected in swab tests of patients being admitted to the hospital with viral pneumonia is associated with more severe COVID-19. SARS-CoV-2 is the virus that causes COVID-19. Previous studies on this question have had conflicting results. (2020-10-29)

Genetic analysis system yields new insights into bacterial pneumonia
A team of infectious disease researchers has developed a new method to identify virulence genes in Streptococcus pneumoniae, the leading cause of bacterial pneumonia. Using this technique in a mouse model of pneumonia, they were able to gain new insights into the progression of the disease and its interaction with the flu virus. (2020-10-28)

Tocilizumab doesn't ease symptoms or prevent death in moderately ill COVID-19 inpatients
The drug tocilizumab (Actemra) does not reduce the need for breathing assistance with mechanical ventilation or prevent death in moderately ill hospitalized patients with COVID-19, according to a study by researchers at Massachusetts General Hospital. The study, published in the New England Journal of Medicine, casts doubt on earlier research suggesting that tocilizumab, which is commonly prescribed for rheumatoid arthritis and other conditions, might be an effective treatment for patients with worsening cases of COVID-19. (2020-10-21)

Tocilizumab vs standard care on preventing worsening in patients hospitalized with COVID-19 pneumonia
Researchers in this randomized clinical trial compared the effect of early administration of tocilizumab with standard therapy in preventing clinical worsening in patients hospitalized with COVID-19 pneumonia. (2020-10-20)

Effect of tocilizumab in adults hospitalized with COVID-19 with moderate or severe pneumonia
This randomized clinical trial assessed whether tocilizumab improves outcomes of patients hospitalized with moderate-to-severe COVID-19 pneumonia compared to usual care. (2020-10-20)

The atomic makeup of M. pneumoniae's 'nap' structure glides into view
Using X-ray crystallography and cryo-electron microscopy, an international team of scientists unravel the atomic structure of the proteins P1 and P40/P90 which make up the ''Nap'' structure - a protein complex that the bacterium M. pneumoniae uses to attach and move around human cells to cause pneumonia. This will allow us to better understand the ''Nap'' structure and develop medicine and vaccines that stop the bacterium from infecting humans. (2020-10-14)

Study shows similar antibody response to key SARS-CoV-2 'spike' protein in COVID-19
New research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) shows that antibody responses to related to the key 'spike' protein of the SARS-CoV-2 virus are similar in COVID-19 patients with and without diabetes, boosting hopes that vaccines involving this same protein will have a high chance of being as effective in vulnerable patients with diabetes as they will be in the general population. (2020-10-08)

Users of blood pressure medicine have a lower risk of dying from influenza and pneumonia
Thousands of Danes use ACE inhibitors or angiotensin II receptor blockers against elevated blood pressure or heart problems, and they may have an improved chance of surviving severe influenza or pneumonia infections. This is shown by a study from the Department of Clinical Epidemiology at Aarhus University and Aarhus University Hospital in Denmark. (2020-10-02)

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