Current Psoriasis News and Events

Current Psoriasis News and Events, Psoriasis News Articles.
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Developmental origins of eczema and psoriasis discovered
Scientists have created a highly detailed map of skin, which reveals that cellular processes from development are re-activated in cells from patients with eczema and psoriasis inflammatory skin diseases. The study in Science offers potential new drug targets for treating these painful skin diseases and provides a new understanding of inflammatory disease. Part of the global Human Cell Atlas initiative, the research could also provide a template for regenerating healthy skin in the laboratory. (2021-01-21)

Benvitimod cream: a new topical treatment for plaque psoriasis
Psoriasis is a chronic inflammatory skin condition characterized by skin plaques and itching. Currently, the most common topical treatments for psoriasis are corticosteroids and vitamin D3 analogs. But these drugs have various side-effects. A recent phase III clinical trial of the novel non-steroidal compound benvitimod in China, published in Chinese Medical Journal, shows that it is safe and effective and could be a promising new topical treatment for psoriasis. (2021-01-19)

New tool removes chemotherapy drugs from water systems
'What goes in, must come out' is a familiar refrain. It is especially pertinent to the challenges facing UBC researchers who are investigating methods to remove chemicals and pharmaceuticals from public water systems. Cleaning products, organic dyes and pharmaceuticals are finding their ways into water bodies with wide-ranging negative implications to health and the environment, explains Dr. Mohammad Arjmand, an assistant professor of mechanical engineering at UBC Okanagan. (2021-01-18)

Low fitness linked to higher psoriasis risk later in life
In a major register-based study, scientists at University of Gothenburg, Sweden, have now demonstrated a connection between inferior physical fitness in young adults and elevated risk of the autoimmune disease psoriasis. For the male recruits to compulsory military training who were rated as the least fit, the risk of developing psoriasis later was 35 percent higher than for the fittest. (2021-01-12)

Secukinumab in children with plaque psoriasis: Study unsuitable for benefit assessment
Secukinumab in children with plaque psoriasis: study unsuitable for benefit assessment The comparator group was not treated appropriately. Firstly, therapy in this group remained unchanged despite non-response, and secondly, it was continued for longer than approved. (2020-12-04)

What makes psoriasis sore: Novel role of immune system in the disease
More than 130 million people around the globe suffer from psoriasis vulgaris, a chronic condition characterized by skin inflammation, scales, and dry patches. However, its pathology is not fully clear. In a recent study, dermatology researchers from Japan have uncovered a complex cellular mechanism responsible for the onset of psoriasis and highlighted potential therapeutic targets for future treatment. (2020-12-03)

T-ray technology reveals what's getting under your skin
A new method for analysing the structure of skin using a type of radiation known as T-rays could help improve the diagnosis and treatment of skin conditions such as eczema, psoriasis and skin cancer. (2020-11-26)

Stem cell transplantation: undesirable rejection mechanism identified
In the treatment of leukaemia, stem cell transplantation subsequent to chemotherapy and radiation can often engender severe adverse inflammatory reactions - especially in the skin or in the gut, since these so-called barrier organs are more frequently affected. Up until now, the reason for this was unclear. A team of researchers in Vienna has now identified an immune mechanism that is partially responsible for this. (2020-11-19)

Therapeutic drug monitoring does not improve remission for patients starting infliximab
New research presented at ACR Convergence, the American College Rheumatology's annual meeting, showed that patients with rheumatic diseases whose infliximab treatment was individually assessed and adjusted with a new strategy called therapeutic drug monitoring did not achieve remission at higher rates compared to those who received standard care. (2020-11-06)

New evidence shows microbe strain can orally treat systemic inflammation in psoriasis
New data published today shows the first clinical evidence of modulating systemic inflammation by oral delivery of a non-living single strain commensal microbe. (2020-10-29)

Taking the itch out of cancer immunotherapy
Researchers from the University of Tsukuba have determined that PD-1 expression on CD8 T cells is the biological pathway that leads to psoriasis-like dermatitis, an unfavorable side effect of cancer immunotherapy with PD-1 inhibitors. This finding offers hope that blocking this pathway can prevent or reduce the undesirable side effect and help cancer patients continue their treatment with improved quality-of-life. (2020-10-26)

'What wound did ever heal but by degrees?' delayed wound healing due to gene mutations
Scientists at Fujita Health University, Japan, have discovered how deficiencies of the IL-36Ra protein -- caused by mutations in the IL36RN gene -- delay wound healing via the flooding of the wound with several types of immune cells. However, by inhibiting the functioning of proteins and the signaling pathways involved in activating the immune system at a wound, this delay can be offset. These findings could aid efforts to develop ways of regulating wound healing in IL36RN mutation-related skin disorders. (2020-10-26)

Most psoriasis patients taking immunosuppressants survive COVID-19
Patients with psoriasis who are taking drugs that affect their immune system have high rates of survival from COVID-19. According to the first findings from a global registry of psoriasis and COVID-19 patients, led by Guy's and St Thomas' clinicians, over 90% survive. (2020-10-20)

Technique to recover lost single-cell RNA-sequencing information
MIT and Ragon Institute researchers have greatly boosted the amount of information that can be obtained using Seq-Well, a technique for rapidly sequencing RNA from single cells. This advance should enable scientists to learn more about the critical genes expressed in each cell, and to discover subtle differences between healthy and diseased cells for designing new preventions and cures. (2020-10-13)

New efficacies of Ganoderma lucidum: Treatment of skin conditions like atopic dermatitis
Ganoderma lucidum, known as Yeongji mushroom in Korea, has long been used medicinally in China, Japan and Korea. Ganoderic acid, an active ingredient found in the mushroom, is known for its excellence in enhancing the immune function of cells. The Korean research team determined the conditions for enhancing the anti-inflammatory, anti-diabetic, and antioxidant effects of Ganoderma lucidum and confirmed its marketability as an anti-inflammatory agent for the skin. (2020-10-07)

Inflammatory gene provides clue to obesity risk
A gene that helps to control inflammation increases the risk of obesity and could be turned off in mice to stop weight gain, a study from The University of Queensland has found. (2020-09-29)

Children who take steroids at increased risk for diabetes, high blood pressure, blood clots
Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to Rutgers researchers. The Rutgers study is the first to quantify these complications of oral steroids in a nationwide population of children. (2020-09-17)

Biologic therapy for psoriasis may reduce heart disease
Biologic therapy for psoriasis - protein-based infusions to suppress inflammation - was associated with a significant reduction in high-risk plaque in heart arteries, over one-year, according to new research. The positive association between biologic therapy and a decrease in high-risk plaque in heart arteries was significant after adjusting for cardiovascular risk factors and psoriasis severity. (2020-09-15)

TV ads for psoriasis and eczema medications portray few people of color
Commercials from pharmaceutical companies advertising medication to treat psoriasis and eczema lack people from racial and ethnic minorities, according to research from the Perelman School of Medicine at the University of Pennsylvania. (2020-09-15)

Henry ford study finds certain immuno suppressing drugs do not increase risk for COVID-19
Patients on immunosuppressive therapy for common skin and rheumatic diseases like psoriasis and rheumatoid arthritis are not at increased risk for contracting COVID-19 and should continue taking their medicine as prescribed, say Henry Ford Health System dermatology researchers in a study published in the Journal of the American Academy of Dermatology. (2020-09-14)

Nature as a model: Researchers develop novel anti-inflammatory substance
Anti-inflammatory substances based on components of human cells could one day improve treatment in patients. Researchers at the Institute of Pharmacy at Martin Luther University Halle-Wittenberg (MLU) have developed a method for producing those substances with controlled quality. Since the body does not recognise them as foreign substances, they offer advantages over anti-inflammatory drugs such as ibuprofen or diclofenac. The results were published in the ''European Journal of Pharmaceutical Sciences''. (2020-09-09)

The neurons that connect stress, insomnia, and the immune system
Researchers have pinpointed the circuit in the brain that is responsible for sleepless nights in times of stress--and it turns out that circuit does more than make you toss and turn. Their study, done in mice, ties the same neuronal connections that trigger insomnia to a stress-induced weakening of the immune system. (2020-09-09)

Ultraviolet B exposure expands proenkephalin+ regulatory T cells with a healing function
Skin exposure to ultraviolet B (UVB) induces expansion of regulatory T (Treg) cells with immunosuppressive activity. Here researchers found that UVB-expanded skin Treg (UVB-skin Treg) cells had a tissue repair function. UVB-skin Treg cells expressed proenkephalin (PENK) and amphiregulin (AREG), which promoted keratinocyte outgrowth and skin wound healing. Their results provide a new implication in developing a therapy using UVB-skin Treg cells. (2020-09-01)

New strategy against osteoporosis
An international research team has found a new approach that may be able to reduce bone loss in osteoporosis and maintain bone health. (2020-08-05)

Getting under the skin of psoriasis
Psoriasis afflicts millions of people worldwide, but treatments are limited to small molecules like steroids, which can cause skin thinning and lose their effectiveness over time. A Wyss Institute collaboration has circumvented those problems by using a topical ionic liquid to effectively deliver an RNA-based therapy directly into the skin of mice with psoriasis, which reduced multiple psoriasis-related gene products as well as redness and inflammation, resolving the longstanding challenge of delivering nucleic acids into cells. (2020-07-22)

Mount Sinai researcher identifies single gene biomarker to differentiate between atopic dermatitis
Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy. The research will be published online today in the Journal of Allergy and Clinical Immunology. (2020-07-21)

Corrona Psoriasis Registry shares real-world evidence at AAD Virtual Meeting
The Corrona® Psoriasis Registry, a joint collaboration between the National Psoriasis Foundation, NPF, and Corrona, LLC, the leading sponsor of registries in immune-mediated diseases, announces that studies from the registry will be presented at the American Academy of Dermatology Virtual Meeting Experience (AAD VMX) taking place June 12-14, 2020. (2020-06-12)

Case Western Reserve-led research uncovers connections between psoriasis and joint disease
A team led by Case Western Reserve University School of Medicine researchers has made two major discoveries involving psoriasis, a chronic and debilitating skin disease with no known cure. (2020-06-08)

Psoriasis patients' mental health is more than skin-deep
A new study from Umeå University, Sweden, shows that other somatic diseases have even more impact on patients' mental health than their skin symptoms, highlighting the importance of holistic patient care. (2020-06-04)

BIOCAD presents results of clinical trial proving efficacy of netakimab at EULAR 2020
BIOCAD presents results of clinical trial proving efficacy of netakimab in the treatment of psoriatic arthritis at the Annual European Congress of Rheumatology (EULAR 2020). Four abstracts present the results from an international randomized double-blind phase 3 clinical trial (PATERA) which demonstrate netakimab decreases disease activity and reduces skin manifestation of psoriatic arthritis through 24 weeks of therapy. (2020-06-04)

Examining melanoma risk in patients treated with biologics for common inflammatory diseases
This study combined the results of seven studies and compared the risk of melanoma among 34,000 patients treated with biologics and 135,000 patients treated with conventional systemic therapy for rheumatoid arthritis, psoriasis or inflammatory bowel disease. (2020-05-20)

Lipid helps heal the eye's frontline protection
A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common corneal injuries, even when other conditions, like diabetes, make healing difficult, scientists report. (2020-03-26)

A protein that controls inflammation
A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as rheumatoid arthritis, Crohn's disease, and psoriasis. They discovered how the protein A20 prevents inflammation and autoimmunity, not through its enzymatic activities as has been proposed, but through a non-enzymatic mechanism. (2020-03-17)

Microscopic STAR particles offer new potential treatment for skin diseases
A skin cream infused with microscopic particles, named STAR particles, could potentially facilitate better treatment of skin diseases including psoriasis, warts, and certain types of skin cancer. (2020-03-09)

Scientists discover new 'Jekyll and Hyde' immune cell
Scientists at Trinity College Dublin have identified a rare, new cell in the immune system with 'Jekyll and Hyde properties.' These cells play a key protective role in immunity to infection but -- if unregulated -- also mediate tissue damage in autoimmune disorders. The findings should help us design more effective vaccines to prevent infections such as MRSA, and may also assist help us develop of new therapies for autoimmune diseases, such as multiple sclerosis or rheumatoid arthritis. (2020-02-27)

Evaluating risk of cancer in patients with psoriasis, psoriatic arthritis
This observational study was a systematic review and meta-analysis that included 112 studies and examined the association between risk of cancer in patients with psoriasis or psoriatic arthritis, including the risk of specific cancers. (2020-02-19)

Study investigates rates of adverse events for common rheumatoid arthritis drug
Investigators have been able to far more accurately determine rates of adverse events for people taking methotrexate, finding small-to-moderate elevations in risks for skin cancer, gastrointestinal, infectious, lung, and blood adverse events. (2020-02-17)

Right beneath the skin we all have the same bacteria
In the dermis skin layer, the same bacteria are found across age and gender. This has been shown by researchers from the University of Copenhagen in a new study which has studied skin samples from knees and hips. The researchers hope it is a step in the direction of a better understanding of why skin disorders occur. (2020-02-12)

New discovery provides hope for improved multiple sclerosis therapies
Scientists from Trinity College Dublin have made an important discovery that could lead to more effective treatments for people living with multiple sclerosis (MS) and other autoimmune diseases such as psoriasis and rheumatoid arthritis. (2020-02-04)

Discovery could lead to new treatment for rare blood disease
A new study shows cancer cells found in the lesions on the skin of cutaneous T-cell lymphoma patients originate from the blood, not the skin as was believed. The protocol to treat the disease was to eliminate the cancer cells from the skin. Based on the findings, researchers believe it would be more effective to treat the malignant clones in the blood rather than waiting until the cells reach the skin and present as lesions. (2020-01-27)

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