Current Psoriasis News and Events | Page 3

Current Psoriasis News and Events, Psoriasis News Articles.
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Not just for children: Study shows high prevalence of atopic dermatitis among US adults
As many as 16.5 million adults in America suffer from a skin disease known as atopic dermatitis, an inflammatory disease that results in red, itchy skin. The estimate comes from a new study from the Perelman School of Medicine at the University of Pennsylvania, which also projected 6.6 million of these adults have disease that would be classified as moderate to severe, leading to a decrease in quality of life. (2018-10-30)

Psoriasis linked with need for cardiovascular interventions in patients with hypertension
Psoriasis is linked with increased risks of hypertension and cardiovascular disease, but its effect on the course of cardiovascular disease remains unknown. (2018-10-17)

Could treating psoriasis in the future be as easy as going online?
New research from the Keck School of Medicine of USC finds that an online care delivery model is equivalent to in-person care for improving psoriasis symptoms. (2018-10-05)

Stigmatizing views and myths about psoriasis are pervasive in the United States
The stigma associated with the autoimmune disease psoriasis may lead people to avoid patients who show signs of the condition, including not wanting to date, shake hands, or have people in their homes if they suffer from the disease. New multidisciplinary research involving both psychologists and dermatologists from the Perelman School of Medicine at the University of Pennsylvania is the first to examine how common this stigma may be among the general population of the United States as well as among medical students. (2018-08-30)

Molecular switch triggers itch
A new study of male mice published in JNeurosci uncovers two distinct pathways through which a single molecule can cause both itchy and painful skin. The research could inform the development of drugs for a variety of skin diseases. (2018-08-06)

How was Mediterranean diet associated with severity of psoriasis?
Adherence to a Mediterranean diet, an eating plan filled with fruits and vegetables, legumes, cereals, bread, fish, fruit, nuts and extra-virgin olive oil, may be associated with the severity of the skin condition psoriasis. (2018-07-25)

Aggressive immune cells aggravate Parkinson's disease
Parkinson's disease, formerly also referred to as shaking palsy, is one of the most frequent disorders affecting movement and the nervous system. Medical researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have come across a possible cause of the disease - in the patients' immune system. (2018-07-19)

Cancer patients may experience delayed skin effects of anti-PD-1 therapy
Cancer patients receiving anti-PD-1 therapies who develop lesions, eczema, psoriasis, or other forms of auto-immune diseases affecting the skin may experience those adverse reactions on a delay -- sometimes even after treatment has concluded. (2018-07-18)

Having stress-related disorder associated with increased risk of developing autoimmune disease
Stress-related disorders brought on by traumatic or stressful life events were associated with increased risk of developing an autoimmune disease. (2018-06-19)

Racial differences uncovered in debilitating itchy skin condition
An international team led by Johns Hopkins Medicine researchers has conducted what is believed to be the largest detailed published study of people with a poorly understood skin condition known as prurigo nodularis (PN). Such studies collect information on a whole subset of people at once and at a particular point in time. (2018-06-14)

Humira does not improve aortic vascular inflammation in psoriasis patients
An antibody used to treat the skin disease psoriasis and other chronic autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease has no effect on aortic inflammation -- a key marker of future risk of major cardiovascular events -- unlike other antibodies that target different aspects of the immune system. (2018-05-18)

Insight into potential new strategy to target skin diseases like psorias
Research at UT Southwestern has shown that targeting metabolism in growing cells holds promise for the treatment of skin diseases like psoriasis that are characterized by skin overgrowth resulting from excess cell division, known as hyperproliferation. (2018-05-04)

Double-bridged peptides bind any disease target
EPFL scientists have developed a new type of 'double-bridged peptide' that can be tailored to bind tightly to disease targets of interest. The peptides' highly efficient binding, combined with their small size and high stability make them ideal for drug therapies. The work is published in Nature Chemistry. (2018-04-30)

New study shows therapy for psoriasis can reduce heart plaque
Late-breaking clinical science shows common therapy options for psoriasis (PSO) can help reduce coronary plaque. The authors found that not only do the treatments reduce the volume of the plaque, but also the plaque becomes less inflammatory over time harboring fewer characteristics prone to rupture and cause a heart attack. (2018-04-26)

Psoriasis treated with compound derived from immune cells
A compound from the body's own immune cells can treat psoriasis in mice and holds promise for other autoimmune diseases such as multiple sclerosis, according to a new study at Washington University School of Medicine in St. Louis. (2018-04-18)

Drug that treats psoriasis also reduces aortic vascular inflammation
An antibody used to treat the skin disease psoriasis is also effective at reducing aortic inflammation, a key marker of future risk of major cardiovascular events. (2018-02-16)

Scientists shed light on a key molecular mechanism of autoimmune and inflammatory diseases
An international team of researchers led by prof. Savvas Savvides (VIB-UGent Center for Inflammation Research) has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis and Crohn's disease. Focusing on the immunomodulatory cytokine IL-23 they discovered that its pro-inflammatory activity, which underlies a wide range of inflammatory diseases, critically depends on structural activation of the cytokine by its receptor, IL-23R. (2018-01-17)

Normal tissue BRCA1 methylation associated with risk for high-grade ovarian cancer
Normal tissue BRCA1 methylation is associated with risk for high-grade ovarian cancer and may occur as a prenatal event. These findings are published in Annals of Internal Medicine. (2018-01-15)

A repurposed drug could open door to more stem cell transplants
Etanercept, a drug used to treat arthritis and psoriasis, boosted the survival of blood stem cells in a mouse model. The findings provide a strong basis for a clinical trial to see whether etanercept or a similar drug would improve outcomes for people receiving blood stem cell transplants. (2017-12-20)

Racial minorities less likely to see a doctor for psoriasis
Despite the fact that their disease may be more severe, a new study shows minorities are less likely than white Americans to see a doctor for psoriasis treatment. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that black, Asian, and other non-Hispanic minorities are about 40 percent less likely to see a dermatologist for psoriasis than whites. (2017-12-13)

Preventing psoriasis with vanillin
Small amounts of artificial vanilla extract, also known as vanillin, are in a wide range of products, from baked goods to perfumes. But vanillin's versatility doesn't stop there. In a recent mouse study reported in ACS' Journal of Agricultural and Food Chemistry, researchers report that this compound could also prevent or reduce psoriatic skin inflammation. (2017-11-29)

Psoriasis severity linked to increased risk of type 2 diabetes
People with psoriasis are at a higher risk to develop type 2 diabetes than those without psoriasis, and the risk increases dramatically based on the severity of the disease. Researchers from the Perelman School of Medicine at the University of Pennsylvania found people with psoriasis that covers 10 percent of their body or more are 64 percent more likely to develop diabetes than those without psoriasis, independent of traditional risk factors such as body weight. (2017-11-14)

Russian chemists developed a way to synthesize drugs from renewable precursors
The scientists of RUDN University together with their Russian colleagues have developed a new approach to the synthesis of benzofurans from cheap raw materials. Original furans can be produced from wastes of agriculture and wooworking industry, such as sawdust, cobs and other by-products of crop production. The results of the work were described in the article published in Tetrahedron. (2017-11-14)

Protect the skin, build barriers: Old acquaintance in a new role
To ensure the barrier function of the skin, mutual regulation of connections between epidermal cells and a receptor for growth factors is necessary. These findings can help to reduce the effects of inflammatory skin diseases and the decreased barrier function of the aged skin. The mechanism was described by a team of researchers led by Carien Niessen of the Cluster of Excellence for aging research, CECAD/Cologne. The results have been published in Nature Communications. (2017-11-08)

How the skin becomes inflamed
Publishing online this week in Cell Host & Microbe, researchers at Johns Hopkins report the discovery of a key underlying immune mechanism that explains why to how our skin becomes inflamed from conditions such as atopic dermatitis, more commonly known as eczema. Toxin-producing bacteria on the surface of our skin induces a protein that causes our own cells to react and cause inflammation. (2017-11-08)

New psoriatic arthritis treatment guideline presented at the 2017 ACR/ARHP Annual Meeting
Authors of the new American College of Rheumatology (ACR) / National Psoriasis Foundation (NPF) treatment guideline for psoriatic arthritis (PsA) will present their draft recommendations during a session at the 2017 ACR/ARHP Annual Meeting this week in San Diego. The guideline includes pharmacologic and non-pharmacologic recommendations for treating adult patients with active psoriatic arthritis. Both the ACR and NPF anticipate the guideline will play an important role in improving outcomes for individuals living with PsA. (2017-11-04)

Psoriasis (PsO) patients at higher risk for serious liver disease
Compared to controls, patients with psoriasis (PsO) are at higher risk for serious liver disease than patients with rheumatoid arthritis -- two autoimmune diseases often treated with similar drugs that can cause liver damage, reports a study this week in the Journal of Investigative Dermatology from researchers at the Perelman School of Medicine at the University of Pennsylvania. (2017-11-02)

The skinny on lipid immunology
In a new study published in Science Immunology, researchers from Brigham and Women's Hospital and Monash University in Australia reveal new insights into the basis for T cell receptor (TCR) autoreactivity to self-phospholipids, with implications for autoimmune diseases. (2017-10-20)

Inflammation trains the skin to heal faster
Scientists have found that stem cells in the skin remember an injury, helping them close recurring wounds faster. The discovery could advance research and treatment of psoriasis and other inflammatory diseases. (2017-10-18)

Promising new target for treatment of psoriasis is safe, study shows
A protein known to play a significant role in the development of psoriasis can be prevented from functioning without posing a risk to patients, scientists at King's College London have found. The study confirmed that a group of inflammatory proteins called 'IL-36' play a significant role in the development of psoriasis and can, in theory, be blocked without posing a risk to patients. (2017-10-11)

Uncovering why psoriasis recurs
New research by investigators at Brigham and Women's Hospital and Rockefeller University helps address a longstanding question about the inflammatory skin condition psoriasis: Why do skin lesions that have resolved with therapy recur in the same locations after a patient stops using topical steroids? (2017-09-28)

Fire ant venom compounds may lead to skin treatments
Solenopsins, the main toxic components of fire ant venom, chemically resemble ceramides, which are lipid-like molecules essential for maintaining for the barrier function of the skin. Solenopsin analogs can reduce skin thickening and inflammation in a mouse model of psoriasis, Emory and Case Western scientists have shown. (2017-09-11)

Severity of psoriasis linked to increased risk of death
The more the surface area of the body is covered by psoriasis, the greater the risk of death for the patient suffering from the condition, according to a new analysis by researchers in the Perelman School of Medicine at the University of Pennsylvania. Patients with psoriasis on 10 percent or more of their body are at almost double the risk of death. (2017-08-29)

Psoriasis and psychiatric illnesses: What are the links?
A new review examines the potential link between psoriasis and mental health conditions. (2017-08-11)

Breakthrough by scientists finds arthritis drug could treat blood cancer patients
University of Sheffield scientists discover drug used for arthritis could be used to treat blood cancer. Polycythemia vera, a type of blood cancer, affects 3,000 people a year. The breakthrough offers an affordable and effective treatment. (2017-08-03)

New treatment options for common debilitating skin disease Hidradenitis suppurativa
The research team behind the study pinpointed 'Th17' cells as mediating the disease (HS). A number of existing treatments target the same cellular pathway and may also be effective in treating HS. (2017-07-19)

New target could soothe the itch of inflammatory skin conditions
Existing medicines could offer a new way to treat inflammatory skin conditions, researchers at Melbourne's Walter and Eliza Hall Institute and the Royal Melbourne Hospital have revealed. The research team discovered skin inflammation relies on a protein called RIPK1, and could be prevented by depleting this protein. The finding offers hope that drugs targeting RIPK1, which are currently in clinical trials, could offer relief to people with skin conditions such as psoriasis. (2017-07-15)

Pain neuron may protect fungal inflammation and bone destruction
Scientists discovered unexpected functions of pain neuron. Pain neuron may inhibit fungi-induced osteo-inflammation via CGRP-Jdp2 axis. (2017-06-29)

Study finds long-term sustained effect of biological psoriasis treatment
Biological treatment of psoriasis shows a good efficacy in clinical trials. Since most analyses have focused on short-term outcomes of single biological agents, little has been known about long-term outcomes in clinical practice, where switching between biological agents is common. A Swedish study that followed 583 individuals for up to 10 years shows a satisfactory long-term effectiveness of biologic treatments. The findings were recently published in the British Journal of Dermatology. (2017-06-28)

New effective treatments for psoriatic arthritis patients
The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR) 2017 press conference revealed promising data supporting two new drug classes for the treatment of psoriatic arthritis (PsA). (2017-06-16)

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