Current Prostate Cancer Screening News and Events

Current Prostate Cancer Screening News and Events, Prostate Cancer Screening News Articles.
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Machine learning method identifies precancerous colon polyps
A machine learning algorithm helps accurately differentiate benign and premalignant colorectal polyps on CT colonography scans, according to a new study. (2021-02-23)

Genetic tool improves estimation of prostate cancer risk in diverse ethnic/racial groups
Scientists at University of California San Diego School of Medicine validated a more inclusive and comprehensive genetic tool, known as a polygenic hazard score (PHS), for predicting age of onset of aggressive prostate cancer. (2021-02-23)

Study shows new treatment pathway to prevent and treat endometrial cancer recurrence
In a new study led by Yale Cancer Center, researchers demonstrate sex hormones and insulin growth factors are associated with recurrence risk of endometrial cancer. (2021-02-23)

Screening for macrocyclic peptides
Macrocyclic peptides are promising candidates for pharmaceuticals, but their screening is difficult. Scientists have now developed an easy-to-use, high-throughput screening assay for cyclic peptides with affinity to ubiquitin, a protein that helps to degrade proteins and induce cell death. The results could lead to novel drug candidates against cancer, according to the study published in the journal Angewandte Chemie. (2021-02-22)

NYUAD researchers develop high throughput paper-based arrays of 3D tumor models
By engineering common filter papers, similar to coffee filters, a team of NYU Abu Dhabi researchers have created high throughput arrays of miniaturized 3D tumor models to replicate key aspects of tumor physiology, which are absent in traditional drug testing platforms. With the new paper-based technology, the formed tumor models can be safely cryopreserved and stored for prolonged periods for on-demand drug testing use. (2021-02-22)

Oncotarget: MEK is a promising target in the basal subtype of bladder cancer
''The @Oncotarget authors demonstrate that MEK inhibitors are a promising targeted therapy for the basal subtype of bladder cancer, and their data indicate that drug screening of 3D cultures provides an important resource for hypothesis generation'' (2021-02-22)

Investment needed to bring down pancreatic cancer death rates in Europe
Researchers have called on European policymakers to make adequate resources available to tackle pancreatic cancer, a disease that is almost invariably fatal and where little progress has been made over the past 40 years. The latest predictions for cancer deaths in the EU and UK for 2021, published in the leading cancer journal Annals of Oncology, show that pancreatic death rates are predicted to remain approximately stable for men, but continue to rise in women in most EU countries. (2021-02-21)

Race, income, education affect access to 3D mammography
Women of minority races and ethnicities and with less education and income have had relatively lower access to 3D mammography, a technology that can improve breast cancer detection and decrease false alarms, according to new research. (2021-02-19)

Mayo Clinic researchers develop test to measure effect of breast cancer gene variants
Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variants in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS). The findings were published today in a study in the American Journal of Human Genetics. (2021-02-19)

Targeting MAPK4 emerges as a promising therapy for prostate cancer
New research opens the possibility that targeting the enzyme MAPK4 in human prostate cancer might provide a novel therapeutic strategy for this disease that is the second leading cause of cancer death in American men. (2021-02-19)

Addressing the biological causes of racial disparities in prostate cancer
A new review published in Cancer Reports examines the biological differences in the development of prostate cancer across ethnicities. (2021-02-18)

Physical conditions linked to psychological distress in patients with cancer
Among patients with cancer, having additional physical comorbidities was linked with a higher risk of experiencing psychological distress. The finding comes from a Psycho-Oncology analysis of 2017 data from the National Health Survey of Spain. (2021-02-18)

How inflammatory signalling molecules contribute to carcinogenesis
A team of MedUni Vienna researchers led by Johannes A. Schmid at the Center for Physiology and Pharmacology, Institute of Vascular Biology and Thrombosis Research, has managed to identify a previously unknown molecular connection between an inflammatory signalling molecule and one of the main oncogenes. The study has been published in the leading journal 'Molecular Cancer'. (2021-02-17)

Scientists able to see how potential cancer treatment reacts in single cell
Using a 185 metre beamline at the Diamond synchrotron, researchers could see how Osmium, a rare precious metal that could be used for cancer treatments, reacts in a single human lung cancer cell. This is a major step forward in discovering new anti-cancer drugs for researchers at the University of Warwick. (2021-02-17)

Toward a disease-sniffing device that rivals a dog's nose
A new system can detect the chemical and microbial content of an air sample with even greater sensitivity than a dog's nose. Researchers at MIT and elsewhere coupled this to a machine-learning process that can identify the distinctive characteristics of the disease-bearing samples. (2021-02-17)

Neural network could help clinicians look for 'ugly duckling' pre-cancerous skin lesions
A neural network system that analyzes photographs can rank and distinguish suspicious, potentially precancerous skin lesions, which can turn into the deadly skin malignancy melanoma if not caught and removed early. (2021-02-17)

Study demonstrates the reasons to screen children with cancer for inherited cancer genes
Experts at MSK Kids, the pediatric oncology program at MSK, have found that inherited cancer genes are more common than expected in children with cancer. (2021-02-16)

Fixer-upper: Understanding the DNA repair toolkit to chart cancer evolution
DNA repair pathways exist to correct molecular damage caused by internal and external factors. However, any damage to these pathways can result in the creation of tumors and specific types of cancers. A group of scientists from China have conducted an extensive investigation into the relationship of DNA repair pathways with cancer evolution. Their review, been published in Cancer Biology & Medicine, also shed light on the potential treatment applications of these mechanisms. (2021-02-16)

Model helps predict which patients will benefit most from PSMA PET scan
A new study led by researchers at the UCLA Jonsson Comprehensive Cancer Center helps identify which patients with prostate cancer will benefit most from the use of prostate-specific membrane antigen PET imaging, PSMA PET, a novel imaging technique that recently was approved by the U.S. Food and Drug Administration. (2021-02-16)

Moffitt uses mathematical modeling to identify factors that determine adaptive therapy success
In a new article featured on this month's cover of Cancer Research, Moffitt Cancer Center researchers, in collaboration with Oxford University, report results from their study using mathematical modeling to show that cell turnover impacts drug resistance and is an important factor that governs the success of adaptive therapy. (2021-02-15)

Exercise now proven to have mental health benefits for prostate cancer
New Edith Cowan University (ECU) research has found that exercise not only has physical benefits for men with prostate cancer, it also helps reduce symptoms of depression and anxiety. (2021-02-15)

Bacterial degradation of the MYC oncogene -- a new cancer treatment strategy?
Scientists at Lund University have discovered how E. coli bacteria target and degrade the well-known oncogene MYC, which is involved in many forms of cancer. The study is now published in Nature Biotechnology. (2021-02-12)

Liquid biopsy for colorectal cancer could guide therapy for tumors
A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer that has just begun to spread beyond the original tumor. Such a biopsy can detect lingering disease and could serve as a guide for deciding whether a patient should undergo further treatments due to some tumor cells evading an initial attempt to eradicate the cancer. (2021-02-12)

Genomic test helps estimate risk of prostate cancer metastasis, death
A commercially available genomic test may help oncologists better determine which patients with recurrent prostate cancer may benefit from hormone therapy, according to new research from the Johns Hopkins Kimmel Cancer Center and 15 other medical centers. (2021-02-11)

Study: New prostate cancer test could avoid unnecessary biopsies
A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients. (2021-02-11)

Echocardiographic screening for rheumatic heart disease in Nepal
An international research team led by Thomas Pilgrim of the Department of Cardiology at Inselspital has published a much-noticed study on early detection of rheumatic heart disease (RHD) in «JAMA cardiology». The study demonstrates that a significant reduction of RHD can be achieved in schools with systematic echocardiographic screening. (2021-02-11)

Scent detection dogs can identify individuals infected with COVID-19
Scent detection dogs can identify individuals infected with the COVID-19 virus according to a new article in the Journal of Osteopathic Medicine. Findings indicate the dogs could be used to screen for infections in hospitals, senior care facilities, schools, universities, airports, large sporting events or concerts. (2021-02-11)

Why Black men's prostate cancer may be more responsive to immunotherapy
Black men die more often of prostate cancer yet have greater survival benefits from immunotherapy treatment. A new study discovered the reason appears to be an increase of a surprising type of immune cell in the tumor. The findings could lead to immune-based precision medicine treatment for men of all races with localized aggressive and advanced prostate cancer. (2021-02-10)

Oncotarget: Melatonin increases overall survival of prostate cancer patients
'The results of the use of melatonin drugs in palliative treatment of patients with end-stage prostate cancer are shown' (2021-02-10)

Breast cancer death rates stop declining in younger women
Breast cancer death rates have stopped declining for women in the U.S. younger than age 40, ending a trend that existed from 1987 to 2010, according to a new study. Researchers expressed hope that the findings would raise awareness of breast cancer in younger women and spur research into the causes behind the change. (2021-02-09)

New study discovers possible early detection method for elusive ovarian cancer
A study led by researchers at the University of Minnesota Medical School found a way to detect the presence of ovarian cancer in patients using Pap test samples, normally used to detect cervical cancer. (2021-02-09)

Joint radionuclide therapy-immunotherapy approach effective in prostate cancer model
A combination of radionuclide therapy and immunotherapy has proven successful in slowing the progression of prostate cancer and increasing survival time, according to new research published in the February issue of The Journal of Nuclear Medicine. The results of the murine study indicate that radionuclide therapy promotes prostate cancer immunogenicity, provoking a cellular response that makes the tumors more receptive to immunotherapy. (2021-02-08)

HKBU and CUHK launch Spermine Risk Score for prostate cancer diagnosis
Researchers from Hong Kong Baptist University (HKBU) and the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) have jointly developed the Spermine Risk Score which, coupled with the use of a urine test, provides a non-invasive and more reliable method for the diagnosis of prostate cancer. In a study conducted by the researchers, about 37% of the patients, who were ultimately found to have no prostate cancer, can avoid undergoing a prostate biopsy procedure. (2021-02-08)

Identification of three genes that determine the stemness of gastric tissue stem cells
Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages. However, detailed analysis in vivo is difficult, so the molecular mechanisms underlying the stemness of gastric tissue stem cells have remained a mystery. Here, by using organoids that mimic tissue structure and function in vivo and GeCKO screening to inactivate arbitrary genes, Alk, Bclaf3 and Prkra have been identified as genes regulating stemness. (2021-02-08)

Halt cell recycling to treat cancer
Targeting and changing autophagy, otherwise known as cell recycling, has been linked to helping control or diminish certain cancers. Now, University of Cincinnati researchers have shown that completely halting this process in a very aggressive form of breast cancer may improve outcomes for patients one day. (2021-02-08)

Take-at-home tests boost colorectal cancer screening 10x for the underserved
By making it the default to send colorectal cancer screening tests to patients' homes unless they opted out via text message, screening rates increased by more than 1,000 percent (2021-02-08)

Female breast cancer surpasses lung as the most commonly diagnosed cancer worldwide
Cancer ranks as a leading cause of death in every country in the world, and, for the first time, female breast cancer is the most commonly diagnosed cancer, overtaking lung cancer, according to a collaborative report, Global Cancer Statistics 2020, from the American Cancer Society (ACS) and the International Agency for Research on Cancer (IARC). (2021-02-04)

NUI Galway demonstrate the promise of precision genomics in cancer treatment
Researchers at NUI Galway have identified genomic signatures in women developing the most common type of breast cancer that can be associated with long-term survival. The NUI Galway team analysed the genomes of breast cancer patients to look for associations with survival rates using advanced statistical techniques. (2021-02-04)

Book developed at Cincinnati Children's helps identify risks of reading difficulties
A study published in the journal Pediatrics expands validation evidence for a new screening tool that directly engages preschool-age children during clinic visits to assess their early literacy skills. The tool, which is the first of its kind, has the potential to identify reading difficulties as early as possible, target interventions and empower families to help their child at home, according to researchers at Cincinnati Children's Hospital Medical Center. (2021-02-04)

Clinical trial: Using MRI for prostate cancer diagnosis equals or beats current standard
The results of a Phase III randomized clinical trial have shown that when it comes to detecting clinically significant prostate cancer, Magnetic Resonance Imaging (MRI) with targeted biopsies (MRI-TBx) matches the current standard and brings a multitude of advantages. The PRostate Evaluation for Clinically Important Disease: MRI vs Standard Evaluation Procedures (PRECISE) study will help to make prostate cancer diagnosis more accurate and less invasive. (2021-02-04)

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